Gene 23520 (Tetrahymena)
23520
Group:
Other
Family:
Ciliate-A9
Sequence
Protein domains of 23520.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 23520.AA | Ciliate-A9 | 17-279 | 36 | 5e-230 | 557.28 | In-house | 1-392 (392) | Show / Hide |
Range on Protein: 17-279
Range on HMM: 1-392/392
Sequence Identity: 36% (142 aa)
FQLSEKLGQGAFGTVYKAIDNT--DEQECAIKILYKSNMSCSL-----IEGRLLQQLDHPHIVKFK---------------------RVGETKHAFVIIM
| . ...|.|||| |....|. |.||.|.|. | .|. . .| . |||.|||.||||| .. |. . | |
FEPIKIIGEGAFGCVIQCRDIQQEDKQEYAVKVIQKNKMKMDCIEFQDQEAKILQQHDHPNIVKFKNIKNINTQKETKQLNYIFQISKFCESDQNIHIVM
ELMKGGTIAQLIKQRKQNEQPFTDDEASTIMKCILSAVDYMHSQNILHRDLKPE----------------------------------------------
|.||.||..||.|.||.|.|.|...|.|.|||||.|||.|||..||.||||||.
EYMKCGTLQQLMKERKKNNQWFNEQEISQIMKCIMSAVMYMHQKNICHRDLKPDRQINKCIQLFISSFIHLFINHHNYCKQQNKQTNKQTNEKINQVKIF
----NILLADPNDLTSVKVADFGLG--------IQYSTEMTYRSFLQQCGTVLFMSPEQLKNQPYSKPVD------------------------------
|||..|.||||.||.|||||. .||.|..||.|..|||||...|.|| . | ||.|||
ILTENILIGDKNDLTQVKIADFGLSKSFVKSQRVQYFTQWTYHSMYQQCGTLIYMAPEFFINKQYSQPVDHAVSMKSRKRLIYLFLQLIILFLNSLKSQN
-------------LWSCGIIMYMILSMGRHPFNYNYEIETKEQYIKIITSCSQKIENWPNCSNLAIDLITRLTNFSPSNRYNAGKSLNHPWI
.|||||||||.|.||.|||...||....|.|.|....|....|.|.||||.|...|...||..|||||||...|.||||
QFILYRQFKQQVDMWSCGIIMYMLLCMGKHPFWCPYEKNDDEDYFKMKIQCNPQWEFWDNCSNNAKNFIQKMTNINPSNRYNAFQCLKHPWI
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| Kinase | 23520.AA | S_TKc | 17-279 | 32 | 4.8e-87 | 296.4 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-231/231 Sequence Identity: 32% (88 aa) FQLSEKLGQGAFGTVYKAIDNTDEQECAIKILYKSNMSCSLIEGRLLQQLDHPHIVKFKRVGETKHAFVIIMELMKG--GTIAQLIKQRKQ--NEQPFTD ... .|.|.||||.|||.... . ...||||. . | ..|.. .||.|||.. | .. . . ..||.. | |. ..||.|. . .||. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE DEASTIMKCILSAVDYMHSQNILHRDLKPENILLADPNDLTSVKVADFGLGIQYSTEMTYRSFLQQCGTVLFMSPEQLKNQPYSK-PVDLWSCGIIMYMI .| .|. |..|..|.||..|.||||||||||| . .|..|||| |. .||| .|.|| | .|.| ..| ||||.|.| -HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM LSMGRHPFNYNYEIETKEQYIKIITSCSQKIENWPNCSNLAIDLITRLTNFSPSNRYNAGKSLN-------HPWI |. |. || . .. .|.| | |.|.| .. .. |..|. | . |. |||. LC-GYPPFP------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 23520.AA | CAMK | 22-279 | 22 | 1.3e-81 | 262.67 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 22-279
Range on HMM: 1-425/425
Sequence Identity: 22% (94 aa)
KLGQGAFGTVYKAIDN-TDE-----------QECAIKILYKS-------------------------------NMSCSLIEGRLLQQ-------LDHPHI
.||.|.||.|...|. | |..||||. |. .. . | ..... ||||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VKFKRVGE------------TKHA--------FVIIM---ELMKGG----TIAQLIKQRKQNE-----------QPFTDDEASTIMKCILSAVDYMHSQN
.|. | | | ....| |.. || . . |...... || .||..... |.|||.|.||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
ILHRDLKPENILLADPNDLTS--------------VKVADFGLGIQYSTEMTYR---------------------SFLQQCGTVLFMS-PEQLKN-----
| ||||||||||| | || .. .|..|||. ... .. . .||| .|. || |.
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
---------QPYSKPVDLWSCGIIMYMILSMGRHPFN--YNYEIE-------TKEQYIKIITSCS-QKIEN-------------WPNCSNL--------A
..|....| ||||.|.|. |. |. ||. .. ||. . .. . |... . .. | . |. .
MQNATDEEKPYYGPKCDMWSCGVILYIMLC-GYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC
IDLITRLTNFSPSNRYNAGKSLNHPWI
.||| .. . |..|... |||||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 23520.AA | Pkinase | 17-279 | 28 | 8.2e-78 | 269.61 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-293/293 Sequence Identity: 28% (86 aa) FQLSEKLGQGAFGTVYKAIDNTDEQECAIKILYKSNMSCSLI-------EGRLLQQLDHPHIVKFKRVGETKHAFVIIMELMKGG----TIAQLIKQRKQ ... .|.|.|.||.|||... .... |.||. |.. ... | .... |.||.||..... |.| ..||.. || . .|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W NEQPF--TDDEASTIMKCILSAVDYMHSQNILHRDLKPENILLADPNDL-TSVKVADFGLGIQYSTEMTYRSFLQQCGTVLFMSPEQLK-NQPYSKPVDL .. .| ...|. .|. ||....|.||..|.||||||||||. . ... ..||..|||| |.. . .. . ||| .|.|| .. .|.|...|| RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM WSCGIIMYMILSMGRHPFNYNY----EIETKEQYIKIITSCSQKIENWPNCS-------------------NLAIDLITRLTNFSPSNRYNAGKSLNHPW ||||.|.| |. || || . . .. | |. | .. . . . || ..|.|... .. |. |..| |.||| WSCGCILYEMLC-GRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW I . F |
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| Kinase | 23520.AA | Ciliate-E2 | 17-279 | 23 | 4.8e-74 | 252.31 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-365/365 Sequence Identity: 23% (91 aa) FQLSEKLGQGAFGTVYKAID-NTDEQE-----------------CAIKILYKSNM-----SCSLIEGRLLQ----------------QLDHPHIVKFKRV . . .|.|||.||.|||. . ....|. ..||| .. .| . | .... ||.||.|.|.. . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC GE--TKHAFVIIMELMKGGTIAQLIKQRKQNE-------QPFTDDEASTIMKCILS---------------AVDYMHSQN-ILHRDLKPENILLADPNDL . ... . ..||. .||. ..||..|... ..||. |...||| ||. |. |.||.| |.|||.||||||. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------ TSVKVADFGLGIQYSTEMTYRS-----------------------------FLQQCGTVLFMSPEQLKNQP---------YSKPVDLWSCGIIMYMILSM .|..|||| .|.... .|. | ..||| .|.|| |.... |.. .|.||.|.|.|. | . --IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML-F GRHPFNYNYEIETKEQYIKIITSCSQKIE----------------NWPNCSNLAIDLITR----LTNFSPSNRYN-AGKSLNHPWI |..|| ...| | .. .| ..|. ..||| . . . |..|.. . . |||||. GKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 23520.AA | CAMKL | 17-279 | 27 | 1.4e-69 | 221.21 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-297/297 Sequence Identity: 27% (83 aa) FQLSEKLGQGAFGTVYKAID-NTDEQECAIKILY--KSNMSCSLI----------------EGRLLQQLD---HPHIVKFKRVGETKHA------FVIIM ... . ||.|.||.| |.. | ... ||||. | .. . | .....|. ||.|.|. | ||. ....| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELMKGGT--IAQLIKQRKQNEQPFTDDEASTIMKCILSAVDYMHSQNILHRDLKPENILLADPNDLTSVKVADFGLGIQYST--EMTYRSFLQQCGTVLF |. || . |.... .... .|| . . |.|||.|.||..| |||.||||||| . .. .|..|||....| . . . .||. . EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY MSPEQLKN--QPYS-KPVDLWSCGIIMYMILSMGRHPFN-YNY---EIETKEQYIKIITSCSQKIENWPNCSNLAIDLITRLTNFSPSNRYNAGKSLNHP |.|| .. .|| ..|| ||||.|.|... |. ||. .| . . . ..| .. .. |. | ..||| .. . |. |... .||| MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVC-GYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP WI | WM |
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| Kinase | 23520.AA | Ciliate-E2-Unclassified | 17-279 | 24 | 1.4e-66 | 227.46 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-352/352 Sequence Identity: 24% (87 aa) FQLSEKLGQGAFGTVYKAIDNTDEQECAIKILYKSNMSCSLIEGR----------------------------LLQQLDHPHIVKFKRVGETKHAFVIIM . . ...|||.||.|||.... . | |.|.. |... ... . .|....||.|||. . ..| . |.| YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM ELMKGGTIAQLIKQRKQNE-------------QPFTDDEAS-----TIMKCILSAVDYMHSQN-ILHRDLKPENILLADPNDLTSVKVADFGL--GIQYS |...||. | ||.||.. . ||. .|. .....||.. .|.|..| |.|||.||||||. . . .|..|||. .|.. EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN TEMT-----------YRSFLQQCGTVLFM----SPEQLKNQPYS----KPVDLWSCGIIMYMILSMGRHPFNYNYEIE-------------TKEQYIKII . . . . ..||| .| .|| |..| |. . .| ||.|.|.| .| .|..||..| ... |..| .|. NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEML-FGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK TS-CSQKIENW----PNCSNLAIDLIT----RLTNFSPSNRYNAGKSLNHPWI .... ..| . |. |.|.|. .. . |..|... . |||||. QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | 23520.AA | CAMK1 | 17-212 | 33 | 1.9e-65 | 189.21 | In-house | 1-210 (276) | Show / Hide |
Range on Protein: 17-212 Range on HMM: 1-210/276 Sequence Identity: 33% (73 aa) FQLSEKLGQGAFGTVYKAIDNT---DEQECAIKILY-KSNMSCS--------LIEGRLLQ---QLDHPHIVKFKRVGETKHAFVIIMELMKGGTIAQLIK ... ...| |||..||.... .... |||.. |..|. . . | .. ..|||.|.||. . |.. | ..|||..|| . | YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV QRKQNEQPFTDDEASTIMKCILSAVDYMHSQNILHRDLKPENILLADPNDLTSVK--VADFGLGIQYSTE--MTYRSFLQQCGTVLFMSPEQLKN---QP ... .| ..|..||| ||||| ||||..| ||||||||.|..|. . .| .||||| ... . . . ..||| .. || |.. .| EKG----NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMK----TACGTPGYVAPEVLECKKDKP YSKPVDLWSCGIIMYMIL |.|..|.||.|.| | .| YDKACDMWSIGVITYILL |
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| Kinase | 23520.AA | CAMK-Unique | 17-279 | 23 | 6.8e-64 | 209.74 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 17-279
Range on HMM: 1-363/363
Sequence Identity: 23% (84 aa)
FQLSEKLGQGAFGTVYKAIDNTDEQECAIKILYK-----SNMSC------------------SLIEGRLLQQLDHPHIVKFKRV----GETKH-------
. . .|.|.|| ||...| . . ..|.|.. | . . | .... .|||.|.|. . ...
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------AFVIIMELMKGGTIAQLIKQR----------------KQNEQPFTD--DEASTIMKCILSAVDYMHSQNILHRDLKPENILLADP-ND----
...|.||. ||. ..| .. |. ...|. ....|| |.|||| |||||.| |||||.|||.. . .|
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
--------LTSVKVADFGLGIQYSTEMTYRSFLQQCGTVLFMSP--------------EQLKNQPYSKPV----DLWSCGIIMYMILSMGRHPFNYNYEI
. .|..|||| .|.. . ||| ..|.| | ...|.|. .. |.||.| |||. |. |..||. . |
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLC-GCPPFDCECED
----ETKEQYIKIITSCSQ---KIENWPN---CSNLAIDLITRLTNFSPSNRYNAGKSLNHPWI
. .. |... . . | |. |.|..... . |. | .| | |.||
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | 23520.AA | Ciliate-E2a | 17-220 | 33 | 5e-59 | 172.39 | In-house | 1-217 (275) | Show / Hide |
Range on Protein: 17-220 Range on HMM: 1-217/275 Sequence Identity: 33% (75 aa) FQLSEKLGQGAFGTVYKAIDNTDEQECAIKILYKSNMSCSL-------IEGRLLQQLDHPHIVKFKRVGETKHAFVIIMELMKGGTIAQLIKQRKQNEQP . . |.|.|.|| ||.| . .. |.|.. | |. . | ...|||||.| |. | |... . ..||. .||. . ||| |.. . YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE FTDDEASTIMKCILS-AVDYMHSQNILHRDLKPENILLA--DPND--LTSVKVADFGLGIQYSTEMT-YRSFLQQCGTVLFMS------PEQLKNQPYSK . |.. ||. .|. .. |||..||.||||||||||. ..|. .. .|..||||. .... |. |.||| .. .| ||.. |.. --IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYM--FQKCGTPGYVAPEVLNNKEVLKHKQYDT PVDLWSCGIIMYMILSMGRHPFN .|.||||.|.| | .|. ||. KCDMWSCGVIFYILL-CGKPPFK |
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| Kinase | 23520.AA | ULK | 17-279 | 27 | 3.9e-58 | 199.44 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-329/329 Sequence Identity: 27% (90 aa) FQLSEKLGQGAFGTVYKAIDNTDE----QECAIKI------LYKSNM------SCSLI-EGRLLQQLD--------HPHIVKFKRVGETKHA--FVIIME ..|...||.|.||.|||.... .. . .|.|. |.|. ..|. | .....|. ||.|||.. . ||.. . |||| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME LMKGGTIAQLIKQR-KQNEQP-----FTDDEASTIMKCILSAVDYMHSQNILHRDLKPENILLADPNDLT---------SVKVADFGLGIQYSTE-MTYR . ||. |.||.. |..|. .. .|| ..| ||.. ..|..|| |||.||.|||. ... | .|.||||.. . . . | . YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ SFLQQC------GTVLFMSPEQLK----NQPYS-KPVDLWSCGIIMYMILSMGRHPFNYNYEIETK-EQYIKIITS--------CSQKIE-----NWPNC .. . || |.|.|. |. ..||. . .|.|| |.|.| .| |. ||. . ... ...| | ..|... | |.. MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML-YGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI SNLAIDLITRLTNFSPSNRYNAGKSLNHPWI |. .||| |. . .. | . .||||. SPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | 23520.AA | ULK | 17-279 | 26 | 4.8e-55 | 189.18 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-324/324 Sequence Identity: 26% (88 aa) FQLSEKLGQGAFG-TVYKAIDNTDE---QECAIKILYKSNMSC------------SLI-EGRLLQQLD---HPH--IVKFKRVGETKHA--FVIIMELMK ..|...||.|.|| .|||.... .. | |.|. |..|. .|. | .....|. ||. |||.. . ||.. . ||||. YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN GGTIAQLIKQRKQ-----NEQPFTDDEASTIMKCILSAVDYMHSQNILHRDLKPENILLADPNDLT---------SVKVADFGLGIQ-YSTEMTYRSFLQ ||. |.||..| ... .. .|| ..| |... ..|..|| |||.||.|||. ... | .|.||||.. . . .| . . GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT QC------GTVLFMSPEQLK----NQPYS-KPVDLWSCGIIMYMILSMGRHPFNYNYEIETKE---QYIK--------IITSCSQKIENW--PNCSNLAI .. || |.|.|. |. ..||. . .|.|| |.|.| .| |. ||. . .... . |. | . |. . |..|. . CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML-YGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK DLITRLTNFSPSNRYNAGKSLNHPWI ||| |. . .. | . .||||. DLIRRMLQYDEKDRISWEEIFNHPWF |
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| Kinase | 23520.AA | Pkinase_Tyr | 17-162 | 28 | 4e-22 | 75.57 | Pfam | 1-157 (270) | Show / Hide |
Range on Protein: 17-162 Range on HMM: 1-157/270 Sequence Identity: 28% (46 aa) FQLSEKLGQGAFGTVYKAIDN----TDEQECAIKILYKSNMSCS-------LIEGRLLQQL-DHPHIVKFKRVGE-TKHA--FVIIMELMKGGTIAQLIK .. .|||.||||.|||.. . .....|.|.| | . . . . | ... || .||.||.. | . |.||.|..| . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR QRKQNEQPFTDDEASTIMKCILSAVDYMHSQNILHRDLKPENILLADPNDLTSVKVADFGL ... ..||.| . . | .. .| .|.|. |||| |.|... .. ||..|||| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NN-VVKICDFGL |
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| Kinase | 23520.AA | TyrKc | 17-274 | 21 | 2.6e-15 | 24.88 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 17-274 Range on HMM: 1-280/280 Sequence Identity: 21% (62 aa) FQLSEKLGQGAFGTVYKAIDNTDEQECAIKILYKSNMSCSLI--EGRLLQQL--DHPHIVKFKRVGETK-------HAFVIIMELMKGGTIAQLIKQRKQ .| .||| ||||.|||.. . ...|.| | .. . | |.. .| .||.||.. | .. . |.||.|..| . .. .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP NEQPFTDDEASTIMKCILSAVDYMHSQNILHRDLKPENILLADPNDLTSVKVADFGLGIQYSTE-------MTYRS----FLQQCGTVLFMSPEQLKNQP . .. .. .. | . .| ||.|. |||| |.|..... ||..|||| . .||. . |.|| .. K---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YSKPVDLWSCGIIMYMILSMGRHPFNY-----NYEIETKEQYIKIITSCSQKI-----ENWPNCSNLAIDLITRLTNFSPSNR---YNAGKSL .. | || |. |. |.. | | .| |. . . . |. ..... .. |..| . . . FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF--VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | 23520.AA | CAMK1 | 245-279 | 41 | 1.5e-09 | 23.88 | In-house | 241-276 (276) | Show / Hide |
Range on Protein: 245-279 Range on HMM: 241-276/276 Sequence Identity: 41% (15 aa) WPNCSNL-AIDLITRLTNFSPSNRYNAGKSLNHPWI | | |. | |.|. . . |..||.. ..|||||| WDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 23520.AA | Ciliate-E2a | 245-279 | 37 | 3.7e-07 | 17.16 | In-house | 241-275 (275) | Show / Hide |
Range on Protein: 245-279 Range on HMM: 241-275/275 Sequence Identity: 37% (13 aa) WPNCSNLAIDLITRLTNFSPSNRYNAGKSLNHPWI | .||. ..||. .. . |..|..| ||||| WEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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