Gene 8975 (Tetrahymena)

8975

Species: Tetrahymena
Alias: 3721.m00055, 75.m00173, TTHERM_00564370, 366, PreTt08975, 8975
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: CAMKK
Subfamily: CAMKK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
8975.AA Protein None 394 None Fasta, JSON
8975.kin_dom Protein Kinase Domain None 307 None Fasta, JSON
8975.NA RNA None 1185 None Fasta, JSON

Protein domain

Protein domains of 8975.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 8975.AA CAMKK-Unclassified 86-392 36 8.60000000001e-182 597.41 In-house 1-392 (392) Show / Hide 
Range on Protein: 86-392
Range on HMM: 1-392/392
Sequence Identity: 36% (142 aa)

YELLDKIGSGSFGKIVRVTRSYYEDDGVTISKSIYVFKILKKSQKIIQITDENGQSQLKKELDLLYQELEIYKYLNNVNICKLYQIIDAPYEQTIYL--V
||.|||.|.|||||....||.|..||||.....|.|||. |...|.....|.......|..|.|..||..|.|.|...||||||..||.|....||.  |
YEFLDKLGRGSFGKVKLATRRYTTDDGVQKQFAIKVFKKQKLKKKKFIYNDNAFTMKMKNRLHLVQQEIAIMKKLWHPNICKLYEVIDDPDNDKIYMGQV

MQYCDLGQILNLDEKDQKYYPNT-------------KIDQFIEQTYNISE-------------------QDQYKKREKFAKVIFKQVSQGLKYLHDKK--
|.||. |||...|...|.|.||.             |.|||..|.||..                    ...|| .|  .| .| |...||.|.|...  
MEYCQMGQIMSWDYWKQDYQPNDGEIEYFFQTQTEYKPDQFCCQYYNQNGKLHNRQNQKICLFSNQILEMKPYKMHEQYLKKYFRQCCKGLQYMHNFNQA

-------------------IVNRDIKIDNILGKSIECDKGENFKIIDFSTAVKLKSHHQK-VFGQAGTPAYQSPEVCTKSNDGYDGKA------------
                   |..||||..|||......||||.|||.||...|......|| ....|||.....||...|.|..||...            
CSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKENFKYDYNDYSFLPGTFNPLR

-------------ADIWSLGVTIYCYVNLSLPFLNQPDP----QKLFNSILNDPIQFQTHNSALFLDLINNMCRKNPKERLKIDQVLNHQWF
             |||||||||.||.|..||||......    |.......|.|.|...|.|..|.|||..||.||||.|..|||.|.|.||
KTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCDKNPKKRITIDQMLVHPWF
Kinase 8975.AA CAMKK 86-392 32 2.7e-161 516.03 In-house 1-396 (396) Show / Hide 
Range on Protein: 86-392
Range on HMM: 1-396/396
Sequence Identity: 32% (128 aa)

YELLDKIGSGSFGKIVRVTRSYYE--DDGVTISKSIYVFKILKKSQKIIQITDEN-------GQSQLKKELDLLYQELEIYKYLNNVNICKLYQIIDAPY
|||...||.|.|||. .....|..  .....|.. .|||| |||.|.........       |..|.....|..|||..|.|..|..||.|||..|| |.
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

EQTIYLV-MQYCDLGQILNLDEKDQKYYPNT---------------KIDQFIEQTYNIS-------EQDQYKKREKFAKVIFKQVSQGLKYLH-DKK---
...||.| |.||..|||.......|.|.||.               |..........||       .||||. .| .|. .| .. .||.||| ..|   
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS

----------------IVNRDIKIDNILGKSIECDKGENFKIIDFSTAVKLKSHHQKVFG-----------QAGTPAYQSPEVCTKSNDG----------
                |..||||..||| ....|  ||..||.||..........|....           .|||||.. ||.|.|.|..          
YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGC--GEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRF

---YDGKAADIWSLGVTIYCYVNLSLPFLNQPDPQKLF--NSILNDPIQFQT-------------HNSALFLDLINNMCRKNPKERLKIDQVLNHQWF
   |.|||||||.||||.||.|....||......|...  ..|.||||.|..             ..|... |||..|..|||..|..|.|...|.|.
RFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase 8975.AA S_TKc 86-392 24 4.9e-52 180.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 86-392
Range on HMM: 1-231/231
Sequence Identity: 24% (78 aa)

YELLDKIGSGSFGKIVRVTRSYYEDDGVTISKSIYVFKILKKSQKIIQITDENGQSQLKKELDLLYQELEIYKYLNNVNICKLYQIIDAPYEQTIYLVMQ
||.|.|||.|.|||  ...           .. |.  ||.|                     . ...|..| |  .  ||.||| ...    . .|.|| 
YEILRKIGKGAFGKVYKCRHKK--------TGRIVAIKIIK---------------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVME

YCDL--GQILNLDEKDQKYYPNTKIDQFIEQTYNISEQDQYKKREKFAKVIFKQVSQGLKYLHDKKIVNRDIKIDNILGKSIECDKGENFKIIDFSTAVK
|||   |  . . .| ..  .. ...                  |  |. ...|. ..|.|.|...|. ||.| .|||  .       . ||.||  | .
YCDGDLGDLFDYIKKRGRHGLRFPFP------------------E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQ

LKSHHQKVFGQAGTPAYQSPEVCTKSNDGYDGKAADIWSLGVTIYCYVNLSLPFLNQPDPQKLFNSILNDPIQFQTHNSALFLDLINNMCRKNPKERLKI
|         . ||| | .|||.     ||.....|.||.|...|  .    ||    ..|..|. |.          |  ..|.|.....|.|..|. .
L-------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA

DQVLN-------HQWF
 ..|.       |.||
-EALQDEWDIKCHPWF
Kinase 8975.AA CAMK 91-392 19 6.3e-50 158.67 In-house 1-425 (425) Show / Hide 
Range on Protein: 91-392
Range on HMM: 1-425/425
Sequence Identity: 19% (91 aa)

KIGSGSFGKIVRVTRSYYED------DGVTISKSIYVFKILKKSQKI------------IQITDENGQSQL--KKELDLLYQELEIYKY-------LNNV
..|.|||||  ....              |  .  .  ||..|..              |... . ....    | .. ...|.|| |        |.  
TLGRGSFGKVKLCIHKNTTGKERVHHI-YTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHP

NICKLYQIID---------APY---------EQTIYLVM---QYCDLG---------------------QILNLDEKDQKYYPNTKIDQFIEQTYNISEQ
||.|||....           |         .. .|.||    ||. |                     |                              
NIIKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQ-----------------------------F

DQYKKR----EKFAKVIFKQVSQGLKYLHDKKIVNRDIKIDNILGKSIECDKG------------ENFKIIDFSTAVKLKSHH-----------------
|   .|    |. |. .|.|. ....|.|...|| ||.| .|||  . . |.              | |||||  | |... .                 
DIV-ERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQW

------QKVFGQAGTPAYQS-PEVCTKSN-----------DGYDGKAADIWSLGVTIYCYVNLSLPFLNQP------------DPQKLFNSILNDPIQF-
      ||   . |||.| . |||  ..              |.|...|.||.||  |  .   .||                ....||  |..   .| 
TTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFP

------------------------QTHNSALFLDLINNMCRKNPKERLKIDQVLNHQWF
                        . . |.   |||..| ...|..|..|.|.|||.|.
PPYFSPISCNYGPEWWDDISDEFHH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 8975.AA Pkinase 86-392 23 1.4e-46 165.79 Pfam 1-293 (293) Show / Hide 
Range on Protein: 86-392
Range on HMM: 1-293/293
Sequence Identity: 23% (82 aa)

YELLDKIGSGSFGKIVRVTRSYYEDDGVTISKSIYVFKILKKSQKIIQI------TDENGQSQLKKELDLLYQELEIYKYLNNVNICKLYQIIDAPYEQT
|... ||||||||.  . ..  ...        |.. ||.||. .  .       .                .|..| | ||  ||..|| .     .. 
YHIGRKIGSGSFGCVYKCHHKGTGK--------IVAVKIIKKRHEKSWKDQTHRRL----------------SEIQIMKRLNHPNIVRLYDWFED--KDH

IYLVMQYCDLG----QILNLDEKDQKYYPNTKIDQFIEQTYNISEQDQYKKREKF------AKVIFKQVSQGLKYLHDKKIVNRDIKIDNILGKSIECDK
||.|| ||. |        . .                           ... .|      .| ...|. .||.|.|...|. ||.| .|||   |  ..
IYMVMEYCEGGLYVMDLFDYIST--------------------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENIL---ID-NN

GEN---FKIIDFSTAVKL-KSHHQKVFGQAGTPAYQSPEVCTKSN-DGYDGKAADIWSLGVTIYCYVNLSLPFLNQ-----PDPQKLFNSILNDPIQFQT
|..   .||.||  | ..   . .   . .||| | .|||    . . |.|...|.||.|...|. ..  .|| ..      |...... |.  |. |. 
GHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV---IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDW

HNS---------------------ALFLDLINNMCRKNPKERLKIDQVLNHQWF
 ..                       ..|.|.....|.||.|. ..|.|.| ||
PWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 8975.AA Ciliate-E2 86-392 22 1e-45 154.87 In-house 1-365 (365) Show / Hide 
Range on Protein: 86-392
Range on HMM: 1-365/365
Sequence Identity: 22% (92 aa)

YELLDKIGSGSFGKIVRVTRSYYEDDGVTISKSIYVFKI--------LKKSQKIIQITDENGQSQLKKELDLLY---------QELEIYKYLNNVNICKL
|... |||.|.||.. ....  ....   . | |. .|.         |.... . |  .|.  |.|.|....          .|..| . ||. ||.|.
YKFIKKIGQGNFGSVYKCKV--WKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKM

YQIIDAPYEQTIYLVMQYCDLGQILN-LDEKDQKYYPNTKIDQFIEQTYNISEQDQYKKREKFAKVIFKQVSQ---------------GLKYLHDKK-IV
|       ...||||| ||. |  .  . ....|   . .            . |  .  || .| |.||. |               .|.||| |. |.
YECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE------------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNII

NRDIKIDNILGKSIECDKGENFKIIDFSTA----------------VKLKSHH----------------QKVFGQAGTPAYQSPEVCTKSNDG------Y
 |||| .|||            ||||| ..                 ...  .                . .. ..||| |..||.  . ...      .
HRDIKPENILF----------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKG

DGKAADIWSLGVTIYCYVNLSLPFLNQPDPQKLFNSILNDPIQFQ------------------THNSALFLDLINN----MCRKNPKERLK-IDQVLNHQ
 ....|||||||..|. .   .||         .. |.. .|.|.                   . |    |||..    |  |.|..|.  ..|.|||.
YDYKCDIWSLGVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHP

WF
||
WF
Kinase 8975.AA Ciliate-E2-Unclassified 86-392 25 8.6e-40 135.71 In-house 1-352 (352) Show / Hide 
Range on Protein: 86-392
Range on HMM: 1-352/352
Sequence Identity: 25% (100 aa)

YELLDKIGSGSFGKIVRVTRSYYEDDGVTISKSIYVFKILKKSQKIIQITDENGQSQLKKELDLLYQ-----------ELE-IYKYLNNVNICKLYQIID
|... .||.|.|||. .. ..          | .|. |..||.|.. |   .| . ... |.. . .           ..  | . ... .| |.. .  
YKIIKQIGQGGFGKVYKCQHK--------KQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQ

APYEQTIYLVMQYC---DLGQILNLDEK--DQKYYPNTKIDQFIEQTYNISEQD----QYKKR---EKFAK-----VIFKQVSQGLKYLHDKK-IVNRDI
   .|.||.||.||   || |...  .|    |                   .|    .....   |. ||      .|.|. |||.||| |. |. |||
--DKQNIYIVMEYCEGGDLWQYIKKRKKQKQ-K------------------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDI

KIDNILGKSIECDKGE---NFKIIDFSTAVKLKSH---------------HQKVFGQAGTPAYQ----SPEVCTKSNDGYDG-KAADIWSLGVTIYCYVN
| .|||      |..    . |||||. . |...                .|.   ..||| |.    .|||  . | .    ...||||||| .|. . 
KPENIL-----FDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLF

LSLPFL-NQPDPQK--------------LFNSILNDPIQFQT--------HNSALFLDLIN----NMCRKNPKERLKIDQVLNHQWF
  .||  |. . ..              |.. |.. .|||.         | |    |.||     |  |||..|. ..|.|||.||
GYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 8975.AA CAMKL 86-392 27 7.5e-39 121.52 In-house 1-297 (297) Show / Hide 
Range on Protein: 86-392
Range on HMM: 1-297/297
Sequence Identity: 27% (94 aa)

YELLDKIGSGSFGKIVRVTRSYYEDDGVTISKSIYVFKILKKSQKI-IQITDEN--GQSQLKKELDLLYQELEIYKYLN---NVNICKLYQIIDAPYE--
|.... .| |||||    |   .        .  .  ||..|. .  ..... |  || . .. .  ...| .| | ||     ||.|||..|. |    
YRIGKTLGKGSFGKVKLATHIRTT-------GEKVAIKIIDKKKIWNDPWMKKNKCGQKH-ESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDI

--QTIYLVMQYCDLGQ------ILNLDEKDQKYYPNTKIDQFIEQTYNISEQDQYKKREKFAKVIFKQVSQGLKYLHDKKIVNRDIKIDNILGKSIECDK
  . ||||| ||. |       | .  ..                          .  |. |. .|.|.  ...|.|...|| |||| .|||   . ...
ETKKIYLVMEYCSGGEMDLFDYIVKHGHRR------------------------GRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENIL---LDENG

GENFKIIDFSTAVKLKSH----HQKVFGQAGTPAYQSPEVCTKSNDGYDGKAADIWSLGVTIYCYVNLSLPFLNQP-------DPQKLFNSILNDPIQFQ
 .| |||||  . . . .     ||   . |.|.|..||.. . |. |||...||||.||. |  |   ||| ...       .  .|.. |  .  .. 
NNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP

--THNSALFLDLINNMCRKNPKERLKIDQVLNHQWF
   | |    |||  |  .||..| .|.|..|| |.
IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 8975.AA STE 225-392 24 1.8e-29 101.27 In-house 140-359 (359) Show / Hide 
Range on Protein: 225-392
Range on HMM: 140-359/359
Sequence Identity: 24% (56 aa)

KKR-------EKFAKVIFKQVSQG-LKYLHDKKIVNRDIKIDNILGKSIECDKGENFKIIDFSTAVKLKSH----------------HQKVFGQAGTPAY
..|       |.  ..| .|. .| |.|||...|. |||| .|||            |..|| .. .| ..                 ||    .||| .
HNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-W

QSPEVCTKS----NDGYDGKAADIWSLGVTIYCYVNLSLPFLNQPDPQKLFNSILN---------------DPIQFQT-------------------HNS
 .||| ..     ..||| | .|||||| ||   ..   |. . .... .|. . |               .| ....                   . |
MAPEVIQQNGQGRDKGYDTK-CDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWS

ALFLDLINNMCRKNPKERLKIDQVLN--HQWF
  | | ||. ..|.|..| . .| |.  | ..
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 8975.AA Meta 295-392 36 7.7e-24 65.67 In-house 186-287 (287) Show / Hide 
Range on Protein: 295-392
Range on HMM: 186-287/287
Sequence Identity: 36% (37 aa)

AGTPAYQSPEVCTKSNDG-YDGKAADIWSLGVTIYCYVNLSLPFLNQPDP-QKLFNSILNDPIQFQT--HNSALFLDLINNMCRKNPKERLKIDQVLNHQ
|||||   || |. .    | |.|.|.|..||| || |    ||. . .    |.. | |.|. |      |.   |.|  |  |||..|. | ..  | 
AGTPAFMAPEACSEEQNHFYCGRALDVWAMGVTLYCFVFGQCPFIDKTNYIMCLHDKIKNHPVMFPEQPEISEDLKDCIKRMLDKNPEHRIMIPEIKTHP

WF
| 
WV
Kinase 8975.AA QIK 228-392 32 1.5e-23 84.58 In-house 117-272 (272) Show / Hide 
Range on Protein: 228-392
Range on HMM: 117-272/272
Sequence Identity: 32% (53 aa)

EKFAKVIFKQVSQGLKYLHDKKIVNRDIKIDNILGKSIECDKGENFKIIDFSTAVKLKSHHQKVFGQAGTPAYQSPEVCTKSNDGYDGKAADIWSLGVTI
|. |. .|.|.  . .|.|...|| ||.|  |||      |.  | ||.||     .    |      |.|.|  ||.    .  |||  .||||.||  
ENEARRWFWQICSAVHYCHKRNIVHRDLKAENIL-----LDNNMNIKIADFGFS-NWFKQGQLLMTWCGSPPYAAPEMFEGKE--YDGPKVDIWSMGVVL

YCYVNLSLPFLNQPDPQKLFNSILNDPIQFQTHNSALFLDLINNMCRKNPKERLKIDQVLNHQWF
|  |  .||| .. . |.| ...|    .     |    .|| .|   .|. |. |.|...|.| 
YVLVCGALPFDGKTL-QNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 8975.AA MARK 296-392 36 1.2e-15 47.73 In-house 167-262 (262) Show / Hide 
Range on Protein: 296-392
Range on HMM: 167-262/262
Sequence Identity: 36% (36 aa)

GTPAYQSPEVCTKSNDGYDGKAADIWSLGVTIYCYVNLSLPFLNQP-DPQKLFNSILNDPIQFQTHNSALFLDLINNMCRKNPKERLKIDQVLNHQWF
|||.| .||.  |    |||...|||||||  |  |  ..|| ..  |  .|.  ||.   .. .| |.   .||. .   ||.|| .|.....| |.
GTPPYMAPEIFLK--KPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 8975.AA Meta 86-193 29 1.9e-11 29.23 In-house 1-112 (287) Show / Hide 
Range on Protein: 86-193
Range on HMM: 1-112/287
Sequence Identity: 29% (36 aa)

YELLDKIGSGSFGKIVRVTRSYYEDDGVTISKSIYVFKILKKSQKIIQITDENGQ-------------SQLKKELDLLYQELEIYKYLNNVNICKLYQII
| | ..|| ||.| .|.    | |.|     .  |  ||| |  | .  .   ..             .|..  ||. |||  | | |. .|. ||. ..
YRLMEEIGKGSYG-VVKLA--YNEED-----HHHYAMKILSK-KKLLKQYGFMRRPPPRGNKPNQGGCIQPRNPLDRVYQEIAILKKLDHPNVVKLVEVL

DAPYEQTIYLVMQYCDLGQIL
| | |  .|.|. |   | ..
DDPNEDYLYMVFEYVEKGPVM
Kinase 8975.AA MARK 231-278 47 3.5e-10 29.65 In-house 106-150 (262) Show / Hide 
Range on Protein: 231-278
Range on HMM: 106-150/262
Sequence Identity: 47% (23 aa)

AKVIFKQVSQGLKYLHDKKIVNRDIKIDNILGKSIECDKGENFKIIDF
|..||.|.  ...|.|.| || |||| .|||   | ...  | |||||
ARRIFRQIVSAVNYCHSKNIVHRDIKPENIL---IDENGNHNIKIIDF
Kinase 8975.AA TyrKc 86-392 16 1.3e-09 -67.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 86-392
Range on HMM: 1-280/280
Sequence Identity: 16% (58 aa)

YELLDKIGSGSFGKIVRVTRSYYEDDGVTISKSIYVF-KILKKSQKIIQITDENGQSQLKKELDLLYQELEIYKYL--NNVNICKLYQIIDAP-----YE
 .|..|.|.| ||.... | .            | |  | ||..                  .  ...|..| . |  .. || .|| ..  .     | 
ITLGKKLGEGAFGEVYKGTWK------------IQVAVKMLKEDA-----------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYI

QTIYLVMQYCDLGQILNLDEKDQKYYPNTKIDQFIEQTYNISEQDQYKKREKFAKVIFKQVSQGLKYLHDKKIVNRDIKIDNILGKSIECDKGENFKIID
. ...|| |...|  ..   | ..                .. .|  .        .  |...|  |||.|... ||.   |.|   .  ..    || |
EPLMIVMEYMPHGDLKDYLRKHRPK---------------LCMKDLLS--------FCWQIACGMEYLHSKNCIHRDLAARNCL---VGENH--TVKISD

FSTAVKLKSH-----HQKVFGQA---GTP-----AYQSPEVCTKSNDGYDGKAADIWSLGVTIYCYVNL-SLPFLNQ----PDPQKLFNSILNDPIQFQT
|  . .....      ...  ..   |.         .||.    |.|    . |.|| ||...    .   |  ..     ..| ... . .     | 
FGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQP

HN---------SALFLDLINNMCRKNPKERLKIDQVLNHQWF
.|         ..   ...   .. .|..|    ..  |. |
PNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 8975.AA STE 86-190 20 7.2e-08 24.0 In-house 1-122 (359) Show / Hide 
Range on Protein: 86-190
Range on HMM: 1-122/359
Sequence Identity: 20% (26 aa)

YELLDKIGSGSFGKIVRVTRSY---YEDDGVTI-----SKSIYVFKILK---KSQKIIQITDENGQSQ----LKKELDLLYQELEIYKYLN--NVNICKL
.|...|||.|.||. ..  .     .. .   .     .. |.  |...   ...|. . . || | .     ..|.. . .|..| | .|    || | 
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKD-ENQ-EN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKY

YQIID-----APYEQTIYLVMQYCDLG
|            .......| |.| |
YGCYFKEGHNHKNDDELWICMEYMDGG
Kinase 8975.AA Meta 228-261 47 2e-06 14.56 In-house 122-155 (287) Show / Hide 
Range on Protein: 228-261
Range on HMM: 122-155/287
Sequence Identity: 47% (16 aa)

EKFAKVIFKQVSQGLKYLHDKKIVNRDIKIDNIL
|. |  .|. . .|| |||  ||. ||||  | |
EDQAWSYFRDIVCGLEYLHYQKIIHRDIKPSNLL
Kinase 8975.AA MARK 153-187 47 0.000482 9.3 In-house 49-84 (262) Show / Hide 
Range on Protein: 153-187
Range on HMM: 49-84/262
Sequence Identity: 47% (17 aa)

ELEIYKYLNNVNICKLYQIIDAPYEQT-IYLVMQYC
|.|| | |.  || ||...|. . ||. |||.| |.
EIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYA
Kinase 8975.AA QIK 144-192 32 0.000719 11.34 In-house 39-85 (272) Show / Hide 
Range on Protein: 144-192
Range on HMM: 39-85/272
Sequence Identity: 32% (16 aa)

KKELDLLYQELEIYKYLNNVNICKLYQIIDAPYEQTIYLVMQYCDLGQI
...|  .| | .| | |.  .| ||||..    .. .|.|. ||  | .
EENLQKCYREVQIMKMLYHPHIIKLYQVMET--DDMMYIVTEYCSNGEM
Kinase 8975.AA MARK 86-99 50 0.002131 7.16 In-house 1-14 (262) Show / Hide 
Range on Protein: 86-99
Range on HMM: 1-14/262
Sequence Identity: 50% (7 aa)

YELLDKIGSGSFGK
|..|  || ||..|
YKMLKTIGHGSYAK