Gene 15451 (Tetrahymena)

15451

Species: Tetrahymena
Alias: 3811.m00986, 15451, 52.m00229, PreTt15451, TTHERM_00449380, 236
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C6

Sequence

Name Sequence Type Origin Length Description Download
15451.AA Protein None 452 None Fasta, JSON
15451.kin_dom Protein Kinase Domain None 271 None Fasta, JSON
15451.NA RNA None 1359 None Fasta, JSON

Protein domain

Protein domains of 15451.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15451.AA Ciliate-C6 166-436 67 1.6e-206 692.4 In-house 1-306 (306) Show / Hide 
Range on Protein: 166-436
Range on HMM: 1-306/306
Sequence Identity: 67% (207 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQSMPDYYACKQIHISQDG--ENQSQQIFHEIEVLEKLRKYENVIKLQNYIIE-ERSTYLVLDLAESTL
.|||||.|.||||||||.|||.||||||.||||.|||||||||||..|..  |||..||||||||||||.|||||||.|||.|| .|.||.|||||||||
INYRDSLGSGSFGQVYKCKNKHKQIIKNMDILQQMPDYYACKQIHMTQQMSFENQMSQIFHEIEVLEKLKKYENVIKMQNYFIEPNRQTYIVLDLAESTL

QDKINEKQTN------------------SEKFDESEIVKFLSQIGKTLALIYIEEGIAHRDIKPSNILIKDD--NFYLSDFGCAEILFESHEARNN-LVM
||.|..||.|                  .|.|||.|||.|..|||||||.||.|..|||||||||||||.||  |.||||||||. ||.|...||| ..|
QDCIQMKQANVNNFYFKQEINIFSFNYKYEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQQLFQSEFTRNNDIHM

GTLKWMSPELKEMKK----------NQVVDYFKSDIFSLGMLLLYMLTLSDISSVNSDEFTKNQKIRIMKNYCKGIS-NEIILLIKRMLETNPDNRPDAA
||||||||||.||||          ||..||||.|||||||.|||||||||||.||.|||.||||||||||.||.|| .|||.|...|||||||.|||..
GTLKWMSPELREMKKQYNQHQDDNSNQQIDYFKCDIFSLGMILLYMLTLSDISQVNCDEFMKNQKIRIMKNMCKDISYKEIIKLVSKMLETNPDHRPDMS

IIINAI
|.|..|
ILIQTI
Kinase 15451.AA Pkinase 166-436 21 3.7e-38 135.99 Pfam 1-293 (293) Show / Hide 
Range on Protein: 166-436
Range on HMM: 1-293/293
Sequence Identity: 21% (68 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQSMPDYYACKQIHISQDGENQSQQIFH--EIEVLEKLRKYENVIKLQNYIIEERSTYLVLDLAES---
.     || ||||.||| ..|  ..             .|.|.|  . . ... |. ..  ||... .| . .|...|  .  .... |.|....|    
YHIGRKIGSGSFGCVYKCHHKGTGK------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLY

--TLQDKIN--EKQTNSEKFDESEIVKFLSQIGKTLALIYIEEGIAHRDIKPSNILIK-DDNF----YLSDFGCAEIL-FESHEARNNLVMGTLKWMSPE
   | | |   .. . .  |.| |. ... || . |. ..  .|| |||.||.||||. ...      ..|||.|. .   . .  . .. ||. .|.||
VMDLFDYISTWRHGCFY--FSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC-GTPWYMAPE

LKEMKKN-QVVDYFKSDIFSLGMLLLYMLT----LSDI----SSVNSDEFTKNQKIRIMKNYCK--------------------GISNEIILLIKRMLET
.     . .  .  |.|..|.| .| .||.     ..     . .. ..  .. . .. .  .                      .| | . .||..|. 
V----IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

NPDNRPDAAIIINA--I
.|  || |. | .   .
DPKKRPTAEQILQHPWF
Kinase 15451.AA S_TKc 166-444 23 4.9e-35 123.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 166-444
Range on HMM: 1-231/231
Sequence Identity: 23% (69 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQSMPDYYACKQIHISQDGENQSQQIFHEIEVLEKLRKYENVIKLQNYIIEERSTYLVLDLAES---TL
    . || |.||.|||...|                ..|.|.|.         ..|  ||..|.|  . .|..||  .. .  . |.|.....    .|
YEILRKIGKGAFGKVYKCRHKK------------TGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDL

QDKINEKQTNS--EKFDESEIVKFLSQIGKTLALIYIEEGIAHRDIKPSNILIKDDNFYLSDFGCAEILFESHEARNNLVMGTLKWMSPELKEMKKNQVV
 | | .....    .|.| .. ... || . |. .    || |||.||.|||. . .  ..||| | .|        . . ||. .|.||.         
FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-HIKICDFGLARQL--------TTFCGTPWYMAPEVL------GY

DYFKSDIFSLGMLLLYMLT----LSDISSVNSDEFTKNQKIRIMKNYCKGISNEIILLIKRMLETNPDNRPDAAIIINAIQDIE-NNFK
...|.|. |.| .|  ||.     .             |  ...|. .   | | . .|...|. .|..|| |  . .. .||    . 
GKCKCDWWSCGCILYEMLCGYPPFP-------------QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15451.AA Ciliate-E2 166-434 21 3.3e-30 100.88 In-house 1-361 (365) Show / Hide 
Range on Protein: 166-434
Range on HMM: 1-361/365
Sequence Identity: 21% (79 aa)

LNYRDSIGCGSFG-----QVYKVKNKYKQIIKNPDILQSMP---DYYACKQIHISQDGENQSQQIFHEIEVLEKLR---------------KYENVIKLQ
 .    || |.||     .|.||....  .|.. ... . .   .... |.. . .  .|| .||. || .. ...               .  |.||. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

NYII--EERSTYLVLDLAES-TLQDKINEKQTNS-------EKFDESEIVKFLSQIGKTL-------------ALIYIEE-G-IAHRDIKPSNILIKDDN
 . .   . . |||.....  .|.| |.......       ..|.| || ..  || .               || |. . . | ||||||.|||.    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

FYLSDFGCAEILFESHEARN------------------------------NLVMGTLKWMSPELKEMKK-----NQVVDYFKSDIFSLGMLLLYMLTL--
  ..||| . .. .... |                               | . ||.  |.||  ..||     .|    .|.||.|||..| .||.   
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

--SDISSVNSDEFTKNQKIRIMKNYCK--------GISNEIILLIKR----MLETNPDNRPD-AAIIIN
   ..   .  .| .....   .. |.         .|.| . |||.    ||. .|..|.. .  |.|
PFQQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 15451.AA STE 166-429 20 3.7e-29 100.14 In-house 1-348 (359) Show / Hide 
Range on Protein: 166-429
Range on HMM: 1-348/359
Sequence Identity: 20% (73 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQ----SMPDYYACKQIHISQDG---------------ENQSQQIFHEIEVLEKLRK-YENVIKLQNYI
.   . || |.||.||| .|. . .|  .   .    .. ...| ||......                ... ||| .||... |...  .|..|   . 
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

IEER-------STYLVLDLAE-STLQDKINEK----QTNS------EKFDESEIVKFLSQIGKTLA-LIYIE-EGIAHRDIKPSNILIKDDNFYLSDFGC
. |        . .... . .  .| | |..|    ....       .|.||.| ... ||    . | |..  .| ||||||.|||.      |.|||.
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQI--LKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGV

AEILFES--------------HEA-RNNLVMGTLKWMSPELKEMKKNQ-VVDY-FKSDIFSLGMLL-------LYMLTLSDISSVNSDEFTK--------
. .| .|                . ..| . ||  ||.||  .  ..  . .| .|.|| ||| ..         . .... .      | .        
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----NQKIRIMKNYC---------------KGISNEIILLIKRMLETNPDNRPDA
     ..  ..  . .               .  | | .  |.. |. .|..||.|
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTA
Kinase 15451.AA ULK 164-426 21 6.4e-28 96.19 In-house 1-312 (324) Show / Hide 
Range on Protein: 164-426
Range on HMM: 1-312/324
Sequence Identity: 21% (71 aa)

YELNYRDSIGCGSFG-QVYKVKNKYKQIIKNPDILQSMPDYYACKQIHISQDGENQSQ--------QIFHEIEVLEKLR--KYEN--VIKLQNYIIEE--
|.|| .  .| |||| .||| .|| ..             |.|||.| ...  .....        ..  ||... ||   | .|  ..||  .  .   
YCLNHC--LGKGSFGVKVYKGRNKKTNT---------QNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNH

RSTYLVLDLAES-TLQDKINEKQT-----NSEKFDESEIVKFLSQIGKTLALIYI-EEGIAHRDIKPSNILIKDDNFY-------------LSDFGCAEI
  .|..... .  .|.. |.....     .  .. |.|...|. ||    .. .. ...| ||||||.||||.... .             ..||| | .
NNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQI--CNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKH

LFESHEARNNL--------VMGTLKWMSPELKEMK-KNQVVDYFKSDIFSLGMLLLYMLTLS------DISSV--NSDEFTK-------NQKIRIMKN--
...  .. . .        . ||   |.|.. . . ...  . .|.||.|||... .||. .        . .  . ..  .        ..  | ..  
VDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKP

-YCKGISNEIILLIKRMLETNPDNR
 . . ||.|.. ||.|||. ... |
PKDPKISPECKDLIRRMLQYDEKDR
Kinase 15451.AA ULK 164-426 22 2e-25 85.77 In-house 1-317 (329) Show / Hide 
Range on Protein: 164-426
Range on HMM: 1-317/329
Sequence Identity: 22% (74 aa)

YELNYRDSIGCGSFGQVYKVKNKYKQ--IIKNPDILQSMPDYYACKQIH---ISQDGEN-----QSQQIFHEIEVLEKLR-------KYENVIKLQNYII
|.|| .  .| ||||.||| .|| ..  . .          ..|||.|    ..|.  .     . |..  ||... ||        . .|..||  .  
YCLNHC--LGKGSFGKVYKGRNKKTKDYVNE----------KVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFE

EE--RSTYLVLDLAES-TLQDKINEKQT------NSEKFDESEIVKFLSQIGKTLALIYI-EEGIAHRDIKPSNILIKDDNFY-------------LSDF
.     .|..... .  .|.. |.....      .  .. |.|...|. ||    .. .. ...| ||||||.||||.... .             ..||
TSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQI--LNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADF

GCAEILFES--HEARNNLVM------GTLKWMSPELKEMK-KNQVVDYFKSDIFSLGMLLLYMLT------LSDISSVNSDEFTKNQKIR------IMKN
| |  . ..   .. .          ||   |.|.. . . ...  . .|.||.|||... .||.       . ... .    .|. ...      | |.
GFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQ

YCK----G----ISNEIILLIKRMLETNPDNR
  .    |    ||.|.. ||.|||. ... |
PLQFPKDGNDPQISPECKDLIRRMLQYDEKDR
Kinase 15451.AA CAMK 171-379 18 9.6e-25 76.04 In-house 1-329 (425) Show / Hide 
Range on Protein: 171-379
Range on HMM: 1-329/425
Sequence Identity: 18% (63 aa)

SIGCGSFGQVYKVKNK-YKQIIKNPDILQSMPDYYACKQIHIS----------------QDGENQS----------QQIFHEIEVLEKLRK------YEN
 .| ||||.|.....|  .. ..   |.   .  .|.| |  .                .. ....          .....|||.. ||..       .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

VIKLQNYIIE-------------------ERSTYLVL---DLAEST-----LQDKINEKQTNSEK-----------FDESEIVKFLSQIGKTLALIYIEE
.|||  ..                     ..  |.|.   ....       | |.| |.  ..|.           |.|.|  ..  ||    |. |. .
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQI--CSAVHYCHS

