Gene 24721 (Tetrahymena)

24721

Species: Tetrahymena
Alias: 775, 267.m00040, TTHERM_01187290, PreTt24721, 24721
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C5

Sequence

Name Sequence Type Origin Length Description Download
24721.AA Protein None 318 None Fasta, JSON
24721.NA RNA None 954 None Fasta, JSON
24721.kin_dom Protein Kinase Domain None 234 None Fasta, JSON

Protein domain

Protein domains of 24721.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 24721.AA CK1-Unclassified 12-248 68 1.5e-208 621.58 In-house 1-244 (244) Show / Hide 
Range on Protein: 12-248
Range on HMM: 1-244/244
Sequence Identity: 68% (167 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFYEVKLYQYLLQDE---TIIDKGIPQVYYCSTE--GEYNIMVMDLLGPSLEDLFNFCNR
.....|.|.|.||||....|...| |||||||  |.|||||.||.|..|||  ..    .| |||| .|.|..|  |.||||||||||||||||||.|||
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFI-KGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNR

RFSLKTVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIG-SGKRSNKVFIIDFGLAKRYLQ--RDGTHIPYRDNKNLTGTARYASINTHLGIEQGRRDDL
.||||||||.|.||.|||||.|...|.||||||||||.| .||....|.||||||.|||..  ..|.|||||.||||||||||||||.||||||.|||||
KFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDL

ESLGYVLMYFLRGSLPWQNLKANNKKDKYERIMEKKLSTPVEVLC
|||||||.|||.|||||||.||||||.|||.|||.|.||||| ||
ESLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase 24721.AA CK1 12-274 68 2.7e-203 681.68 In-house 1-271 (271) Show / Hide 
Range on Protein: 12-274
Range on HMM: 1-271/271
Sequence Identity: 68% (186 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVE--VAIKLEPVNTKHPQLFYEVKLYQYLLQDETIID---KGIPQVYYCSTE--GEYNIMVMDLLGPSLEDLFNFC
....||.|.|.||.|..| |..|..|  ||||||. ..||||| ||.|.|..|  .  . |   .|||..|.| .|  |.||||||||||||||||||||
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGH-NC-DNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFC

NRRFSLKTVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIGS-GKRSNKVFIIDFGLAKRYLQ-RDGTHIPYRDNKNLTGTARYASINTHLGIEQGRRDD
||.||||||||.|.||.|||||||...|.||||||||||.|  ||....|.||||||||||.. ....|||||.|||||||||||||||||||||.||||
NRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD

LESLGYVLMYFLRGSLPWQNLKANNKKDKYERIMEKKLSTPVEVLCKS-FPDEFVKYLAYCRNLRFDEKPDYN
.||||||||||||||||||.||||.||.|||.|||||.|||||.|||  || ||. || |||.|.|.||||| 
MESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase 24721.AA CK1-D 12-276 67 8.99999999999e-162 543.73 In-house 1-261 (261) Show / Hide 
Range on Protein: 12-276
Range on HMM: 1-261/261
Sequence Identity: 67% (179 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFYEVKLYQYLLQDETIIDKGIPQVYYCSTEGEYNIMVMDLLGPSLEDLFNFCNRRFSLK
... ||.|||.||.|.|| |...| |||||||.. |||||| .| |.|...     |   |||.. .|  ||.||.|||||||||||||||.|.|.||||
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQ--GGI---GIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLK

TVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIGSGKRSNKVFIIDFGLAKRYLQRD-GTHIPYRDNKNLTGTARYASINTHLGIEQGRRDDLESLGYVL
||||||.||..||||.| | |.||||||||||.| ||| | |.||||||||||       |||||.||||||||||||||||.|||| ||||||||||||
TVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVL

MYFLRGSLPWQNLKANNKKDKYERIMEKKLSTPVEVLCKSFPDEFVKYLAYCRNLRFDEKPDYNYC
||| ||||||| ||| .|..|||||.|||.||....||| .| ||..|..|||||.||.|||| | 
MYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase 24721.AA CK1-A 12-276 63 1.4e-147 496.61 In-house 1-261 (261) Show / Hide 
Range on Protein: 12-276
Range on HMM: 1-261/261
Sequence Identity: 63% (170 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFYEVKLYQYLLQDETIIDKGIPQVYYCSTEGEYNIMVMDLLGPSLEDLFNFCNRRFSLK
..| ||.|||.||.|. |.|..|  |||||.|  . .|||| || |.|. |         |||.. .  .| .||.|||||||||||||||||.|||..|
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQG-----CVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMK

TVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIGSGKRSNKVFIIDFGLAKRYL-QRDGTHIPYRDNKNLTGTARYASINTHLGIEQGRRDDLESLGYVL
||||||.||. ||||||.. |.||||||||||.| |.  ||.|.|||||||.|  .|  .|||||. ||||||||||||| |||||| ||||.||.|||.
TVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVM

MYFLRGSLPWQNLKANNKKDKYERIMEKKLSTPVEVLCKSFPDEFVKYLAYCRNLRFDEKPDYNYC
||| ||.|||| .||..|| |||.| |||.|||.|.||| || ||  |..|||||||.|.||| | 
MYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase 24721.AA CK1-G 12-276 55 4.7e-145 488.19 In-house 1-266 (266) Show / Hide 
Range on Protein: 12-276
Range on HMM: 1-266/266
Sequence Identity: 55% (151 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFYEVKLYQYLLQDETIIDKGIPQVYYCSTEGEYNIMVMDLLGPSLEDLFNFCNRRFSLK
..  .| | | |||.| | |. ||. ||||.||. .. |||  | . |. | .       |||||||   .| |||||||||||||||||..|.|.||.|
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCP----EGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVK

TVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIG--SGKRSNKVFIIDFGLAKRYLQRD-GTHIPYRDNKNLTGTARYASINTHLGIEQGRRDDLESLGY
||.|.| ||..|.|||| .| . ||.||||||||  | |. ....|||||.|| |   . . |||||  | ||||||| ||||||| || ||||.|.|| 
TVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGH

VLMYFLRGSLPWQNLKANNKKDKYERIMEKKLSTPVEVLCKS--FPDEFVKYLAYCRNLRFDEKPDYNYC
. ||||||||||| ||| | | .|..| ..| .|..|.||..  ||..| .|| | |.| |.|.|||.| 
MFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase 24721.AA CK1 12-276 39 4.7e-137 461.62 In-house 1-339 (339) Show / Hide 
Range on Protein: 12-276
Range on HMM: 1-339/339
Sequence Identity: 39% (134 aa)

FKLTRKLGSGAFG-EIFHG-----VNLKNN-----VEVAIKLEPVNTK--HPQLFYEVKLYQYLLQD----------ETIID----KGIPQVYYCSTEGE
.|...|.|.|.|| .|...     ...|||      |.|.|.||....  |||| .|...|..| .           .   .    ...| .|....|..
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

--YNIMVMDLLGPSLEDLFN---FCNRRFSLKTVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIGS------GKRSN--------KVFIIDFGLAK-RY
  ||.|||.||||.||||..   .|||.||.||.||.|.|||...||.| ..|.|||||||||..|       ||. .        .|..||||.|. .|
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKY

LQRDGT------------HIPYRD---NKNLTG-TARYASINTHLGIEQGRRDDLESLGYVLMYFLRGS--LPWQNLKANNK-------KDKYERIMEKK
. .||.            |.|.|.   .|...| ||||.|||.|||.||||||||.|..|.|...|.|.  |||||.|...|       | ||| |.|||
RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK

LSTPVEVLCKS-----FPDEFVKYLAYCRNLRFDEKPDYNYC
.|||.. ||.      .|.|| |.. |.|.|.....||| . 
MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase 24721.AA Worm6 12-276 27 1.1e-65 224.5 In-house 1-279 (279) Show / Hide 
Range on Protein: 12-276
Range on HMM: 1-279/279
Sequence Identity: 27% (78 aa)

FKLTRKLGSGAFGEIFHGVNLKNNV--EVAIKLEP--VNTKHPQLFYEVKLYQYLLQDE-----TIIDKGIPQVYYCSTEGE-YNIMVMDLLGPSLEDLF
.|.|.|.|.|.|| ..   . ...   ..|.|.|    | |...|  |.   . . .       .|.|.|        .. . .| .|| |.|..|.|| 
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGK-------VDNRGFNYIVMTLVGKNLWDLR

NFC-NRRFSLKTVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIGS-----GKRSNKVFIIDFGLAK--RYLQRDGTHIPYR-DNKNLTGTARYASINTH
 .. .|.||. | | .|.|.|..|| .|. .|.|||.|| || ||       . . .....|||...  .|. .... .. | ..    || |||... |
KNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACH

LGIEQGRRDDLESLGYVLMYFLRGSLPWQNLKANNKKD-KYERIMEKKLSTPVEVLCKSFPD-EFVKYLAYCRNLRFDEKPDYNYC
 |.||.|.||.||  |..  ...| |||...|. . ..  ..... .. ..  . . . .|  ||.. . |  .... ..|||...
KGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase 24721.AA TTBK 12-276 37 4.2e-58 199.36 In-house 1-257 (257) Show / Hide 
Range on Protein: 12-276
Range on HMM: 1-257/257
Sequence Identity: 37% (100 aa)

FKLTRKLGSGAFGEIFHGVNLKNN-VEVAIKLEPVNTKHPQLFYEVKLYQYLLQDETIIDKGIPQVYYCSTEGEYNIMVMDLLGPSLEDLFNFCNR-RFS
 | ..| | |.||||. . .. |.  .||||.| ....   |  ||   . |   . .      . . |  . ..| |||.|.| .| ||     |  ||
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVC-----RFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFS

LKTVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIG-SGKRSNKVFIIDFGLAKRYLQRDGTHIPYRDNKNLTGTARYASINTHLGIEQGRRDDLESLGY
| | | |  |.|| || .|   |||||||| || .|   .. .|....||||| .|.   |   | |      ||.|||||| |.  | ||.||| || |
LSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFY

VLMYFLRGSLPWQNLKANNKKDKYERIMEKKLSTPVEVLCKSFPDEFVKYLAYCRNLRFDEKPDYNYC
.|  |. | |||  .     ||| . . | |      .| |  | ||  ...  . | . ..|||   
MLVEFVQGQLPWRKI-----KDK-DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase 24721.AA TTBKL 12-280 28 2.1e-55 185.56 In-house 1-288 (288) Show / Hide 
Range on Protein: 12-280
Range on HMM: 1-288/288
Sequence Identity: 28% (85 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNT-KH-PQLFYEVKLYQYLLQDETIIDKGIPQVYYCSTEGEYNIMVMDLLGPSLEDLF--NFCNRR
.. ....|.|.||...|....|.  ..|.. |..|.  . ..   .     ..||..    . .|.....  .. || ||| |.||.| ||   . ...|
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPN--GSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKR

FSLKTVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIGSGKR----SNKVFIIDFGLAKRYLQRDG-----------THIPYRD---NKNLTGTARYASI
||  |.. .. | |  . ..|   |.|||.|| |. .|  ..    .  |..||||.|..|.  ||           .. . |.      . || ||.|.
FSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSP

NTHLGIEQGRRDDLESLGYVLMYFLRGSLPWQNLKANNKKDKYERIMEKKLSTPVEVLCKS------FPDEFVKYLAYCRNLRFDEKPDYNYCQSLF
| |.. |||| ||| |. |...... | |||.|..        ..|...|...  |.|.|       .|.|| |   . |.||. . ||| . . .|
NMHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDK------MEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase 24721.AA Pkinase 12-267 21 8.2e-39 138.32 Pfam 1-258 (293) Show / Hide 
Range on Protein: 12-267
Range on HMM: 1-258/293
Sequence Identity: 21% (59 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFY------EVKLYQYLLQDETIIDKGIPQVYYCSTEGEYNIMVMDLLGPSLEDLFNFC-
... ||.|||.||. ..... ... .||.|  .. .....  .      |... . | . . |.     . |.. ... .  |||....  |. ..  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIV-----RLYDWFEDKDHIYMVMEYCEGGLY-VMDLFD

------NRRF--SLKTVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIG-SGKRSNKVFIIDFGLAKRYLQRDGTHIPYRDNKNLTGTARYASINTHL-G
      ...|  | ... . . |.|. .|| | . ..|||.||.|.||   |  . .| |.|||||| .      . ... .. ..|| .|..   .. |
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGG

IEQGRRDDLESLGYVLMYFLRGSLPWQNL----KANNKKDKYERIMEKKLSTPVEVLCKSFPDEFVKYLAYCRNLRF
 . |.. |  |.| .| ..| | .|...     . .... ...|||...|. . . .|   ... ...   .. ...
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWT
Kinase 24721.AA VRK 88-229 38 2.3e-29 91.54 In-house 106-251 (284) Show / Hide 
Range on Protein: 88-229
Range on HMM: 106-251/284
Sequence Identity: 38% (57 aa)

MVMDLLGPSLEDLFN-FCNRRFSLKTVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIGSGKRSNKVFIIDFGLAKRYLQRDGTHIPYRDNKNLT--GTA
|||. .| .|. .    .. ||| |||| || .||   || |     | |||  | | |  |  ..|. .|.||| || . .| | .|  ..     || 
MVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRY-CPNGKHRQYKEDPRRCHNGTC

RYASINTHLGIEQGRRDDLESLGYVLMYFLRGSLPWQNLKA--NNKK
 . |.  |.|    || |||.||| .|. | |.||| ...   . .|
EFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPWMDCLQQQDPEK
Kinase 24721.AA S_TKc 12-280 20 1.5e-15 51.12 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-280
Range on HMM: 1-231/231
Sequence Identity: 20% (58 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFYEVKLYQYLLQDETIIDKGIPQVYYCSTEGEYNIMVMDLLGPSLEDLFNFCNRR----
... ||.|.||||. . ... | . .||||  .      ..  |... .          . | . |..  . ..  |||.... .| ||| .  .|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FSLKTVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIGSGKRSNKVFIIDFGLAKRYLQRDGTHIPYRDNKNLTGTARYASINTHLGIEQGR-RDD
    |.  ..  .. |... .|| | ....|||.||.| |. .      . |.|||||...             . . ||  | .         |. . |
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCD

LESLGYVLMYFLRGSLPWQNLKANNKKDKYERIMEKKLSTPVEVLCKSFPDEFV----KYLAYCRNLRFDEKPDYNYC-----QSLF
  |.| .|  .| |  |..     . .  ...|.               ..|.     | | .  . |       ...        |
WWSCGCILYEMLCGYPPFP-----QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 24721.AA TyrKc 12-280 18 4e-09 -75.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-280
Range on HMM: 1-280/280
Sequence Identity: 18% (57 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFYEVKLYQYLLQDETIIDKGI-P------QVYYCSTEG-------EYNIMVMDLLGP-S
 .| .|||.|||||...|.     ..||.|    ..            .  . .|  | . . .      . | . |..       |   .|| .    .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

LEDLFNFCNRRFSLKTVLMLAEQMLQRIEYVHHRHFLHRDIKPDNFLIGSGKRSNKVFIIDFGLAKRYLQRDGT---HIPYRDNK--NLT--GTARYASI
| |    . .....|. |  . |  .  || |.... |||.   | |.|...    | | ||||..     | .   .  ||  .  .       |  ..
LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

NTHLGIEQGRRDDLESL-GY------------VLMY--FLRGSLPWQNLKA--NNKKDKYERIMEKKLSTPVEVLCKS-----FPDEFVKYLAYCRNLRF
              |..  .            |.|.  | .|  |. .      . .. .|.... .   . .  .        |||  .    | .   
--------------ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDP

DEKPDYNYCQSLF
.. |  . . ..|
EDRPTFSEIHECF
Kinase 24721.AA Pkinase_Tyr 12-41 35 2e-07 25.75 Pfam 1-34 (270) Show / Hide 
Range on Protein: 12-41
Range on HMM: 1-34/270
Sequence Identity: 35% (12 aa)

FKLTRKLGSGAFGEIFHGVNL----KNNVEVAIK
 .. .|||.|||||...|.      .....||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK
Kinase 24721.AA VRK 12-68 25 5.8e-05 12.33 In-house 1-61 (284) Show / Hide 
Range on Protein: 12-68
Range on HMM: 1-61/284
Sequence Identity: 25% (16 aa)

FKLTRKLGSGAFGEIFHG---VNLKN--NVEVAIKLEPVNTKHPQLFYEVKLYQYLLQDETI
..| .. |.| ||.|.     .. ..  .    .|.||   .   || |.. ||  .. | |
WRLGKPIGQGGFGCIYLASPNTCKPCEKDAQYVVKIEP-PHENGPLFTEMHFYQRAAKPEQI