Gene 5409 (Tetrahymena)

5409

Species: Tetrahymena
Alias: 5409, TTHERM_00437530, 49.m00181, 3708.m00031, 437, PreTt05409
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: CAMKK
Subfamily: CAMKK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
5409.AA Protein None 1301 None Fasta, JSON
5409.kin_dom Protein Kinase Domain None 292 None Fasta, JSON
5409.NA RNA None 3906 None Fasta, JSON

Protein domain

Protein domains of 5409.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 5409.AA CAMKK-Unclassified 890-1181 39 7.4e-184 604.26 In-house 1-392 (392) Show / Hide 
Range on Protein: 890-1181
Range on HMM: 1-392/392
Sequence Identity: 39% (156 aa)

YTLIKELGRGACGKVKLGLDEIN-----QKYYAIKVSNKNKLKKKLVSQKINAFTLLEQ--------EIAIMKKVDHPNIVKLHEVIDDSENNKLYL--V
|.....||||..|||||......     ||..||||..|.|||||......||||....        |||||||..||||.||.|||||..|.|.|.  |
YEFLDKLGRGSFGKVKLATRRYTTDDGVQKQFAIKVFKKQKLKKKKFIYNDNAFTMKMKNRLHLVQQEIAIMKKLWHPNICKLYEVIDDPDNDKIYMGQV

MEYMKRGAILSSGYFKATIQSQD--------------PIRYSELYD-DNGKLKNRQNE-------------PKSIDLNSALRYMRHMTLALDYMHNFAQ-
|||...|.|.|..|.|...|..|              |......|. .||||.||||.             |..........|.|.....|.|||||.| 
MEYCQMGQIMSWDYWKQDYQPNDGEIEYFFQTQTEYKPDQFCCQYYNQNGKLHNRQNQKICLFSNQILEMKPYKMHEQYLKKYFRQCCKGLQYMHNFNQA

-------------------ICHRDIKPDNLLIDENDN-----LKVADFGISTLMEKSDET--SSNAGTKAFMAPESWEKKVFKAPPLD------------
                   |.||||||.|.|||..||     .|.||||||..||.....  ..||||..|||||.|.|..||....|            
CSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKENFKYDYNDYSFLPGTFNPLR

---------------IWATGVTLYIMIYGSVPFKEKKLIELKN-EICQKEIVLPP--IPEIPEQAKDLLFRMLDKNPMKRITAKGMLVHPWI
               ||..|||.|.|.|.|.||..|.|.||.. .||||||..||  .|......|||...|.||||.||||...||||||.
KTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCDKNPKKRITIDQMLVHPWF
Kinase 5409.AA CAMKK 890-1181 36 4.5e-174 557.32 In-house 1-396 (396) Show / Hide 
Range on Protein: 890-1181
Range on HMM: 1-396/396
Sequence Identity: 36% (146 aa)

YTLIKELGRGACGKVKLGLDEIN-QKYYAIKVSNK----NKLKKKLVSQ-----------------KINAFTLLEQEIAIMKKVDHPNIVKLHEVIDDSE
|.|.||.|.|..|||||  .|.. ||.||||..||    .|||||....                 ..|.|....||||||||..|||||||.||||| .
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

NNKLYLV-MEYMKRGAILSSGYFKATIQSQDPIRYSELYDDNGKLKNRQNE---PKSIDLNS---------------------ALRYMRHMTLALDYMHN
|.|.|.| |||..|| |..  |.| ..|...|..|.|||.      |||..   ..... .                      | .|.|.....|.|.||
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYS------NRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHN

FAQ-------------------ICHRDIKPDNLLIDEND---NLKVADFGISTLMEKSDETSSN------------AGTKAFMAPESWEK-KV-------
...                   |.||||||.|.||||..   ..|.||||.|. .|..|.|.||            |||.||||||...| .        
YQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGY

-------FKAPPLDIWATGVTLYIMIYGSVPFKEKKLIELKN---EICQKEIVLPP-----------IPEIPEQAKDLLFRMLDKNPMKRITAKGMLVHP
       .. ...||||.|||||....|..||....|..|..   .|....|. |.           .|||.|..|||..|||.|||.||||.. ..|||
KYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHP

WI
|.
WV
Kinase 5409.AA CAMK 895-1181 21 3.1e-78 251.54 In-house 1-425 (425) Show / Hide 
Range on Protein: 895-1181
Range on HMM: 1-425/425
Sequence Identity: 21% (99 aa)

ELGRGACGKVKLGLDEINQ------------KYYAIKVSNKNKLK------------KKLVSQK-------INAFTLLEQEIAIMKK-------VDHPNI
.||||. |||||. .  ..            . .|||. .|.|||            ..   .|        .    ...||.||||       .|||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLHEVIDDSE-----------------NNKLYLVM---EYMKRG--------AILSSGYFKATIQSQDPIRYSELYDDNGKLKNRQNEPKS--------
.||.||..|..                 ....|.||   ||.  |         | . |..       |                               
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEF---D----------------------QFDIVERGR

IDLNSALRYMRHMTLALDYMHNFAQICHRDIKPDNLLIDEND-----------------NLKVADFGISTLMEK------------------------SD
..   | ||.| .  |..|.|.   |.|||.||.|.|.|.|.                 |.|..||| .. ...                         .
FTEREARRYFRQICSAVHYCHSHN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQ

ETSSNAGTKAFMA-PESWEK-------------KVFKAPPLDIWATGVTLYIMIYGSVPFKEK---------------KLIELKNEICQKEIVLPPIPEI
  .   || ..|| ||  ..             |    |. |.|. || ||||  |  || ..               . .  |   .. .   |....|
KMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPI

P--------------------EQAKDLLFRMLDKNPMKRITAKGMLVHPWI
.                    ...|||. .|| ..| ||.|..  | |||.
SCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 5409.AA AGC 890-1181 22 1.6e-76 196.49 In-house 1-395 (395) Show / Hide 
Range on Protein: 890-1181
Range on HMM: 1-395/395
Sequence Identity: 22% (95 aa)

YTLIKELGRGACGKVKLGLDE------INQKYYAIKVSNKNK---LKKK-LVSQKINAFTLLE------QEIAIMKKVD----------HPNIVK-LHEV
. ..| .|.|. ||| |  .        ..||||.|| .| .   .|||  | . .....  .      .|  |..|..          ||.||| ||  
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHW-KQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYS

IDDSENNKLYLVMEYMKRGAILSSGYFKATIQSQDPIRYSELYDDNG-KLKNRQN---EPKSIDLNSALRYMR-------HMTLALDYMHNFAQICHRD-
  | ....||.|||||.|  .  .                 ||   |  |  ..      .. | . |  |.        ...|||.|.|.   | ||| 
FQDKDHTYLYFVMEYMPR-YVN-D-----------------LYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDY

IKPDNLLIDENDNLKVADFGISTLMEKS---------------------------------------------------DETSSNAG--TKAFMAPESWE
.||.|.|.||. ..| .||| .. . ..                                                   | |..  |  |  .||||   
LKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-

KKVFKAPPLDIWA--TGVTLYIMIYGSVPFKEK----------KLIELKNEIC------QKEIVLPPI--------PEIPEQAKDLLFRMLDKNPMKRIT
      .. |.|.   |. .| |..|  ||  .             |. . |.      .... .|.         ... ..||||. ..| |.| ||..
----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLG

----------AKGMLVHPWI
          |.    ||| 
CGGNDFGDKGAEEIKNHPWF
Kinase 5409.AA S_TKc 890-1181 27 1.5e-73 251.54 SMART 1-231 (231) Show / Hide 
Range on Protein: 890-1181
Range on HMM: 1-231/231
Sequence Identity: 27% (84 aa)

YTLIKELGRGACGKVKLGLDEINQKYYAIKVSNKNKLKKKLVSQKINAFTLLEQEIAIMKKVDHPNIVKLHEVIDDSENNKLYLVMEYMKR--GAILSSG
|......|.|| |||... .   ....|||. .                  ...||.|.|| .|||||||..|..|   ..||.||||.    |  ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFD--

YFKATIQSQDPIRYSELYDDNGKLKNRQNEP--KSIDLNSALRYMRHMTLALDYMHNFAQICHRDIKPDNLLIDENDNLKVADFGISTLMEKSDETSSNA
                       .|.|. ..  . ..   | .||. . .||.|.|.  .|.|||.||.|.|.||  ..|..|||.....      ..  
----------------------YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFC

GTKAFMAPESWEKKVFKAPPLDIWATGVTLYIMIYGSVPFKEKKLIELKNEICQKEIVLPPIPEIPEQAKDLLFRMLDKNPMKRITAKGMLV-------H
||  .||||      .  .. |.|. |..||.|..|  ||    . .. . |.            ...|||.. ..|.|.| ||.||   |        |
GTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

PWI
||.
PWF
Kinase 5409.AA Pkinase 890-1181 24 2.2e-67 234.95 Pfam 1-293 (293) Show / Hide 
Range on Protein: 890-1181
Range on HMM: 1-293/293
Sequence Identity: 24% (81 aa)

YTLIKELGRGACGKVKLGLDEINQKYYAIKVSNKNKLKKKLVSQKINAFTLLEQEIAIMKKVDHPNIVKLHEVIDDSENNKLYLVMEYMKRG-------A
|.... .|.|. |.|... .  ..| .|.|. .| . |..   .....     .||.|||...|||||.|...  |  ....|.||||.  |       .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFD

ILSSGYFKATIQSQDPIRYSELYDDNGKLKNRQNEPKSI--DLNSALRYMRHMTLALDYMHNFAQICHRDIKPDNLLIDENDNL----KVADFGISTL--
..|                               . ...  . . . .||. .  .|.|.|.   |.|||.||.|.|||.|...    |..|||.. .  
YIST-----------------------------WRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD

MEKSDETSSNAGTKAFMAPESWEKKVFKAPPLDIWATGVTLYIMIYGSVPFKEK----KLIELKNEICQKEIVLPPIPEI--------------------
  ..  ... .||  .||||   .     |. |.|. |..||.|. |  ||...    . .. .  ||..    .. ..                     
Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFH

--PEQAKDLLFRMLDKNPMKRITAKGMLVHPWI
  .| .||.. ..|.|.| ||.||.  | |||.
NWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 5409.AA Ciliate-E2-Unclassified 890-1181 25 6e-63 215.43 In-house 1-352 (352) Show / Hide 
Range on Protein: 890-1181
Range on HMM: 1-352/352
Sequence Identity: 25% (96 aa)

YTLIKELGRGACGKVKLGLDEINQKYYAIKVSNKNKLKK-KLVSQKINAFTLLEQEIA----------------IMKKVDHPNIVKLHEVIDDSENNKLY
|..|| .|.|. |||..  .. ...|||.|  .|.. .| |.. .|.  . . ..|.                 |..  .||.|||....  | .|  .|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN--IY

LVMEYM-----------------KRGAILSSGYFKATIQSQDPIRYSELYDDNGKLKNRQNEPKSIDLNSAL-----RYMRHMTLALDYMHNFAQICHRD
.||||.                 |                             . | ..... | .. . |.     .|...  ..|.|.|    |.|||
IVMEYCEGGDLWQYIKKRKKQKQK----------------------------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRD

IKPDNLLIDEND---NLKVADFGIST----------------LMEKSDETSSNAGTKAFM----APESWEKKVFKAP---PLDIWATGVTLYIMIYGSVP
|||.|.|.|.|    ..|..|||||                  . |........||  .|    |||  ...    .     |||. || || |..|  |
IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP

FKEKKLIE----------------LKNEICQKEIVLPPIPE------IPEQAKDLLF----RMLDKNPMKRITAKGMLVHPWI
|. .. ..                |...|.||.|  |. |.      ....|||..     .||.||| ||||..  | |||.
FYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 5409.AA Ciliate-E2 890-1181 23 1.8e-62 213.27 In-house 1-365 (365) Show / Hide 
Range on Protein: 890-1181
Range on HMM: 1-365/365
Sequence Identity: 23% (96 aa)

YTLIKELGRGACGKVKLGLDEINQKYYAIKVSNKNK---------LKKKLVSQKIN---AFTLLEQEIAIMK----------------KVDHPNIVKLHE
| .|| .|.|. |.|... .  .|| .|||. . .|          |.|..  ||.       ..||| ||.                ...||||.|..|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VIDDSENNKLYLVMEYMKRGAILS-----SGYFKATIQSQDPIRYSELYDDNGKLKNRQNEPKSIDLNSALRYMRHMTL---------------ALDYMH
.  .  .|..|||||| . |  ..     .  ..  |.                    . . |..... ....|.. .                || |.|
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE--------------------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLH

NFAQICHRDIKPDNLLIDENDNLKVADFGIST-----------------LMEKS----------------DETSSNAGTKAFMAPESWEKKV------FK
.   |.||||||.|.|.     .|..|||.|.                 .|. .                . . . .||  .||||  ..|       .|
SKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQK

APP--LDIWATGVTLYIMIYGSVPFKEKKLIELKNEICQKEIVLP----------------PIPEIPEQAKDLLFR----MLDKNPMKRIT-AKGMLVHP
      |||. ||.||.|..|  ||         ..|.|..| .|                   ......|||. .    ||.|.| |||| ..  | ||
GYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHP

WI
|.
WF
Kinase 5409.AA CAMKL 1036-1181 33 1.2e-51 163.01 In-house 139-297 (297) Show / Hide 
Range on Protein: 1036-1181
Range on HMM: 139-297/297
Sequence Identity: 33% (55 aa)

ALDYMHNFAQICHRDIKPDNLLIDEND--NLKVADFGISTLMEK-----SDETSSNAGTKAFMAPESWEK--KVFKAPPLDIWATGVTLYIMIYGSVPFK
|..|.|.   |.||||||.|.|.|||.  |.|..||| |.....      .  .   |. ..||||  ..  | . .|. |||. ||.|| |..| .||.
AVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFD

EKKL-------IELKNEICQKEIVLPPIP-EIPEQAKDLLFRMLDKNPMKRITAKGMLVHPWI
.  .       | .. ..  .    |||. ... ...||. .|| .||.||.|..  . ||| 
DDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 5409.AA Meta 1046-1181 43 1.7e-51 146.95 In-house 144-287 (287) Show / Hide 
Range on Protein: 1046-1181
Range on HMM: 144-287/287
Sequence Identity: 43% (62 aa)

ICHRDIKPDNLLIDENDNLKVADFGISTLMEKSDETSSN---AGTKAFMAPESW--EKKV-FKAPPLDIWATGVTLYIMIYGSVPFKE--KKLIELKNEI
| |||||| |||...    |.||||.|   | .| . .|   ||| ||||||.   |..  .    ||.||.||||| ...| .||      .. | . |
IIHRDIKPSNLLLNDDGHVKIADFGVSNEFEGDDAFLCNGSTAGTPAFMAPEACSEEQNHFYCGRALDVWAMGVTLYCFVFGQCPFIDKTNYIMCLHDKI

CQKEIVLPPIPEIPEQAKDLLFRMLDKNPMKRITAKGMLVHPWI
 . ... |  ||| |  ||.  ||||||| .||.     .|||.
KNHPVMFPEQPEISEDLKDCIKRMLDKNPEHRIMIPEIKTHPWV
Kinase 5409.AA MARK 1036-1181 37 8e-39 124.64 In-house 116-262 (262) Show / Hide 
Range on Protein: 1036-1181
Range on HMM: 116-262/262
Sequence Identity: 37% (56 aa)

ALDYMHNFAQICHRDIKPDNLLIDEND--NLKVADFGISTLMEKSDETSSNAGTKAFMAPESWEKKVFKAPPLDIWATGVTLYIMIYGSVPFKEKK--LI
|. |.|.   |.||||||.|.|||||   | | .||| |.  .     ..  ||...||||  .||   .|. |||. || ||.|. |..||...   . 
AVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYK

ELKNEICQKEIVLPPIPEIPEQAKDLLFRMLDKNPMKRITAKGMLVHPWI
||. .|   .   |.   .. ....|. |.|  ||..|.|..  . |||.
ELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 5409.AA Meta 890-985 37 5.5e-37 104.32 In-house 1-113 (287) Show / Hide 
Range on Protein: 890-985
Range on HMM: 1-113/287
Sequence Identity: 37% (42 aa)

YTLIKELGRGACGKVKLGLDEINQKYYAIKVSNKNKLKKKLVSQKI-----------------NAFTLLEQEIAIMKKVDHPNIVKLHEVIDDSENNKLY
|.|  |.|.|. |.|||   |  ...||.|. .| ||.|.    .                  |.. .  |||||.|| ||||.||| ||.||   . ||
YRLMEEIGKGSYGVVKLAYNEEDHHHYAMKILSKKKLLKQYGFMRRPPPRGNKPNQGGCIQPRNPLDRVYQEIAILKKLDHPNVVKLVEVLDDPNEDYLY

LVMEYMKRGAILS
.|.|| ..| ...
MVFEYVEKGPVME
Kinase 5409.AA ULK 1011-1181 23 4.8e-34 118.21 In-house 108-324 (324) Show / Hide 
Range on Protein: 1011-1181
Range on HMM: 108-324/324
Sequence Identity: 23% (53 aa)

LKNRQN-----EPKSIDLNSALRYMRHMTLALDYMHNFAQICHRDIKPDNLLIDENDN------------LKVADFGISTLMEKSDETSSNA--------
.|....     |.| .  . |. ....   .. ..|.  .| ||||||.|.|| ...             ||.|||| .   .. ..             
IKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKR

--GTKAFMAPESWEKK-------VFKAPPLDIWATGVTLYIMIYGSVPFKEKKLIELK----NE----------ICQKEIVLP---PIPEIPEQAKDLLF
  ||  .|||. ....        .|.   |||  |. .| |.||..||..    ...    ..          |... |  |   ..| | .. |||. 
IKGTPLYMAPQILQGQGEQKPYYDYKC---DIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIR

RMLDKNPMKRITAKGMLVHPWI
||| ... .||.   .. |||.
RMLQYDEKDRISWEEIFNHPWF
Kinase 5409.AA CAMKL 890-977 36 1.9e-32 100.75 In-house 1-102 (297) Show / Hide 
Range on Protein: 890-977
Range on HMM: 1-102/297
Sequence Identity: 36% (38 aa)

YTLIKELGRGACGKVKLGLD-EINQKYYAIKVSNKNKLKKKLVSQK-------INAFTLLEQEIAIMKKVD---HPNIVKLHEVIDDSEN----NKLYLV
|...|.||.|..|||||...  .... .|||. .|.|.... ...|             ...||.|||...   ||||.||.|||...|.    .|.|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MEY
|||
MEY
Kinase 5409.AA MARK 890-981 39 2e-27 86.82 In-house 1-87 (262) Show / Hide 
Range on Protein: 890-981
Range on HMM: 1-87/262
Sequence Identity: 39% (37 aa)

YTLIKELGRGACGKVKLGLDEINQKYYAIKVSNKNKLKK-KLVSQKINAFTLLEQEIAIMKKVDHPNIVKLHEVID-DSENNKLYLVMEYMKRG
| ..|..| |...||||...   .. .|||. .|.|| . .       ..  .. ||.||||.|||||.||..||. | |....||.|||  .|
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQ-------WMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGG
Kinase 5409.AA ULK 890-977 38 9.2e-22 74.04 In-house 1-98 (324) Show / Hide 
Range on Protein: 890-977
Range on HMM: 1-98/324
Sequence Identity: 38% (38 aa)

YTLIKELGRGACG-KVKLGLDEIN---QKYYAIKVSNKNKLKKKLVSQK-INAFTLLEQEIAIMKKVD---HPN--IVKLHEVIDDSENNKLYLVMEY
| |...|| |. | ||  | ....   ..|.|.|. .|.|..||   |    .  ||..|| |||| .   |||  ||||...  .| .| .|..|||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEY
Kinase 5409.AA TyrKc 890-1181 21 1.6e-14 12.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 890-1181
Range on HMM: 1-280/280
Sequence Identity: 21% (71 aa)

YTLIKELGRGACGKVKLGLDEINQKYYAIKVSNKNKLKKKLVSQKINAFTLLEQEIAIMKKV--DHPNIVKLHEVIDDS-EN----NKLYLVMEYMKRGA
 ||.|.||.|| |.| .|         |.|. ....               . .|. ||.|.  .|||||.|. |. .. .|      |..|||||. |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

ILSSGYFKATIQSQDPIRYSELYDDNGKLKNRQNEPKSIDLNSALRYMRHMTLALDYMHNFAQICHRDIKPDNLLIDENDNLKVADFGISTLMEKS----
 ..  | ...                            . .   | ..       .| |   .. |||.   | |..||   |..||| |   .      
LKD--YLRKHRPK-------------------------LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG

---DETSSNA--GTK-----AFMAPESWEKKVFKAPPLDIWATGVTLY-IMIYGSVPFKE-----KKLIELKNEICQKEIVLPPIPE--------IPEQA
   |  ..    |.|       ||||.. ...|  .  |.|. ||... |. ||  |  .     .. .|. . . ..   .|. |.         |.  
ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV-KQGYRMPQPPNDYPMSFVCCPDEM

KDLLFRMLDKNPMKRITAKGMLVHPWI
 ..  .  . .| .| | .    |  .
YQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 5409.AA Pkinase_Tyr 941-985 44 1.1e-09 33.48 Pfam 50-96 (270) Show / Hide 
Range on Protein: 941-985
Range on HMM: 50-96/270
Sequence Identity: 44% (21 aa)

LEQEIAIMKKV-DHPNIVKLHEVID-DSENNKLYLVMEYMKRGAILS
. .|..|||.  .|||||.|. |.  ..| |..|.|||||. |  |.
FMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD
Kinase 5409.AA Pkinase_Tyr 1055-1101 30 0.003058 11.6 Pfam 141-191 (270) Show / Hide 
Range on Protein: 1055-1101
Range on HMM: 141-191/270
Sequence Identity: 30% (16 aa)

NLLIDENDNLKVADFGISTLMEKSDET-SSNAGTKAF----MAPESWEKKVF
| |..||   |..||| . .... |.   .  |.| .    ||||..  ..|
NCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKF
Kinase 5409.AA Pkinase_Tyr 890-907 50 0.214225 5.35 Pfam 1-18 (270) Show / Hide 
Range on Protein: 890-907
Range on HMM: 1-18/270
Sequence Identity: 50% (9 aa)

YTLIKELGRGACGKVKLG
 |..|.||.|| |.|..|
ITFGKKLGEGAFGEVYKG