Gene 23445 (Tetrahymena)

23445

Species: Tetrahymena
Alias: PreTt23445, TTHERM_01370770, 352.m00004, 1033, 23445
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
23445.AA Protein None 999 None Fasta, JSON
23445.kin_dom Protein Kinase Domain None 27 None Fasta, JSON
23445.NA RNA None 3000 None Fasta, JSON

Protein domain

Protein domains of 23445.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 23445.AA Ciliate-E1 77-250 22 1e-21 67.7 In-house 1-202 (202) Show / Hide 
Range on Protein: 77-250
Range on HMM: 1-202/202
Sequence Identity: 22% (46 aa)

IKSGGEADIFK---NQNN-DSIAYRIIKLN---GDDDLRKQEKELLRIQELQEQNILNIDSSHLIEDKANHTRYIINSMQKCQMSLYDEIS---------
|..|.....||   ..||  ..|  ||...    .... .. ||   |..  ....  |.    |... | . .||  ...|..||.|...         
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIII--FECCCCSLKDYLQNHNRLEYWQ

----KNKVFNLRETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQ-----QVDFIDPFCDYQMHTDGYKPQ------DREKNLPF
    ... |.  . .. |  ... || |.|. |.|.|||| |||. ...||...||| |.     | . .. ..  ..    .. .      .....  .
QCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINY

YHDIY
  |||
KSDIY
Kinase 23445.AA Ciliate-B2 148-215 38 6.4e-21 45.85 In-house 80-151 (197) Show / Hide 
Range on Protein: 148-215
Range on HMM: 80-151/197
Sequence Identity: 38% (28 aa)

MQKCQMSLYDEIS---KNK-VFNLRETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGAS
|.||. || .|.    | .  ||    .. |   .  || .| . | | |||| |||.   .||...||| |
MEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGIS
Kinase 23445.AA Ciliate-C6 150-219 37 1.2e-11 37.51 In-house 117-188 (306) Show / Hide 
Range on Protein: 150-219
Range on HMM: 117-188/306
Sequence Identity: 37% (27 aa)

KCQMSLYDEISKNKVFNLRETLKFISTAFHLLIVLRQ-KYIYHSDIKPGNILKIDD-NNYKLSDFGASQQVD
| .....    | . |.  | ..| .    .|  ..    | | |||| ||| .|| |||.|||||..|| .
KQEINIFSFNYKYEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQQLF
Kinase 23445.AA Ciliate-E3 181-217 51 2.1e-08 22.63 In-house 116-155 (202) Show / Hide 
Range on Protein: 181-217
Range on HMM: 116-155/202
Sequence Identity: 51% (21 aa)

LIVLRQKYIYHSDIKPGNILKIDDNN----YKLSDFGASQQ
.| . .| | |||||| ||| .| ||     | .|||.| |
MIAIHEKNIIHSDIKPDNIL-VDKNNNQLIIKICDFGESKQ
Kinase 23445.AA S_TKc 71-322 16 3.9e-08 -57.67 SMART 1-231 (231) Show / Hide 
Range on Protein: 71-322
Range on HMM: 1-231/231
Sequence Identity: 16% (46 aa)

FKLGDHIKSGGEADIFKNQNND---SIAYRIIKLNGDDDLRKQEKELLRIQELQEQNILNIDSSHLIEDKANHTRYIINSMQKCQM---SLYDEISKNKV
......| .|. .  .| ....     |  |||     .  ..| ..|.    .  || ..  .        .  |..  |  |     .|.| | |.. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK---HHPNIVKLYDVFQD-----DHLYMV--MEYCDGDLGDLFDYIKKRGR

------FNLRETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQQVDFIDPFCDYQMHTDGYKPQDREKNLPFYH---DIYSFGKT
      |.  .. ...   .  |  . .. | | |.|| ||| .|. . |..||| . |.       . .  |  | .       .. .   |..|.| .
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENIL-LDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

IQKLLM------QLGNCSEKISDCLKEFIKEEICKDDENSINVDCFELPIKFINKIMKFTND---GVIDVFL-------EEYL
.  .|       |.    .||                         .  . ||.|....  .   .. ...         ...
LYEMLCGYPPFPQMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 23445.AA Ciliate-A1 127-226 23 1e-07 22.29 In-house 59-159 (301) Show / Hide 
Range on Protein: 127-226
Range on HMM: 59-159/301
Sequence Identity: 23% (24 aa)

NIDSSHLIEDKAN--HTRYIINSMQKCQMSLYDEISKNKV-FNLRETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQQVDFIDP
.| .  ..... |     .||  | .||  .  .  ...      |   . .  .  .. .  . | |.|.||.|||  .|. .|. |.| |.|  .   
VIKNYQQLYYNTNNKECMFII--MEYCQYGNLFNYCYQNDYMKKEEIYEICYQIIEGYADIHDHNILHRDLKPQNILIHFDDKWKICDLGMSKQLEQNQD

FCD
 ||
CCD
Kinase 23445.AA DYRK2 152-215 35 5e-07 18.55 In-house 84-151 (318) Show / Hide 
Range on Protein: 152-215
Range on HMM: 84-151/318
Sequence Identity: 35% (24 aa)

QMSLYDEISKNKV--FNLRETLKFISTAFHLLIVLRQKYIYHSDIKPGNIL--KIDDNNYKLSDFGAS
.|.||. | ||.   |.|..  .|.    . |  |..  | | | || |||  .   .. |. ||| |
SMNLYEYIKKNHFQGFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSS
Kinase 23445.AA LKB 189-224 41 1e-06 15.94 In-house 125-160 (265) Show / Hide 
Range on Protein: 189-224
Range on HMM: 125-160/265
Sequence Identity: 41% (15 aa)

IYHSDIKPGNILKIDDNNYKLSDFGASQQVDFIDPF
. | ||||||.|   ||  |..|||   |..   ..
VVHKDIKPGNLLLTHDNTLKICDFGVAEQLHHFQRD
Kinase 23445.AA MOK 189-227 43 3e-06 15.13 In-house 121-158 (283) Show / Hide 
Range on Protein: 189-227
Range on HMM: 121-158/283
Sequence Identity: 43% (17 aa)

IYHSDIKPGNILKIDDNNYKLSDFGASQQVDFIDPFCDY
|.| |.|| ||| | .   ||.|||.   |    |. .|
IFHRDVKPENIL-IKQDHLKLADFGSCRSVYSKQPYTEY
Kinase 23445.AA Ciliate-A5 180-213 38 9e-06 16.09 In-house 111-144 (275) Show / Hide 
Range on Protein: 180-213
Range on HMM: 111-144/275
Sequence Identity: 38% (13 aa)

LLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFG
.. .|.|. |.| ||.| ||.  .|. .|| |..
VCMYLQQNNICHGDIRPQNICLTQDGQVKLMDMN
Kinase 23445.AA KHS 71-137 25 1.1e-05 14.97 In-house 1-70 (258) Show / Hide 
Range on Protein: 71-137
Range on HMM: 1-70/258
Sequence Identity: 25% (18 aa)

FKLGDHIKSGGEADIFKNQNNDS---IAYRIIKLNGDDDLRKQEKELLRIQELQEQNILNIDSSHLIEDK
. |  .. ||   |..| ..  |    | ..||.. .||.    .|.. ... .  ||.    | | .||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDK
Kinase 23445.AA KHS 191-218 53 0.001979 7.25 In-house 119-146 (258) Show / Hide 
Range on Protein: 191-218
Range on HMM: 119-146/258
Sequence Identity: 53% (15 aa)

HSDIKPGNILKIDDNNYKLSDFGASQQV
| |||  |||  |. . || ||| | |.
HRDIKGANILLTDQGDVKLADFGVSAQI
Kinase 23445.AA Ciliate-A5 79-128 19 0.002369 7.59 In-house 1-51 (275) Show / Hide 
Range on Protein: 79-128
Range on HMM: 1-51/275
Sequence Identity: 19% (10 aa)

SGGEADIFKNQ-NNDSIAYRIIKLNGDDDLRKQEKELLRIQELQEQNILNI
 .|.  |.||| ..   ..  ....  | . . ....   ..|| .||...
FYGCMKIWKNQHQQEYYICKQKQIQDEDRQKHFQQYFEQRMQLQHPNIVKL