Gene 14827 (Tetrahymena)

14827

Species: Tetrahymena
Alias: 282.m00025, PreTt14827, 14827, 764, TTHERM_01227720
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2a

Sequence

Name Sequence Type Origin Length Description Download
14827.AA Protein None 731 None Fasta, JSON
14827.kin_dom Protein Kinase Domain None 273 None Fasta, JSON
14827.NA RNA None 2196 None Fasta, JSON

Protein domain

Protein domains of 14827.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 14827.AA Ciliate-E2a 234-511 41 1.6e-161 479.2 In-house 1-275 (275) Show / Hide 
Range on Protein: 234-511
Range on HMM: 1-275/275
Sequence Identity: 41% (121 aa)

YWLTLLLILHCVNKVYLVNLVGTNKHFAIKAFLKEKLIEEEKGYESFYNEIMLMRCIKNKNALKLIDIWESKNSYYLIMPVCYGGSLLDRIAFTKKIEKN
| .. ... .. ..|||... .|.|.||.|.| | |. ...||.|.|.|||..||.....| .||....|..|.|||.|  |.||.|.|.|   |.. ..
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

PELLMQSKANPIDSLFIKSFMKQML-EALLNLKQQGILHRDLKPDNILL--CSPNQ---VEPMIIDFGLATFQ--DVENYIYPKCGTPGYVAPEIINMRD
             .  |...|.|.| ..|....|..|.||||||.|||.  ||.|     . .|||||||||.  | ..|...|||||||||||..|...
-------------IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKE

--KSQRYDSQCDVFSLGAIFYFLLSLKPLFLGKVTKETIEMNKRCQIDFDCKE-LQNVDLNTKDLLKKLLKVNPSERITPEQALQHPYF
  |...|| .||..|.|.|||.||. ||.| || ..|....||.|.|||.|.| ........|||.||.|...|..|||..|||.||.|
VLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 14827.AA Ciliate-E2 234-511 26 7.6e-87 294.82 In-house 1-365 (365) Show / Hide 
Range on Protein: 234-511
Range on HMM: 1-365/365
Sequence Identity: 26% (102 aa)

YWLTLLLILHCVNKVYLVNLVGTNKHFA----------------IKAFLKEKLIEEEKGYESFYNEIMLMRCIK----------------NKNALKLIDI
| .  ..   .  .||...   ..| ||                 |...... | .... |.. .|| .||.|.                ..| .|... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

WE--SKNSYYLIMPVCYGGSLLD-----RIAFTKKIEKNPELLMQSKANPIDSLFIKSFMKQMLE---------------ALLNLKQQG-ILHRDLKPDN
..  ..|..||.|  | ||.|.|     .. ....||       . . ....   || .||| |.               ||  |.... |.|||.||.|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE-------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPEN

ILLCSPNQVEPMIIDFGLATFQDVE-----------NYIYPK----------------------CGTPGYVAPEIINMRD-----KSQRYDSQCDVFSLG
||.       . ||||||....| .           .|.. |                      ||||||.||||.|. .     |...|| .||..|||
ILF-------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG

AIFYFLLSLKPLFLGKVTKETIEMNKRCQIDFDCKE--------------LQNVDLNTKDLLKK----LLKVNPSERIT-PEQALQHPYF
 |.|..|. || |        .. .| |.|||.|.|               .......|||.||    .|...|..||| .||.|.||.|
VILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 14827.AA CAMK 209-511 19 2.7e-65 209.1 In-house 1-425 (425) Show / Hide 
Range on Protein: 209-511
Range on HMM: 1-425/425
Sequence Identity: 19% (90 aa)

KLGKGSFASVLIFDIYIFLKKTPATYWLTLLLILHCVNKVYLVNLVGTN------------KHFAIKAFLKEKLIE------------------------
.||.|||. |                               |.    |.            ...|||   |.|| .                        
TLGRGSFGKVK------------------------------LCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWR

EEKGYESFYNEIMLMRC-------IKNKNALKLIDIWES-------------------KNSYYLIM---PVCYGG----SLLDRIAFTKK-----IEKNP
..|  .....|| .|.        .. .| .||....|.                   .. .|..|     | ||     |.|.|   ..     .    
RPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFD----

ELLMQSKANPIDSLFIKSFMKQMLEALLNLKQQGILHRDLKPDNILLCSPN--------------QVE-PMIIDFGLATFQDVEN---------------
 ..   .   ..    . ...|...|.  . ...| ||||||.||||.. |              ..    |||||.|.. |  .               
QFDIV-ERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHN

---------YIYPKCGTPGYVA-PEIINM----------RDKSQRYDSQCDVFSLGAIFYFLLSLKPLFLGK-------------VTKETIEMNKRCQID
           .  ||||.|.| ||..|            .. . |. .||. |.| | |..|. .| | |.               .|. |. .... |
QWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYD

FDCKELQN--------------------VDLNTKDLLKKLLKVNPSERITPEQALQHPYF
|. ... .                    |.   |||..|.|.|.|..|.| ||.|.|| .
FPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
S_TKc 14827.AA S_TKc 204-511 26 7.9e-59 202.67 SMART 1-231 (231) Show / Hide 
Range on Protein: 204-511
Range on HMM: 1-231/231
Sequence Identity: 26% (83 aa)

YKAVRKLGKGSFASV-LIFDIYIFLKKTPATYWLTLLLILHCVNKVYLVNLVGTNKHFAIKAFLKEKLIEEEKGYESFYNEIMLMRCIKNKNALKLIDIW
|. .||.|||.|..| .  ..                                |....|||              |....|| ...  . .|  ||.|..
YEILRKIGKGAFGKVYKCRHKK-------------------------------TGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVF

ESKNSYYLIMPVCYG--GSLLDRIAFTKKIEKNPELLMQSKANPIDSLFIKSFMKQMLEALLNLKQQGILHRDLKPDNILLCSPNQVEPMIIDFGLATFQ
.. ...|..|  | |  |.|.|.|   ..  ..          |..   ....|.|...||  . ..||.||||||.||||..    . .|.|||||.. 
QD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR---------FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL

DVENYIYPKCGTPGYVAPEIINMRDKSQRYDS-QCDVFSLGAIFYFLLSLKPLFLGKVTKETIEMNKRCQIDFDCKELQNVDLNTKDLLKKLLKVNPSER
      .  |||| |.|||..        |.   ||. |.| |.| .|. .|.|      .  .| |..            .   ||...|.|...|..|
------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKR

ITPEQALQ-------HPYF
.|  .|||       ||.|
PTA-EALQDEWDIKCHPWF
Kinase 14827.AA Pkinase 247-511 28 4.2e-58 204.15 Pfam 14-293 (293) Show / Hide 
Range on Protein: 247-511
Range on HMM: 14-293/293
Sequence Identity: 28% (85 aa)

KVYLVNLVGTNKHFAIKAFLKEKLIEEEKGYESFY-NEIMLMRCIKNKNALKLIDIWESKNSYYLIMPVCYGG----SLLDRIAFTKKIEKNPELLMQSK
.||.   .||.| .|.| . |.  ....| .. .  .|| .|. .. .| ..|.|..|.|...|..|. | ||    .| |.|               ..
CVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-------------WR

ANPI--DSLFIKSFMKQMLEALLNLKQQGILHRDLKPDNILLCSPNQVEP----MIIDFGLATF--QDVENYIYPKCGTPGYVAPEIINMRDKSQRYDSQ
 ...  .   .|..|.|.|..|  . ..||.||||||.|||.   |. ..     |.||||| .         .  ||||.|.|||.|.   ..| |.. 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPK

CDVFSLGAIFYFLLSLKPLFLGK------VTKETIEMNKRCQIDFDCKELQNVD-----------------LNTKDLLKKLLKVNPSERITPEQALQHPY
.|..|.| |.| .|. .|.| |.        .. |.........||. .. ..                   . ||..|..|...|..|.|.||.||||.
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F
Kinase 14827.AA CAMK1 354-511 38 2.4e-52 150.42 In-house 114-276 (276) Show / Hide 
Range on Protein: 354-511
Range on HMM: 114-276/276
Sequence Identity: 38% (63 aa)

MKQMLEALLNLKQQGILHRDLKPDNILLCSP-NQVEPM--IIDFGLATFQDVEN-YIYPKCGTPGYVAPEIINMRDKSQRYDSQCDVFSLGAIFYFLLSL
||| |.|.  . ..|| |||||| |.|. .. .. . .  |.||||... | .. . .  ||||||||||...     . ||  ||..| | |.|.||  
MKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK-DKPYDKACDMWSIGVITYILLCG

KPLFLGKV-TKETIEMNKRCQIDFDCKELQN-VDLNTKDLLKKLLKVNPSERITPEQALQHPYF
 | | ..   .|  |..|.|...|. ..  | .|   ||..|..|.|.|..|.| ||.|.|| .
YPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 14827.AA Ciliate-E2-Unclassified 246-511 22 3.1e-44 151.33 In-house 13-352 (352) Show / Hide 
Range on Protein: 246-511
Range on HMM: 13-352/352
Sequence Identity: 22% (79 aa)

NKVYLVNLVGTNKHF-----AIKAFLKE-KLIEEEKGYESFY----NEIM-------------LMRCIKNKNALKLIDIWESKNSYYLIMPVCYGGSLLD
.|||..    ..  .     ..|.  .  |.|....  ...     |...             ... ... . .|.... ..|.  |..|  | ||.|..
GKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQ

RIAFTKK------------IEKNPELLMQSK---ANPIDSLFIKSFMKQMLEALLNLKQQG-ILHRDLKPDNILLCSPNQ-VEPMIIDFGLATFQDV---
 |   ||             ...     |.|   |        | ...| |..|  | ... |.|||.||.|||. . ..  .. |||||.. ...    
YIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKA--------KFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNN

-------------ENYIYPKCGTPGYV----APEIINMRDKSQRYDSQ----CDVFSLGAIFYFLLSLKPLFLGKVTKE----------------TIEMN
             .. .. .||||.|     |||..    ..| || .    ||..||| |.|..|  .. | ..  ..                 ..  
CDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL----QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KRCQIDFDCKEL----QNVDLNTKDLLK----KLLKVNPSERITPEQALQHPYF
| ..|.|.. .     .... . ||...    |.||.||..|||.||.|.||.|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 14827.AA CDPK 366-511 35 1.7e-41 125.21 In-house 121-271 (271) Show / Hide 
Range on Protein: 366-511
Range on HMM: 121-271/271
Sequence Identity: 35% (55 aa)

QQGILHRDLKPDNILLCSPNQV-----EPMIIDFGLATFQDVE-----NYIYPKCGTPGYVAPEIINMRDKSQRYDSQCDVFSLGAIFYFLLSLKPLFLG
...| |||||| |||..| .       .  .||.|... .| .     .... .|||| |.|||...     ..|. .||. |.| | | ||.  | | |
SNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQ-----KKYNEKCDIWSCGVILYILLCGYPPFYG

KVTKETIEMNKRCQIDFDCKELQNVDLNTKDLLKKLLKVNPSERITPEQALQHPYF
|  .|..|. | .. .|. .| ...  . ||| .|.| ..|  |.. .||||||.|
KNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 14827.AA ULK 350-511 26 1e-36 125.7 In-house 132-329 (329) Show / Hide 
Range on Protein: 350-511
Range on HMM: 132-329/329
Sequence Identity: 26% (53 aa)

IKSFMKQMLEALLNLKQQGILHRDLKPDNILLCSPN----------QVEPMIIDFGLATFQDVEN-----YIYPK-----CGTPGYVAPEIINMR-DKSQ
...|.|| |...  | ...| |||.||.|||.  ..          ..   | |||.| . | .|     . . .     |||| | ||.|.. .  . .
AIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKP

RYDSQCDVFSLGAIFYFLLSLKPLFLGKVTKETI-----EMNKR--------CQIDFDCK---ELQNVDLNTKDLLKKLLKVNPSERITPEQALQHPYF
 ||. ||..||| ||| .|  || | .    ...     .  .         ... ....   . ...  ..|||....|......||. |. ..|| |
YYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 14827.AA CAMK-Unique 354-511 26 4.7e-36 116.36 In-house 163-363 (363) Show / Hide 
Range on Protein: 354-511
Range on HMM: 163-363/363
Sequence Identity: 26% (55 aa)

MKQMLEALLNLKQQGILHRDLKPDNILLCSP--------------NQVEPMIIDFGLATFQDVENYIYPK-----CGTPGYVAP--------------EI
| . |.|.  . .|.| |||||..||..|..              ..    ..||||..  .... . .      |||| |.||              |.
MQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCC--HYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEV

INMRDKSQRYDSQC----DVFSLGAIFYFLLSLKPLFLGKVTK--------ETIEMNKRCQI-DFDCKELQN---VDLNTKDLLKKLLKVNPSERITPEQ
|||    |.||.||    |  |||.| |..|. .| | . . .        |..|  . ... .|| |  .    .  . ||..|....| |. |.. ..
INM----QCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKE

ALQHPYF
.|.|...
LLEHQWI
Kinase 14827.AA ULK 350-511 26 6.9e-35 121.24 In-house 128-324 (324) Show / Hide 
Range on Protein: 350-511
Range on HMM: 128-324/324
Sequence Identity: 26% (52 aa)

IKSFMKQMLEALLNLKQQGILHRDLKPDNILLCSPN----------QVEPMIIDFGLATFQDVE----NYIYPKC------GTPGYVAPEIINMR-DKSQ
...|.|| ....  | ...| |||.||.|||.  ..          ..   | |||.| . | .    . ..  .      ||| | ||.|.. .  . .
AIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKP

RYDSQCDVFSLGAIFYFLLSLKPLFLGKVTKETI----EM----------NKRCQIDFDCK-ELQNVDLNTKDLLKKLLKVNPSERITPEQALQHPYF
 ||. ||..||| ||| .|  |. | .    ...    ..           |  .|.|. . . ...  ..|||....|......||. |. ..|| |
YYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 14827.AA RSK 366-511 30 1.2e-34 121.48 In-house 122-278 (278) Show / Hide 
Range on Protein: 366-511
Range on HMM: 122-278/278
Sequence Identity: 30% (49 aa)

QQGILHRDLKPDNILLCS---PNQVEPMIIDFGLATFQDVE--NYIYPKCGTPGYVAPEIINMRDKSQR-YDSQCDVFSLGAIFYFLLSLKPLFLG---K
|||| ||||||.|||. .   .  .  ...|||..   . .  .  .  |.|  |.|||...  .  |. .| .||..|||.. | .|. .| | |   .
QQGIIHRDLKPENILYDDESNEGHI--KLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDN

VTKETIEMNKRCQIDFDCKELQNVDLNTKDLLKKLLKVNPSERIT-----PEQALQHPYF
  ||...  ........ .. |..  . |||..|.|...|. |..      |. .|||.|
NRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 14827.AA CAMK1 247-324 34 1.2e-20 56.72 In-house 14-99 (276) Show / Hide 
Range on Protein: 247-324
Range on HMM: 14-99/276
Sequence Identity: 34% (30 aa)

KVYLVNLVGT---NKHFAIKAFL-KEKLIEEE--KGYESFYNEIMLMR-C--IKNKNALKLIDIWESKNSYYLIMPVCYGGSLLDRI
.|||..   |   .|..|||..  |. . ...  |  |...|||  |. .  |.  |  |.... ||.| .||.|  . || |.|||
EVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI
Kinase 14827.AA TyrKc 204-511 15 6.6e-11 -46.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 204-511
Range on HMM: 1-280/280
Sequence Identity: 15% (55 aa)

YKAVRKLGKGSFASVLIFDIYIFLKKTPATYWLTLLLILHCVNKVYLVNLVGTNKHFAIKAFLKEKLIEEEKGYESFYNEIMLMRCI--KNKNALKLIDI
 .  .||| | |  |     .                                    |.|   ...        | |..|. .|. .  ...| ..|. .
ITLGKKLGEGAFGEVYKGTWK---------------------------------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGV

WESK-------NSYYLIMPVCYGGSLLDRIAFTKKIEKNPELLMQSKANPIDSLFIKSFMKQMLEALLNLKQQGILHRDLKPDNILLCSPNQVEPMIIDF
  ..         ....|  . .|.|.|..  ...               .      ||. |  .    | .... ||||   |.|. ....|   | ||
CTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVK--ISDF

GLATFQDVE-------NYIYPKC--GTPG-----YVAPEIINMRDKSQRYDSQCDV----------FSLGAIFYFLLSLKPLFLGKVTKETIEMNKRCQI
||. . . .        |. .|   |. .       ||| |    .  .. .. ||          |..|.  |    ..     .   | ..  .|  .
GLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQ

DFD--------CKELQNVDLNTKDLLKKLLKVNPSERITPEQALQHPYF
  .        | .         .. |.  . .|..| | ..   | .|
PPNDYPMSFVCCPD------EMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 14827.AA ULK 256-312 29 2.7e-07 22.02 In-house 26-96 (324) Show / Hide 
Range on Protein: 256-312
Range on HMM: 26-96/324
Sequence Identity: 29% (21 aa)

T-NKHFAIKAFLKEKLIEEEKGYE------SFYNEIMLMRCIK---NKN--ALKLIDIWESK--NSYYLIM
| |...|.|   | |... .. .|      .. ||| .|. .|   ..|    ||.|. |..  | .|.||
TQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIM
Kinase 14827.AA Ciliate-E2a 204-218 60 4.4e-07 16.92 In-house 1-15 (275) Show / Hide 
Range on Protein: 204-218
Range on HMM: 1-15/275
Sequence Identity: 60% (9 aa)

YKAVRKLGKGSFASV
||...|.|||.|.||
YKFIKKIGKGNFGSV
Kinase 14827.AA ULK 256-312 27 7.6e-07 20.02 In-house 27-99 (329) Show / Hide 
Range on Protein: 256-312
Range on HMM: 27-99/329
Sequence Identity: 27% (20 aa)

TNKHFAIKAFLKEKLIEEEKGYE------SFYNEIMLMRCIK--------NKNALKLIDIWESK--NSYYLIM
.|. .|.|  .|.|...... .|      .. ||| .|. .|        ..|  ||.|. |..  | .|.||
VNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIM
Kinase 14827.AA CDPK 260-325 27 4e-06 15.09 In-house 29-95 (271) Show / Hide 
Range on Protein: 260-325
Range on HMM: 29-95/271
Sequence Identity: 27% (19 aa)

FAIKAFLKEKLIEEEKGYESFYNEIMLMRCIKNKNALKLIDIWESKNSYYLIMP--VCYGGSLLDRIA
.|.|   | .....|.  ..| |||.... .   | .|.    . .. ||..|   .|.|| |.|.|.
VAMKIIPKSRVKDKEQ-QQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYII
Kinase 14827.AA Ciliate-E2 204-218 53 0.000172 11.31 In-house 1-15 (365) Show / Hide 
Range on Protein: 204-218
Range on HMM: 1-15/365
Sequence Identity: 53% (8 aa)

YKAVRKLGKGSFASV
|| ..|.|.|.|.||
YKFIKKIGQGNFGSV
Kinase 14827.AA APH 356-402 22 0.000259 15.59 Pfam 161-207 (248) Show / Hide 
Range on Protein: 356-402
Range on HMM: 161-207/248
Sequence Identity: 22% (11 aa)

QMLEALLNLKQQGILHRDLKPDNILLCSPNQVEPM--IIDFGLATFQDV
..|||..   . ...|.|..|.|...  . . ...  .||.. |.. |.
AWLEAHWP--PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGDP
Kinase 14827.AA RSK 247-324 23 0.001526 9.25 In-house 11-92 (278) Show / Hide 
Range on Protein: 247-324
Range on HMM: 11-92/278
Sequence Identity: 23% (19 aa)

KVYLVNLV---GTNKHFAIKAFLKEKLIEEEKGYESFYNEIMLMRCIK-NKNALKLIDIWESKNSYYLIMPVCYGGSLLDRI
||.|.  .    |....| |   | |..  .|  .    |.  .  ..  ..  .| .  . .   ||||  | || |....
KVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHL
Kinase 14827.AA Ciliate-E2-Unclassified 204-218 40 0.002235 7.6 In-house 1-15 (352) Show / Hide 
Range on Protein: 204-218
Range on HMM: 1-15/352
Sequence Identity: 40% (6 aa)

YKAVRKLGKGSFASV
|| ....|.|.|..|
YKIIKQIGQGGFGKV
Kinase 14827.AA CAMK-Unique 256-325 17 0.003109 6.3 In-house 23-127 (363) Show / Hide 
Range on Protein: 256-325
Range on HMM: 23-127/363
Sequence Identity: 17% (19 aa)

TNKHFAIKAFLKEKLIEEEKGYE-----------------SFYNEIMLMRCIKNKNALKLIDI----WESKN---------------SYYLIMPVCYGGS
| | .|.| . |..  ...|...                 .. .|. ...  .  | .|| |.     . ..                .|..|  | || 
TGKKWACKMVKKQT-HGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGD

LLDRIA
|.| |.
LFDWIQ
Kinase 14827.AA ULK 204-218 50 0.023948 4.21 In-house 1-16 (324) Show / Hide 
Range on Protein: 204-218
Range on HMM: 1-16/324
Sequence Identity: 50% (8 aa)

YKAVRKLGKGSFA-SV
|   ..||||||.  |
YCLNHCLGKGSFGVKV
Kinase 14827.AA ULK 204-218 53 0.024344 4.08 In-house 1-15 (329) Show / Hide 
Range on Protein: 204-218
Range on HMM: 1-15/329
Sequence Identity: 53% (8 aa)

YKAVRKLGKGSFASV
|   ..||||||. |
YCLNHCLGKGSFGKV
Kinase 14827.AA CAMK1 204-218 33 0.028416 2.34 In-house 1-15 (276) Show / Hide 
Range on Protein: 204-218
Range on HMM: 1-15/276
Sequence Identity: 33% (5 aa)

YKAVRKLGKGSFASV
|.   ..|.|.|. |
YEFGKEIGRGAFSEV
Kinase 14827.AA CDPK 204-218 53 0.030547 2.92 In-house 1-15 (271) Show / Hide 
Range on Protein: 204-218
Range on HMM: 1-15/271
Sequence Identity: 53% (8 aa)

YKAVRKLGKGSFASV
||  ..||||.| .|
YKIKKVLGKGHFGQV
Kinase 14827.AA Pkinase 204-218 53 0.195074 6.16 Pfam 1-15 (293) Show / Hide 
Range on Protein: 204-218
Range on HMM: 1-15/293
Sequence Identity: 53% (8 aa)

YKAVRKLGKGSFASV
|. .||.|.|||..|
YHIGRKIGSGSFGCV