Gene 16220 (Tetrahymena)

16220

Species: Tetrahymena
Alias: TTHERM_00841360, 308, PreTt16220, 3741.m00018, 16220, 147.m00072
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
16220.AA Protein None 561 None Fasta, JSON
16220.kin_dom Protein Kinase Domain None 267 None Fasta, JSON
16220.NA RNA None 1686 None Fasta, JSON

Protein domain

Protein domains of 16220.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 16220.AA Ciliate-E2 10-276 23 2e-82 280.12 In-house 1-365 (365) Show / Hide 
Range on Protein: 10-276
Range on HMM: 1-365/365
Sequence Identity: 23% (91 aa)

YIKQKQIGGGQYGKVFEAKDKQNVFQN-----------------IAIKQVNLQYVRPNEKEIWKQIKGQY-----------------------VVELYDC
|...|.|| |..|.|...|....  |                   .||.... ....|..|..||.. ..                       ....|.|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VQ--DEQNMYFIMEKCEGGNLQKYIEDSSKQANKQ------LTQYQILDLFYKIVKGYK--------------ESLYENN-IIHRDLKPENIMIHEGNPK
 |  |..|.|..|| |.||.|..||....|. |..      .| ..|......|..|.|              |.| ..| |||||.|||||..    .|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK

ITDFGMTLKYINPYD------------------------------MIQFSVAGTPKYAPPEAKSSDKLGN--------YIFDIYSLGCILYFCLYSNTPQ
|.|||.  || ....                              .......||| | .||  .. | .|        |  ||.|||.|||..|. ..| 
IIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF

SPTTYNQLNEFHECLKTQGPLAIAFPNRNVNGTVEIVDQPIK------------DLIQR----MIVYQQNQRLT-IDEVLNHPAF
            .  . |... . .|. . . |  .. | .|            |||..    |.......|.| ....|||| |
------------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 16220.AA Ciliate-E2-Unclassified 10-276 25 2.6e-79 269.81 In-house 1-352 (352) Show / Hide 
Range on Protein: 10-276
Range on HMM: 1-352/352
Sequence Identity: 25% (90 aa)

YIKQKQIGGGQYGKVFEAKD-KQNVFQ-----NIAIKQVNLQYVRP-----NEKEIWKQIKGQYVVE--------------------LYDCVQDEQNMYF
|...|||| |..|||..... ||. ..     .. |.... ....      ||.......|. |...                    ...| ||.||.|.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMEKCEGGNLQKYIEDSSK------------QANKQLTQYQIL-----DLFYKIVKGYKESLYENNIIHRDLKPENIMIHEG----NPKITDFGMTLKYI
.||.||||.|..||....|            . .|..| .|..     ..|. |..| .   ..|||||||.|||||.....    ..||.|||   ||.
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

NP--------------YDMIQFSVAGTPKYA----PPEAKSSDKLGN---YIFDIYSLGCILYFCLYSNTPQSPTTYNQLN-------------EFHECL
..              ..... ...||| |     .||   . . ..   |  ||.|||.|||..|. . | . ....| .             ....  
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KTQGPLAIAFPN----RNVNGTVEIVDQPIKDLIQRMIVYQQNQRLTIDEVLNHPAF
| . .    ||.     ... ...   .   ||.|.|.....|.|.|....|||| |
KQKNIQFPKFPWQQIPKHWSPEAKDFIN---DLLQKMLKKNPNKRITFEQILNHPWF
Kinase 16220.AA ULK 10-276 29 2e-63 217.02 In-house 1-324 (324) Show / Hide 
Range on Protein: 10-276
Range on HMM: 1-324/324
Sequence Identity: 29% (98 aa)

YIKQKQIGGGQYG-KVFEAKDKQN--VFQNIAIKQVNLQYVRP---------------NEKEIWKQIK---GQY--VVELYDCVQDE--QNMYFIMEKCE
|.. ...| |..| ||.....|..  . | .|.|...... .                || .|.|..|   ...  .|.|||. ..    | |.||| |.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGNLQKYIEDSSKQ----ANKQLTQYQILDLFYKIVKGYKESLYENNIIHRDLKPENIMIHEGNPK-------------ITDFGMTLKYINPYDMIQFSV
||.|..||.   |.     .| |.. ...  |. |. |.|| |...||||||.||.||.||.|.||             |.|||   | .. ..| |.  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKE-LHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA-KHVDNNNMEQQMC

A---------GTPKYAPPEAKSSD--KLGNYIF--DIYSLGCILYFCLYSNTP-QSPTTYNQLNEFHECLKTQG--------PLAIAFPNRNVNGTVEIV
          ||| |  |.  ..   .   | .  ||.|||||.| .||  .| .|.  ..| .  .. |. .|           | ||. .      ..
QTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPP---KDPKI

DQPIKDLIQRMIVYQQNQRLTIDEVLNHPAF
 . .||||.||..|....| ...|..||| |
SPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 16220.AA ULK 10-276 28 3.3e-61 209.64 In-house 1-329 (329) Show / Hide 
Range on Protein: 10-276
Range on HMM: 1-329/329
Sequence Identity: 28% (95 aa)

YIKQKQIGGGQYGKVFEAKDKQN---VFQNIAIKQVNLQYVRP---------------NEKEIWKQIK----GQY----VVELYDCVQDE--QNMYFIME
|.. ...| |..|||.....|..   | . .|.|.. .|. .                || .|.|..|    ...    .|.|||. ..    | |.|||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

KCEGGNLQKYIEDSSKQ-----ANKQLTQYQILDLFYKIVKGYKESLYENNIIHRDLKPENIMIHEGNPK-------------ITDFGMTLKYINP----
 |.||.|..||.   |.      .| |.. ...  |. |. |.|| |...||||||.||.||.||.|.||             |.|||   .  |.    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKE-LHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

YDMIQFS----VAGTPKYAPPEAKSSD--KLGNYIF--DIYSLGCILYFCLYSNTP-QSPTTYNQLNEFHECLKTQGPLA---IAFPNRNVNG--TVEIV
 .|  ..    . ||| |  |.  ..   .   | .  ||.|||||.| .||  .| ...  . | . ... |. ..|     |   . . .      ..
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

DQPIKDLIQRMIVYQQNQRLTIDEVLNHPAF
 . .||||.||..|....| ...|..||| |
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 16220.AA S_TKc 10-276 27 7.1e-53 182.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-276
Range on HMM: 1-231/231
Sequence Identity: 27% (76 aa)

YIKQKQIGGGQYGKVFEAKDKQNVFQNIAIKQVNLQYVRPNEKEIWKQIKGQYVVELYDCVQDEQNMYFIMEKCEG--GNLQKYIEDSSKQ-ANKQLTQY
| . ..|| | .|||. ...|    .  |||...      .| .| |. .  ..| |||. || ...|..|| |.|  |.| .||..  ..  .....  
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-

QILDLFYKIVKGYKESLYENNIIHRDLKPENIMIHEGNPKITDFGMTLKYINPYDMIQFSVAGTPKYAPPEAKSSDKLGNYIF---DIYSLGCILYFCLY
..  ..| |...  | . ...|||||||||||.. | . ||.|||.  ..         .. ||| | .||         | .   |..|.||||| .|.
HARFYMYQICCAL-EYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL--------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYEMLC

SNTPQSPTTYNQLNEFHECLKTQGPLAIAFPNRNVNGTVEIVDQPIKDLIQRMIVYQQNQRLTIDEVLN-------HPAF
  .| .    ..   |. ..                      ... ||.|... ..  ..|.|. |.|.       || |
GYPPFP----QMQMMFKKIG----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 16220.AA Ciliate-E2c 10-276 26 8.1e-42 144.37 In-house 1-310 (310) Show / Hide 
Range on Protein: 10-276
Range on HMM: 1-310/310
Sequence Identity: 26% (85 aa)

YIKQKQIGGGQYGKVFEA----------KD---------KQNVFQNIAIKQVNLQYVR---PNEKEIWKQIKGQYVVELYDCVQDEQNMYFIMEKCEGGN
. . .  | |.||||. |          .          |   ..|. |.. |.  .     .| .. |. .  .... || .| ... |.||| |.||.
IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT

LQKYIEDSSKQANK-QLTQYQILDLFYKIVKGYKESLYEN-NIIHRDLKPENIMIHEGNPKITDFGMTLKYINPYDMIQFSV-----AGTPKYAPPEAKS
|..||.      .| ...  |.|..|  |. . |. |... ||.|||.||||| ||.| .|| |||   | ... | ||.       .||| |  |.. .
LEQYIY------HKPKPNEKQCLYYFSQIISAFKY-LHKEKNIFHRDIKPENILIHNGMIKIADFGFS-KICQD-DNIQNTQGFNTCCGTPMYMAPQILE

SDKLGNYIF---DIYSLGCILYFCLYSNTPQS-----------PTTYNQLNEFHECLKTQGPL---------AIAFPNRNVNGTVE---IVDQPIKDLIQ
.   .||     || |||. ||. |. . |              . | .  . .. ||               .. ...|...  .    ..| .|.||.
G---KNYYTEKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIH

RMIVYQQNQRLTIDEVLNHPAF
.|...  . |.  ||. ||. .
KMLQVDEEKRIDWDEIFNHECI
Kinase 16220.AA Pkinase 10-276 25 2.8e-36 129.36 Pfam 1-293 (293) Show / Hide 
Range on Protein: 10-276
Range on HMM: 1-293/293
Sequence Identity: 25% (79 aa)

YIKQKQIGGGQYGKVFEAKDKQNVFQNIAIKQVNLQYVRP---------NEKEIWKQIKGQYVVELYDCVQDEQNMYFIMEKCEGG----NLQKYIEDSS
| . ..|| | .|.|.....| .  .  |.|.....  ..         .| .| | ..  ..|.|||...|....|..|| ||||     |  ||.   
YHIGRKIGSGSFGCVYKCHHKGTG-KIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

KQANKQL--TQYQILDLFYKIVKGYKESLYENNIIHRDLKPENIMIH-EGNP----KITDFGMTLKY-INPYDMIQFSVAGTPKYAPPEAKSSDKLGNYI
 .... .  .  .. . .| |..|  | .....|||||||||||.|. .|..    ||.|||   .. . ..     ...||| |..||          |
-WRHGCFYFSEWECKFYMYQILRGL-EYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEV---------I

F---------DIYSLGCILYFCLYSNTPQSPT----TYNQLNEFHECLKTQGPLAIAFPNRNVNG-----------TVEIVDQPIKDLIQRMIVYQQNQR
          |..|.|||||  |  ..| .      . .  .. . |.. ..||   .|. . .            |.  .... ||.| ... .  ..|
RGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMI-CRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKR

LTIDEVLNHPAF
.|....|.|| |
PTAEQILQHPWF
Kinase 16220.AA CAMK 15-202 19 1.1e-32 102.1 In-house 1-328 (425) Show / Hide 
Range on Protein: 15-202
Range on HMM: 1-328/425
Sequence Identity: 19% (63 aa)

QIGGGQYGKVFEAKDKQNVF-----------QNIAIKQVNL------------------------------QYVRP---NEKEIWKQ-------IKGQYV
..| |..|||.....|..             |  ||| ..                               .. |    .| || |.       ..   .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VELYDCVQD-------------------EQNMYFIM---EKCEGG----NLQKYIEDSSK---------QANKQ--LTQYQILDLFYKIVKGYKESLYEN
. ||.  .|                   ...||..|   | |.||     |  || . ..          . .   .|  .   .|  |. . .  . ..
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHY-CHSH

NIIHRDLKPENIMI-HE-----------------GNPKITDFGMTLKYIN----------------------PYDMIQFSVAGTPKYAP-PEAKSS----
||.|||||||||.. .                  .| ||.|||.  |..                        ..     . ||| |.. ||  ..    
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

----------DKLGNYIFDIYSLGCILYFCL
          .  |  . |. |.|.|||..|
NMQNATDEEKPYYGPKC-DMWSCGVILYIML
Kinase 16220.AA STE 10-198 23 2.7e-23 79.18 In-house 1-258 (359) Show / Hide 
Range on Protein: 10-198
Range on HMM: 1-258/359
Sequence Identity: 23% (62 aa)

YIKQKQIGGGQYGKVFEAKDKQNVFQN--------------IAIKQVNL--------------------QYVRPNEKEI--WKQIK--GQYVVELYDCVQ
. ....|| | .|.|. |... | . .              .||||.||                    . .   .|||   |. .   ...|. |.|  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DE-------QNMYFIMEKCEGGNLQKYIE---DSSKQAN------KQLTQYQILDLFYKIVKGYKESLYENNIIHRDLKPENIMIHEGNPKITDFGMTLK
.|       .. . .|| ..|| | . |.      |. |      . .   ||    . |.||  . | ...|||||.|| ||..     |..||| . .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFG-VCG

YINP--------------YDMIQF--SVAGTPKYAPPEAKSSDKLG-----NYIFDIYSLGCIL
 ...              ..| |   ...||| .  ||  . .. |     ..  ||.|||| .
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTI
Kinase 16220.AA CMGC 10-152 18 4.5e-22 68.5 In-house 1-250 (513) Show / Hide 
Range on Protein: 10-152
Range on HMM: 1-250/513
Sequence Identity: 18% (48 aa)

YIKQKQIGGGQYGKVFEAKDKQNVFQN-------------IAIKQVNLQYVRP-----------------NEKEIWKQIK-----------------GQY
| . |.|| | ||.|....||.. ..              .||| . ..   .                  | .| |...                   .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVELYDCVQDEQ-----------------NMYFIMEKCEGGNLQKYIEDSSK-----------------------QANKQLTQYQILDLFYKIVKGYK-E
.| |||......                 ..|...| ..  .| .||.. ..                       .  | ..  .|   .| | .| |  
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

SLYENN--IIHRDLKPENIMIHEGNP---------------------KITDFGM
 .  ..  |||||||||||.| . .                      || |||.
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGL
Kinase 16220.AA AGC 121-199 24 7.9e-20 46.52 In-house 167-296 (395) Show / Hide 
Range on Protein: 121-199
Range on HMM: 167-296/395
Sequence Identity: 24% (33 aa)

ESLYE-NNIIHRD-LKPENIMIHE-GNPKITDFGMTLKYINPY-------------------------------------------------DMIQFSVA
|.| . ..||||| ||||||.. | |. |.||||.  . .| .                                                 .    .  
EYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFC

G--TPKYAPPEAKSSDKLGNYIFDIYS--LGCILY
|  || | .||        ..  |..|  |||..|
GPCTPEYMAPEIL-----YGKACDWWSFGLGCLMY
Kinase 16220.AA CAMKL 125-203 34 2e-16 48.8 In-house 145-231 (297) Show / Hide 
Range on Protein: 125-203
Range on HMM: 145-231/297
Sequence Identity: 34% (30 aa)

ENNIIHRDLKPENIMIH-EG--NPKITDFGMTLKYI---NPYDMIQFSVAGTPKYAPPEAKSS--D-KLGNYIFDIYSLGCILYFCLY
...|.|||.|||||..   |  | ||.|||.  .|.   ....       |.| |..||  ..  .   |  . || |.| |||. ..
SHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKV-DIWSCGVILYAMVC
Kinase 16220.AA CAMKL 10-93 22 2.3e-15 45.34 In-house 1-115 (297) Show / Hide 
Range on Protein: 10-93
Range on HMM: 1-115/297
Sequence Identity: 22% (26 aa)

YIKQKQIGGGQYGKVFEAKDKQNVFQNIAIKQVN------LQYVRPN--------------EKEIWKQIK---GQYVVELYDCVQDEQN------MYFIM
|.  |..| | .|||  |.....  .  ||| ..       .... |              | .| |...    . .. ||........      .| .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EKCEGGN--LQKYIE
| |.||.  |. ||.
EYCSGGEMDLFDYIV
Kinase 16220.AA TyrKc 10-276 17 2.3e-11 -38.94 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-276
Range on HMM: 1-280/280
Sequence Identity: 17% (53 aa)

YIKQKQIGGGQYGKVFEAKDKQNVFQNIAIKQVNLQYVRPNEKEIW------KQI--KGQYVVELYDCVQDE-------QNMYFIMEKCEGGNLQKYIED
  . |..| |..|.|.... |    .. |.| ..       ....       ...  . . .| || .. ..       . .. .|| ...|.|..|. .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

SSKQANKQLTQYQILDLFYKIVKG--YKESLYENNIIHRDLKPENIMIHEGN-PKITDFGMTLKYINPY-------DMIQFSV--AGTP----KYAPPEA
. ..    |.  . |.  . | .|  |   | ..|.|||||   |....|..  ||.|||.. ..|  .       |..  .    |      .  .||.
HRPK----LCMKDLLSFCWQIACGMEY---LHSKNCIHRDLAARNCLVGENHTVKISDFGLS-RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

KSSDKLGNYIF----DIYSLGCILYFCLYSNTPQSPTTY----NQLNEFHECLKTQGPLAIAFPNRNVNGTVEI----VDQPIKDLIQRMIVYQQNQRLT
     .  ..|    |..| |  ..  ....  | .           | .|..|. . . .   .       ..      . . .....   .. ..| |
-----INYGKFTTKSDVWSFGVCMW-EIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY------PMSFVCCPDEMYQIMKQCWHEDPEDRPT

IDEVLNHPAF
  |.  |  |
FSEI--HECF
Kinase 16220.AA AGC 10-86 17 1.4e-09 19.4 In-house 1-127 (395) Show / Hide 
Range on Protein: 10-86
Range on HMM: 1-127/395
Sequence Identity: 17% (23 aa)

YIKQKQIGGGQYGKVFEAKDK--------QNVFQNIAIKQVNLQY---------VRPN--E------------KEIWKQIKG----------QYVVE-LY
.   | || | .|||. ...|        . ..   |.| .. ..         |. .  |            ..| .....          ...|  |.
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYY---AMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILH

DCVQDEQN--MYFIMEKCE---------GG
 . ||...   ||.|| ..         ||
YSFQDKDHTYLYFVMEYMPRYVNDLYCGGG
Kinase 16220.AA CAMK 245-276 43 8.4e-09 23.74 In-house 394-425 (425) Show / Hide 
Range on Protein: 245-276
Range on HMM: 394-425/425
Sequence Identity: 43% (14 aa)

VDQPIKDLIQRMIVYQQNQRLTIDEVLNHPAF
|.|  ||||..| ..  ..|.||...|||| .
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 16220.AA AGC 245-276 26 2.2e-08 16.27 In-house 354-395 (395) Show / Hide 
Range on Protein: 245-276
Range on HMM: 354-395/395
Sequence Identity: 26% (11 aa)

VDQPIKDLIQRMIVYQQNQRLT----------IDEVLNHPAF
...  ||||.....   ..||.          ..|. ||| |
FSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 16220.AA CMGC 251-276 38 3.6e-07 18.62 In-house 488-513 (513) Show / Hide 
Range on Protein: 251-276
Range on HMM: 488-513/513
Sequence Identity: 38% (10 aa)

DLIQRMIVYQQNQRLTIDEVLNHPAF
||...| .|  ..|.|... |.|| |
DLLKKMLQYDPDKRITAEQALQHPYF
Kinase 16220.AA CAMKL 245-276 34 4e-06 15.26 In-house 267-297 (297) Show / Hide 
Range on Protein: 245-276
Range on HMM: 267-297/297
Sequence Identity: 34% (11 aa)

VDQPIKDLIQRMIVYQQNQRLTIDEVLNHPAF
|. . .|||..| .   ..| ||....||| .
VS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 16220.AA Pkinase_Tyr 10-106 21 0.000216 15.5 Pfam 1-116 (270) Show / Hide 
Range on Protein: 10-106
Range on HMM: 1-116/270
Sequence Identity: 21% (25 aa)

YIKQKQIGGGQYGKVFEAKDK---QNVFQNIAIKQVNLQYVRPN--------EKEIWKQI-KGQYVVELYDCVQ-DEQN--MYFIMEKCEGGNLQKYIED
 .. |..| |..|.|.... |   .|  .  |.| .. ..  ..        | .| ||. . . .| || ..  ...   .| .|| ...|.| .|  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----SSKQANKQLTQY
      .   |.| |.
HREDKQPLTMKDLLQM
Kinase 16220.AA STE 247-276 28 0.017418 4.74 In-house 328-359 (359) Show / Hide 
Range on Protein: 247-276
Range on HMM: 328-359/359
Sequence Identity: 28% (9 aa)

QPIKDLIQRMIVYQQNQRLTIDEVLN--HPAF
.. || |..  ..  |.| | .. |.  || .
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI