Gene 10685 (Tetrahymena)

10685

Species: Tetrahymena
Alias: 3723.m00028, 64.m00165, 357, TTHERM_00509000, PreTt10685, 10685
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
10685.AA Protein None 595 None Fasta, JSON
10685.kin_dom Protein Kinase Domain None 344 None Fasta, JSON
10685.NA RNA None 1788 None Fasta, JSON

Protein domain

Protein domains of 10685.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 10685.AA Ciliate-E2 49-392 20 1.8e-88 300.2 In-house 1-365 (365) Show / Hide 
Range on Protein: 49-392
Range on HMM: 1-365/365
Sequence Identity: 20% (95 aa)

IDKNGQLGQGGHASIYKLNEMSHDN------------------GKNSSRKCAKKFEKKNLFFKNSEIQSLK----------------SLDHPNIVKLYEY
.... ..|||...|.|| .  . ..                  . ... .  | ..|........||. ..                .|.||||.|.||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--ERDAFYIIMEEVQGRDLFDEMAERKRPFG----------ENDTCQIIQQVLQ---------------ALSYTHQKG-IIHRDIKLENIMVSQNHIQ
|.   .. .|..|| .|| |||| . ..|  ..          |.  ..|..|.||               || | |.|. |||||||.|||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

TANTYVQATNSIDQQEKCQGTEQSQNIERSLEENQNQFNTNSILNNKEDSKGQSQDTKYHTTEDQQIKLNSQNQLSQDDSQIEWRVKLIDWSFGTNRSQS
                                                                                     .|.||. . .. ...
-------------------------------------------------------------------------------------IKIIDFGLSKKYDDD

KTKFL------------------------------SSLCGSLMFQAPEYFDKK----------YTEKIDIWALGVVMYTMLANRYPFGQNCKSKLQIQTQ
  . .                               ..||.....||| . .|          |..|.|||.|||..| || ...||          | |
NQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------QQQ

IQKEQVVFGKE---------------WDTISDEAKDLINK----MLEKNPEKRPS-AQELLNHVWF
|.. .. | ..               |. .|.|.||||.|    ||.|.||||.. ....||| ||
IKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 10685.AA Ciliate-E2-Unclassified 49-392 22 9e-84 284.62 In-house 1-352 (352) Show / Hide 
Range on Protein: 49-392
Range on HMM: 1-352/352
Sequence Identity: 22% (96 aa)

IDKNGQLGQGGHASIYKLNEMSHDNGK------NSSRKCA-KKFEKKNLFFKNS--EIQSLK----------------SLDHPNIVKLYEYFEERDAFYI
  .. |.||||....||. . ...  .      ....... |. ..|.  ..|.  |....|                ...||.|||....|. .. .||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMEEVQGRDLFDEMAERK----------------RPFGENDTC-----QIIQQVLQALSYTHQKG-IIHRDIKLENIMVSQNHI--QTANTYVQATNSID
.|| ..| ||.. . .||                . | |. ..     ... |.||.|.| |.|. |||||||.|||....|.   .   .  .    ..
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

QQEKCQGTEQSQNIERSLEENQNQFNTNSILNNKEDSKGQSQDTKYHTTEDQQIKLNSQNQLSQDDSQIEWRVKLIDWSFGTNRSQSKTKFLSSLCGSLM
|...|. |.|                                                               .       ..... | . ... ||...
QNNNCD-TNQ---------------------------------------------------------------Q-------QKMQIWKQQMMWTFCGTPN

FQ----APEYFDK-KYT----EKIDIWALGVVMYTMLANRYPFGQNCKSK---------------LQIQTQIQKEQVVFGKEW----DTISDEAKDLIN-
..    |||.... .|     .|.|||.|||..| || ..|||..|.. .                ..| ..||.. ..  .|    ...|.||||.|| 
YMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIND

---KMLEKNPEKRPSAQELLNHVWF
   |||.|||.||......||| ||
LLQKMLKKNPNKRITFEQILNHPWF
Kinase 10685.AA Ciliate-E2a 96-392 29 3.5e-79 232.73 In-house 49-275 (275) Show / Hide 
Range on Protein: 96-392
Range on HMM: 49-275/275
Sequence Identity: 29% (90 aa)

EIQSLKSLDHPNIVKLYEYFEERDAFYIIMEEVQGRDLFDEMAERKRPFGE-NDTCQIIQQVL-QALSYTHQKGIIHRDIKLENIMVSQNHIQTANTYVQ
||. ...|||||| ||||..|  . .|..|| ..|..|.|.. . || | | .. |.|.|| | |.|.| ||..|.|||.|.|||.              
EINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKN-----------

ATNSIDQQEKCQGTEQSQNIERSLEENQNQFNTNSILNNKEDSKGQSQDTKYHTTEDQQIKLNSQNQLSQDDSQIEWRVKLIDWSFGTNRSQSKTKFLSS
                                                             ......   ..|.|    |.||. ..|. .. . |.. .
-------------------------------------------------------------CSKNSI---QNSDI----KIIDFGLATFIDKDEKKYMFQ

LCGSLMFQA------PEY-FDKKYTEKIDIWALGVVMYTMLANRYPFGQNCKSKLQIQTQIQKEQVVF-GKE-WDTISDEAKDLINKMLEKNPEKRPSAQ
 ||.  . |      .|  ..|.|..| |.| .||..|..|  . ||  . |.  .|  |. | .  | ..| |  .|.|.|||. |||||.|.||..||
KCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPF--KGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQ

ELLNHVWF
..||| ||
QALNHPWF
Kinase 10685.AA CAMK-Unique 96-392 24 1.1e-66 219.09 In-house 66-363 (363) Show / Hide 
Range on Protein: 96-392
Range on HMM: 66-363/363
Sequence Identity: 24% (90 aa)

EIQSLKSLDHPNIVKLYEY----FEERD---------------AFYIIMEEVQGRDLFDEMAER-------------------KRPFGE--NDTCQIIQQ
|.| .|..|||||.|||..    |. |.               ..||.|| .||.||||.....                   ...| |  .|||.|.|.
EHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQC

VLQALSYTHQKGIIHRDIKLENIMVSQNHIQTANTYVQATNSIDQQEKCQGTEQSQNIERSLEENQNQFNTNSILNNKEDSKGQSQDTKYHTTEDQQIKL
.|.|..| |...|.|||.|||||||. . .                                                                      
LLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNN-------------------------------------------------------------------

NSQNQLSQDDSQIE---WRVKLIDWSFGTNRSQSKTK-FLSSLCGSLMFQAP--------------EYFD-KKYTEKI----DIWALGVVMYTMLANRYP
      .  |. .    |..||.|.   .  ...|    ... ||.... ||              |  .  .| ..     |||.|||.||.||  . |
------HHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPP

FGQNCKS------KLQIQTQIQKEQV-VFGKE-WDT---ISDEAKDLINKMLEKNPEKRPSAQELLNHVWF
|  .|.       .  |   | | ..  | .. |.    ||.||||.. . ..  | .| || ||| | |.
FDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 10685.AA Pkinase 49-392 24 5.1e-64 223.78 Pfam 1-293 (293) Show / Hide 
Range on Protein: 49-392
Range on HMM: 1-293/293
Sequence Identity: 24% (94 aa)

IDKNGQLGQGGHASIYKLNEMSHDNGKNSSRKCAKKFEKKNLFFKN-------SEIQSLKSLDHPNIVKLYEYFEERDAFYIIMEEVQGR----DLFDEM
. . ...|.|. .. ||   . ...||   . . |...|..   .        |||| .|.|.|||||.||..||..|  |..|| ..|     |||| .
YHIGRKIGSGSFGCVYKC--HHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

A-ERKRPF--GENDTCQIIQQVLQALSYTHQKGIIHRDIKLENIMVS-QNHIQTANTYVQATNSIDQQEKCQGTEQSQNIERSLEENQNQFNTNSILNNK
  .|...|   |.. . .. |.|..| | |..||||||.|.|||... ..|| .                                              
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA----------------------------------------------

EDSKGQSQDTKYHTTEDQQIKLNSQNQLSQDDSQIEWRVKLIDWSFGTNRS--QSKTKFLSSLCGSLMFQAPEY--FDKKYTEKIDIWALGVVMYTMLAN
                                     .||..|  ||  .     .   ....||.. . |||   ....|. |.|.|..|...| ||  
-------------------------------------CVKICD--FGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCG

RYPFGQNC-----KSKLQIQTQIQKEQVVFG-KEWDTIS-----------------DEAKDLINKMLEKNPEKRPSAQELLNHVWF
| ||  ..      ...|.  .| . .. |   .|..||                 .|.||.|...|.|.|.|||.|...|.| ||
RPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 10685.AA S_TKc 49-392 25 1.1e-63 218.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 49-392
Range on HMM: 1-231/231
Sequence Identity: 25% (91 aa)

IDKNGQLGQGGHASIYKLNEMSHDNGKNSSRKCAKKFEKKNLFFKNSEIQSLKSLDHPNIVKLYEYFEERDAFYIIMEEVQG--RDLFDEMAERKRP---
 ..  ..|.|. .. ||  . .      . |..| |  |       .||| ||. .||||||||..|.. | .|..|| . |   |||| . .|.|.   
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FGENDTCQIIQQVLQALSYTHQKGIIHRDIKLENIMVSQNHIQ-----TANTYVQATNSIDQQEKCQGTEQSQNIERSLEENQNQFNTNSILNNKEDS
  | | ... ...|...|| | |..||||||.| |||.... ||       |  .                                             
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL---------------------------------------------

KGQSQDTKYHTTEDQQIKLNSQNQLSQDDSQIEWRVKLIDWSFGTNRSQSKTKFLSSLCGSLMFQAPEYFDKKYTE-KIDIWALGVVMYTMLANRYPFGQ
                                                       ...||.. . ||| .  .|.  |.|.|..|...| ||. . ||  
-------------------------------------------------------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP-

NCKSKLQIQTQIQKEQVVFGKEWDTISDEAKDLINKMLEKNPEKRPSAQELLN-------HVWF
      |.|. ..|            |.||||.|.|.|.|.|||||.| |.|.       | ||
------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 10685.AA CAMK 269-392 23 2.5e-41 130.43 In-house 226-425 (425) Show / Hide 
Range on Protein: 269-392
Range on HMM: 226-425/425
Sequence Identity: 23% (47 aa)

E------WRVKLIDWSFGTNRSQSK----------------------TKFLSSLCGSLMFQA-PEYFDKK---------------YTEKIDIWALGVVMY
|      . .|.||. | .   ...                      .. ..  ||.. . | || . .|               |..|.|.|..||..|
EIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILY

TMLANRYPFGQNCK-----------SKLQIQTQIQKEQVVFGKE-------------WDTISDE--------AKDLINKMLEKNPEKRPSAQELLNHVWF
.||  ..||   |            .  ..  .|.| .  |  .             || ||||        .||||.|||...||||..... ||| |.
IMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 10685.AA CDPK 264-392 43 3.7e-38 114.76 In-house 141-271 (271) Show / Hide 
Range on Protein: 264-392
Range on HMM: 141-271/271
Sequence Identity: 43% (59 aa)

DDSQIEWRVKLIDWSFGTNRSQSKT-----KFLSSLCGSLMFQAPEYFDKKYTEKIDIWALGVVMYTMLANRYPFGQNCKSKLQIQTQIQKEQVVFG-KE
|||..   .|.|||  || . . .      | .|  ||     |||  .||| || ||| .||..|..|  . ||  . |.  .|. ...| .  |  .|
DDSWVIYNIKVIDW--GTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDIWSCGVILYILLCGYPPF--YGKNDQEIMEKVKKGKYSFEGPE

WDTISDEAKDLINKMLEKNPEKRPSAQELLNHVWF
|| |||||||||.|||...|.|| |||. |.| ||
WDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 10685.AA CDPK 96-184 41 6.4e-38 114.04 In-house 51-140 (271) Show / Hide 
Range on Protein: 96-184
Range on HMM: 51-140/271
Sequence Identity: 41% (38 aa)