-GIAHRDIKPSNILIKDDNF---------------Y---LSDFGCAEILFESHEARNN----------------------LVMGTLKWMS-PELKEMKK-
 .|.|||.|| |||. |.|                .   ..||| | ....... ...                       . ||.  |. ||. . |. 
HNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

-------NQVVDY--FKSDIFSLGMLLLYMLT
       ..  .|  .|.|. |.| .|  ||.
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLC
Kinase 15451.AA CMGC 166-324 19 3.5e-21 65.53 In-house 1-249 (513) Show / Hide 
Range on Protein: 166-324
Range on HMM: 1-249/513
Sequence Identity: 19% (49 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIK---NPDILQSMPDYYACKQIHISQDGENQSQ----------QIFHEIEVLEKLR---------------KYEN
    . ||.|..|.||| ..|  .  |       .     ..| | |   .  |.| .           .. ||. |..|.               | .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQ-AHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHN

-VIKLQNYIIEER-----------------STYLVLDLAESTLQDKINEKQT-----NSEKFDESE------------IVKFL------SQIGKTLALIY
 ..||....  .                  . ||| .. . .| . | ..|.     .  ...| .            | .|.       || . |.| |
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

IEEG---IAHRDIKPSNILIKDDNF---------------------YLSDFG
.      | |||.||.|||| ...                       . |||
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFG
Kinase 15451.AA Ciliate-E2-Unclassified 164-429 18 7.4e-21 69.1 In-house 1-343 (352) Show / Hide 
Range on Protein: 164-429
Range on HMM: 1-343/352
Sequence Identity: 18% (67 aa)

YELNYRDSIGCGSFGQVYKV---KNKYKQIIKNPDILQSMPDYYACKQIHIS--QDGENQSQQIFHEIEVLEK---------------LRKYENVIKLQN
|....   || |.||.|||.   |.|.....|           |..|.....  |  ... . .. ..|. .|               |.   . ...  
YKIIKQ--IGQGGFGKVYKCQHKKQKQYYAMK-----------YMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKM

YIIEERS--TYLVLDLAES-TLQDKINEKQTNS-------------EKFDESEIV-----KFLSQIGKTLAL-IYIEEG-IAHRDIKPSNILIKDD----
. ...     |.|....|  .|.. |... ...             ..|.| ...     ... ||   ..|  ..... | ||||||.|||....    
FYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQI--LQGLEYLHHKNNIIHRDIKPENILFDNNGKNY

NFYLSDFGCAEILFES--------------HEARNNLVMGTLKWM----SPELKEMKKNQ---VVDYFKSDIFSLGMLLLYMLT-LSDISSVNSDE----
.  ..||| .  . ..               . . . ..||.  |    .||. . ...        .|.||.|||..| .||.     .. |...    
YIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA---YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQL

------------FTKNQKIRIMKNYC-------KGISNEIILLIK----RMLETNPDNRPDA
            . .|.| .. .. .       |..|.| . .|.    .||. ||..|...
ITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITF
Kinase 15451.AA TKL 172-436 15 2.2e-20 70.11 In-house 1-364 (364) Show / Hide 
Range on Protein: 172-436
Range on HMM: 1-364/364
Sequence Identity: 15% (60 aa)

IGCGSFGQVYKVKNKY----KQIIKNPDILQSMP----DYYACKQIHISQ------------DGEN-----------QSQQIFHEIEVLEKLRK--YENV
|| |.||.||| | .     .            |       | |.... .            | .|           .|.  |.|.|..  ...   .|.
IGSGGFGEVYKGKWRGWGGKC------------PSDTGKDVAVKKFKSHNDDEFTKNSQENND-NNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNI

IKLQNYIIEERS-------------TYLVLDLA-ESTLQDKINEKQTNSEKFDESEIVKFLSQIGKTLALIYIEE---------GIAHRDIKPSNILIKD
...  | .....              ..| ...   .| . ..           . ....  .|   ... |            .|.|||.|..|||...
VQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDI--ARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDE

DN---------------FYLSDFGCAEILFESHE------------------ARNNLVMGTLKWMSPEL--KEMKKNQVV---------DYF-KSDIFSL
..                 ..||| .  ...| .                   ... . ||. ||.||.  ..|. .. |         .|. |.|..| 
NWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSF

GMLLLYMLTLSDISSVNSDEFTKNQK------IRIMKNY--------------------CKGISNEIILLIKRMLETNPDNRPDAAIIINAI
|..|  .||      . .|.    ..      . .|...                    |. .  ... |...  ...|..|| .  |.  .
GIVLWEILTRCR---PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 15451.AA NAK 166-324 25 2.9e-17 54.13 In-house 1-171 (299) Show / Hide 
Range on Protein: 166-324
Range on HMM: 1-171/299
Sequence Identity: 25% (44 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQSMPDYYACKQIHISQDGENQSQQIFHEIEVLEKLRKYENVIKLQN-YII-EERST-----YLVLDLA
.  .  .. | |..||.|.. |  .. |     | .. || | . |....|.. ... .|||...||.. .|....   .|  ...|.     .|.. . 
YTVEKYLAEGGFSYVYLVQDNYINHPDN---PNSNGEKYALKRM-ICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYC

ES-TLQDKINEKQT-NSEKFDESEIVKFLSQIGKTLALI-YIEE--GIAHRDIKPSNILIK----DDNFYLSDFG
.  .|.| .|.... .  .| | ||....... . .. . ..    .|.|||||. |||..    |.|. | |||
CHGSLWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCDFG
Kinase 15451.AA TyrKc 166-436 15 1.5e-11 -36.05 SMART 1-280 (280) Show / Hide 
Range on Protein: 166-436
Range on HMM: 1-280/280
Sequence Identity: 15% (47 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQSMPDYYACKQIHISQDGENQSQQIFHEIEVLEKL-RKYENVIKLQNYIIEE-------RSTYLVLDL
.   . .|.| ||.||| . |                  | | .. .       . . .|.... ||  . .|...|  .....          ..|. .
ITLGKKLGEGAFGEVYKGTWK---------------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEY

AE-----STLQDKINEKQTNSEKFDESEIVKFLSQIGKTLALIYIEEGIAHRDIKPSNILIKDDN-FYLSDFGCAEILFES------HEARNN----LVM
..     . |... ..       .  .. ..|  || .  . .    .. |||.   |.|.....    |||| .  . .       ..           
MPHGDLKDYLRKHRPK-------LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

--GTLKWMSPELKEMKKNQVVDYFKSDIFSLGMLL--LYMLTLSDISS-----VNSDEFTKNQKIRIMKNYCKG--------ISNEIILLIKRMLETNPD
    ..||.||      |  .  .|||..| | ..  .. .  .  .      .. .|  .. | . .    .          . |.  ..|.  . .|.
TMLPIRWMAPECI----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPE

NRPDAAIIINAI
.||  . |.  .
DRPTFSEIHECF
Kinase 15451.AA NAK 408-436 31 9.9e-07 18.41 In-house 271-299 (299) Show / Hide 
Range on Protein: 408-436
Range on HMM: 271-299/299
Sequence Identity: 31% (9 aa)

SNEIILLIKRMLETNPDNRPDAAIIINAI
|.... ||. ||...|..||. . ..| .
SQQMHDLIRYMLTPDPEQRPNIYQVLNQL
Kinase 15451.AA CAMK 405-434 26 0.00022 9.25 In-house 384-421 (425) Show / Hide 
Range on Protein: 405-434
Range on HMM: 384-421/425
Sequence Identity: 26% (10 aa)

KGISNE--------IILLIKRMLETNPDNRPDAAIIIN
..||.|         . ||..||...|..|. .. . |
DDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLN