Gene 18188 (Tetrahymena)
18188
Sequence
Protein domains of 18188.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 18188.AA | AGC | 148-406 | 26 | 3.8e-125 | 325.15 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 148-406 Range on HMM: 1-395/395 Sequence Identity: 26% (104 aa) FDLRFVIGRGGFGKVWRVENK------KTKQIYALKEMCKAK-VISKR--SVNSVMNE------------RQLLASLH----------HAFLIN-MVYAF |.. |||.|.||||. |. | |...||.| . |.. .. |. | .|.| |. |. .. | |... . |.| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDRQN--LYLVMDLLT---------GG-DLRFHIS---RHRRFSEEQTKFFSAC-------IIVGLEYLHQ-NGILHRD-IKPENLVFDNKGYIRITDLG || .. ||.||... || .| .|. . .||.||...|. |. |. .|||||. .|| ||| .||||...|..|.|..|| | QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG IARI--------------------------------------WKPDN--------------SSDTSG--TPGYMAPEVMCRHNHGVAVDYYA--LGIIVY . . |. .| . | || |||||. .| |.|... ||.. | LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY ECMMGRRPYVGKTRQ----------EIRDQILAKQ-VQIKKADVP----------EGWSLEAADFANRLIQRKPANRLG-LN------GPDEVKNHVWF | . |. |. |...| |. ..|. . .. .| | . .| || |. ..|... |..||| .. | .|.||| || EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | 18188.AA | Ciliate-E2-Unclassified | 148-406 | 30 | 2.2e-115 | 389.64 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 148-406
Range on HMM: 1-352/352
Sequence Identity: 30% (108 aa)
FDLRFVIGRGGFGKVWRVENKKTKQIYALKEMCKAKVISKRSVNSV---------MNERQ-------------LLASLHHAFLINMVYAFQDRQNLYLVM
. . .||.||||||.....||.||.||.|.|.|............ ||... .| .. | |...|.|.|||.||.|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
DLLTGGDLRFHIS----------------RH-RRFSEEQTK-----FFSACIIVGLEYLHQNG-ILHRDIKPENLVFDNKG---YIRITDLGIAR-----
... ||||...|. .. ..|.|.|.| |. |.|..||||||... |.||||||||..|||.| ||.|.|.||..
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
------------IWKPDNSSDTSGTPGYM----APEVMCRHNHG----VAVDYYALGIIVYECMMGRRPYVGKTRQE----------------IRDQILA
|||........|||.|| ||||....|.. ..|...||.| ||...|..|. .... . ....|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ
KQVQIKKAD---VPEGWSLEAADFANRLIQRKPANRLGLN-GPDEVKNHVWF
|..|..|.. .| .|| ||.|| |.|.|... .... . ......|| ||
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 18188.AA | Ciliate-E2 | 148-406 | 24 | 2.6e-92 | 313.0 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 148-406 Range on HMM: 1-365/365 Sequence Identity: 24% (95 aa) FDLRFVIGRGGFG-----KVWRVEN------------------KKTKQIYALKEMCKAKVISKRSVNSVM----------NERQLLASLHHAFLINMVYA ... .||.|.|| |||.| . | ...|||.| | | ..... .....| ||...| .| | ..|.|... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--DRQNLYLVMDLLTGGDLRFHIS------------------RHRR-FSEEQTK-------FFSACIIVGLEYLHQNG-ILHRDIKPENLVFDNKGYI || |..|.||||... ||||. .| .... ....... |. ||||..|||||... |.||||||||..| | FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I RITDLGIARI---------------WKPDNSSDT-------------------SGTPGYMAPEVMCRHN---------HGVAVDYYALGIIVYECMMGRR |.|.|.... |... ..|| |||||||||. . . .. ..|...||.| ||...|.. KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PYVGKTRQEIRDQILAKQVQIKKAD-------------VPEGWSLEAADFANR----LIQRKPANRLGLNGPDEVKNHVWF |. .||. ..... ... .. ||.|. |. .. ..|..| .|.. |.....|| || PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF |
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| Kinase | 18188.AA | S_TKc | 148-406 | 31 | 6.2e-89 | 302.68 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 148-406 Range on HMM: 1-231/231 Sequence Identity: 31% (86 aa) FDLRFVIGRGGFGKVWRVENKKTKQIYALKEMCKAKVISKRSVNSVMNERQLLASLHHAFLINMVYAFQDRQNLYLVMDLLTG--GDLRFHISRHRR--- ... .||.|.||||... .|||..|.|.|.. .....|.|.| . || ..... ..||| ..||.||... | |||. .| ...| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FSEEQTKFFSACIIVGLEYLHQNGILHRDIKPENLVFDNKGYIRITDLGIARIWKPDNSSDTSGTPGYMAPEVMCRHNHGV-AVDYYALGIIVYECM |.| ...|. . |. .|||.|..||.|||.||||. .|. | |.| |.||. . ||| ||||||. .| ..| ...|.|.||.. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML MGRRPYVGKTRQEIRDQILAKQVQIKKADVPEGWSLEAADFANRLIQRKPANRLGLNGPDE----VKNHVWF |. |. . |.. ..|. | || || ... |. |..|.. . .|.| || CGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 18188.AA | SGK | 148-406 | 34 | 6.3e-88 | 271.56 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 148-406 Range on HMM: 1-283/283 Sequence Identity: 34% (99 aa) FDLRFVIGRGGFGKVWRVENKKT------------------KQIYALKEMCKAKVI-------SKRSVNSVMNER-QLLASLHHAFLINMVYAFQDRQNL ||. ||| |.|||| |. |.. ...||.| |. .| | ... .| || .| . | |..| |||| . | FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YLVMDLLTGGDLRFHISRHRRFSEEQTKFFSACIIVGLEYLHQNGILHRDIKPENLVFDNKGYIRITDLGIAR--IWKPDNSSDTSGTPGYMAPEVMCRH |.||| . ||.. .|. | ..|.| . .| | |. ||||| | .|| ||||.. | .|....|| | . | . | . ||| |.||||. . YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ NHGVAVDYYALGIIVYECMMGRRPYVGKTRQEIRDQILAKQVQIKKADVPEGWSLEAADFANRLIQRKPANRLGLN-GPDEVKNHVWF |. .|| . ||.. || |.| |. . .|. |.|. . ||.. . | .| | . | |. | .||| . . |.|||..| PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPP-----QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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| Kinase | 18188.AA | Akt | 148-406 | 37 | 3.9e-82 | 262.35 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 148-406 Range on HMM: 1-264/264 Sequence Identity: 37% (100 aa) FDLRFVIGRGGFGKVWRVENKKTKQIY-ALKEMCKAKVISKRSVNSVMNERQLLASLHHAFLINMVYAFQDRQNLYLVMDLLTGGDLRFHISRHRRFSEE ||. |.|.| |||| |. |.|...| |.| | . | |. | .. || .| | |..|..|.||. ..||.||| ||.| .|..| |||||. FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED QTKFFSACIIVGLEYLHQNGILHRD-IKPENLVFDNKGYIRITDLGIAR-I-WKPDNSSDT-SGTPGYMAPEVMCRHNHGVAVDYYA-LGIIVYECMMGR ...|. | || ..|.||...| || ||||.. |..|.|..|| | .. . | . .| ||| |.|||. . |. ||| .. ||.. || | || RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR RPYVGKTRQEIRDQILAKQVQIKKADVPEGWSLEAADFANRLIQRKPANRLG--LNGPDEVKNHVWF |. . ... ..|. ..|.... . .| |. |. ..| .. | .||| |. .|.|.| || PPFYNQDHHQMFKKIKNQPVKFPDK---DWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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| Kinase | 18188.AA | Pkinase | 148-406 | 29 | 2.7e-75 | 261.23 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 148-406 Range on HMM: 1-293/293 Sequence Identity: 29% (88 aa) FDLRFVIGRGGFGKVWRVENKKTKQIYALKEMCKAKVISKRSVNSVM-NERQLLASLHHAFLINMVYAFQDRQNLYLVMDLLTGG----DLRFHIS--RH . . .||.|.||.|.. .|.| .|.|.|...| . |. .. . .| |....|.| . . . ..|.|....|.||... || || .|| || YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH RRF--SEEQTKFFSACIIVGLEYLHQNGILHRDIKPENLVFDNKGYI----RITDLGIAR---IWKPDNSSDTSGTPGYMAPEVMC-RHNHGVAVDYYAL ..| ||.. ||. |. ||||.|..||.|||.||||. .||.|.| .|.| |.|. . . .. |||.|||||| . .| .|| ... GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GIIVYECMMGRRPYVGKTRQEIRDQILAKQVQIKKADVPEGWS-----------------------LEAADFANRLIQRKPANRLGLNGPDEVKNHVWF |.|.|| . || |. |. ..... ... ..|....... |. |. || .......|. |.. ......| || GCILYEMLCGRPPFPGHC-WHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF |
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| Kinase | 18188.AA | RSK | 153-406 | 34 | 1.9e-73 | 250.34 | In-house | 3-278 (278) | Show / Hide |
Range on Protein: 153-406 Range on HMM: 3-278/278 Sequence Identity: 34% (95 aa) VIGRGGFGKVWRVENK---KTKQIYALKEMCKAKVISK-RSVNSVMNERQLLASLH-HAFLINMVYAFQDRQNLYLVMDLLTGGDLRFHISRHRR---FS | |.||.||| . . .|.|||| | |||.. . ... .| ||. |. | |... ||||. . |||.|... ||.| |...... || VLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFS EEQTKFFSACIIVGLEYLHQNGILHRDIKPENLVFDN---KGYIRITDLGIARIWKPDNSSDTS---GTPGYMAPEVMC---RHN-HGVAVDYYALGIIV |. .| | |.. .|.||| || |||.|||| ..|. | |..|| | ... ..|... | .| |||||. . . |. |.|.. ||.. EDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLM YECMMGRRPYVG---KTRQEIRDQILAKQ--VQIKKADVPEGWSLEAADFANRLIQRKPANRLG--LNGPDEVKNHVWF || .|..|. | ..|.|| ..|. .. . .. .. | || |. ... .| |..||| .. .|.|.| || YEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMP---NWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 18188.AA | AktR | 148-406 | 33 | 9.9e-70 | 237.97 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 148-406 Range on HMM: 1-268/268 Sequence Identity: 33% (92 aa) FDLRFVIGRGGFGKVWRVENK-KTKQIYALKEMCKAKVISKRSVNSVMNERQLLA-SLHHAFLINMVYAFQDRQNLYLVMDLLTGGDLRFHISRHRRFSE |.. ..|.|.|||| |. | .....||.| | | | .. . .||. .. | |.....|.||.. .|...|. ||.| .|... ..||| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE EQTKFFSACIIVGLEYLHQN-GILHRDIKPENLVFDNKGYIRITDLGIAR--IWKPDNSSDTS--GTPGYMAPEVMCR-HNHGVAVDYYALGIIVYECMM ||..|..| |. .||||||. | ||.||||.. | |...||| | .. . . .. .| ||| |||||. . |. .||..|.|| .|| .. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT GRRPYVGKTRQEIRDQILAKQ-VQIKK-ADVPEGWSLEAADFAN-RLIQRKPANRLG--LNGPDEVKNHVWF | | | .... . |. || ..... ... | .. |. . .| .. | .||| ||..|.|.| || GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYF----SSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | 18188.AA | PKA | 148-406 | 33 | 6.1e-65 | 222.07 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 148-406 Range on HMM: 1-263/263 Sequence Identity: 33% (90 aa) FDLRFVIGRGGFGKVWRVENKKTKQIYALKEMCKAKVISKRSVNSVMNERQLLASLHHAFLIN-MVYAFQDRQNLYLVMDLLTGGDLRFHISRHRRFSEE |.. ..|.| ||.| . .|.....||.| . |.... . | |.||.. | ...| |... | . |||...||.||.. ||.. .. . .|||. FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP QTKFFSA-CIIVGLEYLHQNGILHRDIKPENLVFDNKGYIRITDLGIARIWKPDNSSDTSGTPGYMAPEVMCRH-NHGVAVDYYALGIIVYECMMGRRPY ..|| | |. |||||. | .|| ||||. |..|.| ||| | | . ... ||| |.|||. .. || .|| ||||..|| . | | HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPF VGK--TRQEIRDQILAKQVQIKKADVPEGWSLEA---ADFANRLIQRKPANRLG--LNGPDEVKNHVWF . . .| . |.. ... |. . | |. ..|.|. . |.| || . .||| || YDHNRDPMQIYEKICNGKIK-----FPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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| Kinase | 18188.AA | MAST | 148-295 | 33 | 1.6e-48 | 145.94 | In-house | 1-151 (337) | Show / Hide |
Range on Protein: 148-295 Range on HMM: 1-151/337 Sequence Identity: 33% (51 aa) FDLRFVIGRGGFGKVWRVENKKTKQIYALKEMCKAKVISKRSVNSVMNERQLLASLHHAFLINMVYAFQD--RQNLYLVMDLLTGGDLRFHISRHR-RFS |. .|..|..|.|. |..|||....|.| ... | | |..|. || |. . | .| |.|| .. |..||. . ||| .... .. FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP EEQTKFFSACIIVGLEYLHQNGILHRDIKPENLVFDNKGYIRITDLGIARI |. .|. | .. .||||| || |||.||.|...| .| | .|| | . . EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKV |
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| Kinase | 18188.AA | MAST | 148-289 | 38 | 3.5e-47 | 149.94 | In-house | 1-142 (334) | Show / Hide |
Range on Protein: 148-289 Range on HMM: 1-142/334 Sequence Identity: 38% (54 aa) FDLRFVIGRGGFGKVWRVENKKTKQIYALKEMCKAKVISKRSVNSVMNERQLLASLHHAFLINMVYAFQDRQNLYLVMDLLTGGDLRFHISRHRRFSEEQ |. .|..|..|||. |..|||....|.| ..|. | | |..|. || || . | .| |.|| ...|..||. . |||. .... .| |. FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM TKFFSACIIVGLEYLHQNGILHRDIKPENLVFDNKGYIRITD .|. | .. .|||||. || |||.||.|...|..| | .|| AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTD |
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| Kinase | 18188.AA | MAST | 306-406 | 38 | 2.2e-28 | 83.26 | In-house | 230-337 (337) | Show / Hide |
Range on Protein: 306-406 Range on HMM: 230-337/337 Sequence Identity: 38% (43 aa) GTPGYMAPEVMCRHN-HGVAVDYYALGIIVYECMMGRRPYVGKTRQE-IRDQILAKQVQIKKADVPEG--------WSLEAADFANRLIQRKPANRLGLN ||| |.|||| . .| .||....|||.|| | | .| |..| | ..|. .. | ||. | || | ..| | | ||| | GTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIE---WPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN GPDEVKNHVWF | ||.|.| | GADEIKQHPFF |
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| Kinase | 18188.AA | MAST | 306-406 | 40 | 1.8e-26 | 82.06 | In-house | 226-334 (334) | Show / Hide |
Range on Protein: 306-406 Range on HMM: 226-334/334 Sequence Identity: 40% (45 aa) GTPGYMAPEVMCRHN-HGVAVDYYALGIIVYECMMGRRPYVGKTRQEIRDQILAKQVQIKK-ADVPEG--------WSLEAADFANRLIQRKPANRLGLN |||.|.|||| . || .||. ..|||.|| . | | ...|..|| ..|| . ||| | || | ..| | | ||| | GTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNC---NEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGAN -GPDEVKNHVWF | ||||.| | NGADEVKQHPFF |
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| Kinase | 18188.AA | TyrKc | 148-384 | 19 | 9.9e-14 | -0.69 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 148-384 Range on HMM: 1-280/280 Sequence Identity: 19% (55 aa) FDLRFVIGRGGFGKVWRVENKKTKQIYALKEMCKAKVISKRSVNSVMNERQLLASL--HHAFLINMVYAFQDR-------QNLYLVMDLLTGGDLRFHIS | ..|.| ||.|.. . | . | | . . . . |.| ... .| || ..... . . . |..|| . .|||. .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR RHRR-FSEEQTKFFSACIIVGLEYLHQNGILHRDIKPENLVFDNKGYIRITDLGIARIWKPD------NSSDTS----GTPG-----YMAPEVMCRHNHG .||. .. .. |. | | ||||.... |||. | .... ..|.| | .| .. | . .. |. . ||||.. . KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT VAVDYYALGIIVYE-CMMGRRPYVG-----KTRQEIRDQILAKQVQIKKAD--------VPEG--------WSLEAAD-----FANRLI . | .. |. .| . | || | .. ||.. .. . . .. |. | ...| ... TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | 18188.AA | Pkinase_Tyr | 148-272 | 22 | 3.1e-07 | 25.12 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 148-272 Range on HMM: 1-137/270 Sequence Identity: 22% (31 aa) FDLRFVIGRGGFGKVWRVENK----KTKQIYALKEMCKAKVISKRS--VNSVMNERQLLASL-HHAFLINMVYAFQ-DRQN--LYLVMDLLTGGDLRFHI . ..|.| ||.|.. . | .||. | | . | ... . |.| ... .| || ..... . ... .|.|| . .|||. . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL SRH----RRFSEEQTKFFSACIIVGLEYLHQNGILHRDI .| .... .. ... | |.|||..... |||. RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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