EIQSLKSLDHPNIVKLYEYFEERDAFYIIME--EVQGRDLFDEMAERKRPFGENDTCQIIQQVLQALSYTHQKGIIHRDIKLENIMVSQNH
||  ||.||||||.|.||... .. .||.||   . | .|||  .|... | | ....|..|.|.|..| |...|.|||.| |||.  ...
EIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGH-FTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKK
Kinase 10685.AA CAMK 54-184 20 1.1e-35 112.0 In-house 1-216 (425) Show / Hide 
Range on Protein: 54-184
Range on HMM: 1-216/425
Sequence Identity: 20% (45 aa)

QLGQGGHASIYKLNEMSHDNGKNS------SRKCAKKF--------------------------------EKKNLFFKNSEIQSLKS-------LDHPNI
.||.|. .  ..  . .  . ...       .|.| |.                                . |.. .  .||. .|.       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLYEYFEE-------------------RDAFYIIM---EEVQGR----DLFDEMAER--------------KRPFGENDTCQIIQQVLQALSYTHQKGI
.||||..|                    .. .|..|   | ..|     ||||   |.              .. | | .......|...|. | |...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKLENIMVSQNH
.|||.|.|||....|.
VHRDLKPENILLDDNN
Kinase 10685.AA CAMKL 96-185 35 6.1e-35 108.84 In-house 62-168 (297) Show / Hide 
Range on Protein: 96-185
Range on HMM: 62-168/297
Sequence Identity: 35% (38 aa)

EIQSLKSLD---HPNIVKLYEYFEERDA------FYIIMEEVQGRD--LFDEMAERK---RPFGENDTCQIIQQVLQALSYTHQKGIIHRDIKLENIMVS
||| .|.|.   ||||.|||| .| ..       .|..|| ..| .  |||   ...   ... |...... .|.. |..| |..||.|||||.|||...
EIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLD

QNH---I
.|.   |
ENGNNNI
Kinase 10685.AA CAMKL 289-392 33 1.7e-32 100.88 In-house 188-297 (297) Show / Hide 
Range on Protein: 289-392
Range on HMM: 188-297/297
Sequence Identity: 33% (38 aa)

KFLSSLCGSLMFQAPEYFDK--K-YT-EKIDIWALGVVMYTMLANRYPFGQN-----CKSKLQIQTQIQKEQVVFGKEWDTISDEAKDLINKMLEKNPEK
..|.  |||. ..||| | .  | |   |.|||..||..|.|.  ..|| .       |.       .....  .   |  .| ...||| |||..||||
QKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEK

RPSAQELLNHVWF
||......|| |.
RPTIHQIMNHPWM
Kinase 10685.AA CAMK1 96-178 45 3.7e-31 87.79 In-house 55-139 (276) Show / Hide 
Range on Protein: 96-178
Range on HMM: 55-139/276
Sequence Identity: 45% (39 aa)

EIQSLKS---LDHPNIVKLYEYFEERDAFYIIMEEVQGRDLFDEMAERKRPFGENDTCQIIQQVLQALSYTHQKGIIHRDIKLENI
||. .|.   .|||||.|.||..|. . ||..|| |.| .|||   |..  . |.| . |..|.|.|. | |.||| |||.| ||.
EIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIVEKG-NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENL
Kinase 10685.AA MARK 95-183 38 5.4e-31 98.69 In-house 48-140 (262) Show / Hide 
Range on Protein: 95-183
Range on HMM: 48-140/262
Sequence Identity: 38% (36 aa)

SEIQSLKSLDHPNIVKLYEYFE--ERDA-FYIIMEEVQGRDLFDEMAER-KRPFGENDTCQIIQQVLQALSYTHQKGIIHRDIKLENIMVSQN
.||. .|.||||||.||....|  ..   .|.||| . | .|.| . .. ...  |... .| .|.. |..| |.|.|.|||||.|||.. .|
REIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDEN
Kinase 10685.AA MARK 291-392 33 4.2e-30 95.74 In-house 162-262 (262) Show / Hide 
Range on Protein: 291-392
Range on HMM: 162-262/262
Sequence Identity: 33% (35 aa)

LSSLCGSLMFQAPEYFDKKYTE--KIDIWALGVVMYTMLANRYPFGQNCKSKLQIQTQIQKEQVV-FGKEWDTISDEAKDLINKMLEKNPEKRPSAQELL
|.. ||.. . ||| | ||  .  |.|||.||||.|.|.  ..||   ...  ... .|....   . .    .|.|...||...|  |||.||...|..
LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIM

NHVWF
.| |.
KHPWM
Kinase 10685.AA RSK 271-392 32 1.5e-29 104.47 In-house 145-278 (278) Show / Hide 
Range on Protein: 271-392
Range on HMM: 145-278/278
Sequence Identity: 32% (43 aa)

RVKLIDWSFGTNRSQSKTKFLSSLCGSLMFQAPEYFD----KK-YTEKIDIWALGVVMYTMLANRYPFGQ-NCKSKLQIQTQIQKEQ-VVFGKEWDTISD
..||.|  |   .. .... . . |... . |||       .. ...  |.| |||.||.||. . || . | ... .| ..||| .  . ...|...|.
HIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQ

EAKDLINKMLEKNPEKRPS-----AQELLNHVWF
||||||.|||...|.||..     |.|...| ||
EAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 10685.AA RSK 96-179 36 5.5e-23 81.07 In-house 50-136 (278) Show / Hide 
Range on Protein: 96-179
Range on HMM: 50-136/278
Sequence Identity: 36% (32 aa)

EIQSLKSLD-HPNIVKLYEYFEERDAFYIIMEEVQGRDLFDEMAERKRP--FGENDTCQIIQQVLQALSYTHQKGIIHRDIKLENIM
|.. |.    ||.||.|.. |.. . .|.||| . | .||.   ..|.   | |.. |... ..  |... ||.||||||.|.|||.
ERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENIL
Kinase 10685.AA CAMK1 357-392 51 2.4e-22 61.73 In-house 240-276 (276) Show / Hide 
Range on Protein: 357-392
Range on HMM: 240-276/276
Sequence Identity: 51% (19 aa)

EWDTISDE-AKDLINKMLEKNPEKRPSAQELLNHVWF
.|| |||. |||.|..|||..|.||..... ||| |.
WWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 10685.AA TyrKc 49-390 17 4.9e-10 -60.43 SMART 1-280 (280) Show / Hide 
Range on Protein: 49-390
Range on HMM: 1-280/280
Sequence Identity: 17% (67 aa)

IDKNGQLGQGGHASIYK--LNEMSHDNGKNSSRKCAKKFEKKNLFFKN---SEIQSLKSL--DHPNIVKLYEYFEER-------DAFYIIMEEVQGRDLF
| .. .|| |    .||  ..           ...| |  |..   .    .|.. ...|  .|||||.|| .  .        .  .|.|| . . || 
ITLGKKLGEGAFGEVYKGTWK-----------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

DEMAERKRPFGENDTCQIIQQVLQALSYTHQKGIIHRDIKLENIMVSQNHIQTANTYVQATNSIDQQEKCQGTEQSQNIERSLEENQNQFNTNSILNNKE
|   .... .   | ...  |. .  .| |.|..||||.   |..|. ||                                                  
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--------------------------------------------------

DSKGQSQDTKYHTTEDQQIKLNSQNQLSQDDSQIEWRVKLIDWSFGTNRSQSKT-------KFLSSL---CGSLMF----QAPEYF-DKKYTEKIDIWAL
                                    .||  |  ||  |            .  ..    .|  |.     ||| . ..|.|.| |.|. 
------------------------------------TVKISD--FGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSF

GVVMY--TMLANRYPFG---QNCKSKLQIQTQIQKEQVVFGKEWD------TISDEAKDLINKMLEKNPEKRPSAQELLNHV
||.|.    .    . |   |  .|  ..  ....       . |      . .||  ... .  . .||.||. .|.    
GVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 10685.AA Pkinase_Tyr 95-185 31 2.2e-09 32.4 Pfam 52-149 (270) Show / Hide 
Range on Protein: 95-185
Range on HMM: 52-149/270
Sequence Identity: 31% (31 aa)

SEIQSLKSL-DHPNIVKLYEYFE-ERDA--FYIIMEEVQGRDLFDEMAER---KRPFGENDTCQIIQQVLQALSYTHQKGIIHRDIKLENIMVSQNHI
.|.. .|.| .|||||.||     ...    ||.|| ... || |   ..   |.|.   | .|. .|. ....| ..|..||||.   |..|. |..
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNV
Kinase 10685.AA CAMK1 290-327 30 1.2e-08 21.15 In-house 169-210 (276) Show / Hide 
Range on Protein: 290-327
Range on HMM: 169-210/276
Sequence Identity: 30% (13 aa)

FLSSLCGSLMFQAPEYFDKK----YTEKIDIWALGVVMYTML
...  ||.. ..||| .  |    |  ..|.|  ||. |..|
LMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYILL
Kinase 10685.AA Pkinase_Tyr 374-390 29 0.566365 3.92 Pfam 254-270 (270) Show / Hide 
Range on Protein: 374-390
Range on HMM: 254-270/270
Sequence Identity: 29% (5 aa)

EKNPEKRPSAQELLNHV
...||.||. .|.... 
HYDPEDRPTFSEIHEQL
Kinase 10685.AA Pkinase_Tyr 306-324 42 0.899233 3.24 Pfam 187-205 (270) Show / Hide 
Range on Protein: 306-324
Range on HMM: 187-205/270
Sequence Identity: 42% (8 aa)

FDKKYTEKIDIWALGVVMY
...|.|.| |.|. ||.|.
NYGKFTTKSDVWSFGVLMW
Efhand 10685.AA efhand 444-472 31 4e-06 26.8 Pfam 1-29 (29) Show / Hide 
Range on Protein: 444-472
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

ELENLFKRLDTNQDGRLSKEEIMNGFNQI
||...|| .|...||....|| .... ..
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 10685.AA EFh 444-472 24 3.9e-05 24.31 SMART 1-29 (29) Show / Hide 
Range on Protein: 444-472
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

ELENLFKRLDTNQDGRLSKEEIMNGFNQI
|.. .|. .|.. ||....|| . ..  .
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 10685.AA efhand 482-510 24 0.00531 15.4 Pfam 1-29 (29) Show / Hide 
Range on Protein: 482-510
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

QINLIFDQVDSDKSDSIDYSEFITATLER
... .|...| |..  ||. ||...  . 
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 10685.AA EFh 482-510 24 0.014596 11.3 SMART 1-29 (29) Show / Hide 
Range on Protein: 482-510
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

QINLIFDQVDSDKSDSIDYSEFITATLER
... .|. .| |..  ||. ||...  . 
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 10685.AA efhand 518-546 34 5.7e-07 29.93 Pfam 1-29 (29) Show / Hide 
Range on Protein: 518-546
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

YLQKAFNLFDQDGDGHITKDEILKIIGNA
 |...|..||.|||| |...| .... . 
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 10685.AA EFh 518-546 31 7.3e-07 30.05 SMART 1-29 (29) Show / Hide 
Range on Protein: 518-546
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

YLQKAFNLFDQDGDGHITKDEILKIIGNA
 ....|..||.|||| |...| .... . 
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
EFh 10685.AA EFh 558-586 27 2.1e-07 31.87 SMART 1-29 (29) Show / Hide 
Range on Protein: 558-586
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

QIQQIIQQIDINQDGKIQFEEFCSIIQQF
....... .| . ||.| ||||. ... .
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 10685.AA efhand 558-586 31 2.5e-07 31.22 Pfam 1-29 (29) Show / Hide 
Range on Protein: 558-586
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

QIQQIIQQIDINQDGKIQFEEFCSIIQQF
.........| ..||.| |||||......
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL