Gene 13476 (Tetrahymena)

13476

Species: Tetrahymena
Alias: 13476, 1138, PreTt13476, 38.m00311, TTHERM_00367560
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
13476.AA Protein None 735 None Fasta, JSON
13476.kin_dom Protein Kinase Domain None 86 None Fasta, JSON
13476.NA RNA None 2208 None Fasta, JSON

Protein domain

Protein domains of 13476.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13476.AA Ciliate-A8 33-194 41 2e-47 161.51 In-house 1-151 (151) Show / Hide 
Range on Protein: 33-194
Range on HMM: 1-151/151
Sequence Identity: 41% (70 aa)

YIYEREISKGHFNIVVQAKSANNHNCKVAIKILNY-EYNSKINVEKLNKQIDFQDSLSEEKYILKFIQLIQDQKYGFTAIITEYCEG--FYSNNQQYHQK
|.|.. . || | .||||.|  ||.|.|||||..| .   ||| ....|.|     .  |||||..|. ||| ..||.||.||.|.   ||         
YKYQKVLEKGDFSYVVQAYSI-NHQCQVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCDCFDFYK--------

LKFSNIKYKATLAQVLE--QNNLTITQVYALAYQLIKGLILLQEKDKVLKYIEPNKIFYSISKNQFL
        | .||..||   |..|. |..||.|||.|.|...|||. ... | |. |.|| |||||.
-------KKENLASILENNLNKFTFEQIVALTYQLLKCLLVFQEKGIIHCDIKPQNILYSWSKNQFI
Kinase 13476.AA Ciliate-E1 39-196 26 7.7e-24 74.71 In-house 1-151 (202) Show / Hide 
Range on Protein: 39-196
Range on HMM: 1-151/202
Sequence Identity: 26% (42 aa)

ISKGHFNIVVQAKSANNHNCKVAIKILNYEYN-SKINVEKLNKQID-FQDSLSEEKYILKFIQLIQDQKYGFTAIITEYCEGFYSNNQQYHQKLKFSNIK
|..|.| ||..||. ||....||.|| |...| .... ....|... ... . .|.||...|. |..... ...||.|.|.  . ...|.|      | .
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNH------N-R

YKATLAQVLEQNNLTITQVYALAYQLIKGLILLQEKDKVLKYIEPNKIFYSISKNQFLLS
 .    .  .||..|..|. ....|||.||| |. .      | | .| .. . ......
LEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYC
Kinase 13476.AA S_TKc 33-266 11 1.8e-05 -96.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 33-266
Range on HMM: 1-231/231
Sequence Identity: 11% (34 aa)

YIYEREISKGHFNIVVQAKSANNHNCKVAIKILNYEYNSKINVEKLNKQIDFQDSLSEEKYILKFIQLIQDQKYGFTAIITEYCEG----FYSNNQQYHQ
|   |.| || |  | ...  .  . .|||||..         |.. . |.   .    ..| |..  .||   ..  ...|||.|     ..  ...  
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

KLK---FSNIKYKATLAQVLE------QNNLT----------------------------------------ITQVYA----------LAYQLIKGLILL
. .   |.    .  ..|...      ...                                          . .             . | .. |  . 
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPF

QEKDKVLKYIEPNKIFYSISKNQFLLSVILLEALLQRKLKGMEYLNLKTQNLISVFPDLPNQYNDEFVTKVLSKMVEPNLSKRSYPLSLLQ-----ELNK
.         .....|  |                                             .|.    ..|. . . .||     .||      .  
P---------QMQMMFKKIG-------------------------------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHP

FK
. 
WF
Kinase 13476.AA AGC 33-99 14 3.9e-05 7.66 In-house 1-78 (395) Show / Hide 
Range on Protein: 33-99
Range on HMM: 1-78/395
Sequence Identity: 14% (12 aa)

YIYEREISKGHFNIVVQAKSANNH-----NCKVAIKILNYEY-NSKIN--VEKLNKQI-------DFQDSLSEEKYILKFIQ
.   . |.||.|  | ...  ...     .   |.|.|. ..   ...   .. ..         .    . ||. ||. ..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGY----VWEERNILEKCN
Kinase 13476.AA Dicty3-Unclassified 33-94 29 9.1e-05 11.89 In-house 1-55 (252) Show / Hide 
Range on Protein: 33-94
Range on HMM: 1-55/252
Sequence Identity: 29% (18 aa)

YIYEREISKGHFNIVVQAKSANNHNCKVAIKILNYEYNSKINVEKLNKQIDFQDSLSEEKYI
.. || .||| |  .  |.  |  |  ..||| .|    .. .    |.||. | .   |..
WVIERQLSKGSFSQIYKAHKKNDPNFICNIKIIQYC---MFTM----KKIDYDDKIQFNKFV
Kinase 13476.AA CMGC 33-65 19 0.000137 9.98 In-house 1-46 (513) Show / Hide 
Range on Protein: 33-65
Range on HMM: 1-46/513
Sequence Identity: 19% (9 aa)

YIYEREISKGHFNIVVQAKSANNH-------------NCKVAIKIL
|   . | .|.. .|....  ..              | .||||..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKI
Kinase 13476.AA ULK 33-118 23 0.000203 11.44 In-house 1-104 (329) Show / Hide 
Range on Protein: 33-118
Range on HMM: 1-104/329
Sequence Identity: 23% (24 aa)

YIYEREISKGHFNIVVQAKSANNH---NCKVAIKILNYEYNSKINVE--------KLNKQIDFQDSLSEE---KY----ILKFIQLIQDQKYGFTAIITE
|.  ... || |  | ...  ...   | |||.|..  .. ...| |         |.. |. .  |  .   |.    | |..   .....  . ||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCEG
||.|
YCNG
Kinase 13476.AA RTKL 33-65 41 0.000242 6.87 In-house 1-34 (259) Show / Hide 
Range on Protein: 33-65
Range on HMM: 1-34/259
Sequence Identity: 41% (14 aa)

YIYEREISKGHFNIVVQAKSANNHNC-KVAIKIL
 | | |  .| |  |.||.|       .|||||.
FILENELGRGQFSRVYQARSCSRMVPTQVAIKIA
Kinase 13476.AA ULK 33-118 22 0.000268 11.23 In-house 1-101 (324) Show / Hide 
Range on Protein: 33-118
Range on HMM: 1-101/324
Sequence Identity: 22% (23 aa)

YIYEREISKGHFN-IVVQAKSANNH--NCKVAIKILNYEYNSKINVE--------KLNKQIDFQDSLSE--EKY--ILKFIQLIQDQKYGFTAIITEYCE
|.  ... || |   | ...  ...  | .||.|. .  . .|.. |        .|.. |  .  | |   ..  | |..   ... . .. ||.|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

G
|
G
Kinase 13476.AA CAMK1 33-91 24 0.000301 8.18 In-house 1-55 (276) Show / Hide 
Range on Protein: 33-91
Range on HMM: 1-55/276
Sequence Identity: 24% (15 aa)

YIYEREISKGHFNIVVQAKSANN--HNCKVAIKILNYEYNSKINVEKLNKQIDFQDSLSEE
|.   || .| | .|....  ..   . ..|||...     | ...| . |   |..|  |
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK----KKFMKKKDMQ-K-QEALENE
Kinase 13476.AA PDK1 33-66 27 0.000337 8.19 In-house 1-37 (307) Show / Hide 
Range on Protein: 33-66
Range on HMM: 1-37/307
Sequence Identity: 27% (10 aa)

YIYEREISKGHFNIVVQAKSANNH---NCKVAIKILN
.| ...| .| . .|. |..  .    | ..||||..
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICE