Gene 13474 (Tetrahymena)

13474

Species: Tetrahymena
Alias: 13474, 1031, TTHERM_00366550, PreTt13474, 38.m00309
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A8

Sequence

Name Sequence Type Origin Length Description Download
13474.AA Protein None 519 None Fasta, JSON
13474.kin_dom Protein Kinase Domain None 156 None Fasta, JSON
13474.NA RNA None 1560 None Fasta, JSON

Protein domain

Protein domains of 13474.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13474.AA Ciliate-A8 83-241 50 7.1e-83 281.63 In-house 1-151 (151) Show / Hide 
Range on Protein: 83-241
Range on HMM: 1-151/151
Sequence Identity: 50% (81 aa)

YVYVKDIINNRFSLVVQAQSLIDQNIVAIEILYN-NQIKKINHKKLEKCVKILENLADEKYILQFIQSIQDLEYGNVAIVTQNYESNLINRLFLKQQKCL
|.|.|......||.||||.|...|..|||.|... ||..|||.|..|||.........||||||.|..|||.|.|..||||..........         
YKYQKVLEKGDFSYVVQAYSINHQCQVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCDCFDFYK---------

KYNLENLASILE--NNNLTMSQIYALTYQLLKGILLFQEKGIVIKDIQPQNILYSSSKNQFL
  ..||||||||  .|..|..||.||||||||..|.||||||...||.|||||||.|||||.
--KKENLASILENNLNKFTFEQIVALTYQLLKCLLVFQEKGIIHCDIKPQNILYSWSKNQFI
Kinase 13474.AA Ciliate-E1 89-264 23 4.3e-16 49.23 In-house 1-169 (202) Show / Hide 
Range on Protein: 89-264
Range on HMM: 1-169/202
Sequence Identity: 23% (42 aa)

IINNRFSLVVQAQSLIDQ-NIVAIEILYNNQI-KKINHKKLEKCVK-ILENLADEKYILQFIQSIQDLEYGNVAIVTQNYESNLINRLFLKQQKCLKYNL
| |. ||.|..| .  .. | ||. |   ... ....  .. |. . |.. .  |.||.|.|. |.. .. . .|...... .| . |. .     .  |
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNH-----N-RL

ENLASILE--NNNLTMSQIYALTYQLLKGILLFQEKGIVIKDIQPQNILYSSSKNQFLLTLKKKLEVSITLSYRQDQTVQY
  .  ...  .|..|  |. ....||..|.  .. ..| . || |||||.... ......   .. .| .| . |.|..||
-EYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYC---DFGISKFLKNNQNQQCQY
Kinase 13474.AA GSK 205-237 36 9e-06 12.93 In-house 121-153 (328) Show / Hide 
Range on Protein: 205-237
Range on HMM: 121-153/328
Sequence Identity: 36% (12 aa)

LTYQLLKGILLFQEKGIVIKDIQPQNILYSSSK
..||...|.   ...||.  || |||||.  ..
YMYQMFRGLAYLHSHGICHRDIKPQNILVDPDT
Kinase 13474.AA S_TKc 83-336 13 1.9e-05 -97.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 83-336
Range on HMM: 1-231/231
Sequence Identity: 13% (40 aa)

YVYVKDIINNRFSLVVQAQSLIDQNIVAIEILYNNQIKKINHKKLEKCVKILENLADEKYILQFIQSIQDLEYGNVAIVTQNYESNLINRLFLKQQKCLK
|  .. |    |. | ...   .. |||| |.          ..... ..||..  . ..| ... ..||   ... .|.                 .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVME----------------YCD

YNLENLASILENNN-------LTMSQIYALTYQLLKGILLFQEKGIVIKDIQPQNILYSSSKNQFLLTLK-------KKLEVSITLSYRQDQTVQY----
 .| .| .......       ..  ..  ..||.....    ..||.  |. |.||| ..       ..|       ..|       . .  |  |    
GDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-------TTFCGTPWYMAPE

-----------------LWVIIL-EALLQRKIQGMEYIKLKSQSLIEVIPDIQSQKNHEFVTNILCRMLDPDRNKRYQPLILLQ-----QLNKLK
                 |.  .  . . .   | .. .|.                 .|.   .....|. | .||.    .||      .    
VLGYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 13474.AA Ciliate-F2 188-243 25 5.6e-05 14.27 In-house 83-138 (200) Show / Hide 
Range on Protein: 188-243
Range on HMM: 83-138/200
Sequence Identity: 25% (14 aa)

LASILENNNLTMSQIYALTYQLLKGILLFQEKGIVIKDIQPQNILYSSSKNQFLLT
.  .|.   ||  |.|  . |.. |.      |..  ||   |..| . |..|...
IKQQLQSCKLTDNQQYEEIQQFINGLAELENLGLIHGDIKIENMIYNRPKQRFMFD
Kinase 13474.AA Ciliate-A1 179-232 30 5.7e-05 12.8 In-house 82-133 (301) Show / Hide 
Range on Protein: 179-232
Range on HMM: 82-133/301
Sequence Identity: 30% (17 aa)

KCLKYNLENLASILENNN-LTMSQIYALTYQLLKGILLFQEKGIVIKDIQPQNIL
.|.. || |.     .|. .   .|| . ||. .|..   .. |. .|. |||||
YCQYGNLFNY---CYQNDYMKKEEIYEICYQIIEGYADIHDHNILHRDLKPQNIL
Kinase 13474.AA Ciliate-E3 196-242 36 5.7e-05 11.78 In-house 99-145 (202) Show / Hide 
Range on Protein: 196-242
Range on HMM: 99-145/202
Sequence Identity: 36% (17 aa)

NLTMSQIYALTYQLLKGILLFQEKGIVIKDIQPQNILYSSSKNQFLL
|.|   || .  |...|..   || |   || |.||| ....||  .
NKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLII
Kinase 13474.AA CDK-Unclassified 193-232 40 0.000138 10.85 In-house 114-153 (324) Show / Hide 
Range on Protein: 193-232
Range on HMM: 114-153/324
Sequence Identity: 40% (16 aa)

ENNNLTMSQIYALTYQLLKGILLFQEKGIVIKDIQPQNIL
. .|| | ||     |.|.||    ...|  .|| ||||.
NRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIM
Kinase 13474.AA CMGC 187-235 18 0.000507 8.08 In-house 140-219 (513) Show / Hide 
Range on Protein: 187-235
Range on HMM: 140-219/513
Sequence Identity: 18% (15 aa)

NLASILENNN----------LTMSQ------------IYALT------YQLLKGIL--LFQEKG--IVIKDIQPQNILYSS
.|. ...||.          |.  .            |  ..      ||.|.|.       ..  |.  |. |.||| ..
DLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINH