28438

Species: Tetrahymena
Alias: 28438, 13.m00397, PreTt28438, TTHERM_00158480, 3829.m01253, 128
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2b

Sequence

Name Sequence Type Origin Length Description Download
28438.AA Protein None 596 None Fasta, JSON
28438.kin_dom Protein Kinase Domain None 254 None Fasta, JSON
28438.NA RNA None 1791 None Fasta, JSON

Protein domain

Protein domains of 28438.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 28438.AA Ciliate-E2b 15-269 34 8.60000000001e-159 485.95 In-house 1-272 (272) Show / Hide
Range on Protein: 15-269
Range on HMM: 1-272/272
Sequence Identity: 34% (95 aa)

VDESKLLGSGNCGSVYFGWKTDNTEQYLAIKQIPIN--SKFEITDSMLIEINLLRRLDHPNIVKFIDAKKTKDFMYLIMEFCNEGSIEDLIINQK---VS
....|.||.|..||||..|.|.||.||.|.|.|..|  ........||.|.|.|....||.|.|||...|....||..|||||.....|.|....   .|
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

ENEVLDYFKQICKAFRELNNKNILHGDVKPSNILLHN-SQCKLADFGVSKTIDKKSE----NTTMRGTPFFMAPQLLN-----NQPYTTKSDIWSLGITL
......|...||.....|.|.||...|.||.||.... ...||.|.|..|...||.|    ..|..|||..|||....     ...||.|.||||.||.|
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL

FFMLFKRLPWDEKVQKQHQLRQFITNEYDPDKFFSHCTNVIS--EFTLSLLKRMIVVDEEKRISWEELFKLV
........||.|.||......|.|...||...|.|.|.....  ...|..|..|..|......||...... 
YEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF

Kinase 28438.AA Ciliate-E2c 15-271 35 6.3e-93 315.03 In-house 1-310 (310) Show / Hide
Range on Protein: 15-271
Range on HMM: 1-310/310
Sequence Identity: 35% (109 aa)

VDESKLLGSGNCGSVYFGWKTD-------N---------TEQYLAIKQIPINSKFEITDSMLIEINLLRRLDHPNIVKFIDAKKTKDFMYLIMEFCNEGS
 |. . ||||. |.|| . .         |          .. |..| | ... ..|. |   |||... ..||.|.||.|||.|.   |||||.||.|.
IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT

IEDLIINQ-KVSENEVLDYFKQICKAFRELNNK-NILHGDVKPSNILLHNSQCKLADFGVSKTIDKKSEN-TT----MRGTPFFMAPQLLNN-QPYTTKS
 |..| .  | .| ..|.||.||  || .|  . ||.|.|.||.|||.|| . |.|||| || ..    . |.      |||..|||| |.  . ||.||
LEQYIYHKPKPNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGKNYYTEKS

DIWSLGITLFFMLFKRLPWD---------------EKVQK-QHQLRQFITN-------------EYDPDKFFSHCTNVISEFTLSLLKRMIVVDEEKRIS
||||||.||..||...|||.                  |  . .| | | .                . .|     . ||. .  |...|..|||||||.
DIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEEKRID

WEELFKLVIP
|.|.| . . 
WDEIFNHECI

Kinase 28438.AA ULK 15-267 32 1.2e-89 304.12 In-house 1-320 (324) Show / Hide
Range on Protein: 15-267
Range on HMM: 1-320/324
Sequence Identity: 32% (105 aa)

VDESKLLGSGNCG-SVYFGWKTDN--TEQYLAIKQIP----INSKFE-----ITDSMLIEINLLRRLD---HPN--IVKFIDAKKTKDF--MYLIMEFCN
   .. ||.|  |  || | . ..  . || |.|.|.    ...| |     . ..   ||.... |.   |||  |||..| ..|...   |.|||.||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

EGSIEDLIINQK----------VSENEVLDYFKQICKAFRELNNKNILHGDVKPSNILLHNSQ-------------CKLADFGVSKTIDKKSENTTMR--
 |  |..| ..|           ||.|.. .||||| .|.||...|| | | ||.|||.|| |             .|.|||| .|..|. ... .|.  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTPFFMAPQLLN----NQPYT-TKSDIWSLGITLFFMLFKRLPWDEKVQKQHQLR--QFITN-------EYD-PDKFFSHC-TNVISEFTLS
        ||| .||||.|.    ..||.  |.||||||. .. ||. . |. .    . .|.  . | |       ... | .| . .  ..||. . .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LLKRMIVVDEEKRISWEELFK
|..||...||..||||||.|.
LIRRMLQYDEKDRISWEEIFN

Kinase 28438.AA ULK 15-267 31 6.3e-87 295.1 In-house 1-325 (329) Show / Hide
Range on Protein: 15-267
Range on HMM: 1-325/329
Sequence Identity: 31% (102 aa)

VDESKLLGSGNCGSVYFGWKTDNT---EQYLAIKQIP----INSKFE-----ITDSMLIEINLLRRLD--------HPNIVKFIDAKKTKDF--MYLIME
   .. ||.|  | || | . ..     .. |.|.|.    .... |     . ..   || ....|.        ||||||..| ..|...   |.|||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCNEGSIEDLIINQK-----------VSENEVLDYFKQICKAFRELNNKNILHGDVKPSNILLHNSQ-------------CKLADFGVSKTIDK----KS
.|| |  |..| ..|            ||.|.. .||||. .|.||. .|| | | ||.|||.|| |             .|.|||| .|..|.    . 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

ENTTMR------GTPFFMAPQLLN----NQPYT-TKSDIWSLGITLFFMLFKRLP---WDEKVQKQHQLRQFITNEYDPD----KFFSHCT-----NVIS
 ..|.       ||| .||||.|.    ..||.  |.||||||. .. ||. . |   |    |.  .... | |.. .     |.   .      ..||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

EFTLSLLKRMIVVDEEKRISWEELFK
. . .|..||...||..||||||||.
PECKDLIRRMLQYDEKDRISWEELFN

Kinase 28438.AA Ciliate-E2 15-271 24 3e-84 286.21 In-house 1-365 (365) Show / Hide
Range on Protein: 15-271
Range on HMM: 1-365/365
Sequence Identity: 24% (92 aa)

VDESKLLGSGNCGSVYFG--WKTDN--------------------TEQYLAIKQIPINSKFEIT--DSMLIEIN----------LLRRLDHPNIVKFIDA
 .  |..|.|| |||| .  ||...                    . .. |.|..  | ...|   .... |||          .|..|.||||.|....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

KK--TKDFMYLIMEFCNEGSIEDLIINQ------------KVSENEVLDYFKQICK---------------AFRELNNKN-ILHGDVKPSNILLHNSQCK
 .  ... .||.||.|. |. .|.|.|.            . .|.|.....|||..               |...| .|| |.| | ||.|||.    .|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK

LADFGVSKTIDKKSENTTM--------------------------------RGTPFFMAPQLLNNQP---------YTTKSDIWSLGITLFFMLFKRLPW
..||| || .|....|.|.                                 ||| .|||. ||...         |..|.||||||..|..|||...|.
IIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF

DEKVQKQHQLRQFITNEYDPDKFFSHC--------------TNVISEFTLSLLKR----MIVVDEEKRIS-WEELFKLVIP
            .. ..  . .|.. .              .. .|. .  |.|.    |...|.||||. ||....  . 
------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 28438.AA S_TKc 15-268 27 4.2e-70 240.13 SMART 1-231 (231) Show / Hide
Range on Protein: 15-268
Range on HMM: 1-231/231
Sequence Identity: 27% (74 aa)

VDESKLLGSGNCGSVYFGWKTDNTEQYLAIKQIPINSKFEITDSMLIEINLLRRLDHPNIVKFIDAKKTKDFMYLIMEFCNE--GSIEDLIINQK-----
 .  ...|.|  |.|| ..... | .. |||.|.        .... ||..|.. .||||||..|.  . |..|..||.|.   |.  |.| ...     
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--VSENEVLDYFKQICKAFRELNNKNILHGDVKPSNILLHNSQCKLADFGVSKTIDKKSENTTMRGTPFFMAPQLLNNQPYTT-KSDIWSLGITLFFMLF
   .| ..  |..|||.|   . ...|.| |.||.|||| . . |..|||... .      ||. |||..||| .|   .|.. |.|.||.|..|. || 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

KRLPWDEKVQKQHQLRQFITNEYDPDKFFSHCTNVISEFTLSLLKRMIVVDEEKRISWEELFK----------L
 . |..   | |  ...                   |.  ....... ..| |||..  |...          .
GYPPFP---QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 28438.AA Pkinase 15-269 26 4.4e-67 233.98 Pfam 1-293 (293) Show / Hide
Range on Protein: 15-269
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

VDESKLLGSGNCGSVYFGWKTDNTEQYLAIKQIPINSKFEITDSMLI---EINLLRRLDHPNIVKFIDAKKTKDFMYLIMEFCNEG----SIEDLII---
    . .|||. |.| .  .  .|..  |.|.|.  .. .  |  ..   || ...||.|||||...|.  .|| .|..||.|. |    .  |.|    
YHIGRKIGSGSFGCV-YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

NQKV--SENEVLDYFKQICKAFRELNNKNILHGDVKPSNILLH-NSQC----KLADFGVSKT--IDKKSENTTMRGTPFFMAPQLLN-NQPYTTKSDIWS
. ..  ||.|. .|..||...   . ...|.| |.||.|||.. | ..    |..|||..|   . ..| .||  |||..||| ... .|.|..|.|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGITLFFMLFKRLPWDEKVQKQHQLRQFITNEYDPD-KFFSHCTNVIS-------------------EFTLSLLKRMIVVDEEKRISWEELFKL--V
.|..|. ||..|.|......  . ..|    . . . .. ... . .|                   |  ....|... .| .||...|....   .
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 28438.AA CAMK 20-261 20 6.1e-61 194.79 In-house 1-415 (425) Show / Hide
Range on Protein: 20-261
Range on HMM: 1-415/425
Sequence Identity: 20% (85 aa)

LLGSGNCGSVYFGWKTDNTE-----------QYLAIKQIPINSKFE---------------------------ITDSMLIEINLLRR-------LDHPNI
 ||.|. | |. .  . .|            |  ||| |. .   .                             .... ||.....       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKFID---------------AKKT-----KDFMYLIM---EFCNEG----SIEDLIINQ----------------KVSENEVLDYFKQICKAFRELNNKN
.|...                 ..     ...||..|   |.|  |     . | |. .                ...| |.  ||.||| | . . ..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ILHGDVKPSNILL-HNS-----------------QCKLADFGVSKTIDKKSENT------------------------TMRGTPFFMA-PQLLNN-----
| | | || |||| .|.                 . |..||| .. .|....|.                        |. ||| .|| | .||      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------QPYTTKSDIWSLGITLFFMLFKRLPWDEKVQK------------QHQLRQFITNEYD-PDKFFSH-----------------CTNVISEFT
         ..|. |.|.||.|. |..||  ..|.... ..            .  ... .. .|| |...||.                     .|.  
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQEC

LSLLKRMIVVDEEKRIS
 .|...| .|| |||..
KDLIRKMLQVDPEKRMT

Kinase 28438.AA Ciliate-E2-Unclassified 16-271 24 7e-60 205.25 In-house 2-352 (352) Show / Hide
Range on Protein: 16-271
Range on HMM: 2-352/352
Sequence Identity: 24% (86 aa)

DESKLLGSGNCGSVYFGWKTDNTEQYLAIKQIP-------INSKFEITDSMLIEINLLRR------------------LDHPNIVKFIDAKKTKDFMYLI
   | .|.|. |.||   . ..  || |.|..         . .... . |.... . ..                  ..||.|||.......|. .|..
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEFCNEGSIEDLIIN------------------QKVSENEVL-----DYFKQICKAFRELNNKN-ILHGDVKPSNILLHNS----QCKLADFGVSKTID-
||.|. |. .. | .                  ....|....     .||.||....  |  || |.| | ||.|||..|.    ..|..||| || .. 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------KKSENTTMRGTPFFM----APQLLNNQPYT----TKSDIWSLGITLFFMLFKRLPWDEKVQKQHQ--------------LRQFI-
               |. . .|. ||| .|    || .| .| |      |.||||||. |..||| ..| . . ..|||              |.| | 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

TNEYDPDKFFS-----HCTNVISEFTLSLLKRMIVVDEEKRISWEELFKLVIP
 .... .||       |  .   .|   ||..|.... .|||..|....  . 
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 28438.AA STE 15-209 24 4e-59 202.75 In-house 1-268 (359) Show / Hide
Range on Protein: 15-209
Range on HMM: 1-268/359
Sequence Identity: 24% (67 aa)

VDESKLLGSGNCGSVYFGWKTD-----NTEQY---------LAIKQIPINSK----------------FEITDSMLIEINLLRRLD--HPNIVKFIDAKK
 .  . .|.|..|.|| . . .      | .           ||||......                 |. .. | ||.......  ||||||....  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TK-------DFMYLIMEFCNEGSIEDLIIN---------------QKVSENEVLDYFKQICKA-FRELNNKNILHGDVKPSNILLHNSQCKLADFGVSKT
 .       |  ...||... ||..|.| .               ....|...  . .||.|.    | ...| | |.||.||||    .||.||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ

IDK-----------------KSENTTMRGTPFFMAPQLLNN------QPYTTKSDIWSLGITLFFMLFKRLPW
...                 .....|. ||| .|||  ...      ..|.||.||||||.|.  |.  . ||
LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPW

Kinase 28438.AA CAMKL 13-265 25 8.4e-55 173.25 In-house 1-291 (297) Show / Hide
Range on Protein: 13-265
Range on HMM: 1-291/297
Sequence Identity: 25% (77 aa)

YVVDESKLLGSGNCGSVYFGWKTDNTEQYLAIKQIPINSKF--EITDSMLI------------EINLLRRLD---HPNIVKFIDAKKTKDF------MYL
| . .   || |..| |  .. . .|..  ||| | .. .   ...... .            ||.....|.   ||||.|. .   |...      .||
YRIGK--TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYL

IMEFCNEGS--IEDLIINQ-----KVSENEVLDYFKQICKAFRELNNKNILHGDVKPSNILLHNSQ---CKLADFGVSKTIDK-----KSENTTMRGTPF
.|| |  |.    | |...     . .|.|   ||.||. |   . ...| | | || |||| ...    |..||| |  ...         .|  |.| 
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

FMAPQLLNN--QPYT-TKSDIWSLGITLFFMLFKRLPWDEK--------VQKQHQLRQFITNEYDPDKFFS-HCTNVISEFTLSLLKRMIVVDEEKRISW
.||| ...   .||   | ||||.|..|..|.. .||.|.          .    ... .. .|.|  ..   |         .|...| .|. |||.. 
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDC--------RDLIRKMLQVNPEKRPTI

EEL
...
HQI

Kinase 28438.AA STE11 15-196 28 3.3e-48 166.46 In-house 1-225 (303) Show / Hide
Range on Protein: 15-196
Range on HMM: 1-225/303
Sequence Identity: 28% (65 aa)

VDESKLLGSGNCGSVYFGWKTDNTEQYLAIKQIPINSKF-------EITDS------MLIEINLLRRLDHPNIVKFIDAKK---TKDFMYLIMEFCNEGS
  . ...|.|  |.|| .  .| | . .|.|||.|.          .. .|         ||.|.. |.|.|||......     .|... .||.| .||
WQKGEIIGKGAFGTVYKCMNVD-TGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGS

IEDLII-NQ---KVSENEVLDYFKQICKAFRELNNKNILHGDVKPSNILLHN-SQ-CKLADFGVSKTID-KKSENTT----------MRGTPF-------
.....  ..   | .|...  | |||...   |  ..| | |.|. ||||   .. ||||||| .| .    .....          |.|||.       
LSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTP

-FMAPQLLNNQP---YTTKSDIWSLG
 .|||  .....   |..|.||||||
MWMAPEVIKQEGRDGYGRKADIWSLG

Kinase 28438.AA Pkinase_Tyr 15-200 28 2.6e-24 82.97 Pfam 1-205 (270) Show / Hide
Range on Protein: 15-200
Range on HMM: 1-205/270
Sequence Identity: 28% (58 aa)

VDESKLLGSGNCGSVYFGWKT---DNTEQYLAIKQIPINSKFEI--TDSMLIEINLLRRL-DHPNIVKFIDAKK-TKDF--MYLIMEFCNEGSIEDLIIN
.   | ||.|. |.|| |  .   |||..  |.| .. ..  |    .... |..... | .|||||... .    ..   .|..||..  |.  |   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

Q-----KVSENEVLDYFKQICKAFRELNNKNILHGDVKPSNILLH-NSQCKLADFGVSKTIDKKSENT-TMRG---TPFF-MAPQLLNNQPYTTKSDIWS
.     ...  . |..  ||.|.   | .||. | |.   |.|.. | ..| .||| ...|  . ..  ..||    | . |||  .|.  .|||||.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

LGITLF
 |....
FGVLMW

Kinase 28438.AA TyrKc 15-269 19 7.6e-16 33.49 SMART 1-280 (280) Show / Hide
Range on Protein: 15-269
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

VDESKLLGSGNCGSVYFGWKTDNTEQYLAIKQIPINSKFEITDSMLIEINLLRRL--DHPNIVKFIDAKKTK-------DFMYLIMEFCNEGSIEDLIIN
.   | ||.|. | || |  .    .  |.| .  ..       .. |......|  .|||||... .  ..       . ....||..  |.  | . .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QK--VSENEVLDYFKQICKAFRELNNKNILHGDVKPSNILLHNSQ-CKLADFGVSKTIDKK------SENTTMR---GTP-----FFMAPQLLNNQPYTT
 .  ..  . |..  ||..  . |  ||. | |    |.|... . .| .||| |. |. .      ..  ...   |.        |||  .|   .||
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KSDIWSLGITLF--FMLFKRLPWD---EKVQKQHQLRQFITNEYDPDKFFSHCTNV----ISEFTLSLLKRMIVVDEEKRISWEELFKLV
|||.|| |....  | . .  ...   . . .  ...... . | ...  ...  .     ..   .. |.    | |.| . .|. .. 
KSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF