Gene 8976 (Tetrahymena)

8976

Species: Tetrahymena
Alias: 3721.m00056, 75.m00174, PreTt08976, 365, TTHERM_00564380, 8976
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: CAMKK
Subfamily: CAMKK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
8976.AA Protein None 410 None Fasta, JSON
8976.kin_dom Protein Kinase Domain None 317 None Fasta, JSON
8976.NA RNA None 1233 None Fasta, JSON

Protein domain

Protein domains of 8976.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 8976.AA CAMKK-Unclassified 91-407 40 8.10000000001e-194 637.24 In-house 1-392 (392) Show / Hide 
Range on Protein: 91-407
Range on HMM: 1-392/392
Sequence Identity: 40% (160 aa)

YEFLEKLGQGSFGKVKKVERRYLDEDGVTIFK-----KSQLEYERVFAYNSD-GESFMTNRLHLIQEEINIYKNLNHPNICKLFQIIDDETDEKLYL--I
||||.|||.|||||||...||| ..|||....     |.|......|.||.. ....|.|||||.|.||.|.|.|.|||||||...|||....|.|.  .
YEFLDKLGRGSFGKVKLATRRYTTDDGVQKQFAIKVFKKQKLKKKKFIYNDNAFTMKMKNRLHLVQQEIAIMKKLWHPNICKLYEVIDDPDNDKIYMGQV

LEYCDMGQLMVWNEDNQYYDPND-------------KLDQFICQQYGINGILLRIKSIIICLFSNQILEQDQYKRREQQAKIIFQQIAKGVQYLHKRN--
.|||.|||.|.|....|.|.|||             |.|||.||.|..||.|.......||||||||||...||..||..|..|.|..||.||.|..|  
MEYCQMGQIMSWDYWKQDYQPNDGEIEYFFQTQTEYKPDQFCCQYYNQNGKLHNRQNQKICLFSNQILEMKPYKMHEQYLKKYFRQCCKGLQYMHNFNQA

-------------------IINRDIKIDNILCKSDEN--GEHFKLADYTTAKKLTHQQQK-LKDCAGTSGFRCPEQQFNLEQGYDGKA------------
                   ||.||||..|||.....|  |||||.||........|.||| ||..|||..|..||.... ...||...            
CSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKENFKYDYNDYSFLPGTFNPLR

-------------CDIWSLGISIITYVNHKIPFWAESNL----QTDIAAK-NNPIQYEKHNSDLLKDLIESMCKKSEVDRINIDQVLAHPFF
             .||||||......|.|..|||....     |...... |.|.||..|.|...||||..||.|....||.|||.|.||.|
KTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCDKNPKKRITIDQMLVHPWF
Kinase 8976.AA CAMKK 91-407 29 1.7e-160 513.51 In-house 1-396 (396) Show / Hide 
Range on Protein: 91-407
Range on HMM: 1-396/396
Sequence Identity: 29% (120 aa)

YEFLEKLGQGSFGKVKKVERRYLD--EDGVTIFKK-----SQLEYERVFAYNSD--------GESFMTNRLHLIQEEINIYKNLNHPNICKLFQIIDDET
||.....|||.|||||.. ..|..  .....||.|      .............        ||..|.|.......||.|.|..|||||.||...|||..
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

DEKLYLI-LEYCDMGQLMVWNEDNQYYDPND---------------KLDQFICQQYGINGILLRIKSIIICLFSNQILEQDQYKRREQQAKIIFQQIAKG
..|.|.. .|||..||.| |....|.|.||.               |.......|..|...            .||...||||...|..|. .|....||
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEF------------INQVVKQDQYFIHEDYAWKYFRDCIKG

VQYLH-KRN-------------------IINRDIKIDNILCKSDENGEHFKLADYTTAKKLTHQQQKLKD-----------CAGTSGFRCPEQQFNLEQG
..||| ...                   ||.||||..|||......|||.|.||.........|.|.|..           .|||  |..||.... .|.
LEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQK

-------------YDGKACDIWSLGISIITYVNHKIPFWAESNLQTDI---AAKNNPIQYEK-------------HNSDLLKDLIESMCKKSEVDRINID
             |.|||.|||.||......|..|.|||.....|..    . ||.||....             ..|..|||||. |..| . .||.|.
ENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIP

QVLAHPFF
|.. ||..
QIKVHPWV
Kinase 8976.AA S_TKc 91-407 22 3.1e-41 144.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 91-407
Range on HMM: 1-231/231
Sequence Identity: 22% (74 aa)

YEFLEKLGQGSFGKVKKVERRYLDEDGVTIFKKSQLEYERVFAYNSDGESFMTNRLHLIQEEINIYKNLNHPNICKLFQIIDDETDEKLYLILEYCDM--
||.|.|.|.|.||||.|.  .    . .   |.                         |. ||.| |. .||||.||. ...|   ..||...||||   
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK---------------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDL

GQLMVWNEDNQYYDPNDKLDQFICQQYGINGILLRIKSIIICLFSNQILEQDQYK-----RREQQAKIIFQQIAKGVQYLHKRNIINRDIKIDNILCKSD
| |.                                          ..... ...       | .|. ...||.....|.|...|| ||.| .|||. . 
GDLF------------------------------------------DYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-

ENGEHFKLADYTTAKKLTHQQQKLKDCAGTSGFRCPEQQFNLEQGYDGKACDIWSLGISIITYVNHKIPFWAESNLQTDIAAKNNPIQYEKHNSDLLKDL
    | |..|   |..|       . . ||  .. ||       ||....||.||.|. ..  .  . ||. . ..  ..             |. .||.
----HIKICDFGLARQL-------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----------SPEAKDF

IESMCKKSEVDRINIDQVLA-------HPFF
|. ...|   .|. . ..|.       ||.|
IRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 8976.AA Pkinase 246-407 22 2.9e-34 122.22 Pfam 107-293 (293) Show / Hide 
Range on Protein: 246-407
Range on HMM: 107-293/293
Sequence Identity: 22% (43 aa)

EQQAKIIFQQIAKGVQYLHKRNIINRDIKIDNILCK-SDENGEHFKLADYTTAKKL-THQQQKLKDCAGTSGFRCPEQQFNLE-QGYDGKACDIWSLGIS
|...| .. ||..|..|.|...|| ||.| .|||..  .......|..|   ||.. .  .. ... .||.... ||    .  . |.|...|.||.|. 
EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV---IRGGQYYGPKVDMWSCGCI

IITYVNHKIPFWAE------SNLQTDIAAKNNPIQYEKHNS---------------------DLLKDLIESMCKKSEVDRINIDQVLAHPFF
..  .. . ||. .      . .|     .  |. ..  ..                     . .||.|.....|   .|....|.| ||.|
LYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 8976.AA CAMK 246-407 21 5.4e-34 106.39 In-house 178-425 (425) Show / Hide 
Range on Protein: 246-407
Range on HMM: 178-425/425
Sequence Identity: 21% (54 aa)

EQQAKIIFQQIAKGVQYLHKRNIINRDIKIDNILCKSDENGE--------------HFKLADYTTAKKLTH-----------------------QQQKLK
|..|. .|.||. .|.|.|..||. ||.| .|||. ......                |..|   |.|...                       . ||.|
EREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMK

DCAGTSGFRC-PEQQFN-----------LEQGYDGKACDIWSLGISIITYVNHKIPFWAE---------------SNLQTDIA-AKNN-PIQY-------
.. || .. . ||                |. |.|..||.||.|.   . .  . ||...               ..|   |  .| . |  |       
TFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCN

--------------EKHNSDLLKDLIESMCKKSEVDRINIDQVLAHPFF
              . . |.  |||| .| ..   .|..|.|.|.||..
YGPEWWDDISDEFHH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 8976.AA Ciliate-E2 217-407 23 3.8e-29 97.18 In-house 116-365 (365) Show / Hide 
Range on Protein: 217-407
Range on HMM: 116-365/365
Sequence Identity: 23% (63 aa)

INGILLRIKSIIICLFSNQILEQDQYKRREQQAKIIFQQIAK---------------GVQYLHKRN-IINRDIKIDNILCKSDENGEHFKLADYTTAKKL
..|  |.   .. ....|...|.|  .  |...| |..||..               ...|||..| || |||| .|||          |..|  ..||.
CQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------IKIIDFGLSKKY

THQ-------------------------------QQKLKDCAGTSGFRCPEQQFNLE------QGYDGKACDIWSLGISIITY--VNHKIPFWAESNLQT
. .                               |.  . ..|| |. .||   . .      | . ...|||||||  .| |  .  | ||        
DDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG--VILYEMLFGKPPF--------

DIAAKNNPIQYE------------------KHNSDLLKDLIES----MCKKSEVDRIN-IDQVLAHPFF
 .  |...|..                   |. |.  ||||      | .| .  ||. ..|.| ||.|
QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 8976.AA Ciliate-E2-Unclassified 148-407 23 2.8e-27 91.71 In-house 49-352 (352) Show / Hide 
Range on Protein: 148-407
Range on HMM: 49-352/352
Sequence Identity: 23% (79 aa)

LIQEEINIYKN----------------LNHPNICKLFQIIDDETDEKLYLILEYCDMGQLMVWNEDN----QYYDPNDKLDQFICQQYGINGILLRIKSI
...|.. . ..                ||||.....  .  .......|...|||. | |. . ...    |      |                     
IMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQ------K---------------------

IICLFSNQILEQDQYKRR---EQQAK-----IIFQQIAKGVQYLHKRN-IINRDIKIDNILCKSDENGEHFKLADYTTAKKLTHQ---------------
       . | .....|.   |||||      .| || .| .|||. | || |||| .||| ... .  . |..|.  .||.  .               
------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWK

QQKLKDCAGTSGFR----CPEQQFNLEQ-GYDG---KACDIWSLGISIITYVNHKIPFWAESNLQ----------------TDIAAKNNPIQYEK-----
||......|| ..      ||    |.. .||.   ..|||||||. .   .  . || ...  |                     |...||. |     
QQMMWTFCGTPNYMPQYTAPEV---LQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQ

---HNSDLLKDLIE----SMCKKSEVDRINIDQVLAHPFF
   | |.  ||.|.    .| ||    ||...|.| ||.|
IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 8976.AA ULK 235-407 27 3.6e-26 88.42 In-house 109-329 (329) Show / Hide 
Range on Protein: 235-407
Range on HMM: 109-329/329
Sequence Identity: 27% (61 aa)

QILEQDQY---------KRREQQAKIIFQQIAKGVQYLHKRNIINRDIKIDNILCKSDENGE---------HFKLADYTTAKKLTHQ---QQKLKDCA--
|.......         .  ||.|...|.||. | ..|||.||| |||| .||| . .  .          ..|.||   ||...     || .. |   
QYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNE

----GTSGFRCPEQQFNL--EQGYDGKACDIWSLGISIITYVNHKIPF--WAESNLQTDIAAKN-------------NPIQYE-----KHNSDLLKDLIE
    ||  . .|.   ..  .. |. . |||||||. .   .  | ||  |  . ..  |  |.             .|.|..     .. |. .|||| 
KRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIR

SMCKKSEVDRINIDQVLAHPFF
 | .. | |||.......||.|
RMLQYDEKDRISWEELFNHPWF
Kinase 8976.AA STE 245-407 25 1.2e-22 76.86 In-house 142-359 (359) Show / Hide 
Range on Protein: 245-407
Range on HMM: 142-359/359
Sequence Identity: 25% (59 aa)

R-------EQQAKIIFQQIAKG-VQYLHKRNIINRDIKIDNILCKSDENGEHFKLADYTTAKKLTH----------------QQQKLKDCAGTSGFRCPE
|       |.| ..| .|| ||  .|||. .|| |||| .|||          ||.|  ....||.                .||| . ..||  .  ||
RQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPE

QQFNLE----QGYDGKACDIWSLGISIITYVNHKIPF---WAESNLQTDIAAK-------------NNPIQYEK-------------------HNSDLLK
   . .    .||| | |||||||. ||  .. | |.      ...   .  .             ..| . .                    . |. .|
VIQQNGQGRDKGYDTK-CDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFK

DLIESMCKKSEVDRINIDQVLA--HPFF
| |.  ..|   .| . .| |   |||.
DFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 8976.AA ULK 235-341 29 3.9e-18 60.99 In-house 106-240 (324) Show / Hide 
Range on Protein: 235-341
Range on HMM: 106-240/324
Sequence Identity: 29% (40 aa)

QILEQDQY--------KRREQQAKIIFQQIAKGVQYLHKRNIINRDIKIDNILCKSDENGE---------HFKLADYTTAKKLTH---QQQKLKDCA---
|.......        .  ||.|...|.||. | ..|||.||| |||| .||| . .  .          ..|.||   ||..     .||... |    
QYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEK

---GTSGFRCPEQQFNL--EQGYDGKACDIWSLGI
   ||  . .|. . ..  .. |. . |||||||.
RIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGC
Kinase 8976.AA CAMK 96-191 22 2.8e-17 51.57 In-house 1-147 (425) Show / Hide 
Range on Protein: 96-191
Range on HMM: 1-147/425
Sequence Identity: 22% (33 aa)

KLGQGSFGKVKKVERR-YL-DED-----------GVTIFKKSQLE----------YERVFAYNSDGESFM--TNRLHLIQEEINIYKN-------LNHPN
.||.|||||||.....    .|.            . | .|..|           |  ..  . .. ...   . .. .. ||.| |.       |.|||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCY-KIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

ICKLFQIIDDET-----------------DEKLYLIL---EYCDMGQL
|.||.....|..                 |...|...   |||. | |
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGEL
Kinase 8976.AA Ciliate-E2 91-192 26 8.7e-17 54.13 In-house 1-122 (365) Show / Hide 
Range on Protein: 91-192
Range on HMM: 1-122/365
Sequence Identity: 26% (33 aa)

YEFLEKLGQGSFGKVKKVERRYLDEDGVTIFKKSQL-------EYERVFAYNSDGESFMTNRLHLIQEEINIYK----------------NLNHPNICKL
|.|..|.|||.||.|.|....  ...   .... |.       |.  .. |.   .... | .  |  ||.|..                .||||||.|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAM--KIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKM

FQIIDDETDEKLYLILEYCDMGQLM
.    ...|...||..|||. | |.
YECFQEKDDNNIYLVMEYCQGGDLF
Kinase 8976.AA MARK 149-194 44 1.2e-14 44.41 In-house 46-92 (262) Show / Hide 
Range on Protein: 149-194
Range on HMM: 46-92/262
Sequence Identity: 44% (21 aa)

IQEEINIYKNLNHPNICKLFQIIDDETDEK-LYLILEYCDMGQLMVW
.. ||.| | |.|||| |||..|. .| .. .|||.||.  | |. .
VMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDY
Kinase 8976.AA CAMKL 152-192 45 1.3e-14 42.93 In-house 62-111 (297) Show / Hide 
Range on Protein: 152-192
Range on HMM: 62-111/297
Sequence Identity: 45% (23 aa)

EINIYKNLN---HPNICKLFQIIDD-----ETDEKLYLILEYCDMGQ--LM
||.| | ||   ||||.||...|..     || .|.||..|||. |   |.
EIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLVMEYCSGGEMDLF
Kinase 8976.AA STE 91-189 24 2.5e-12 39.93 In-house 1-122 (359) Show / Hide 
Range on Protein: 91-189
Range on HMM: 1-122/359
Sequence Identity: 24% (31 aa)

YEFLEKLGQGSFGKVKKVERRYLD---EDGVT--------IFKKSQLEYERVFAYNSD---GESFM-----TNRLHLIQEEINIYKNLN--HPNICKLFQ
.|..||.|.|.||.| |  ..  .   . | .        |.   |...|.  ... .     . .     .. .  |..||.| |..|  |||| | . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYG

IIDDET-----DEKLYLILEYCDMG
   .|      |..|....||.| |
CYFKEGHNHKNDDELWICMEYMDGG
Kinase 8976.AA CAMKL 246-279 47 4.3e-12 34.75 In-house 126-159 (297) Show / Hide 
Range on Protein: 246-279
Range on HMM: 126-159/297
Sequence Identity: 47% (16 aa)

