Gene 26699 (Tetrahymena)

26699

Species: Tetrahymena
Alias: 11.m00396, 3702.m00118, PreTt26699, 26699, TTHERM_00144910, 493
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
26699.AA Protein None 1372 None Fasta, JSON
26699.kin_dom Protein Kinase Domain None 292 None Fasta, JSON
26699.NA RNA None 4119 None Fasta, JSON

Protein domain

Protein domains of 26699.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26699.AA CDK 92-383 30 3.7e-70 223.62 In-house 15-284 (284) Show / Hide 
Range on Protein: 92-383
Range on HMM: 15-284/284
Sequence Identity: 30% (101 aa)

VYKARRKVDQ-----KIVALKKII--------EESPSPS---QGMNILKRLDTHPNLVKLLDIVIEKDANLT------TSTFFVFEYCEHDLEGMFLSKI
||||| | ..     .|||||||.        |.   |.      ..|| |  ||| |||.|... |.   .      .. ..||||..||| .      
VYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD---

RFNLPQIKRVIHSILMGLSELQKKNIIHRDIKTDNILYNKNRE-----IKVADFGLSKDLNI------KRAPLSKKLQNIFYRAPESLLGSQHYS--FKV
      ||  .. .| ||. . ...|.|||.|. |||.|.| |     .|.|||||..  .|      .. .....     ||||| ||||.|||    .
------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPI

DIWCAGIIFYQLL-FRNQENVTYKALFAANFD-EQLKQAKNYFSLLGNPENENIWSQNSKNELKMKDYDAVLSQITPEEKANFKNRFIEHLKGINPNVDD
|.| .| ||. ..       || |.||  . . .||.     | ..| | .|..|   .|  .                                     
DMWSVGCIFAEMFTD-----VTRKPLFPGDSEIDQLFKI---FRICGTP-TEDNWPGVTKLPDY------------------------------------

SALDLLSKMLTLDPSLRFSADECLQHEFF
   |||.|||..||. |.||...|||..|
---DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 26699.AA CMGC 92-383 20 3.6e-64 209.39 In-house 15-513 (513) Show / Hide 
Range on Protein: 92-383
Range on HMM: 15-513/513
Sequence Identity: 20% (102 aa)

VYKARR--------------KVDQKIVALKKIIEESPSPSQGM----------------NILKRL----------------DTHPNLVKLLDIVIEKDAN
|||.|               . ...|||.||| ..   . |.                  |||.|                . |.|.|||.||.  |. .
VYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSD

LT------------TSTFFVFEYCEHDLEGMFLSKI---------RFNLPQ------------IKRVI------HSILMGLS--ELQKKN--IIHRDIKT
 .             . ..||||..||| ..  ..           ..  .            ||  .      . || ||    . ...  |||||.| 
GNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKP

DNILYNKNRE--------------------IKVADFGLSKDLNIK---------------------RAPLSKKLQNIFYRAPESLLGSQHYS--------
 ||| |.| |                    .|..||||.. ...                      . |..   .  .||||| |||..||.        
ENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHY

-FKVDIWCAGIIFYQLLFRNQENVTY-----KALFAANFDE---------QLKQAKNYFSLLGNPE--------------NENIWSQNSKNELK------
  ..|.| .| ||. .. . |          | ||  . ..          . | .  | .||.|               .|..| . .|.         
TTPIDMWSVGCIFAEMYTGYQ----SLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKK

----------MKDYDAVLSQ---ITPEEKANFKNRFIEHLKGINPN----------------------------VDDSALDLLSKMLTLDPSLRFSADEC
          ....   ...     .  . ..|| |  | .... |                             |. |.|||.|||..||. | .|...
WNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-NNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQA

LQHEFF
|||..|
LQHPYF
S_TKc 26699.AA S_TKc 85-383 22 1.7e-57 198.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 85-383
Range on HMM: 1-231/231
Sequence Identity: 22% (74 aa)

VLLINRL-------VYKARRKVDQKIVALKKIIEESPSPSQGMNILKRLDTHPNLVKLLDIVIEKDANLTTSTFFVFEYCEH---DLEGMFLSKIR----
  ... .       |||.| | ...|||.|.|     .  . ..|||.   |||.|||.|.  .      .. ..|.|||..   ||  .  .. |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FNLPQIKRVIHSILMGLSELQKKNIIHRDIKTDNILYNKNREIKVADFGLSKDLNIKRAPLSKKLQNIFYRAPESLLGSQHYSF-KVDIWCAGIIFYQ
  |.  ....... |. .|  . ...|||||.| .||| ..  .||..||||.. |       .      .|.||| |    .|.. |.|.|  |.|.| 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

LLF-----RNQENVTYKALFAANFDEQLKQAKNYFSLLGNPENENIWSQNSKNELKMKDYDAVLSQITPEEKANFKNRFIEHLKGINPNVDDSALDLLSK
.|      . |.....| .                                                                       ...|.|...|
MLCGYPPFP-QMQMMFKKIG----------------------------------------------------------------------SPEAKDFIRK

MLTLDPSLRFSADECLQ-------HEFF
.|. ||. | .| |.||       |..|
CLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 26699.AA Pkinase 92-383 25 3e-51 181.39 Pfam 15-293 (293) Show / Hide 
Range on Protein: 92-383
Range on HMM: 15-293/293
Sequence Identity: 25% (83 aa)

VYKARRKVDQKIVALKKIIEESPSPSQ--------GMNILKRLDTHPNLVKLLDIVIEKDANLTTSTFFVFEYCEH-----DLEGMFLS---KIRF--NL
|||...| ..||||.|.|  .. ....           |.|||  ||| |.|.|.. .      ..  .|.||||.     ||   ..|   . .|    
VYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLF-DYISTWRHGCFYFSE

PQIKRVIHSILMGLSELQKKNIIHRDIKTDNILYNKNREI----KVADFGLSKDLNIKRAPLSKKLQNI----FYRAPESLLGSQHYSFKVDIWCAGIIF
 ..|...  || ||  . ...|||||.| .|||...| .|    |..||||.| ..      .  .. .    .|.||| ..|.|.|. |||.| .|.|.
WECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCIL

YQLLFRNQENVTYKALFAAN--FDEQLKQAKNYFSLLG--NPENENIWSQNSKNELKMKDYDAVLSQITPEEKANFKNRFIEHLKGINPNVDDSALDLLS
|..|...        .|      |. . | . ..  .|  .....  |. .|  .  .  . .                  . ..   .|......|...
YEMLCGR-------PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H------------------F-HWTF-HNWSEECKDFIK

KMLTLDPSLRFSADECLQHEFF
..|..||. | .|...|||..|
WCLCKDPKKRPTAEQILQHPWF
Kinase 26699.AA Ciliate-E2 92-383 18 4.8e-46 156.04 In-house 15-365 (365) Show / Hide 
Range on Protein: 92-383
Range on HMM: 15-365/365
Sequence Identity: 18% (79 aa)

VYKARRKVDQKIVALK----------------------KIIEESPSPSQGM--NILKRLDT---------------HPNLVKLLDIVIEKDANLTTSTFF
|||.... .|| .|.|                      ||....   .. .  .|.....                |||..|. .  .|||   ... ..
VYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKD---DNNIYL

VFEYCEH-DLE-------GMFLSKIR----FNLPQIKRVIHSIL---------------MGLSELQKKN-IIHRDIKTDNILYNKNREIKVADFGLSKDL
|.|||.. ||.         ....|     |.. .||...  ||                .| .| .|| ||||||| .|||.     ||..||||||..
VMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKY

NIKRA-----PLSKKLQNIF---------------------------YRAPESLLG--------SQHYSFKVDIWCAGIIFYQLLFRNQENVTYKALFAA
....      ...|.... .                           | ||| | |        ...|..|.|||..|.|.|..|| .            
DDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---------

NFDEQLKQAKNYFSLLGNPENENIWSQNSKNELKMKDYDAVLSQITPEEKANFKNRFIEHLKG---------------------INPNVDDSALDLLSK-
                                                        .......                     .. ...... ||..| 
--------------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKF

---MLTLDPSLRFS-ADECLQHEFF
   ||  ||. |.. ....|.|..|
GKRMLQKDPEKRITGWEQILNHPWF
Kinase 26699.AA CDC2 92-284 33 1.5e-42 128.24 In-house 15-211 (301) Show / Hide 
Range on Protein: 92-284
Range on HMM: 15-211/301
Sequence Identity: 33% (69 aa)

VYKARRKVDQKIVALKKIIEESPSPS--------QGMNILKRLDTHPNLVKLLDIVIEKDANLTTSTFFVFEYCEHDLEGMFL----SKIRFNLPQIKRV
|||.. . ...|||||||  |. .              .|| |. |||.||| |....       . . ||||...||         ..  . .  .|  
VYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ------NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSY

IHSILMGLSELQKKNIIHRDIKTDNILYNKNREIKVADFGLSKDLNIKRAPLS--KKLQNIFYRAPESLLGSQHYSFKVDIWCAGIIFYQLLFRNQENVT
.. || |.. .  . |.|||.| .||| .|. .||.|||||... .|   ..   .      ||||| |||...||. ||.|  | ||. . .     ||
MYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMD----VT

YKALFAA
 |.||..
KKPLFHG
Kinase 26699.AA CRK7 122-252 40 9.2e-32 106.67 In-house 54-192 (343) Show / Hide 
Range on Protein: 122-252
Range on HMM: 54-192/343
Sequence Identity: 40% (57 aa)

ILKRLDTHPNLVKLLDIVIEK----DANLTT-STFFVFEYCEHDLEGMFLSK-IR-FNLPQIKRVIHSILMGLSELQKKNIIHRDIKTDNILYNKNREIK
||. |. |.| |.| .||..|    . . .  |.. ||||  ||| |  .|| .  |.. |.|     .| |.  . |||..|||||  |||.| . |.|
ILRQLN-HQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGLLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVK

VADFGLSKDLNI--KRAPLSKKLQNIFYRAPESLLGSQHY
 |||||   .|   ||.|.  .     ||.|| ||| ..|
IADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERY
Kinase 26699.AA ULK 92-270 26 1.2e-31 107.78 In-house 15-251 (329) Show / Hide 
Range on Protein: 92-270
Range on HMM: 15-251/329
Sequence Identity: 26% (65 aa)

VYKARRKVD----QKIVALKKII--EESPSP--------SQGMN----ILKRLD-------THPNLVKLLDIVIEKDA-NLTTSTFFVFEYCEH-DLEGM
|||.| | .    ...|| |.|   ... ..         |  .    |.|.|.       .||| |||.|.  ...  |.    ....|||.. |||  
VYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNI----YIIMEYCNGGDLEQY

FLSKIRFNLPQ----------IKRVIHSILMGLSELQKKNIIHRDIKTDNILYNKNR------------EIKVADFGLSKDLNIK--RAPLSKKLQN---
   . ......          .. ... || |. ||.|.|||||||| .||| ...              .|.||||..| ..     . . .   |   
IKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKR

----IFYRAPESLL----GSQHYSFKVDIWCAGIIFYQLLF
      | ||. |     . ..|..|.|||  |.|||..|.
LCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLY
Kinase 26699.AA ULK 92-270 26 1.4e-31 109.35 In-house 16-247 (324) Show / Hide 
Range on Protein: 92-270
Range on HMM: 16-247/324
Sequence Identity: 26% (62 aa)

VYKARRKVD---QKIVALKKII--EESPSPSQ--------GMN----ILKRLD--THPN--LVKLLDIVIEKDANLTTSTFFVFEYCEH-DLEGMFLSK-
|||.| | .   ...|| |.|   . . ....          .    |.| |.   |||   |||.|.  ...    . .....|||.. |||     . 
VYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNH---NNIYIIMEYCNGGDLEQYIKKNK

--------IRFNLPQIKRVIHSILMGLSELQKKNIIHRDIKTDNILYNKNR------------EIKVADFGLSKDLNIKRAPLSKKLQNI---------F
         |.. .... ... |. |. ||.|.|||||||| .||| ...              .|.||||..| ..       .  .            
KLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPL

YRAPESLL----GSQHYSFKVDIWCAGIIFYQLLF
| ||. |     . ..|..|.|||  |.|||..|.
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLY
Kinase 26699.AA Ciliate-E2-Unclassified 92-270 23 1.5e-30 103.24 In-house 15-265 (352) Show / Hide 
Range on Protein: 92-270
Range on HMM: 15-265/352
Sequence Identity: 23% (60 aa)

VYKARRKVDQ-----------KIVALKKIIEESPSPSQGMNILKRLD----------------THPNLVKLLDIVIEKDANLTTSTFFVFEYCEHDLEGM
|||...| ..           .|.. |.| ..    .. |......                  ||..... .. ...| .     ..| ||||.     
VYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN---IYIVMEYCEGGDLWQ

FLSK------------------IRFNLPQIK-----RVIHSILMGL-SELQKKNIIHRDIKTDNILYNKNR---EIKVADFGLSKDL-------------
...|                   .|   |.|     . .  || || .  .|.|||||||| .|||...|    .||..|||.|| .             
YIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQK

--NIKRAPLSKKLQNIFYR----APESLLGSQHYS---FKVDIWCAGIIFYQLLF
  ..|.  .. . ... |     ||| | | ...    .|.|||. |.|.|..||
MQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLF
Kinase 26699.AA CAMK 120-266 18 2e-28 88.11 In-house 82-325 (425) Show / Hide 
Range on Protein: 120-266
Range on HMM: 82-325/425
Sequence Identity: 18% (46 aa)

MNILKRLDT------HPNLVKLLDIVIEKDA--------NLTT-------STFFVF---EYCEH-----DLEGMFLSK---------------IRFNLPQ
..|.|.|        |||..||...   ..         . ..         ..|.   |||.      ||  .  ..                ||.  .
IEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTERE

IKRVIHSILMGLSELQKKNIIHRDIKTDNILYNKN-----------------REIKVADFGLSKDLNIK-----------------------RAPLSKKL
 .|... |. ..  . ..||.|||.| .|||...|                   ||..|||... .. .                         ...   
ARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFC

QNIFYRA-PESLLG-------------SQHYSFKVDIWCAGIIFY
    | | || |.|              . |..|.|.| .|.| |
GTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILY
Kinase 26699.AA PITSLRE 121-265 35 1.8e-26 93.48 In-house 66-211 (295) Show / Hide 
Range on Protein: 121-265
Range on HMM: 66-211/295
Sequence Identity: 35% (53 aa)

N-ILKRLDTHPNLVKLLDIVIEKDANLTTSTFFVFEYCEHDLEGMFLSKIR-----FNLPQIKRVIHSILMGLSELQKKNIIHRDIKTDNILYNKNREIK
| ||. |  ||| |... ||. .. .   . . |.|| |||| .. . ...     | ...||  .   | | . .... |.||| || |.||. .   |
NMILMAL-QHPNIVNVKEIVMGSNMD---KIYMVMEYVEHDLKSL-MENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILK

VADFGLSKDLNIKRAPLSKKLQNIFYRAPESLLGSQHYSFKVDIWCAGIIF
..||||       . |...      ||||| |||.. ||  ||.|  | ||
ICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIF
Kinase 26699.AA CRK7 339-383 48 2.6e-14 45.58 In-house 301-343 (343) Show / Hide 
Range on Protein: 339-383
Range on HMM: 301-343/343
Sequence Identity: 48% (22 aa)

NRFIEHLKGINPNVDDSALDLLSKMLTLDPSLRFSADECLQHEFF
. |..| |    . .  .|||| |||.|||. ||.| |||||..|
EEFYHHKKPV--FMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 26699.AA CAMK 349-383 34 3.7e-14 41.31 In-house 392-425 (425) Show / Hide 
Range on Protein: 349-383
Range on HMM: 392-425/425
Sequence Identity: 34% (12 aa)

NPNVDDSALDLLSKMLTLDPSLRFSADECLQHEFF
. .|.... ||..|||. ||. |.....||.|...
H-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 26699.AA Pkinase_Tyr 92-259 26 1.4e-13 46.67 Pfam 15-198 (270) Show / Hide 
Range on Protein: 92-259
Range on HMM: 15-198/270
Sequence Identity: 26% (50 aa)

VYKARRK----VDQKIVALKKIIEESPSPS-------QGMNILKRLDTHPNLVKLLDIVI-EKDANLTTSTFFVFEYCEH-DLEGMFLS----KIRFNLP
|||.. |     ..  || |.. | . ..        . ..|.| |  |||.|.|. ... ... |   . . |.||..| ||     .    | .....
VYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDYLRKHREDKQPLTMK

QIKRVIHSILMGLSELQKKNIIHRDIKTDNILYNKNREIKVADFGLSKDLNIKRAPLS-KKLQ----NIFYRAPESLLGSQHYSFKVDIW
..    . | .|.. |  ||.||||. . |.| ..|. .|..||||..|.         .| .     |.  |||..  .  .. | |.|
DLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVW
Kinase 26699.AA CDC2 345-383 41 1.9e-13 37.15 In-house 254-301 (301) Show / Hide 
Range on Protein: 345-383
Range on HMM: 254-301/301
Sequence Identity: 41% (20 aa)

LKGINPN---------VDDSALDLLSKMLTLDPSLRFSADECLQHEFF
|. | ||         .|. ..|||..|| .||. | ||.| ||| .|
LSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 26699.AA PITSLRE 352-383 40 2.8e-12 41.21 In-house 264-295 (295) Show / Hide 
Range on Protein: 352-383
Range on HMM: 264-295/295
Sequence Identity: 40% (13 aa)

VDDSALDLLSKMLTLDPSLRFSADECLQHEFF
. | ..||| .|||..|  |..|.. |.|..|
ISDTGFDLLNQMLTYNPKNRITASDALKHPWF
TyrKc 26699.AA TyrKc 85-383 19 8.4e-11 -48.01 SMART 1-280 (280) Show / Hide 
Range on Protein: 85-383
Range on HMM: 1-280/280
Sequence Identity: 19% (68 aa)

VLLINRL-------VYKARRKVDQKIVALKKIIEESPSPSQGM----NILKRL-DTHPNLVKLLDIVIEKDANLT---TSTFFVFEYCEH-DLEGMFLSK
. |.  |       |||.. |     || |.. |..    . .    .|...|   |||.|.|. .....  |        . |.||..| ||   .| |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKD-YLRK

IR--FNLPQIKRVIHSILMGLSELQKKNIIHRDIKTDNILYNKNREIKVADFGLSKDL----------NIKRA---PLSKKLQNIFYRAPESLLGSQHYS
 |  .....     . |  | . | .||.||||. . |.|...|. .|..|||||.|.            .|.     .| .  |   |||..     ..
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

FKVDIW---------CAGIIFYQLL-----FRNQENVTYKALFAANFDEQLKQ----AKNYFSLLGNPENENIWSQNSKNELKMKDYDAVLSQITPEEKA
.| |.|         .                |||   .. . . .  .| .     .                                          
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQE--VIEYVKQGYRMPQPPNDYPMS------------------------------------------

NFKNRFIEHLKGINPNVDDSALDLLSKMLTLDPSLRFSADECLQHEFF
     |        .   |   .. ..    ||. | .  |.  ||.|
-----F--------VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 26699.AA Ciliate-E2-Unclassified 348-383 27 1.5e-08 25.85 In-house 313-352 (352) Show / Hide 
Range on Protein: 348-383
Range on HMM: 313-352/352
Sequence Identity: 27% (11 aa)

INPNVDDSALDLLS----KMLTLDPSLRFSADECLQHEFF
|  .....| |...    |||  .|. | .... |.| .|
IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 26699.AA ULK 349-383 31 1.4e-05 15.53 In-house 295-329 (329) Show / Hide 
Range on Protein: 349-383
Range on HMM: 295-329/329
Sequence Identity: 31% (11 aa)

NPNVDDSALDLLSKMLTLDPSLRFSADECLQHEFF
.|.. .   ||...||. |.. |.| .| ..|..|
DPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 26699.AA ULK 349-383 31 9.4e-05 12.86 In-house 290-324 (324) Show / Hide 
Range on Protein: 349-383
Range on HMM: 290-324/324
Sequence Identity: 31% (11 aa)

NPNVDDSALDLLSKMLTLDPSLRFSADECLQHEFF
.|.. .   ||...||. |.. |.| .| ..|..|
DPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 26699.AA CRK7 92-110 52 0.006944 5.55 In-house 15-33 (343) Show / Hide 
Range on Protein: 92-110
Range on HMM: 15-33/343
Sequence Identity: 52% (10 aa)

VYKARRKVDQKIVALKKII
||||. |   ..|||||..
VYKAKNKHTGEMVALKKVR