Gene 5844 (Tetrahymena)

5844

Species: Tetrahymena
Alias: TTHERM_01498820, 424.m00008, PreTt05844, 5844, 972
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C7

Sequence

Name Sequence Type Origin Length Description Download
5844.AA Protein None 266 None Fasta, JSON
5844.kin_dom Protein Kinase Domain None 146 None Fasta, JSON
5844.NA RNA None 801 None Fasta, JSON

Protein domain

Protein domains of 5844.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 5844.AA Ciliate-C7 114-258 82 2.2e-110 355.01 In-house 1-146 (164) Show / Hide 
Range on Protein: 114-258
Range on HMM: 1-146/164
Sequence Identity: 82% (120 aa)

FRFLGQGQQGLVLLAKNSKTNMRYAIKGVQVRDSFGNLDEDLNNRVRQEVEILQKCRDSPYVVRLLDQFEGQQFSYLVLTECQ-GTLTQILERNQNKRLN
||||||||||||||||..|||||||||||||||. ||.|.|.||.|.||..||..|.||||||.||.|||||||.||||.||| |||.||.|||||||||
FRFLGQGQQGLVLLAKDQKTNMRYAIKGVQVRDKQGNIDQDINNQVQQEINILKQCKDSPYVVCLLHQFEGQQFIYLVLNECQGGTLNQIIERNQNKRLN

EISAIKYANDIAQGLYYIHSKSCLVNDLKMDNILIDYHGNAVVCKF
||||||||.||||||||||||.|.|||||||||||||.|||||| |
EISAIKYAKDIAQGLYYIHSKNCVVNDLKMDNILIDYNGNAVVCDF
Pkinase 5844.AA Pkinase 111-256 27 5.3e-23 82.42 Pfam 1-154 (293) Show / Hide 
Range on Protein: 111-256
Range on HMM: 1-154/293
Sequence Identity: 27% (43 aa)

YSDFRFLGQGQQGLVLLAKNSKTNMRYAIKGVQVRDSFGNLDEDLNNRVRQEVEILQKCRDSPYVVRLLDQFEGQQFSYLVLTECQG-----TLTQILER
|   | .|.|  | | .... .|. ..|.| . .|.   . |. . ..  .|..|.... ..|..|||.| ||  .  |.|.  |.|      |  ....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

NQNKRL--NEISAIKYANDIAQGLYYIHSKSCLVNDLKMDNILIDYHGNA----VVC
 .....   |  ...|.  |..||.|.||....  ||| .||||| .|.      .|
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKIC
Kinase 5844.AA ULK 111-248 25 2.8e-19 64.02 In-house 1-164 (329) Show / Hide 
Range on Protein: 111-248
Range on HMM: 1-164/329
Sequence Identity: 25% (42 aa)

YSDFRFLGQGQQGLVLLAKNSKT----NMRYAIKGVQ---VRDSF----GNLDEDLNNRVRQEVEILQKCRD---SPY----VVRLLDQFEGQQF--SYL
|.  . ||.|. | |  ..| ||    |  .|.| ..    . .     |   . . . ...|..|..|  .   ...    .|.|.| || ...   |.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEG---QYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYI

VLTECQG-TLTQILERNQN--------KRLNEISAIKYANDIAQGLYYIHSKSCLVNDLKMDNILID
..  |.| .| |....|..        |||.|  ||..  .|..|. ..|.. .   |.| .||||.
IMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIH
Kinase 5844.AA ULK 111-247 26 5.9e-19 63.93 In-house 1-159 (324) Show / Hide 
Range on Protein: 111-247
Range on HMM: 1-159/324
Sequence Identity: 26% (42 aa)

YSDFRFLGQGQQG-LVLLAKNSKT---NMRYAIKGVQVR-DSFGNLD---EDLNNRVRQEVEILQKCR--DSPY--VVRLLDQFEGQ--QFSYLVLTECQ
|.  . ||.|. |  |  ..| ||   |  .|.| ..    .  ...   . . .  ..|..|..|     .|.  .|.|.| || .   . |...  |.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

G-TLTQILERNQN-------KRLNEISAIKYANDIAQGLYYIHSKSCLVNDLKMDNILI
| .| |....|..       |||.|  ||..  .|..|. ..|.. .   |.| .||||
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILI
Kinase 5844.AA Ciliate-E2-Unclassified 111-256 21 6.4e-19 62.27 In-house 1-189 (352) Show / Hide 
Range on Protein: 111-256
Range on HMM: 1-189/352
Sequence Identity: 21% (40 aa)

YSDFRFLGQGQQGLVLLAKNSKTNMRYAIKGVQVRDSFG-NLDEDLNNRVRQEVEILQKCR------------------DSPYVVRLLDQFEGQQFSYLV
|   . .|||..| | .....|..  ||.|   .  ..  .. .  . .  .| .....                    ..|..|.....|. .|  |.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LTEC-QGTLTQILE---------------RNQNKRLNEISAI-----KYANDIAQGLYYIHSKS-CLVNDLKMDNILIDYHG---NAVVC
.  | .|.| |...               ..|.|.. |  |.     .|.  | ||| |.|.|  ..  |.| .|||.|  |   .  ..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKII
Kinase 5844.AA CAMK 116-256 17 7.3e-18 53.47 In-house 1-238 (425) Show / Hide 
Range on Protein: 116-256
Range on HMM: 1-238/425
Sequence Identity: 17% (42 aa)

FLGQGQQGLVLLAKNSKTN------------MRYAIKGVQVRDSFGNL----------------------DEDLNNRVRQEVEILQKCR------DSPYV
 ||.|. | | |... .|.             ..||| .  .   ..                       ..    .||.|.||..|..      | | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLLDQFEG-------------------QQFSYLVL---TECQGT------LTQILERNQN------------KRLNEISAIKYANDIAQGLYYIHSKSC
..|.. .|                    ... |.|.     |.|       .  | |. ..            .|..|  | .|   |.... |.||.  
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LVNDLKMDNILIDYH-----------------GNAVVC
   ||| .|||.|..                 .|  ..
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKII
Kinase 5844.AA Ciliate-E1 117-258 18 8.7e-18 54.8 In-house 1-153 (202) Show / Hide 
Range on Protein: 117-258
Range on HMM: 1-153/202
Sequence Identity: 18% (29 aa)

LGQGQQGLVLLAKNSKTN-MRYAIKGVQVRDSFGNLDEDLNNRVRQEVEILQKCRDSPYVVRLLDQFEGQQ--FSYLVLTECQGTLTQILE---------
.|.| ...|. ||. ..|   .|.| ..... .   ......  ... .|..  .   |.. ..|... .|  ........|. .|.. |.         
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNY--NQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQ

--RNQNKRLNEISAIKYANDIAQGLYYIHSKSCLVNDLKMDNILIDYHGNAVVCKF
  ..... ...   .. . .. .|| ..|..  .  |.|..||||.  || | |.|
QCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDF
Kinase 5844.AA CAMKL 111-256 25 1.1e-17 52.93 In-house 1-171 (297) Show / Hide 
Range on Protein: 111-256
Range on HMM: 1-171/297
Sequence Identity: 25% (43 aa)

YSDFRFLGQGQQGLVLLAKN-SKTNMRYAIKGVQVR----DSFGNLD------EDLNNRVRQEVEILQKCR--DSPYVVRLLDQFEGQQF------SYLV
|   . ||.|  | | ||.. . |. ..||| .  .    | . .        |.   |.|.|..|... .    | ...|.. .| ...       |||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LTECQGT---LTQILERNQNKR--LNEISAIKYANDIAQGLYYIHSKSCLVNDLKMDNILIDYHG--NAVVC
.  |.|    | . .... ..|  . |  | .|   |  ...|.||.     |.| .|||.|..|  |. ..
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKII
Kinase 5844.AA Ciliate-E2 111-257 18 6.9e-17 54.48 In-house 1-196 (365) Show / Hide 
Range on Protein: 111-257
Range on HMM: 1-196/365
Sequence Identity: 18% (39 aa)

YSDFRFLGQGQQGLVLLAKNSKT-----------------------NMRYAIKGVQVRD-SFGNLDEDLNNRVR------QEVEILQKCRDSPYVVRLLD
|   . .|||..| | ..|. |.                       .. ||.| .. ..  . .  ........      .| .||..  ..|..... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQL-NHPNIIKMYE

QFE--GQQFSYLVLTECQG-TLTQILERN----------QNKRLNEISAIKYANDIAQ---------------GLYYIHSKS-CLVNDLKMDNILIDYHG
 |.   ..  |||.  ||| .| .... |          . |...|  ....   |.|               .| |.|||  ..  |.| .|||.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

NAVVCK
    .|
----IK
Kinase 5844.AA STE 111-233 18 5.9e-15 49.36 In-house 1-171 (359) Show / Hide 
Range on Protein: 111-233
Range on HMM: 1-171/359
Sequence Identity: 18% (31 aa)

YSDFRFLGQGQQGLVLLAKNSK---------------TNMRYAIKGVQVRDS-----------FGNLDEDLNNRVRQEVEILQKCRD-SPYVVRLLDQFE
. . ...|.|  | | .|.| |               |. ..||| . ....             | ...  ... .|..|..||.. .|..|. .. ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

GQ-------QFSYLVLTECQ-GTLTQILE------RNQN------KRLNEISAIKYANDIAQG-LYYIHSK
         .  ....  .  |.|..|..      ...|      .|..|   .... .| .| |||.||.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSH
Kinase 5844.AA AGC 114-252 23 8.3e-15 33.24 In-house 1-193 (395) Show / Hide 
Range on Protein: 114-252
Range on HMM: 1-193/395
Sequence Identity: 23% (46 aa)

FRFL---GQGQQGLVLLAKNS------KTNMRYAIKGVQVRD---------SFGNLDE-------DLNNRVRQEVEILQKCRD---------SPYVVR-L
|.||   |.|  | | |..         |.  ||.| .. ..            .. |       .    |..| .||.||.          .|..|. |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGY----VWEERNILEKCNHTHNHPIKSHHPFIVKIL

LDQFEGQQF--SYLVLTECQ----------G-TLTQILERN-QNKRLNEISAIKYAND-------IAQGLYYIHS-KSCLVND-LKMDNILIDYHGN
   |. ..    |.|.  ..          |  | ..|    ...|..|  |  ||         |. .| |.|| .     | || .|||.| .|.
HYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGH
Kinase 5844.AA S_TKc 111-265 17 4.1e-09 -43.31 SMART 1-231 (231) Show / Hide 
Range on Protein: 111-265
Range on HMM: 1-231/231
Sequence Identity: 17% (44 aa)

YSDFRFLGQGQQGLVLLAKNSKTNMRYAIKGVQVRDSFGNLDEDLNNRVRQEVEILQKCRDSPYVVRLLDQFEGQQFSYLVLTECQG---TLTQILERNQ
|   | .|.|  | | .... ||. ..||| .              ...|.|..||.|  . |..|.|.| |.  .. |.|.  | |   .| .......
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

NKR----LNEISAIKYANDIAQGLYYIHSKSCLVNDLKMDNILID------------------------------YHG----------------------
 ..    ..|  | .|.  |...| |.||.  .  ||| .|||.|                              | .                      
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPF

---------------NAVVCKFLT-NTN--------K----------L
                  ..| |. . .        .          .
PQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF