Gene 2256 (Tetrahymena)

2256

Species: Tetrahymena
Alias: 57.m00195, 3709.m00055, PreTt02256, TTHERM_00474550, 2256, 426
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2a

Sequence

Name Sequence Type Origin Length Description Download
2256.AA Protein None 761 None Fasta, JSON
2256.kin_dom Protein Kinase Domain None 278 None Fasta, JSON
2256.NA RNA None 2286 None Fasta, JSON

Protein domain

Protein domains of 2256.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 2256.AA Ciliate-E2a 135-412 40 4.90000000001e-164 486.72 In-house 1-275 (275) Show / Hide 
Range on Protein: 135-412
Range on HMM: 1-275/275
Sequence Identity: 40% (115 aa)

FEIQKKIGKGKYAKVYKVRRKDNNQLYAVKYLHKMKLATIEDAQAALFNELKILRMIDHPNCIKLIATYEDNNGYYILTELLDSEKSLQGELTKFQNPQF
....||||||....||....|.... .|.|...| |.. ... .....||..|.|..||||.|||. .|||.| ||. .|.... ..|  .. . .. ..
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEG-GELYDKIKQCKRFFE

GYQVVRHILKQLI-KGIEYVHSLGIMHRDLKPQNIMFA-NSDSS-SLSNLKIIDFGLAQFI--NDPNYIYVHVGTPGYVAPEILANESE-KHR-YTEKCD
 .|....|..||. .|..|.|...||||||||.||.|  .| .|  .|..||||||||.||  ....|.....|||||||||.|.|. . ||. |..|||
EIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCD

LFSIGVVFHILQVISNKKKILTGRSVFPGKKFSQVLQSNKECKIDLRGPK-YDELNKDAIDLLGKLLEPNPLKRPSATDALLHKFF
..|.||.|.||         |.|...|.||.....||.||.||||. .|  . .. |...||. |.||..| ||..|..|| |..|
MWSCGVIFYIL---------LCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 2256.AA Ciliate-E2 135-412 22 5.3e-85 288.69 In-house 1-365 (365) Show / Hide 
Range on Protein: 135-412
Range on HMM: 1-365/365
Sequence Identity: 22% (89 aa)

FEIQKKIGKGKYAKVYKVRR-----------------------KDNNQLYAVKYLHKMKLATIEDAQAALF---------NELKILRMIDHPNCIKLIAT
....||||.| ...|||...                       |.....||.|...| ..  |.  .  .          ||..||. ..||| ||.. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YE--DNNGYYILTELLDSEKSLQ----------------GELTKFQNPQFGYQVVR-------HILKQLIKGIEYVHSLG-IMHRDLKPQNIMFANSDSS
..  |.| .|. .|...    ..                . .| ..  .. .|...       ... ..|...|| || . |.|||.||.||.|      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

SLSNLKIIDFGLAQFINDP-----------NYIYVH----------------------VGTPGYVAPEILANES-----EKHRYTEKCDLFSIGVVFHIL
    .|||||||.....|.           .|.. .                      .|||||.||||| ...     ....|..|||..|.||.....
----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

QVISNKKKILTGRSVFPGKKFSQVLQSNKECKIDLRGP--------------KYDELNKDAIDLLGK----LLEPNPLKRPS-ATDALLHKFF
         |.|.  |        .| .|.||||.. |              ..... ....||. |    .|. .| ||.. . ..| |..|
---------LFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 2256.AA CAMK 140-412 19 1.7e-75 242.55 In-house 1-425 (425) Show / Hide 
Range on Protein: 140-412
Range on HMM: 1-425/425
Sequence Identity: 19% (85 aa)

KIGKGKYAKVYKVRRKDNN------------QLYAVKYLHKMKLAT------------------------IEDAQAALFNELKILRM-------IDHPNC
..|.| ..||.....| ..            | .|.| . | ||                           .  .. ...|..|...       .|||| 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLIATYEDNNG-------------------YYILT---ELLDS-EK--SLQGELTKFQN-------------PQFGYQVVRHILKQLIKGIEYVHSLGI
|||. .|||..                    .|. .   |. .  |    |   ...  .               |  . .|.. .|.. ...| ||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

MHRDLKPQNIMFANSDSSSL------------SNLKIIDFGLAQFINDPN------------------------YIYVHVGTPGYVA-PEILAN------
.|||||| ||.. .....|              |.||||||.|..... .                          .  .|||.|.| ||.|        
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----ESEKHRYTEKCDLFSIGVVFHILQVISNKKKILTGRSVFPGK-------------KFSQVLQSNKECKIDLRGPKYDELN----------------
      ||  |..|||  |.||.  |.         |.|.. | |.               .. ..  ...| |   |. ...                 
QNATDEEKPYYGPKCDMWSCGVILYIM---------LCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFH

----KDAIDLLGKLLEPNPLKRPSATDALLHKFF
    ....||. |.|...| ||......| |...
HFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 2256.AA S_TKc 135-412 28 1.4e-73 251.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 135-412
Range on HMM: 1-231/231
Sequence Identity: 28% (84 aa)

FEIQKKIGKGKYAKVYKVRRKDNNQLYAVKYLHKMKLATIEDAQAALFNELKILRMIDHPNCIKLIATYEDNNGYYILTELLDSE-KSLQGELTKFQNPQ
.|| .||||| ..||||.| |. ....|.| ..             . .|..||.. .||| .||. ...| . .|. .|..|    .|   . | . . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FGYQVVRHILKQLIKGIEYVHSLGIMHRDLKPQNIMFANSDSSSLSNLKIIDFGLAQFINDPNYIYVHVGTPGYVAPEILANESEKHRYTE-KCDL
    |   ..|....|.....|| ||.||.||||||.||.. .       ..||.||||| ..      .  .||| |.|||.|        |.  ||| 
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL-------GYGKCKCDW

FSIGVVFHILQVISNKKKILTGRSVFPGKKFSQVLQSNKECKIDLRGPKYDELNKDAIDLLGKLLEPNPLKRPSATDALL-------HKFF
 |.|... ..         |.|.  ||     ....  .               ..|.|.. |.|. .| |||.| .||        | .|
WSCGCILYEM---------LCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 2256.AA AGC 135-412 21 3.6e-66 169.11 In-house 1-395 (395) Show / Hide 
Range on Protein: 135-412
Range on HMM: 1-395/395
Sequence Identity: 21% (89 aa)

FEIQKKIGKGKYAKVYKVRRK------DNNQLYAVKYLH------KMKLATIEDAQAA--------LFNELKILRMID----------HPNCIK-LIATY
||. | |||| . ||| ||.|      |....||.| |       ..|  ..| ....        ...| .|| ...          ||. .| |  ..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDNNG--YYILTEL-------------LDSEKSLQGELTKFQNPQFGYQVVRHILKQ-------LIKGIEYVHS-LGIMHRD-LKPQNIMFANSDSSSLS
.|..    |.. |.             ...  .||| .   ..  |  ...|... .       .. ..|| || .|| ||| ||| ||.. .       
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRR---KEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED-----G

NLKIIDFGLA-QFINDP--------------------------------------------------NYIYVHVG--TPGYVAPEILANESEKHRYTEKC
..|. ||||. ...||.                                                  .  .  .|  || |.|||||        |.  |
HIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL--------YGKAC

DLFS--IGVVFHILQVISNKKKILTGRSVFPG--------------KKFSQVLQSNKECKIDLRGPKY--------DELNKDAIDLLGKLLEPNPLKRPS
|  |   |...  .         |||.. | |              ..| ...  . . . ... | .        ... ..| ||. |||...| ||. 
DWWSFGLGCLMYEM---------LTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLG

----------ATDALLHKFF
          | .   |..|
CGGNDFGDKGAEEIKNHPWF
Kinase 2256.AA Pkinase 135-412 25 3.9e-65 227.49 Pfam 1-293 (293) Show / Hide 
Range on Protein: 135-412
Range on HMM: 1-293/293
Sequence Identity: 25% (78 aa)

FEIQKKIGKGKYAKVYKVRRKDNNQLYAVKYLHKMKLATIEDAQAALFNELKILRMIDHPNCIKLIATYEDNNGYYILTELLDS-EKSLQGELTKFQ---
..| .|||.| ...||| ..|......||| . | .    .| .... .|..|.....||| ..|. ..||.. .|. .|...  .. ..   .  .   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

NPQF--GYQVVRHILKQLIKGIEYVHSLGIMHRDLKPQNIMFANSDSSSLSNLKIIDFGLAQFI-NDPNYIYVHVGTPGYVAPEILANESEKHRYTEKCD
.  |   .........|...|.|| || ||.||||||.||..  ..    . .||.||||| .. . .|  .. .|||.|.|||..    .   |. |.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIR---GGQYYGPKVD

LFSIGVVFHILQVISNKKKILTGRSVFPGK------KFSQVLQSNKECKIDLRGPKYDELN-----------------KDAIDLLGKLLEPNPLKRPSAT
 .|.|......           ||  |||.         |... .......   |. ..                   ....|.. ..|...| |||.|.
MWSCGCILYEMLC---------GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

DALLHKFF
..| |..|
QILQHPWF
Kinase 2256.AA CAMK1 240-412 34 1.1e-55 160.32 In-house 111-276 (276) Show / Hide 
Range on Protein: 240-412
Range on HMM: 111-276/276
Sequence Identity: 34% (61 aa)

RHILKQLIKGIEYVHSLGIMHRDLKPQNIMFANSDSSSLSNLK--IIDFGLAQFINDPN-YIYVHVGTPGYVAPEILANESEKHRYTEKCDLFSIGVVFH
||| ||... .|| ||.||.||||||.|. ... |  |   .|  |.||||...... . . .  .|||||||||.|.. .    |  .||..||||.. 
RHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSK--IKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK-DKPYDKACDMWSIGVITY

ILQVISNKKKILTGRSVFPGKK-FSQVLQSNKECKIDLRGPKYDE-LNKDAIDLLGKLLEPNPLKRPSATDALLHKFF
||         |.| . | ..   .. .. .|.|...   |  |.  .. | |.. ..||..| ||......| |...
IL---------LCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 2256.AA Ciliate-E2-Unclassified 135-412 23 3e-53 183.07 In-house 1-352 (352) Show / Hide 
Range on Protein: 135-412
Range on HMM: 1-352/352
Sequence Identity: 23% (85 aa)

FEIQKKIGKGKYAKVYKVRRKDNNQLYAVKYLHKMKLATIEDAQA---------ALFN-----------ELK-ILRMIDHPNCIKLIATYEDNNGYYILT
..|.|.||.| ..||||...|...|.|| ||..|..       .          ...|           ... ||....||. .|.. . .| .  || .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

ELLDSEKSLQGELTKFQN-------------------PQFGYQVVR-----HILKQLIKGIEYVHSLG-IMHRDLKPQNIMFANSDSSSLSNLKIIDFGL
|...     .|.| .. .                    .|  | ..     ....|...|.|| |. . | |||.||.||.| |. .    ..||||||.
EYCE-----GGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--NYYIKIIDFGI

AQFINDPNYIYVH-----------------VGTPGYV----APEILANESEKHRYTEKCDLFSIGVVFHILQVISNKKKILTGRSVFPGKKFSQ------
. .....|... .                 .|||.|     |||.| ..   |.  .||| .| ||... .         |.|.  |....  |      
SKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEM---------LFGYYPFYDNNCEQHQQLIT

----------VLQSNKECKIDLRGPKY----DELNKDAIDLLG----KLLEPNPLKRPSATDALLHKFF
          ..|  |...|. .  .     . ... |.|..     |.|. || ||... ..| | .|
QWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 2256.AA CAMKL 135-314 25 1e-45 143.75 In-house 1-206 (297) Show / Hide 
Range on Protein: 135-314
Range on HMM: 1-206/297
Sequence Identity: 25% (53 aa)

FEIQKKIGKGKYAKVYKVRR-KDNNQLYAVKYLHKMKLATIEDAQAA-----------LFNELKILRMID---HPNCIKLIATYEDNNG------YYILT
..| | .||| ..||   .  . ... .|.| ..| |.  .. ...            .. | .|..|..   ||| |||  ..|. .       .|. .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELLDSEK-SLQGELTKFQNPQ--FGYQVVRHILKQLIKGIEYVHSLGIMHRDLKPQNIMFANSDSSSLSNLKIIDFGLAQFIND-----PNYIYVHVGTP
|. ..    |.  . |  ..   .     |.. .|.. ...| ||.|| |||.|| ||.. .....   |.||||||.. .. .      .    . |.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

GYVAPEILA
 | ||||..
PYMAPEIFQ
Kinase 2256.AA CMGC 135-335 20 1.4e-43 140.49 In-house 1-325 (513) Show / Hide 
Range on Protein: 135-335
Range on HMM: 1-325/513
Sequence Identity: 20% (68 aa)

FEIQKKIGKGKYAKVYKVRR--------------KDNNQLYAVKYLHKMKLATIEDAQAA-----------LFNELKILRMI-----------------D
.|| ||||.| |..||| |               ...|...|.|   |.|..  .. ||             . |.|||...                 .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIK---KIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKH

HPNCIKLIATYEDNN-----------------GYYILTELLDSEKSLQGELTKFQNP-------QFGYQV------------VRHIL------KQLIKGI
|.|..||.  . ..|                   |. .|..  ...| . . . |..        .   .            .....      .|...|.
HNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYM--DHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGL

E--YVHSLG--IMHRDLKPQNIMFANSDSS---------------SLSNLKIIDFGLAQFINDP----------------------NYIYVHVGTPGYVA
.  | || .  |.||||||.||.. .   .               .  .|||.||||| .....                        ..  | |  | |
KLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRA

PEILANESEK------HRYTEKCDLFSIGVVF
|||| . ..       . ||...|  |.| .|
PEILLGWKHYTNHNYSMHYTTPIDMWSVGCIF
Kinase 2256.AA STE 135-332 22 2.6e-41 143.56 In-house 1-255 (359) Show / Hide 
Range on Protein: 135-332
Range on HMM: 1-255/359
Sequence Identity: 22% (59 aa)

FEIQKKIGKGKYAKVYKVRRK------DNNQL---------YAVKYLHKMK------------LATI-EDAQAALFNELKILRMID--HPNCIKLIATYE
.|...||||| . .||| ...      .....         .|.| ... .            | .. .. .  . .|.||..  .  ||| .| . .|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DN-------NGYYILTELLDSEKSLQGELTKFQNPQFG------------YQVVRHILKQLIKG-IEYVHSLGIMHRDLKPQNIMFANSDSSSLSNLKII
..       .  .|  |..|   ||   . .   ....             .....|..|..||  .| ||..|.|||.||.||..           |..
KEGHNHKNDDELWICMEYMD-GGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLC

DFGLAQFINDPNY-----------------IYVHVGTPGYVAPEILANESEKHR---YTEKCDLFSIG
|||..  ..| .                   .  |||| . |||.. ..... |   |..|||  |.|
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLG
Kinase 2256.AA CDPK 240-412 35 7.2e-40 120.11 In-house 106-271 (271) Show / Hide 
Range on Protein: 240-412
Range on HMM: 106-271/271
Sequence Identity: 35% (63 aa)

RHILKQLIKGIEYVHSLGIMHRDLKPQNIMFANSDSSS--LSNLKIIDFGLAQFINDP-----NYIYVHVGTPGYVAPEILANESEKHRYTEKCDLFSIG
. | .|..  . | || .|.||||||.||.| . ...|    |.|.||.|..   .       ....  .||| |.|||.|     ...| ||||. |.|
AYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVL-----QKKYNEKCDIWSCG

VVFHILQVISNKKKILTGRSVFPGKKFSQVLQSNKECKIDLRGPKYDELNKDAIDLLGKLLEPNPLKRPSATDALLHKFF
|.  ||         | |.  | ||  ...... |..| .. ||  |.  ..|.||  |.|...| || || .|| |. |
VILYIL---------LCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 2256.AA CAMK1 135-216 34 1.2e-29 83.32 In-house 1-90 (276) Show / Hide 
Range on Protein: 135-216
Range on HMM: 1-90/276
Sequence Identity: 34% (31 aa)

FEIQKKIGKGKYAKVYKVRRKDN---NQLYAVKYLH-KMKLATIE--DAQAALFNELKILR---MIDHPNCIKLIATYEDNNGYYILTELL
.|..|.||.|  ..||.. .|..   .. ||.|..  |  ... .    |.|| ||. |..    |||||.||..  ||..| .|. .||.
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELV
Kinase 2256.AA CDPK 135-216 38 6.4e-21 61.09 In-house 1-85 (271) Show / Hide 
Range on Protein: 135-216
Range on HMM: 1-85/271
Sequence Identity: 38% (33 aa)

FEIQKKIGKGKYAKVYKVRRK-DNNQLY-AVKYLHKMKLATIEDAQAALFNELKILRMIDHPNCIKLIATYEDNNGYYILTE--LL
. | |..||| .  |.||  |  .||   |.|   | ..   |. |  .|||..||. .|||| ||.  .|.|.. ||| .|  ..
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQ-QQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYC
Kinase 2256.AA TyrKc 135-412 20 1.9e-13 -5.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 135-412
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)

FEIQKKIGKGKYAKVYKVRRKDNNQLYAVKYLHKMKLATIEDAQAALFNELKILRMI--DHPNCIKLIATYEDN-------NGYYILTELLDSEKSLQGE
 .  ||.| | . .||| . |   .  ||| |.. .       .... .|..|....  .||| ..|..   .          ..|..|. .   .|.  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDY

LTKFQNPQFGYQVVRHILKQLIKGIEYVHSLGIMHRDLKPQNIMFANSDSSSLSNLKIIDFGLAQFINDP-------NYIYVHV--GTPG-----YVAPE
| | ..  .  .   ..  |  .| || || .. ||||   |.. ..         || ||||. .| |         |. .    |. .       |||
LRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

ILANESEKHRYTEKCDLFSIGVV----FHILQVISNKKKILTGRSVFPG-----KKFSQVLQSNKECKIDLRGPK-YDE-----LNKDAIDLLGKLLEPN
 .     ....|.| | .| ||.    |              | .  ||     .. ..|..  |. .   . |  | .       ..  ..  .  . .
CI----NYGKFTTKSDVWSFGVCMWEIFT------------YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHED

PLKRPSATDALLHKFF
| .||. ..   |..|
PEDRPTFSEI--HECF
Kinase 2256.AA CMGC 351-412 26 2.4e-12 35.93 In-house 441-513 (513) Show / Hide 
Range on Protein: 351-412
Range on HMM: 441-513/513
Sequence Identity: 26% (21 aa)

RSVFPGKKFSQVLQSNKECKIDLRGPKYDE----------------LNKDAIDLLGKLLEPNPLKRPSATDALLHKFF
...||.... .  . ||   .. .  .| |                ....||||| |.|. .| ||..| .|| | .|
KNLFPWHPNWDD-N-NKKAMVF-NW-IY-EEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 2256.AA CAMKL 376-412 32 4.2e-09 25.05 In-house 262-297 (297) Show / Hide 
Range on Protein: 376-412
Range on HMM: 262-297/297
Sequence Identity: 32% (12 aa)

PKYDELNKDAIDLLGKLLEPNPLKRPSATDALLHKFF
|.. ..  |..||. |.|..|| |||.. . . |...
PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 2256.AA Pkinase_Tyr 135-215 25 2.1e-08 29.09 Pfam 1-88 (270) Show / Hide 
Range on Protein: 135-215
Range on HMM: 1-88/270
Sequence Identity: 25% (23 aa)

FEIQKKIGKGKYAKVYKVRRK----DNNQLYAVKYLHKMKLATIEDA--QAALFNELKILRMI-DHPNCIKLIATYE-DNNG--YYILTEL
 .. ||.|.| . .||| . |    ....  ||| | |    . ...  ......|.||.. . .||| ..|..    .     .|| .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEY
Kinase 2256.AA STE 383-412 34 3e-06 18.35 In-house 328-359 (359) Show / Hide 
Range on Protein: 383-412
Range on HMM: 328-359/359
Sequence Identity: 34% (11 aa)

KDAIDLLGKLLEPNPLKRPSATDALL--HKFF
.. .| . | |. .| |||.|.. |   |.|.
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI