Gene 16375 (Tetrahymena)
16375
Group:
Other
Family:
Ciliate-A4
Sequence
Protein domains of 16375.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 16375.AA | Ciliate-A4 | 665-955 | 57 | 3.9e-183 | 602.6 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 665-955 Range on HMM: 1-284/284 Sequence Identity: 57% (171 aa) FVYFSSIGEGSFGTVDLYFFKQNKLQESQTKDSNFLKQTWHTSNSTIKNSLPQSQLFSSSQSNQPNVLQFSNLSAQQNENPMIFSSEMQQEQSNIFSSKN |.|..|||||||||||||||.....|.....|.....||||..|....|...|.|...|||..|....|||....||..|.|.||.||||.|...|..|. FYYYTSIGEGSFGTVDLYFFEIDYYQKCNFQDQQQNQQTWHQNNNQNYNQYNQNQYIQSSQQMQQQKQQFSFNQDQQQYNNMMFSQEMQQQQYQKFNQKW SQKNQRDYQYQNQDMANYIEKQQSVYIEKIDSEDSKNTQEEVTAQKFQEMQYLPVACKKIENLEEYQRELFIMQTVKCEYMPKLFYQDLDKQLLFMELGL ||..|..||||||||.|||.|||.||..|| |.|..|||||||||||...||..|||.|||||.|||||||||.|.|.|.||||.|| SQSHQQIYQYQNQDMHNYIQKQQNVYYQKI--------------QQFMKMQYLPVACKKIKTQEEFIRELYIMQTVQCEYMPKLFYYDIDQQILFMEMGL CSLEDLKNDSEENGYKFSDEFTHQILVNLIKAVESLLSN--YNQETQQKQPLFHSDIKPSN-----VMLTVKKYKNQSTCSIKLLLIDYGGSSFALED |||.|||.|||.|.|.||||||..||.|||.|.||.||| |||..|..||||||||||.| .|||||| |.. |.|.|||.|| || ||| CSLYDLKQDSEQNNYCFSDEFTYSILINLIQAIESMLSNKAYNQQEQKHQPLFHSDIKPQNKIQLQIMLTVKKSKEDQQSQIQLMLIDFGGASFQLED |
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| Kinase | 16375.AA | S_TKc | 665-1080 | 10 | 1.1e-05 | -93.41 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 665-1080
Range on HMM: 1-231/231
Sequence Identity: 10% (45 aa)
FVYFSSIGEGSFGTVDLYFFKQNKLQESQTKDSNFLKQTWHTSNSTIKNSLPQSQLFSSSQSNQPNVLQFSNLSAQQNENPMIFSSEMQQEQSNIFSSKN
. ||.|.||.| . | |. .|.
YEILRKIGKGAFGKVYKCRHKK-------TGRIVAIKIIK------------------------------------------------------------
SQKNQRDYQYQNQDMANYIEKQQSVYIEKIDSEDSKNTQEEVTAQKFQEMQYLPVACKKIENLEEYQRELFIMQTVKCEYMPKLFYQDLDKQLLFMELGL
| .||. |.. .... ||.. | . |.| . .
---------------------------------------------------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEY
CSL--EDLKNDSEENGYK-----FSDEFTHQILVNLIKAVESLLSNYNQETQQKQPLFHSDIKPSNVMLTVKKYKNQSTCSIKLLLIDYGGSSFALEDYW
|. ||. ...|.. |. . .. ...|.| . .. | |.||.|..|. . ..| | . . .
CDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYC---------HSHGIIHRDLKPENILLDE-----------HIKICDFGLARQL---TT
AFYTPAFVSAAVWEKLIKRSQSGQCLSWEEIRYAE----------VYAACRSIQFLLVPEQDKELFRKENYNQFLIQYSYLYPKTCSILKQVYFSENIGY
|| ... | | . . . . . . |....|.|
FCGTPWYMAPEVL------------------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------------------------
ISNIYESVLSESEKTLYTGL---NPQ----NIPFES-------HKIF
|.. | . .. .|. | |
---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
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| Kinase | 16375.AA | WEE | 665-679 | 60 | 0.001672 | 7.7 | In-house | 1-15 (297) | Show / Hide |
Range on Protein: 665-679 Range on HMM: 1-15/297 Sequence Identity: 60% (9 aa) FVYFSSIGEGSFGTV | . ..|||||||.| FQEVQKIGEGSFGEV |
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| Kinase | 16375.AA | WEE | 916-937 | 27 | 0.0311 | 3.38 | In-house | 135-171 (297) | Show / Hide |
Range on Protein: 916-937 Range on HMM: 135-171/297 Sequence Identity: 27% (10 aa) HSDIKPSNVMLTVKKYKNQS---------------TC | ||||.|.... |. ||. .| HMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMC |
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