EQQAKIIFQQIAKGVQYLHKRNIINRDIKIDNIL
| .|. .|.||  .|.|.|...|. |||| .|||
EHEARRYFRQIVSAVNYCHSHGIVHRDIKPENIL
Kinase 8976.AA MARK 246-279 52 5.4e-11 32.35 In-house 103-136 (262) Show / Hide 
Range on Protein: 246-279
Range on HMM: 103-136/262
Sequence Identity: 52% (18 aa)

EQQAKIIFQQIAKGVQYLHKRNIINRDIKIDNIL
|  |. ||.||  .|.|.|..||. |||| .|||
EEEARRIFRQIVSAVNYCHSKNIVHRDIKPENIL
Kinase 8976.AA CAMKL 326-407 26 2.7e-09 25.67 In-house 209-297 (297) Show / Hide 
Range on Protein: 326-407
Range on HMM: 209-297/297
Sequence Identity: 26% (24 aa)

EQGYDGKACDIWSLGISIITYVNHKIPFWAES-------NLQTDIAAKNNPIQYEK---HNSDLLKDLIESMCKKSEVDRINIDQVLAHPFF
.. |||.. ||||.|.   . |  . || ...       |  .    ..    |.    | |  ..||| .| ..   .|..|.|.. ||..
NKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 8976.AA Pkinase 152-192 40 4.5e-09 33.18 Pfam 50-92 (293) Show / Hide 
Range on Protein: 152-192
Range on HMM: 50-92/293
Sequence Identity: 40% (18 aa)

EINIYKNLNHPNICKLFQIIDDETDEKLYLILEYCDMG----QLM
|| | |.||||||..|. .  |  . ..|...|||..|     |.
EIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLF
Kinase 8976.AA TyrKc 91-407 15 1.3e-08 -83.37 SMART 1-280 (280) Show / Hide 
Range on Protein: 91-407
Range on HMM: 1-280/280
Sequence Identity: 15% (56 aa)

YEFLEKLGQGSFGKVKKVERRYLDEDGVTIFKKSQLEYERVFAYNSDGESFMTNRLHLIQEEINIYKNL--NHPNICKLFQIIDDE-----TDEKLYLIL
 ....||| | ||.| | . .      ..   |.  |.                 .  . .|..| ..|  .|||| .|. .. ..      .| |....
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVM

EYCDMGQLMVWNEDNQYYDPNDKLDQFICQQYGINGILLRIKSIIICLFSNQILEQDQYKRREQQAKIIFQQIAKGVQYLHKRNIINRDIKIDNILCKSD
||.. | |     ...                                               ..   .  |||.| .|||..|.| ||.   |.| ...
EYMPHGDLKDYLRKHRPK------------------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGEN

ENGEHFKLADYTTAKKLTHQ-----QQKLKDCAGTSGFR--CP----------EQQFNLEQGYDGKACDIWSLGIS---IITYVNHKIPF-----WAESN
    . | .|   ......       .. .. ....| .   |          .  |.        . |.|| |.    | ||     |         . 
H---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-------TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQE

LQTDIAAKNNPIQYEK-------HNSDLLKDLIESMCKKSEVDRINIDQVLAHPFF
.  .. . . . | .        . .| . ..... ..    || .  ..  | .|
VIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 8976.AA MARK 325-407 26 1.3e-08 24.47 In-house 178-262 (262) Show / Hide 
Range on Protein: 325-407
Range on HMM: 178-262/262
Sequence Identity: 26% (23 aa)

LEQGYDGKACDIWSLGISIITYVNHKIPFW--A--ESNLQTDIAAKNNPIQYEKHNSDLLKDLIESMCKKSEVDRINIDQVLAHPFF
| . |||.. ||||||.   . |  . ||      . .|.  | . . .| .    |. ...|| .. .    .|. |.... ||..
LKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 8976.AA ULK 366-407 40 1.5e-08 26.51 In-house 278-324 (324) Show / Hide 
Range on Protein: 366-407
Range on HMM: 278-324/324
Sequence Identity: 40% (19 aa)

KNNPIQYEKHN-----SDLLKDLIESMCKKSEVDRINIDQVLAHPFF
||.|||. | .     |. .||||  | .. | |||.......||.|
KNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 8976.AA Ciliate-E2-Unclassified 91-111 42 1.5e-07 22.3 In-house 1-21 (352) Show / Hide 
Range on Protein: 91-111
Range on HMM: 1-21/352
Sequence Identity: 42% (9 aa)

YEFLEKLGQGSFGKVKKVERR
|......|||.||||.|....
YKIIKQIGQGGFGKVYKCQHK
Kinase 8976.AA CAMKL 91-106 62 2.9e-07 19.06 In-house 1-16 (297) Show / Hide 
Range on Protein: 91-106
Range on HMM: 1-16/297
Sequence Identity: 62% (10 aa)

YEFLEKLGQGSFGKVK
|.... ||.|||||||
YRIGKTLGKGSFGKVK
Kinase 8976.AA MARK 91-108 44 2e-06 16.96 In-house 1-18 (262) Show / Hide 
Range on Protein: 91-108
Range on HMM: 1-18/262
Sequence Identity: 44% (8 aa)

YEFLEKLGQGSFGKVKKV
|..|  .|.||..|||..
YKMLKTIGHGSYAKVKLA
Kinase 8976.AA ULK 148-189 36 2e-06 18.61 In-house 56-105 (329) Show / Hide 
Range on Protein: 148-189
Range on HMM: 56-105/329
Sequence Identity: 36% (18 aa)

LIQEEINIYKNLN--------HPNICKLFQIIDDETDEKLYLILEYCDMG
|.. || | | |.        ||||.||. .  . ..  .|.|.|||. |
LLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGG
Kinase 8976.AA Pkinase 91-111 42 3.5e-05 19.39 Pfam 1-21 (293) Show / Hide 
Range on Protein: 91-111
Range on HMM: 1-21/293
Sequence Identity: 42% (9 aa)

YEFLEKLGQGSFGKVKKVERR
|....|.|.||||.|.|  ..
YHIGRKIGSGSFGCVYKCHHK
Kinase 8976.AA ULK 148-187 37 4.8e-05 13.9 In-house 56-100 (324) Show / Hide 
Range on Protein: 148-187
Range on HMM: 56-100/324
Sequence Identity: 37% (17 aa)

LIQEEINIYKNLN---HPN--ICKLFQIIDDETDEKLYLILEYCD
|.. ||.| | |.   |||  |.||. .  . ..  .|.|.|||.
LLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN
Kinase 8976.AA ULK 91-107 58 8.3e-05 12.81 In-house 1-17 (329) Show / Hide 
Range on Protein: 91-107
Range on HMM: 1-17/329
Sequence Identity: 58% (10 aa)

YEFLEKLGQGSFGKVKK
|.  ..||.|||||| |
YCLNHCLGKGSFGKVYK
Kinase 8976.AA ULK 91-107 55 0.000121 12.47 In-house 1-18 (324) Show / Hide 
Range on Protein: 91-107
Range on HMM: 1-18/324
Sequence Identity: 55% (10 aa)

YEFLEKLGQGSFG-KVKK
|.  ..||.|||| || |
YCLNHCLGKGSFGVKVYK
Kinase 8976.AA Pkinase_Tyr 91-107 52 0.001887 12.31 Pfam 1-17 (270) Show / Hide 
Range on Protein: 91-107
Range on HMM: 1-17/270
Sequence Identity: 52% (9 aa)

YEFLEKLGQGSFGKVKK
 .|..|||.|.||.|.|
ITFGKKLGEGAFGEVYK
Kinase 8976.AA Pkinase_Tyr 151-189 34 0.037075 7.93 Pfam 52-92 (270) Show / Hide 
Range on Protein: 151-189
Range on HMM: 52-92/270
Sequence Identity: 34% (14 aa)

EEINIYKNL-NHPNICKLFQIIDDETDE-KLYLILEYCDMG
.|..| |.| .|||| .|  .. |. .  ..|...||.  |
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG
Kinase 8976.AA Pkinase_Tyr 254-269 56 0.331009 4.71 Pfam 118-133 (270) Show / Hide 
Range on Protein: 254-269
Range on HMM: 118-133/270
Sequence Identity: 56% (9 aa)

QQIAKGVQYLHKRNII
.||||| .||. .|.|
WQIAKGMEYLESKNCI