Gene 12019 (Tetrahymena)
12019
Group:
Other
Family:
Ciliate-E1
Sequence
Protein domains of 12019.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 12019.AA | Ciliate-E1 | 2-134 | 21 | 6.8e-21 | 65.02 | In-house | 52-202 (202) | Show / Hide |
Range on Protein: 2-134 Range on HMM: 52-202/202 Sequence Identity: 21% (32 aa) KNFNSTIQLFDCFDLDELKTFILITESINQTFYDYIQ--------NMYSSSLIEPDFGEVVNIFQSLLFSLFEIHSKGFYHLNINPHSIVFDQSGNLKFR |. ..||..|....|.....|.|.|. .....||.| ..... .. .| ....|. |.. | |.|.....|..|.|. |.....||... KKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYC -----NFLNFNELNYFETSKMIKDPYYSFF-N----SPEADQIIPKTLNIY ||. |.... . ... |.. | ... .|.| . ..|| DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY |
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Kinase | 12019.AA | Ciliate-B2 | 54-95 | 28 | 2e-05 | 8.63 | In-house | 107-148 (197) | Show / Hide |
Range on Protein: 54-95 Range on HMM: 107-148/197 Sequence Identity: 28% (12 aa) VNIFQSLLFSLFEIHSKGFYHLNINPHSIVFDQSGNLKFRNF .... |. | ..... || |.| | | |.|| .. .| YQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDF |
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TPR | 12019.AA | TPR | 283-316 | 17 | 0.054219 | 11.71 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 283-316 Range on HMM: 1-34/34 Sequence Identity: 17% (6 aa) YSLMYEIGIFYYESDNVQKCLDLFKQTLLIRQNL . | .| || . ..... ... | . | AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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TPR_2 | 12019.AA | TPR_2 | 283-316 | 17 | 0.20927 | 9.06 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 283-316 Range on HMM: 1-34/34 Sequence Identity: 17% (6 aa) YSLMYEIGIFYYESDNVQKCLDLFKQTLLIRQNL . | .| ||. . .. ...... | . | AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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TPR_1 | 12019.AA | TPR_1 | 283-316 | 20 | 0.744734 | 6.97 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 283-316 Range on HMM: 1-34/34 Sequence Identity: 20% (7 aa) YSLMYEIGIFYYESDNVQKCLDLFKQTLLIRQNL . | .| ||. | .. .. ... | .. | AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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TPR | 12019.AA | TPR | 325-358 | 26 | 0.000249 | 21.63 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 325-358 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) SESYNSVGNSNYYLDNFQEALQFYEKSCNLRKEL .| .. ||. | . ...||...|.|. | . AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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TPR_2 | 12019.AA | TPR_2 | 325-358 | 26 | 0.000316 | 19.04 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 325-358 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) SESYNSVGNSNYYLDNFQEALQFYEKSCNLRKEL | .. |.. |.. ...||...|||. | . AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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TPR_1 | 12019.AA | TPR_1 | 325-358 | 29 | 0.000671 | 17.6 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 325-358 Range on HMM: 1-34/34 Sequence Identity: 29% (10 aa) SESYNSVGNSNYYLDNFQEALQFYEKSCNLRKEL .| .. || | . |..||...|.| |. . AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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TPR | 12019.AA | TPR | 367-400 | 20 | 0.072523 | 10.6 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 367-400 Range on HMM: 1-34/34 Sequence Identity: 20% (7 aa) SECFTNIADCYRWLNNVEMSIQFNQLAIDIQNKT .|.. |.. ||. ... .. |.. | |.... . AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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TPR_1 | 12019.AA | TPR_1 | 367-400 | 23 | 0.201724 | 8.95 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 367-400 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) SECFTNIADCYRWLNNVEMSIQFNQLAIDIQNKT .| ..|.. ||. ..| . |.. | |.... . AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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TPR_2 | 12019.AA | TPR_2 | 367-400 | 17 | 59.254593 | 0.38 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 367-400 Range on HMM: 1-34/34 Sequence Identity: 17% (6 aa) SECFTNIADCYRWLNNVEMSIQFNQLAIDIQNKT |. |...||. ... . |.. . |. . . AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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TPR | 12019.AA | TPR | 409-442 | 8 | 0.051182 | 11.93 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 409-442 Range on HMM: 1-34/34 Sequence Identity: 8% (3 aa) IFSLICMGQIARWKNNHQKSLEYHLQVLKMREDI . . ..|.. . ...... .|. ..|.. .. AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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TPR_1 | 12019.AA | TPR_1 | 409-442 | 11 | 0.478692 | 7.64 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 409-442 Range on HMM: 1-34/34 Sequence Identity: 11% (4 aa) IFSLICMGQIARWKNNHQKSLEYHLQVLKMREDI . .|.. . ..|... .|. ..|..... AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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TPR_2 | 12019.AA | TPR_2 | 409-442 | 17 | 0.497254 | 7.73 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 409-442 Range on HMM: 1-34/34 Sequence Identity: 17% (6 aa) IFSLICMGQIARWKNNHQKSLEYHLQVLKMREDI . ..||... ...... .|| ..|| .. AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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TPR | 12019.AA | TPR | 451-484 | 26 | 0.000327 | 21.24 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 451-484 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) PLSYRTIGICYKYLKDYEKSFEYHKKALLMKQEI . . .| || ..||.. |. .||| . . AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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TPR_1 | 12019.AA | TPR_1 | 451-484 | 23 | 0.000765 | 17.4 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 451-484 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) PLSYRTIGICYKYLKDYEKSFEYHKKALLMKQEI . . .| || ...|.. |. .||| . . AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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TPR_2 | 12019.AA | TPR_2 | 451-484 | 29 | 0.005954 | 14.53 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 451-484 Range on HMM: 1-34/34 Sequence Identity: 29% (10 aa) PLSYRTIGICYKYLKDYEKSFEYHKKALLMKQEI . .. .| || ...||.. || .||| . AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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TPR_1 | 12019.AA | TPR_1 | 493-510 | 33 | 15.992287 | 2.32 | Pfam | 1-18 (34) | Show / Hide |
Range on Protein: 493-510 Range on HMM: 1-18/34 Sequence Identity: 33% (6 aa) ANSFFDLADCYLGIQDYD |. .. |. ||. ..|| AEAWYNLGNCYYKMGNYD |
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TPR_2 | 12019.AA | TPR_2 | 493-510 | 38 | 31.352345 | 1.36 | Pfam | 1-18 (34) | Show / Hide |
Range on Protein: 493-510 Range on HMM: 1-18/34 Sequence Identity: 38% (7 aa) ANSFFDLADCYLGIQDYD | . |..||. .||| AEAWYNLGQCYYKQGDYD |