Gene 23956 (Tetrahymena)

23956

Species: Tetrahymena
Alias: 1, 99.m00197, PreTt23956, 23956, TTHERM_00668030
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2a

Sequence

Name Sequence Type Origin Length Description Download
23956.AA Protein None 508 None Fasta, JSON
23956.kin_dom Protein Kinase Domain None 248 None Fasta, JSON
23956.NA RNA None 1527 None Fasta, JSON

Protein domain

Protein domains of 23956.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 23956.AA Ciliate-E2a 83-330 38 6.1e-135 399.63 In-house 13-275 (275) Show / Hide 
Range on Protein: 83-330
Range on HMM: 13-275/275
Sequence Identity: 38% (101 aa)

GHVKKVVKKDTKEERVMKIVNKKYVDNSVNNFNITNEIIYLSQLSHPNIIKAYEYYKDSINYYFIFEFVDSGSLIDRIIECD-FFSE-KLVKTVAKQVL-
|.|... .|.|.....||...||. ..  ......||| ...||.|||||| ||.|.|  |||...|....|.|.|.|..|. ||.| . .. . .| | 
GSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLW

EVLAYIHNRHIVHRDITLKNILMN--SFSKQQDLQIKIIDWGNATNIQGNEN--LKQITGELHFRA------PEVLSQ-SYSYGCDIWSLGVVIYTLIEG
. |.|.|.|.|.|||. . |||..  |....|...|||||.| ||.|...|.  ..|. |  .. |      .|||.. .|.. ||.||.||..|.|. |
QGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCG

EVPFVKKTEAEIIQSIKNESLSFSSSN-WENVTIECKQIVQSMLQKDHKKRPKAVELLENKWF
. ||  ||..||.|..|.  ..|.... ||... |||.... ||.||.|||..| ..|...||
KPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 23956.AA CDPK 83-330 38 8.1e-84 256.97 In-house 13-271 (271) Show / Hide 
Range on Protein: 83-330
Range on HMM: 13-271/271
Sequence Identity: 38% (101 aa)

GHVKKVVKK-DTKEER-VMKIVNKKYVDNSVNNFNITNEIIYLSQLSHPNIIKAYEYYKDSINYYFIFE--FVDSGSLIDRIIECDFFSEKLVKTVAKQV
| |.||..|  |..||  |||..|. | ..    .  |||  |.|| |||||| ||.| |. |||...|  ..  | |.|.|||   |.||    . .|.
GQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHFTEKEAAYIMRQI

LEVLAYIHNRHIVHRDITLKNILMNSFSKQQ--DLQIKIIDWGNATNIQGN-----ENLKQITGELHFRAPEVLSQSYSYGCDIWSLGVVIYTLIEGEVP
|  ..|.|.. |||||..  ||| .| .. .    .||.|||| ... ..|     . ..|. |  .  ||||| ..| . |||||.||. |.|. |. |
LSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDIWSCGVILYILLCGYPP

FVKKTEAEIIQSIKNESLSFSSSNWENVTIECKQIVQSMLQKDHKKRPKAVELLENKWF
|  |.. ||....|.   ||   .|.... |.|. .. ||..| ||| .| . |. .||
FYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 23956.AA CAMK 83-330 20 1.7e-76 245.8 In-house 8-425 (425) Show / Hide 
Range on Protein: 83-330
Range on HMM: 8-425/425
Sequence Identity: 20% (85 aa)

GHVKKVVKKDTK------------EERVMKIVNKKYVDN-------------------------SVNNFNITNEIIYLSQLS-------HPNIIKAYEYY
| ||... | |.            ..  .||..|| ...                          ..  |. .||  ...|.       |||||| ||.|
GKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVY

KD-------------------SINYYFIF---EFVDSG----SLIDRIIEC---------------DFFSEKLVKTVAKQVLEVLAYIHNRHIVHRDITL
 |                     ..|...   |... |     | |.|.|                  |.|. .... .|... ..|.|...|||||. .
EDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKP

KNILMNSFSKQQD------------LQIKIIDWGNATNIQG------------------------NENLKQITGELHFRA-PEVLSQS------------
 |||... .. .|             .|||||.| |. ...                        .. .|   | ... | ||||...            
ENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEE

---YSYGCDIWSLGVVIYTLIEGEVPFVKKTEAEIIQ-------------SIKNESLSFSSSN------------WENVTIE--------CKQIVQSMLQ
   |.. ||.||.||. |..  |. ||  ... ||..              |..   .| ..             | ... |        ||. ...|||
KPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQ

KDHKKRPKAVELLENKWF
.| .||... . |. .|.
VDPEKRMTIEQCLNHPWM
Kinase 23956.AA Ciliate-E2 79-330 25 1.5e-68 234.06 In-house 14-365 (365) Show / Hide 
Range on Protein: 79-330
Range on HMM: 14-365/365
Sequence Identity: 25% (93 aa)

KFKKGHVKKVVK------------------KDTKEERVMKIVNKKYVDNSVNNFNIT----------NEIIYLSQLSHPNIIKAYEYYK--DSINYYFIF
. .|. |.|| |                  |... .  |||..|. . .  .  .|           ||   |.||.|||||| ||...  |  |.|...
SVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVM

EFVDSGSLIDRIIECDFFS-----------EKLVKTVAKQVLE---------------VLAYIHNRH-IVHRDITLKNILMNSFSKQQDLQIKIIDWGNA
|... |.| |.|.... ..           || .|.. ||.|.                | |.|... |.|||| . |||.          |||||.|..
EYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----------IKIIDFGLS

TNIQGN--------------------------------ENLKQITGELHFRAPEVLS-QS---------YSYGCDIWSLGVVIYTLIEGEVPFVKKTEAE
.... .                                .  ..| | ... |||.|. ..         |.| ||||||||..| .. |. ||       
KKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-------

IIQSIKNESLSFSSS--------------NWENVTIECKQIVQS----MLQKDHKKRPK-AVELLENKWF
 .| ||.  ..|..               .|.... |||.. .     ||||| .||.  . ..|...||
-QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
S_TKc 23956.AA S_TKc 78-330 27 7.9e-66 225.92 SMART 1-231 (231) Show / Hide 
Range on Protein: 78-330
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

MKFKK-------GHVKKVVKKDTKEERVMKIVNKKYVDNSVNNFNITNEIIYLSQLSHPNIIKAYEYYKDSINYYFIFEFVDS--GSLIDRIIECDF---
 .. .       | |.|...|.|...  .||..           .| .||  |..  ||||.| |... |  ..|...|..|   |.| |.| ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEKLVKTVAKQVLEVLAYIHNRHIVHRDITLKNILMNSFSKQQDLQIKIIDWGNATNIQGNENLKQITGELHFRAPEVLSQSYSY-GCDIWSLGVV
   |.|  .. ...|... |.|.|...|.|||.   |||...       .|||.| | |. .      . . | ....|||||  .|..  ||.||.|..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCI

IYTLIEGEVPFVKKTEAEIIQSIKNESLSFSSSNWENVTIECKQIVQSMLQKDHKKRPKAVELLE-------NKWF
.| .. |. ||   ....... |.              . |.|.... .|||| .||| | |.|.         ||
LYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 23956.AA Pkinase 83-330 27 2.1e-60 211.8 Pfam 13-293 (293) Show / Hide 
Range on Protein: 83-330
Range on HMM: 13-293/293
Sequence Identity: 27% (80 aa)

GHVKKVVKKDTKEERVMKIVNKKYVDNSVN--NFNITNEIIYLSQLSHPNIIKAYEYYKDSINYYFIFEFVDSG----SLIDRII--ECDFF--SEKLVK
| |.| ..|.| .. ..||..|.  . ...  .... .|| ..  |.||||.. |... |. ..|...|... |    .| |.|   .   |  ||. .|
GCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECK

TVAKQVLEVLAYIHNRHIVHRDITLKNILMNSFSKQQDLQI----KIIDWGNATN--IQGNENLKQITGELHFRAPEVLS--QSYSYGCDIWSLGVVIYT
 ...|.|. |.|.|.. |.|||. . |||...     . .|    ||.|.| |    .  |. .. ..| ....||||.   | |.. .|.||.|...| 
FYMYQILRGLEYCHSMGIIHRDLKPENILIDN-----NGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYE

LIEGEVPFVKK------TEAEIIQSIKNESLSFSSSNWENVT-----------------IECKQIVQSMLQKDHKKRPKAVELLENKWF
.. |. ||  .      .. ..|. |.   |.|....| ..                   |||... ..|.|| |||| | ..|. .||
MLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 23956.AA CAMK-Unique 83-330 22 6.3e-60 196.43 In-house 13-363 (363) Show / Hide 
Range on Protein: 83-330
Range on HMM: 13-363/363
Sequence Identity: 22% (80 aa)

GHVKKVVKKDTKEERVMKIVNKKYVDNSVNNFN-----------------ITNEIIYLSQLSHPNIIKAYEY----YKDSI---------------NYYF
|||...  . |. ....|.|.|... |...  .                  ..|.  .  ..|||||| |..    . |.                ..| 
GHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYI

IFEFVDSGSLIDRIIE--------------------CDFFSE--KLVKTVAKQVLEVLAYIHNRHIVHRDITLKNILMNSFSKQ-----------QDLQI
. |... | | | |..                       |||   .. ..  ..|...|| |.  |||||. | ||. ..  |             .. |
VMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHI

KIIDWGNATNIQGNENLK---QITGELHFRAP--------------EVLS-QSYSYGC----DIWSLGVVIYTLIEGEVPFVKKTEA--------EIIQS
|..|.| .. ...|.       . | . . ||              ||.  | |.. |    |||||||. |....|. ||   .|.        ||...
KLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFEC

IKNESL-SFSSSNWEN---VTIECKQIVQSMLQKDHKKRPKAVELLENKWF
|.   . .|... |.    .. | |..|.  .. | ..| .| ||||. |.
ICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 23956.AA Ciliate-E2-Unclassified 83-330 23 5.9e-58 198.85 In-house 13-352 (352) Show / Hide 
Range on Protein: 83-330
Range on HMM: 13-352/352
Sequence Identity: 23% (81 aa)

GHVKKVVKKDTKEER-------VMKIVNKKYVDNS---------VNNFNITNEII--------YLSQLSHPNIIKAYEYYKDSINYYFIFEFVDSGSLID
| |.|...|..| .        ...|...|.. |.         .|| .  .            |... ||.|.| ... .|  | |.. |... |.|..
GKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQ

RIIECDF-----------------FSEKLVK-----TVAKQVLEVLAYIHNRH-IVHRDITLKNILMNSFSKQQDLQIKIIDWGNATNIQ----------
 | .. .                 |.|. .|     . ..|.|. | |.|  . |.||||.. |||...  |   ..|||||.|.. ..|          
YIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--NYYIKIIDFGISKKYQQNNNCDTNQQ

------GNENLKQITGELHFR----APEVLSQ-SYS----YGCDIWSLGVVIYTLIEGEVPFVKKTEAE----------------IIQSIKNESLSFSSS
       ........| . .     ||||| .  |.    | ||||||||..| .. |. ||  ... .                ..| ||.  ..|...
QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKF

NW----ENVTIECKQIVQ----SMLQKDHKKRPKAVELLENKWF
.|     ..  |.| ...    .||.|. .||. . ..|.  ||
PWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 23956.AA CAMKL 85-330 26 6e-53 167.24 In-house 15-297 (297) Show / Hide 
Range on Protein: 85-330
Range on HMM: 15-297/297
Sequence Identity: 26% (75 aa)

VKKVVK-KDTKEERVMKIVNKKYVD-NSVNNFN-----------ITNEIIYLSQLS---HPNIIKAYEYYKDSIN------YYFIFEFVDSGS--LIDRI
||  .  . |.|.  .||..||    . ... |           |. ||  ...|.   |||||| || . .. .      .| . | ...|.  | |.|
VKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYI

IECDF----FSEKLVKTVAKQVLEVLAYIHNRHIVHRDITLKNILMNSFSKQQDLQIKIIDWGNATNIQ-G----NENLKQITGELHFRAPEVLSQ---S
..       ..|.  .   .|... ..|.|...|||||| . |||  .  ..   .||||| | .. .. .    .. ||   | ... |||...    .
VKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKP

YS-YGCDIWSLGVVIYTLIEGEVPFVKKTEA----EIIQSIKNESLS-FSSSNWENVTIECKQIVQSMLQKDHKKRPKAVELLENKWF
|  .  ||||.||. |... |..||   | .    . |   ...  . .    |  |  .|... ..|||.. .|||.. .... .|.
YDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCGYYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 23956.AA RSK 85-330 25 1.4e-50 174.35 In-house 15-278 (278) Show / Hide 
Range on Protein: 85-330
Range on HMM: 15-278/278
Sequence Identity: 25% (67 aa)

VKKVVKKDTKEERVMKIVNKKYVDNSVNNFNITN-EIIYLSQLS-HPNIIKAYEYYKDSINYYFIFEFVDSGSLIDRIIECDF---FSEKLVKTVAKQVL
..|.. .||. .  ||...|. ....      |  |.  |.    ||.|.. .. ...    | | |..  | | ... .  .   |||. .. .. .. 
CRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIV

EVLAYIHNRHIVHRDITLKNILMNSFSKQQDLQIKIIDWGNATN--IQGNENLKQITGELHFRAPEVLS----QS-YSYGCDIWSLGVVIYTLIEGEVPF
  . ..| ..|.|||. . ||| .. |  ..  ||..| | .    .. |. ..   . ... |||.|     |. ..  ||.|||||..|..  | .||
LAVEHLHQQGIIHRDLKPENILYDDES--NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPF

VK---KTEAEIIQSIKNESLSFSSSNWENVTIECKQIVQSMLQKDHKKRPK-----AVELLENKWF
     .. .||.. |..  .|... ||.... |.| ... ||..| .||..     | |.....||
QGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 23956.AA STE 85-330 21 3.5e-43 149.8 In-house 16-359 (359) Show / Hide 
Range on Protein: 85-330
Range on HMM: 16-359/359
Sequence Identity: 21% (75 aa)

VKKVVKK-----DTKEE---------RVMKIVNKKYVDNSVNN------------FNIT---NEIIYLSQLS--HPNIIKAYEYYKDS-------INYYF
.|.. .|     .|.|.           .|..|..  .|.. .             ..    .||  .....  ||||.| | .| .         . . 
YKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWI

IFEFVDSGSLIDRII---ECDF-----------FSEKLVKTVAKQVLEV-LAYIHNRHIVHRDITLKNILMNSFSKQQDLQIKIIDWGNATNIQGN----
. |..| ||| | |    .| .           |.|........|.|.  |.|.|. ||.||||   |||.          .|..| | ..... .    
CMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCDFGVCGQLTDSMANI

-------------ENLKQITGELHFRAPEVLSQ-------SYSYGCDIWSLGVVIYTLIEGEVPFVKKTEA----EIIQSI--------------KNESL
             .. . ..|   . ||||..|        |.. ||||||| .|  ...|..|. . .      .|....              .  .|
QSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPL

SFSSSNW-------------ENVTIECKQIVQSMLQKDHKKRPKAVELLE--NKWF
    |.              .... |.|. ..  |||| .|||.| .||.   ...
PDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 23956.AA MSK 85-330 28 4.4e-43 143.48 In-house 15-277 (277) Show / Hide 
Range on Protein: 85-330
Range on HMM: 15-277/277
Sequence Identity: 28% (75 aa)

VKKVVKKDTKEERVMKIVN-KKYVDNSVNNFNITNEIIYLSQL-SHPNIIKAYEYYKDSINYYFIFEFVDSGSLIDRIIECDFFSEKLVKTVAKQVLEVL
..|.|..||  .  |||..    |       .   |.  |  . .|||| . .. ..|.   | . |..  | |  .|     |.|. .  .  ..   .
CRKCVHHDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAV

AYIHNRHIVHRDITLKNILMNSFSKQQD-LQIKIIDWGNATNIQGNENLKQIT--GELHFRAPEVLS-----QS-YSYGCDIWSLGVVIYTLIEGEVPFV
 ..| ..|.|||. . |||   |  ..|  ..|.|| | |     .|. .  .  . ||. |||.|      .. |.  ||.|||||. ||.  | ||| 
DHMHQKGIIHRDLKPENIL---FDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPFQ

------K---KTEAEIIQSIKNESLSFSSSNWENVTIECKQIVQSMLQKDHKKRPKAVELLENKWF
      .   .. .|| . |. .. || .  |.|.  . |  .| .|.|| |||... .|. . | 
QNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
TyrKc 23956.AA TyrKc 78-330 18 1.2e-10 -50.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 78-330
Range on HMM: 1-280/280
Sequence Identity: 18% (56 aa)

MKFKK-------GHVKKVVKKDTKEERVMKIVNKKYVDNSVNNFNITNEIIYLSQL--SHPNIIKAYEYYKDS-------INYYFIFEFVDSGSLIDRII
 ...|       | | | . |       ..   |.  ...     . .|.  ...|  .||||.. | .  ..         .. ..|... |.| |.. 
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ECD-FFSEKLVKTVAKQVLEVLAYIHNRHIVHRDITLKNILMNSFSKQQDLQIKIIDWGNATNIQGN-------ENLKQ---ITGE--LHFR--APEVLS
..   .. |     . |. .  .|.| ....|||.   |.| ..       ..|| | | . .|          .  ..     |   |  |  |||.. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

QS-YSYGCDIWSLGVVIY-TLIEGEVPFVK-----KTEAEIIQSIKNESLSFSSSNWE-----NVTIECKQIVQSMLQKDHKKRPKAVELLENKWF
 . ..   |.|| ||...  .  |. |        .. .|.|. .|.        | .       . |  || ..  . | ..||   |.   . |
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 23956.AA Pkinase_Tyr 118-215 21 3.9e-05 18.03 Pfam 52-152 (270) Show / Hide 
Range on Protein: 118-215
Range on HMM: 52-152/270
Sequence Identity: 21% (23 aa)

NEIIYLSQL-SHPNIIKAYEYYK-DSIN--YYFIFEFVDSGSLIDRIIEC----DFFSEKLVKTVAKQVLEVLAYIHNRHIVHRDITLKNILMNSFSKQQ
.|.  ..|| .||||.. |     ..    .| ..|..  |.| |   .     . .. |     . |. . ..| ......|||.  .|.| ..     
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----

DLQIKI
....||
NNVVKI
Efhand 23956.AA efhand 369-397 20 0.000474 19.24 Pfam 1-29 (29) Show / Hide 
Range on Protein: 369-397
Range on HMM: 1-29/29
Sequence Identity: 20% (6 aa)

SVAQLFQKLDTNHTGSLSKEEIAQVCKLQ
 . ..|...|... | ...||  ...| .
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 23956.AA EFh 369-397 20 0.003461 16.34 SMART 1-29 (29) Show / Hide 
Range on Protein: 369-397
Range on HMM: 1-29/29
Sequence Identity: 20% (6 aa)

SVAQLFQKLDTNHTGSLSKEEIAQVCKLQ
 . ..|...|... | ...||  ...|  
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
EFh 23956.AA EFh 406-434 24 1.4e-07 32.43 SMART 1-29 (29) Show / Hide 
Range on Protein: 406-434
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

QINDIFEELDIDKSGNISYNEFITIVSNK
.....|...| |..| |...||.......
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 23956.AA efhand 406-434 27 5.3e-07 30.05 Pfam 1-29 (29) Show / Hide 
Range on Protein: 406-434
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

QINDIFEELDIDKSGNISYNEFITIVSNK
.....|.|.| |..| |...||.......
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
Efhand 23956.AA efhand 442-465 37 3.8e-05 23.26 Pfam 1-24 (29) Show / Hide 
Range on Protein: 442-465
Range on HMM: 1-24/29
Sequence Identity: 37% (9 aa)

NVAKAFKYFDKDNSGFITQDELKR
 . ..|| ||||..|.|. .|...
ELKEMFKEFDKDGDGYIDFEEFCE
EFh 23956.AA EFh 442-470 31 0.003696 16.11 SMART 1-29 (29) Show / Hide 
Range on Protein: 442-470
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

NVAKAFKYFDKDNSGFITQDELKRSLGYS
 . ..|. ||||..|.|. .|.|. .   
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
EFh 23956.AA EFh 478-506 37 1e-06 29.02 SMART 1-29 (29) Show / Hide 
Range on Protein: 478-506
Range on HMM: 1-29/29
Sequence Identity: 37% (11 aa)

VWEEFMSKCDLNGDNKISFDEFKILVKGL
 ..| ... | .|| .|.|.||| ..| |
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 23956.AA efhand 478-506 34 3e-06 27.5 Pfam 1-29 (29) Show / Hide 
Range on Protein: 478-506
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

VWEEFMSKCDLNGDNKISFDEFKILVKGL
 ..|.... | .|| .|.|.||. ..| |
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL