Gene 6861 (Tetrahymena)

6861

Species: Tetrahymena
Alias: PreTt06861, 3715.m00007, TTHERM_00495960, 403, 62.m00145, 6861
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A9

Sequence

Name Sequence Type Origin Length Description Download
6861.AA Protein None 2353 None Fasta, JSON
6861.kin_dom Protein Kinase Domain None 268 None Fasta, JSON
6861.NA RNA None 7062 None Fasta, JSON

Protein domain

Protein domains of 6861.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 6861.AA Ciliate-A9 587-854 32 1.5e-243 590.36 In-house 1-392 (392) Show / Hide 
Range on Protein: 587-854
Range on HMM: 1-392/392
Sequence Identity: 32% (126 aa)

LLNGKPLGEGTSGCVYQCKKLNQEDETVYAVKVMRNVDEEMSKSIFQTFGIQYRLQHEYISRVYEV---------------------YFNEDNQTVHYVM
....|..|||..|||.||....|||...|||||.......|....||........||.....|...                     .|.|..|..|.||
FEPIKIIGEGAFGCVIQCRDIQQEDKQEYAVKVIQKNKMKMDCIEFQDQEAKILQQHDHPNIVKFKNIKNINTQKETKQLNYIFQISKFCESDQNIHIVM

DFIPFRTLDSVVKDKRRN---MKETEASGIIQKLLKAVMYMEQRGVCHRDLKPE----------------------------------------------
......||....|....|   ..|.|.|.|......|||||.|...|||||||.                                              
EYMKCGTLQQLMKERKKNNQWFNEQEISQIMKCIMSAVMYMHQKNICHRDLKPDRQINKCIQLFISSFIHLFINHHNYCKQQNKQTNKQTNEKINQVKIF

----NILIS--EDLQQLKIIDFGISKSFVKSQRVQHITQYYKHKMYTPTGTPHYKAPEILLGAGYTQLVD------------------------------
    ||||.  .||.|.||.|||.|||||||||||..||...|.||...||..|.|||......|.|.||                              
ILTENILIGDKNDLTQVKIADFGLSKSFVKSQRVQYFTQWTYHSMYQQCGTLIYMAPEFFINKQYSQPVDHAVSMKSRKRLIYLFLQLIILFLNSLKSQN

-------------MWAVGIIAYQLIAKGKHPFKCD--SNQEQDARIMKYQFDQTDEGWVNASSNAKNFIKSLLR---PNRMPAFEALKHPWI
             ||..|||.|.|...|||||.|.  .|...|...||.|.....|.|.|.|.||||||.....   .||..||..||||||
QFILYRQFKQQVDMWSCGIIMYMLLCMGKHPFWCPYEKNDDEDYFKMKIQCNPQWEFWDNCSNNAKNFIQKMTNINPSNRYNAFQCLKHPWI
Kinase 6861.AA S_TKc 587-854 26 1.2e-69 238.56 SMART 1-231 (231) Show / Hide 
Range on Protein: 587-854
Range on HMM: 1-231/231
Sequence Identity: 26% (75 aa)

LLNGKPLGEGTSGCVYQCKKLNQEDETVYAVKVMRNVDEEMSKSIFQTFGIQYRLQHEYISRVYEVYFNEDNQTVHYVMDFIPF--RTLDSVVKDKRRN-
   ....|.|. |.||.|.. .  .  ..|.|...       ..| .   |  . .|..| . |.|. .   . .. ||....    .| .. |...|. 
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----MKETEASGIIQKLLKAVMYMEQRGVCHRDLKPENILISEDLQQLKIIDFGISKSFVKSQRVQHITQYYKHKMYTPTGTPHYKAPEILLGAGYTQ-L
    . | .|  ... ...|. |. ..|..||||||||||..|   ..||.|||... .                 .|  |||.| |||.|   ||.   
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-----------------TTFCGTPWYMAPEVL---GYGKCK

VDMWAVGIIAYQLIAKGKHPFKCDSNQEQDARIMKYQFDQTDEGWVNASSNAKNFIKSLLRPN---RMPAFEALK-------HPWI
.|.|..|.| | ... |. ||       |.....|             |. ||.||. .|. .   |. | |||.       |||.
CDWWSCGCILYEMLC-GYPPFP------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 6861.AA CAMK 592-854 19 1.6e-64 206.53 In-house 1-425 (425) Show / Hide 
Range on Protein: 592-854
Range on HMM: 1-425/425
Sequence Identity: 19% (84 aa)

PLGEGTSGCVYQCKKL-NQEDE---------TVYAVKVMR----------------------------NVDEEMSKSIFQTFGIQYRLQ-------HEYI
 ||.|. | |. |.   .. .|         . .|.|..                             ...... |....   |  .||       |. |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

SRVYEVYFNED-----------------NQTVHYVM---DFIPFR----TLDSVVKDKRRN--------------MKETEASGIIQKLLKAVMYMEQRGV
 . |||| ...                 .. .. ||   ....       | . .......              ..| ||. ... .. || |. ....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDLKPENILISEDL----------------QQLKIIDFGISKSFVKSQR------VQHITQYYKH---------KMYTPTGTPHYKA-PEILLG----
.||||||||||....                  ..|||||| .. | ...       ... .   .          ||.|. |||.| | ||.|.|    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

----------AGYTQLVDMWAVGIIAYQLIAKGKHPFKCDSNQEQDA-------------RIMKYQFDQTDEG------------WVNASSN--------
           .|.. .|||..|.| | .   |. ||  |...|.               .||| ..|  ..             | . | .        
NMQNATDEEKPYYGPKCDMWSCGVILYIMLC-GYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE

AKNFIKSLLRPN---RMPAFEALKHPWI
.|..|...|...   || . ..|.|||.
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 6861.AA Ciliate-E2 587-854 22 3.9e-57 194.68 In-house 1-365 (365) Show / Hide 
Range on Protein: 587-854
Range on HMM: 1-365/365
Sequence Identity: 22% (84 aa)

LLNGKPLGEGTSGCVYQCKKLNQ---------------------EDETVYAVKVMRNVDEEMSKS---IFQTFG----------IQYRLQHEYISRVYEV
    | .|.|. |.||.||. ..                      .   ||.|.|.. . |. |.   |...            |. .|.| .| . ||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YFNEDNQTVHYVMDFIPFRTLDSVVKDKRRN----------MKETEASGIIQKLLK---------------AVMYMEQRG-VCHRDLKPENILISEDLQQ
. ..|.... .||...   .| .  |... .          ..| |.. |....|.               |. |. ... ..|||.||||||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

LKIIDFGISKSFVKSQRVQH------ITQYYKHKMYTPTG----------------TPHYKAPEILLGAG---------YTQLVDMWAVGIIAYQLIAKG
.||||||.|| . ...  .       . .. | .... .|                ||.|.||||| | .         |.  .|.|..|.| |...  |
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF-G

KHPFKCDSNQEQDARIM--KYQFDQTDEG------------WVNASSNAKNFIKS----LLRPN---RMP-AFEALKHPWI
|.||           |.  |..|.. . .            | . | ..|..||     .|  .   |.  . ..|.|||.
KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 6861.AA Pkinase 587-854 26 8.6e-55 193.14 Pfam 1-293 (293) Show / Hide 
Range on Protein: 587-854
Range on HMM: 1-293/293
Sequence Identity: 26% (83 aa)

LLNGKPLGEGTSGCVYQCKKLNQEDETVYAVKVMRNVDEEMSKSIFQTF----GIQYRLQHEYISRVYEVYFNEDNQTVHYVMDFIPFR----TLDSVVK
.  |...|.|..||||.|.. . ..  ..|||... ..|...| .  .      |  ||.|..| | |... .  .. .. ||.. .       | ....
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIS

-DKRRNM--KETEASGIIQKLLKAVMYMEQRGVCHRDLKPENILISEDLQQ---LKIIDFGISKSFVKSQRVQHITQYYKHKMYTPTGTPHYKAPEILL-
 ......   | |.  ..  .|... |. ..|..|||||||||||... .    .||.|||..| |             .. |.|..|||.| |||... 
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---------Y-NNS-MTTFCGTPWYMAPEVIRG

GAGYTQLVDMWAVGIIAYQLIAKGKHPFKCD------SNQEQDARIMKYQFDQTDEGWVNAS-----------------SNAKNFIKSLLRPNRM--P-A
| .|.. ||||..|.| |...  |. ||. .      . ..  .|||. ...   . | . |                 ...| |||..|...    | |
GQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

FEALKHPWI
 ..|.|||.
EQILQHPWF
Kinase 6861.AA Ciliate-E2-Unclassified 586-854 23 1.2e-52 180.92 In-house 1-352 (352) Show / Hide 
Range on Protein: 586-854
Range on HMM: 1-352/352
Sequence Identity: 23% (83 aa)

YLLNGKPLGEGTSGCVYQCKKLNQEDET----------VYAVKVMRNVDEEMSKSIFQTFGIQ---YR----------LQHEYISRVYEVYFNEDNQTVH
| .. | .|.|  |.||.|.. .|  .           .|..| ..|.| |.. .. . . ..    |          |.|  . .|...|  .| |.. 
YKII-KQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

YVMDFIPFRTLDSVVKDK----------------RRNMKETEAS-----GIIQKLLKAVMYMEQRG-VCHRDLKPENILISEDLQ--QLKIIDFGISKSF
 ||....  .|    |..                |.   | .|.      ..  .|..  |. . . ..|||.||||||.... .  ..|||||||||  
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

VKSQRVQHIT------QYYKHKMYTPTGTPHYK----APEILLGAGYT----QLVDMWAVGIIAYQLIAKGKHPFKCDSNQE----------------QD
 ...  .  .      ......|.| .||| |.    |||.| | .|       .|.|..|.|.|...  |..||.. .  .                . 
QQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLF-GYYPFYDNNCEQHQQLITQWINNAYRKQLY

ARIMKYQFDQTDEGW----VNASSNAKNFIK----SLL--RPN-RMPAFEALKHPWI
  |.. ....  . |     . | .||.||.    ..|  .|| |. . ..|.|||.
QNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 6861.AA CDPK 685-854 35 1.1e-48 147.58 In-house 101-271 (271) Show / Hide 
Range on Protein: 685-854
Range on HMM: 101-271/271
Sequence Identity: 35% (64 aa)

KETEASGIIQKLLKAVMYMEQRGVCHRDLKPENIL--ISEDLQ----QLKIIDFGISKSFVKSQRVQHITQYYKHKMYTPTGTPHYKAPEILLGAGYTQL
.|.||..|....| || |. .....||||||||||  . .| .    ..|.||.|.|| | ..|..       . ||..  |||.| |||.| .  | . 
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKI------EDKKMSQRCGTPYYIAPEVLQKK-YNEK

VDMWAVGIIAYQLIAKGKHPFKCDSNQEQDARIMKYQFDQTDEGWVNASSNAKNFIKSLLRP---NRMPAFEALKHPWI
.| |  |.| | |.  |  ||  .. ||  . ..| ...  .. | . |..||. |. .| .   .|| | .||.|||.
CDIWSCGVILYILLC-GYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 6861.AA CAMK1 686-854 36 3.3e-48 138.19 In-house 107-276 (276) Show / Hide 
Range on Protein: 686-854
Range on HMM: 107-276/276
Sequence Identity: 36% (66 aa)

ETEASGIIQKLLKAVMYMEQRGVCHRDLKPENIL-ISEDLQ-QLK--IIDFGISKSFV-KSQRVQHITQYYKHKMYTPTGTPHYKAPEILLG---AGYTQ
| .|. |....|.|| || ..|..||||||||.|  ..| . ..|  |.|||.|| |  ..            .|.|. ||| | |||.| .    .| .
EKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN-----------LMKTACGTPGYVAPEVLECKKDKPYDK

LVDMWAVGIIAYQLIAKGKHPFKCDS-NQEQDARIMKYQFDQTDEGWVNASSN-AKNFIKSLLRPN---RMPAFEALKHPWI
 .||| .|.| | |   |  ||  .. ..|  . |.|....     | | |.  ||.||| .| ..   |  . ..|.||||
ACDMWSIGVITYILLC-GYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 6861.AA CAMK-Unique 587-854 20 2.3e-44 144.26 In-house 1-363 (363) Show / Hide 
Range on Protein: 587-854
Range on HMM: 1-363/363
Sequence Identity: 20% (76 aa)

LLNGKPLGEGTSGCVYQCKKLNQEDETVYAVKVMRNVDEEMSKSIFQ--------------------TFGIQYRLQHEYISRVYEV---YFNEDNQ----
  .....|.|. | || |  ...| .. .|.|. .. . . .| . |                      .|  .. |. | ..|..    |  ..     
YKMHRIIGHGNFGHVYEC--MDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCD

----------TVHYVMDFIPFRTLDSVVKDK-------------------RRNMKE--TEASGIIQKLLKAVMYMEQRGVCHRDLKPENILISEDLQ---
            . ||.... ..| ... .                    .. . |  .... |.|.|| || || . .. |||||.|||.... ..   
LIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNN

------------QLKIIDFGISKSFVKSQRVQHITQYYKHK-MYTPTGTPHYKAP--------------EILLGAGYTQLV----DMWAVGIIAYQLIAK
             .|..|||... .  ..         .   | |  ||| |.||              |.. . .| | .    | |. | |.| ..  
HHRDFPYDWSNWHIKLCDFGLCCHYNHNK---------MCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLC-

GKHPFKCDSNQ--------EQDARIMKYQF-DQTDEGWVN---ASSNAKNFIKSLLRPN---RMPAFEALKHPWI
|..|| |...         |. ..|.| .. .   . |      | .||.|.| ..      | .| |.|.|.||
GCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 6861.AA CAMKL 586-854 26 4.3e-44 138.51 In-house 1-297 (297) Show / Hide 
Range on Protein: 586-854
Range on HMM: 1-297/297
Sequence Identity: 26% (83 aa)

YLLNGKPLGEGTSGCVYQCKK-LNQEDETVYAVKVMR----NVDEEMSKS-----------IFQTFGIQYRLQ---HEYISRVYEVYFNEDN----QTVH
| . || ||.|. | |  ..  ...  .. .|.|..     . |. |.|            |..   |. .|.   |. | . |||. ....    . ..
YRI-GKTLGKGSFGKVKLATHIRTT--GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIY

YVMDFIPFRT---LDSVVKDKRRN--MKETEASGIIQKLLKAVMYMEQRGVCHRDLKPENILISEDLQ-QLKIIDFGISKSFV-KSQRVQHITQYYKHKM
 ||  ..      .| .|| ..|.  |.| ||  . . .. || |. ..|..|||.||||||..|.   ..|||||| |  .  .          . .|.
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC-------IFGPGQKL

YTPTGTPHYKAPEILLG--AGYT-QLVDMWAVGIIAYQLIAKGKHPFKCDSNQ-------EQDARIMKYQFDQTDEGWVNASSNAKNFIKSLLRP---NR
 |  |.|.| ||||..|    |  . ||.|. |.| | ..  |. ||..|...       .   .||.  .  .    |  |  ....|...| .    |
KTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVC-GYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHV--S-DCRDLIRKMLQVNPEKR

MPAFEALKHPWI
. . . ..||| 
PTIHQIMNHPWM
Kinase 6861.AA CMGC 587-813 18 1.2e-42 137.42 In-house 1-368 (513) Show / Hide 
Range on Protein: 587-813
Range on HMM: 1-368/513
Sequence Identity: 18% (68 aa)

LLNGKPLGEGTSGCVYQCKKLN------------QEDETVYAVKVMRNV-DEEMSK----------SIFQTFGIQYRLQ-----------------HEYI
  . |..|||| | ||.|.  .             |.. ..|.| ..|. .||  |          ...    |  .|.                 |..|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

SRVYEVYFNED---------------NQTVHYVMDFIPF---RTLDSVVKD----KRRNMKETE------------ASGII------QKLLKAVM--YME
 . |...  ..               .. .. |.....    . ...  .|    ......| .               ..      . .|...   |. 
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

QRG--VCHRDLKPENILISEDLQQ-------------------LKIIDFGISKSFVKSQRVQHITQYY-----------KHKMYTPTGTPHYKAPEILLG
...  ..|||||||||||... .                    |||.||| .... . ... . .|.             . ...   | .|.|||||||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

AG----------YTQLVDMWAVGIIAYQLIAK-------GKHPFKCDSN-----------QEQDARIMK
..          ||. .|||.|| | . .. .       ||  |. .|.           ..| ..|.|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFK
Kinase 6861.AA STE 587-854 18 9.1e-41 141.69 In-house 1-359 (359) Show / Hide 
Range on Protein: 587-854
Range on HMM: 1-359/359
Sequence Identity: 18% (70 aa)

LLNGKPLGEGTSGCVYQCKKLN-----QEDET--------VYAVKVMRNVDE-----------------EMSKSIFQTFGIQYRLQ--HEYISRVYEVYF
. . . .|.|..| ||.... .     . .|.        ..|.|.|.  ..                 |  ..| .   |  ...  |..| . |  ||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NED-----NQTVHYVMDFIPFRTLDSVVK---DKRRNMK----------ETEASGIIQKLLKA-VMYMEQRGVCHRDLKPENILISEDLQQLKIIDFGIS
.|.     ..... .| ...  .||...|    . ....          |.. . |.. .||.   | .. .. |||.|| |||.       |..|||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

KSFVKSQR----------VQHITQYYKHKMYTPTGTPHYKAPEILLG------AGYTQLVDMWAVGIIAYQLIAKGKHPFKCDSNQEQDARIMKY-----
.....| .          .    .  . | .| .||| . |||....       ||.  .|.| .|. .  . | ||.|.   .. .   .|..      
GQLTDSMANIQSNNIIDCI----ETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM-ATGKPPWHDMHPMRAMFMIPFNYHMQQ

---------QFDQTDEGWVN-----------------ASSNAKNFIKSLLRPN---RMPAFEALK--HPWI
         .   . .  .                   |.. |.||.  |. .   |  | . ||  ||.|
QFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 6861.AA TyrKc 587-853 20 1.3e-09 -67.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 587-853
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

LLNGKPLGEGTSGCVYQCKKLNQEDETVYAVKVMRNVDEEMSKSIFQTFGIQYRL--QHEYISRVYEVYFNE-----DNQTVHYVMDFIPFRTLDSVVKD
.  || ||||  | ||...      ..| |||....      . . .   |  .|  .|. | | | |   .       . .  || . |   |..  ..
ITLGKKLGEGAFGEVYKGTWK----IQV-AVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KRRNMKETEASGIIQKLLKAVMYMEQRGVCHRDLKPENILISEDLQQLKIIDFGISKSFVKS-QRVQHITQYYKHKMYTPTGTPHYK--------APEIL
.|.. .  .   .     .   | ..... ||||   |.|..|.. . || ||| |.      |.         ...|..... . |        ||| .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQG------ESKDYYRKKEHKGGKTMLPIRWMAPECI

LGAGYTQLVDMWAVGIIAYQLIAKGKHPFKC-----DSNQEQDARIMKYQFDQTDEG-----WVNASSNAKNFIKSLLRPNRM--PAFEALKHPW
    .|   | |. |.  . .   |. |         ||||  .....       .       | ...   . .|.  . .    | |..... .
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 6861.AA CMGC 841-854 42 0.000856 7.32 In-house 500-513 (513) Show / Hide 
Range on Protein: 841-854
Range on HMM: 500-513/513
Sequence Identity: 42% (6 aa)

NRMPAFEALKHPWI
.|. | .||.||..
KRITAEQALQHPYF
Kinase 6861.AA CAMK1 589-620 30 0.038496 1.95 In-house 3-35 (276) Show / Hide 
Range on Protein: 589-620
Range on HMM: 3-35/276
Sequence Identity: 30% (10 aa)

NGKPLGEGTSGCVYQCKKLNQE-DETVYAVKVM
.|| .|.|. . ||.|.. .   ..  ||.|..
FGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCI