Gene 14048 (Tetrahymena)

14048

Species: Tetrahymena
Alias: 47.m00243, PreTt14048, 14048, 58, TTHERM_00426130
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C4

Sequence

Name Sequence Type Origin Length Description Download
14048.AA Protein None 922 None Fasta, JSON
14048.kin_dom Protein Kinase Domain None 342 None Fasta, JSON
14048.NA RNA None 2769 None Fasta, JSON

Protein domain

Protein domains of 14048.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 14048.AA Ciliate-C4 567-908 48 1.3e-227 736.57 In-house 1-361 (361) Show / Hide 
Range on Protein: 567-908
Range on HMM: 1-361/361
Sequence Identity: 48% (175 aa)

YQKLSLLGKGGFALVWLAKQYKTGISFAVKQICKQNGSDSHMREMRINQQ--FYDLEGEVKEYFHQFEGINNFLKCYE------IRHTQRDIFIVYELGG
|.|...||||||.||||.||.||...||.||||.||..|||.|.|.....  ||...|.||||...  |..|  .  .          | | .|.|||.|
YIKRKCLGKGGFSLVWLCKQKKTQQQFACKQICNQNNQDSHQRHMKEIWFYSFYMRNGQVKEYYQMYQGFKNLPQMMYNEILINYMKDQKDTWIIYELCG

GSLSSILYEIKG-EFYKNERVYKINFTELHDKLFQTKSNNLLRSLMRHFFNALDLLQNQKIVHCDVKPENILVELD---QSEASFQKVHLIDFGSCFSFK
.||...|||||| ....|||||||||..|...|||.|.|||......|...||..|...|.||||.|||||||...   ......|.|.||||||||.|.
KSLRKSLYEIKGEDYCQNERVYKINFKKLYYHLFQDKNNNLCKKFIQHICHALWHLHQNKWVHCDIKPENILVKYKSDFGGSNNIQQVKLIDFGSCFQFN

DVGSIG-MATPEYLAPEMLELFAQRFN------INNQVSQIEQLAKIANPWSVDMWSMGAVMLEVLTGLPHWLAYKCRVVDKQGKSNLKYGLFCTKGQDY
....|. ||||||..||||....|..|      .|.|......|.....|||.|.||||.||.|..||.|||..|||||..||.|...|.|.||.|.|..
NKKHIQSMATPEYMPPEMLNFIIQEQNEDEQLQQNHQHDMFQYLQNYECPWSIDIWSMGCVMMEIITGIPHWMSYKCRVHHKQVKNFIKHGIFCHKQQCF

EKIIQKQQQFCDNFSNNVKEITKQFDCQVTAKKFQDLLKKMMKFNSIERISPQQALQHPFF
|.|||||..||.......||...||.|||......||.|||.|||..|||||.|..|||..
ENIIQKQKKFCKQIDQYMKEHNYQFCCQVIDQQLKDLIKKMLKFNPRERISPKQCCQHPWI
Kinase 14048.AA S_TKc 567-908 17 2.4e-31 111.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 567-908
Range on HMM: 1-231/231
Sequence Identity: 17% (63 aa)

YQKLSLLGKGGFALVWLAKQYKTGISFAVKQICKQNGSDSHMREMRINQQFYDLEGEVKEYFHQFEGINNFLKCYEIRHTQRDIFIVYELGGG---SLSS
|..| ..|||.|. |....  |||  .|.|.|                    ... |..   ..  .  |  |.|.. ..  ....| |. .|   .| .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------------EHIRREIQ--ILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFD

ILYEIKGE-----FYKNERVYKINFTELHDKLFQTKSNNLLRSLMRHFFNALDLLQNQKIVHCDVKPENILVELDQSEASFQKVHLIDFGSCFSFKDVGS
.. . ...     |                      .    |..|.  ..||. . ...|.|.|.||||||.           . ..|||..  .    .
YIKKRGRHGLRFPF----------------------PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------HIKICDFGLARQL----T

IGMATPEYLAPEMLELFAQRFNINNQVSQIEQLAKIANPWSVDMWSMGAVMLEVLTGLPHWLAYKCRVVDKQGKSNLKYGLFCTKGQDYEKIIQKQQQFC
    ||.|.|||.|                       .. ..|.|| | .. | |.| | .                          .......|     
TFCGTPWYMAPEVL---------------------GYGKCKCDWWSCGCILYEMLCGYPPFP-------------------------QMQMMFKKIG---

DNFSNNVKEITKQFDCQVTAKKFQDLLKKMMKFNSIERISPQQALQ-------HPFF
                    . . |...|.....  .|..  .|||       ||.|
-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 14048.AA Ciliate-E2-Unclassified 567-908 20 1.6e-26 89.03 In-house 1-352 (352) Show / Hide 
Range on Protein: 567-908
Range on HMM: 1-352/352
Sequence Identity: 20% (83 aa)

YQKLSLLGKGGFALVWLAKQYKTGISFAVKQICKQNGSDSHMR-----------EMRINQQFYDLEGEVKEYFHQFEGIN-------------NFLKCYE
| ..  .|.|||. |..... |..  .| |...|..  ...             || ...  |. .            .|             . .|...
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQR-K----------YNKIMQQILLNHPHPFIVKMFY

IRHTQRDIFIVYELG-GGSLSSILYEIKG--EFYKNERVYKINFTELHDKLFQTK--SNNLLR-----SLMRHFFNAL-DLLQNQKIVHCDVKPENILVE
.  ..  |.||.|.  ||.|. .. . |.  .  |        . .| ... |.|  . .  .      ....  ..|  | ....|.| | ||||||. 
CFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQ--K--------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFD

LDQSEASFQKVHLIDFGSC-FSFKDVG----------------SIGMA-TPEYL----APEMLELFAQRFNINNQVSQIEQLAKIANPWSVDMWSMGAVM
 ...     .. .||||.. .. ....                .  .. ||.|.    |||.|    |. | ... .            ..|.||.| ..
NNGK---NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL----QGQNYDHSKA-----------YKCDIWSLGVIL

LEVLTGLPHWLAYKCRV-----VDKQGKSNLKYGLFCTKGQDYEKIIQKQQQFC--------DNFSNNVKEITKQFDCQVTAKKFQDLLKKMMKFNSIER
 | |.| .   ...|         ..   |     . .. | |..|.||..||         .. |...|.. .            |||.||.| |  .|
YEMLFGYYPFYDNNCEQHQQLITQWI-N-N-----A-YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIN------------DLLQKMLKKNPNKR

ISPQQALQHPFF
|...|.|.||.|
ITFEQILNHPWF
Kinase 14048.AA Ciliate-E2 567-773 18 8.7e-17 54.14 In-house 1-260 (365) Show / Hide 
Range on Protein: 567-773
Range on HMM: 1-260/365
Sequence Identity: 18% (54 aa)

YQKLSLLGKGGFALVWLAKQYKTGISFAVKQICKQNGSDSH-MREMRINQQFYDLEGEVK---EYFHQFEGIN----------------------NFLKC
| .. ..|.|.|. |...|..|..  || |.|  |.   .  | .   ....| ..   |   |.. | . |.                      | .|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQM-QEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKM

YEIRH--TQRDIFIVYEL-GGGSLSSILYEIKGEFYKNERVYKINFTELHDKLFQTKSNNLLRSLMRHF----FN---------------ALDLLQNQK-
||     ..  |..| |.  ||.| ..... |  . ..                . . ...    ....    ..               ||  | ... 
YECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE--------------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN

IVHCDVKPENILVELDQSEASFQKVHLIDFGSCFSFKDV--------------------GSIGMA--------------TPEYLAPEMLE
|.| | ||||||.           . .|||| .  ..|                     ...|                ||.|.|||.|.
IIHRDIKPENILF-----------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILN
Kinase 14048.AA Ciliate-E2 799-908 21 5.9e-15 47.75 In-house 276-365 (365) Show / Hide 
Range on Protein: 799-908
Range on HMM: 276-365/365
Sequence Identity: 21% (26 aa)

SVDMWSMGAVMLEVLTGLPHWLAYKCRVVDKQGKSNLKYGLFCTKGQDYEKIIQ-KQQQFCDNFSNNVKEITKQFDCQVTAKKF-------QDLLKK---
..|.||.| .. | |.| | .                           ...|.| | . .| .. .. .   .   | .  |..       .||.||   
KCDIWSLGVILYEMLFGKPPF---------------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKW--KSWKKWSQECKDLIKKFGK

-MMKFNSIERIS-PQQALQHPFF
 |.. .  .||. ..|.|.||.|
RMLQKDPEKRITGWEQILNHPWF
Kinase 14048.AA Ciliate-E2a 882-908 51 4.4e-14 37.86 In-house 249-275 (275) Show / Hide 
Range on Protein: 882-908
Range on HMM: 249-275/275
Sequence Identity: 51% (14 aa)

QDLLKKMMKFNSIERISPQQALQHPFF
.||.||| . . ..||..||||.||.|
KDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 14048.AA CMGC 840-908 15 4.6e-14 41.71 In-house 386-513 (513) Show / Hide 
Range on Protein: 840-908
Range on HMM: 386-513/513
Sequence Identity: 15% (20 aa)

FCTKGQDYEKIIQ---------------------------------KQQQFCDNFSNNVKEITKQFDCQ---------------------------VTAK
||.. ... ..|.                                 .... . ...| .. . .. | .                              .
FCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-NNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDP

KFQDLLKKMMKFNSIERISPQQALQHPFF
.. ||||||....  .||...||||||.|
QAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 14048.AA CMGC 567-753 11 1.7e-11 33.09 In-house 1-254 (513) Show / Hide 
Range on Protein: 567-753
Range on HMM: 1-254/513
Sequence Identity: 11% (33 aa)

YQKLSLLGKGGFALVWLAKQYKTGIS--------------FAVKQICKQNGSDSH--------------MREMRINQQF--YDLEGEVKEYFHQFE----
|.... .|.| .. |. ..  .|.                 |.| | ..   . .               || .| ...  ..   .        .    
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NW-------QRRDD

----GINNFLKCYEIRHTQR-----------------DIFIVYELGGGSLSSILYEIKG---------------------EFYKNERVYKINFTELHDKL
      || .|.|.| ..                   ....| |. . .|  .... ..                                         
PDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRP-------------------

FQTKSNNLLRSLM------RHFFNALD--LLQNQK--IVHCDVKPENILVELDQSEASF--------------QKVHLIDFGSCFSF
 .    .. ...|      .  ...|.   .  ..  |.|.| ||||||.  .    .                .. ..|||.. ..
-P----HNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWY
Kinase 14048.AA DYRK 879-908 46 2.2e-11 39.06 In-house 291-320 (320) Show / Hide 
Range on Protein: 879-908
Range on HMM: 291-320/320
Sequence Identity: 46% (14 aa)

KKFQDLLKKMMKFNSIERISPQQALQHPFF
..| |..||. ...  .||.|.||||||.|
HQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase 14048.AA CAMK 713-773 23 4.8e-10 27.81 In-house 195-293 (425) Show / Hide 
Range on Protein: 713-773
Range on HMM: 195-293/425
Sequence Identity: 23% (23 aa)

LQNQKIVHCDVKPENILVELDQSEASF-----------QKVHLIDFGSC--FSFKDVGSIG------------------------MATPEYLA-PEMLE
. ...|||.| ||||||.  . .. ..            .. .||||    |  ..                               |||| | ||.|.
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLN
Kinase 14048.AA Pkinase 715-817 27 4.9e-10 36.56 Pfam 126-210 (293) Show / Hide 
Range on Protein: 715-817
Range on HMM: 126-210/293
Sequence Identity: 27% (29 aa)

NQKIVHCDVKPENILVELDQSEASFQKVHLIDFGSC----FSFKDVGSIGMATPEYLAPEMLELFAQRFNINNQVSQIEQLAKIANPWSVDMWSMGAVML
...|.|.|.||||||.  .   ..  .|...|||..       .   .    ||.|.||| .                        . .|||||.| .. 
SMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR------------------GGQYYGPKVDMWSCGCILY

EVLTGLP
|.|.| |
EMLCGRP
Kinase 14048.AA STE 709-773 25 8.1e-10 30.97 In-house 163-235 (359) Show / Hide 
Range on Protein: 709-773
Range on HMM: 163-235/359
Sequence Identity: 25% (22 aa)

A-LDLLQNQKIVHCDVKPENILVELDQSEASFQKVHLIDFGSCFSFKDVG-------------SIG-MA-----TPEYLAPEMLE
. |..| ...|.| |.|| |||.           | |.||| | .. | .             ... .      || . |||...
GLLYYLHSHHIIHRDIKPANILL-----------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQ
Kinase 14048.AA CAMK 869-908 19 1.6e-09 26.09 In-house 379-425 (425) Show / Hide 
Range on Protein: 869-908
Range on HMM: 379-425/425
Sequence Identity: 19% (9 aa)

TKQFDCQVTAK-------KFQDLLKKMMKFNSIERISPQQALQHPFF
.....  ..           .||..||.. .  .|.. .|.|.||..
GPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 14048.AA DYRK 691-749 36 1.9e-09 31.71 In-house 96-153 (320) Show / Hide 
Range on Protein: 691-749
Range on HMM: 96-153/320
Sequence Identity: 36% (23 aa)

FQTK-SNNLLRSLMRHFFNALDLLQNQ-KIVHCDVKPENILVEL--DQSEASFQKVHLIDFGS
||   | || |.  .  ...|..|..  .|.||| |||||..    ..|.     . .|||||
FQGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKST-----IKVIDFGS
Kinase 14048.AA ULK 879-908 30 7.4e-09 27.63 In-house 295-324 (324) Show / Hide 
Range on Protein: 879-908
Range on HMM: 295-324/324
Sequence Identity: 30% (9 aa)

KKFQDLLKKMMKFNSIERISPQQALQHPFF
....||...|....  .||| .. ..||.|
PECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 14048.AA CAMKL 567-617 27 1.2e-07 20.26 In-house 1-69 (297) Show / Hide 
Range on Protein: 567-617
Range on HMM: 1-69/297
Sequence Identity: 27% (19 aa)

YQKLSLLGKGGFALVWLAKQ-YKTGISFAVKQICKQNGS-DSHMR----------------EMRINQQF
|. .  ||||.|. | ||.    ||.  |.| | |.  . | .|.                |..| ...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKML
Kinase 14048.AA Ciliate-E2a 567-600 41 2.1e-07 17.91 In-house 1-34 (275) Show / Hide 
Range on Protein: 567-600
Range on HMM: 1-34/275
Sequence Identity: 41% (14 aa)

YQKLSLLGKGGFALVWLAKQYKTGISFAVKQICK
| .. ..||| |. | ||.. .||  ||.| . |
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK
Kinase 14048.AA Pkinase 567-602 33 3.7e-07 26.4 Pfam 1-36 (293) Show / Hide 
Range on Protein: 567-602
Range on HMM: 1-36/293
Sequence Identity: 33% (12 aa)

YQKLSLLGKGGFALVWLAKQYKTGISFAVKQICKQN
|.... .|.|.|. |....  .||. .|||.|.|..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRH
Kinase 14048.AA CAMKL 882-908 33 4.6e-07 18.44 In-house 271-297 (297) Show / Hide 
Range on Protein: 882-908
Range on HMM: 271-297/297
Sequence Identity: 33% (9 aa)

QDLLKKMMKFNSIERISPQQALQHPFF
.||..||.. |  .|.. .| ..||..
RDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 14048.AA CAMKL 715-748 41 8.1e-07 17.63 In-house 145-174 (297) Show / Hide 
Range on Protein: 715-748
Range on HMM: 145-174/297
Sequence Identity: 41% (14 aa)

NQKIVHCDVKPENILVELDQSEASFQKVHLIDFG
...||| | ||||||.  ....    .. .||||
SHGIVHRDIKPENILLDENGNN----NIKIIDFG
Kinase 14048.AA Pkinase 881-908 32 8.4e-07 25.14 Pfam 266-293 (293) Show / Hide 
Range on Protein: 881-908
Range on HMM: 266-293/293
Sequence Identity: 32% (9 aa)

FQDLLKKMMKFNSIERISPQQALQHPFF
..|..|.. ...  .|....|.||||.|
CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 14048.AA Ciliate-E2a 636-748 22 2e-06 14.88 In-house 60-154 (275) Show / Hide 
Range on Protein: 636-748
Range on HMM: 60-154/275
Sequence Identity: 22% (26 aa)

NFLKCYEIRHTQRDIFIVYEL-GGGSLSSILYEIKGEFYKNERVYKINFTELHDKLFQTKSNNLLRSLMRHFF-NALDLLQNQKIVHCDVKPENILVE-L
| .| ||.  . . ...|.|.  ||.| . . . | .|..                      .  ...|. ..  .|  .....|.| | |||||| . .
NIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE---------------------IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNC

DQSEASFQKVHLIDFG
... .  ... .||||
SKNSIQNSDIKIIDFG
Kinase 14048.AA CAMK 572-598 25 1.2e-05 13.38 In-house 1-39 (425) Show / Hide 
Range on Protein: 572-598
Range on HMM: 1-39/425
Sequence Identity: 25% (10 aa)

LLGKGGFALVWLAKQYKTG------------ISFAVKQI
 ||.|.|. | |... .|.              .|.| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKII
Kinase 14048.AA STE 879-908 28 2.2e-05 15.1 In-house 328-359 (359) Show / Hide 
Range on Protein: 879-908
Range on HMM: 328-359/359
Sequence Identity: 28% (9 aa)

KKFQDLLKKMMKFNSIERISPQQALQ--HPFF
..|.| ..|  . .  .| ...| |.  |||.
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 14048.AA ULK 700-730 32 2.4e-05 14.97 In-house 129-159 (324) Show / Hide 
Range on Protein: 700-730
Range on HMM: 129-159/324
Sequence Identity: 32% (10 aa)

RSLMRHFFNALDLLQNQKIVHCDVKPENILV
.. .... |..  |....|.|.| ||.|||.
IQFFKQICNGFKELHKHNIIHRDIKPQNILI
Kinase 14048.AA ULK 567-606 29 3.9e-05 14.24 In-house 1-44 (324) Show / Hide 
Range on Protein: 567-606
Range on HMM: 1-44/324
Sequence Identity: 29% (13 aa)

YQKLSLLGKGGFA-LVWLAKQYKT---GISFAVKQICKQNGSDS
|..   |||| |.  |  ..  ||   .  .|.|.| |.. ...
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKK
Kinase 14048.AA STE 567-617 17 0.000107 12.65 In-house 1-85 (359) Show / Hide 
Range on Protein: 567-617
Range on HMM: 1-85/359
Sequence Identity: 17% (15 aa)

YQKLSLLGKGGFALVWLAKQYK---------------TGISFAVKQICKQNG-------------------SDSHMREMRINQQF
..... .|||.|  | .|.  |               ||  .|.||. ..|                     .. ..|..| ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKC
Kinase 14048.AA TyrKc 567-868 13 0.000245 -152.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 567-868
Range on HMM: 1-280/280
Sequence Identity: 13% (49 aa)

YQKLSLLGKGGFALVWLAKQYKTGISFAVKQICKQNGSDSHMREMRINQQFYDLEGEVKEYFHQFEGINNF-------LKCYEIRHTQ-------RDIFI
 ...  || | |  |.... .   |  ||| . .                       ...  .  .   ..       ...| .  .|         ..|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMI

VYEL-GGGSLSSILYEIKGEFYKNERVYKINFTELHDKLFQTKSNNLLRSLMRHFF-----NALDLLQNQKIVHCDVKPENILVELDQSEASFQKVHLID
| |.  .|.| . | . ...                           |     . |     .  . |  ....| |    |.||  ..       |   |
VMEYMPHGDLKDYLRKHRPK---------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISD

FG-SCFSFKD--------VGSI-----GM--ATPEYLAPEMLELFAQRFNINNQVSQIEQLAKIANPWSVDMWSMGAVMLEVLT--GLPHWL-AYKCRVV
|| | .   |        . .      |        .||| .  .  .|..                   | || | .| |..|  . |..  . .  . 
FGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTTK-----------------SDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMS

DKQGKSNLKYGLFCTKGQD--------YEKIIQKQ-QQFCDN-------FSNNVKEI
...   ..| |    . ..          . . .  .| ..        ||. ....
NQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 14048.AA DYRK 799-817 47 0.007558 6.81 In-house 184-202 (320) Show / Hide 
Range on Protein: 799-817
Range on HMM: 184-202/320
Sequence Identity: 47% (9 aa)

SVDMWSMGAVMLEVLTGLP
..|||| | .. | .|| |
AIDMWSLGCILAELFTGWP
Kinase 14048.AA DYRK 567-596 36 0.022224 5.04 In-house 1-30 (320) Show / Hide 
Range on Protein: 567-596
Range on HMM: 1-30/320
Sequence Identity: 36% (11 aa)

YQKLSLLGKGGFALVWLAKQYKTGISFAVK
|. |. .||| |. |  ... ||.  .|.|
YEILEYIGKGSFGQVVKCWDHKTNEMVAIK
Kinase 14048.AA CMGC 799-815 47 0.044093 1.59 In-house 315-331 (513) Show / Hide 
Range on Protein: 799-815
Range on HMM: 315-331/513
Sequence Identity: 47% (8 aa)

SVDMWSMGAVMLEVLTG
..|||| | .. | .||
PIDMWSVGCIFAEMYTG
Kinase 14048.AA STE 799-817 42 0.123231 1.7 In-house 248-266 (359) Show / Hide 
Range on Protein: 799-817
Range on HMM: 248-266/359
Sequence Identity: 42% (8 aa)

SVDMWSMGAVMLEVLTGLP
..|.|| | ...| .|| |
KCDIWSLGCTIIEMATGKP