Gene 20643 (Tetrahymena)

20643

Species: Tetrahymena
Alias: TTHERM_00148840, 12.m00317, 3700.m00039, PreTt20643, 529, 20643
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
20643.AA Protein None 2156 None Fasta, JSON
20643.kin_dom Protein Kinase Domain None 1685 None Fasta, JSON
20643.NA RNA None 6471 None Fasta, JSON

Protein domain

Protein domains of 20643.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 20643.AA Ciliate-E2-Unclassified 1494-1755 26 2.5e-81 276.48 In-house 1-352 (352) Show / Hide 
Range on Protein: 1494-1755
Range on HMM: 1-352/352
Sequence Identity: 26% (93 aa)

SNSTKQIGQGSFCKVYKGVNKQQQLVAIKEINKQHASRLNQQMNLMIQEEIKVMKALQR-------------------HNCEHILKYIDSFEDTQNKYIV
 .  ||||||.|.|||| ..|.|.........|.. ..  .|.. .. |..  ||....                   |....|.|... |.|.|| |||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

TELCKQETLLDKLQRQNS-----------------FSENEAL-----YYFFQIKDAIYYMHYSK-IAHRDIKLPNILFGLDN---KIKLADFGFSKESL-
.|.|.. .|.. .. ...                 |.|..|.     .|| || ... |.|... | |||||. ||||  ..   .||..|||.||..  
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------QEMEYQSILGTMTTV----APEVLMNKGYTLK----ADIFSLGQILSKMLFGAYLFLMQDFIQ-------------NFQYLQECI
               ........ ||  .     |||||....|  .    .||.||| ||  |||| | |  .. .|             ..|..|...
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

DQNLNRFCIEF-----QISDKTKYLLS----QMLKVDPNKRIDILKITDLYPL
..|.. .. ..     ..|.. | ...    .|||..|||||.. .|     .
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 20643.AA Ciliate-E2 1494-1755 24 5.6e-74 252.08 In-house 1-365 (365) Show / Hide 
Range on Protein: 1494-1755
Range on HMM: 1-365/365
Sequence Identity: 24% (95 aa)

SNSTKQIGQGSFCKVYKG-VNKQQQLVAIK---------------EINKQHASRLNQQMNLMIQEEIKVMK-------------ALQRHNCEHILKYIDS
 .  |.||||.| .|||. | |.|...|||                |..    ......  .|  ||..|.              |.. |. .|.|....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--DTQNKYIVTELCKQETLLDKLQRQ-----------NSFSENEALYYFFQIKD---------------AIYYMHYSK-IAHRDIKLPNILFGLDNKI
|.  |..| |.|.|.|.. .|.| .. .           ..|.|.|..|.. || .               |. |.|  . | |||||. ||||     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLADFGFSKESLQE--------------------------------MEYQSILGTMTTVAPEVLMNKG---------YTLKADIFSLGQILSKMLFGAYL
|..|||.||.  ..                                . ...|.||   .|||.|..|.         |. |.||.||| ||  |||| . 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FLMQDFIQNFQYLQECIDQNLNRFCIE---------------FQISDKTKYLLSQ----MLKVDPNKRID-ILKITDLYPL
|           .|. ...... .| |               ...|...| |...    ||..||.|||. . .| .   .
F-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 20643.AA CAMK 1499-1746 22 1.5e-61 196.75 In-house 1-416 (425) Show / Hide 
Range on Protein: 1499-1746
Range on HMM: 1-416/425
Sequence Identity: 22% (94 aa)

QIGQGSFCKVYKGVNK-QQ------------QLVAIKEINKQHASRLN-----------------------QQMNLMIQEEIKVMKALQ----RHNCEHI
..|.|||.||.....|  .            | |||| |.|. ..  .                       ...  ... ||..|| ||    . . ..|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKYIDSFED-----------TQNK---------YIVT---ELCKQE----TLLDKLQRQNS---------------FSENEALYYFFQIKDAIYYMHYSK
.| .. .||           | .|         |.|.   |.|        |.|..... .               |.| || .|| || .|. |.|  .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHRDIKLPNILFGLD-----------------NKIKLADFGFSKESLQ------------------------EMEYQSILGTMTTVA-PEVLMN-----
|.|||.|. |||.  .                 |.||..||||...  .                           ..   ||   .| ||||       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KGYTLKADIFSLGQILSKMLFGAYLFL---MQDFIQ------NFQYLQECIDQNLNRFCIEFQ--------------ISDK--------TK
         ..|. |.|. |.| ||  || | . |     .. ..      | . | | | .   .|  ..               |||          |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

YLLSQMLKVDPNKRIDI
 |...||.|||.||. |
DLIRKMLQVDPEKRMTI
Kinase 20643.AA ULK 1494-1746 29 2.5e-60 206.73 In-house 1-320 (329) Show / Hide 
Range on Protein: 1494-1746
Range on HMM: 1-320/329
Sequence Identity: 29% (96 aa)

SNSTKQIGQGSFCKVYKGVNKQQ-----QLVAIKEINKQHASRLN-----QQMNLMIQEEIKVMKALQ---RHNC--EHILKYIDSFEDT--QNKYIVTE
 .  ...|.||| ||||| ||..     ..||.| | ||  .. |     |.|  ... |||.|| |    ||..  ..| |..| ||..   | ||..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCKQETLLDKLQ----------RQNSFSENEALYYFFQIKDAIYYMHYSKIAHRDIKLPNILFG-LDNK-----------IKLADFGFSKESLQE----M
.| . .| . ..          ... .||.||. .| ||  .  ..|  .| |||||. |||    . |           .|.|||||.|    .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

EYQSIL------GTMTTVAPEVLM----NKGYT-LKADIFSLGQILSKMLFGAYLFLMQDFIQNF-QYLQECIDQ------NLNRFCIEFQ-------IS
 ... .      ||  . ||..|.    .| |.  |.||.||| |.  ||.| . |  . | . . |..|. |..      . . . ..|.       ||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

DKTKYLLSQMLKVDPNKRIDI
...| |...||..|...||..
PECKDLIRRMLQYDEKDRISW
Kinase 20643.AA S_TKc 1494-1755 27 3.8e-60 207.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 1494-1755
Range on HMM: 1-231/231
Sequence Identity: 27% (78 aa)

SNSTKQIGQGSFCKVYKGVNKQ-QQLVAIKEINKQHASRLNQQMNLMIQEEIKVMKALQRHNCEHILKYIDSFEDTQNKYIVTELCKQ--ETLLDKLQRQ
    ..||.|.| ||||...|  ...||||.|.             .|. ||...|     ....| |..|.|.| .. |.|.|.| .   .|.| ....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR

NS------FSENEALYYFFQIKDAIYYMHYSKIAHRDIKLPNILFGLDNKIKLADFGFSKESLQEMEYQSILGTMTTVAPEVLMNKGYTL-KADIFSLGQ
..      |.| .| .|. || .|. |.|  .| |||.|  |||.     ||..|||....        .. ||   .|||||   ||.  |.|. |.| 
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

ILSKMLFGAYLFLMQDFIQNFQYLQECIDQNLNRFCIEFQISDKTKYLLSQMLKVDPNKRIDILKITD-------LYPL
||  || |  .|      | .. .. .              |.  | .....|..||.||. . ..            .
ILYEMLCGYPPFP-----QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 20643.AA ULK 1494-1746 29 4.3e-57 195.99 In-house 1-315 (324) Show / Hide 
Range on Protein: 1494-1746
Range on HMM: 1-315/324
Sequence Identity: 29% (95 aa)

SNSTKQIGQGSFC-KVYKGVNKQQ----QLVAIKEIN--KQHASRLN---QQMNLMIQEEIKVMKALQRHNCEH--ILKYIDSFEDT--QNKYIVTELCK
 .  ...|.|||  ||||| ||..    |.||.| |.  |.  . ..   |.|  ... ||..|| | . ....  | |..| ||..   | ||..|.| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

QETLLDKLQ---------RQNSFSENEALYYFFQIKDAIYYMHYSKIAHRDIKLPNILFGLDNK--------------IKLADFGFSKE----SLQEMEY
. .| . ..         ... .||.||. .| ||  .  ..|  .| |||||. |||  . |.              .|.|||||.|     ..... .
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNIL--IHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMC

QSIL------GTMTTVAPEVLM----NKGYT-LKADIFSLGQILSKMLFGAYLFLMQDFIQNFQYLQECIDQ------NLNRFCIEFQ-------ISDKT
|...      ||  . ||..|.    .| |.  |.||.||| |.  ||.| | |  . | . ..| |. |..        .   |.|.       ||...
QTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPEC

KYLLSQMLKVDPNKRIDI
| |...||..|...||..
KDLIRRMLQYDEKDRISW
Kinase 20643.AA Pkinase 1494-1749 28 1.1e-53 189.43 Pfam 1-287 (293) Show / Hide 
Range on Protein: 1494-1749
Range on HMM: 1-287/293
Sequence Identity: 28% (83 aa)

SNSTKQIGQGSFCKVYKGVNKQQQL-VAIKEINKQHASRLNQQMNLMIQEEIKVMKALQRHNCEHILKYIDSFEDTQNKYIVTELCKQE----TLLDKLQ
    ..||.||| .|||...|  .  ||.|.|.|.|..   .| .. .  ||..|| |.   ...|....|.||| .. |.|.|.|        | | ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLN---HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

--RQNSF--SENEALYYFFQIKDAIYYMHYSKIAHRDIKLPNILFGLDNKI----KLADFGFSK---ESLQEMEYQSILGTMTTVAPEVLM-NKGYTLKA
  |...|  ||.|.  |. ||  ...|.|  .| |||.|. |||.  .. |    |..|||..|   .  ..  .... ||   .||||.. ...|. |.
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKV

DIFSLGQILSKMLFGAYLFLMQ----DFIQNFQYLQECIDQNLNRFCIEF------------------QISDKTKYLLSQMLKVDPNKRIDILKI
|..|.| ||  ||.|  .|  .    . .   | ...  .  | . . .                    .|.  | ... .|..||.||. .  |
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI
Kinase 20643.AA CAMKL 1498-1749 28 1.8e-49 155.93 In-house 5-291 (297) Show / Hide 
Range on Protein: 1498-1749
Range on HMM: 5-291/297
Sequence Identity: 28% (83 aa)

KQIGQGSFCKVYKGVN-KQ-QQLVAIKEINKQHAS-RLNQQMNLM---------IQEEIKVMKALQ--RHNCEHILKYIDSFEDTQN------KYIVTEL
|..|.||| ||  ... .  .. |||| |.|. .. . . ..|           |. ||. || |.  .|  ..| |  . .|. ..       |.|.|.
KTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKH--PNIIKLYEVIETPEHDIETKKIYLVMEY

CKQET--LLDKLQRQ----NSFSENEALYYFFQIKDAIYYMHYSKIAHRDIKLPNILFGLDN--KIKLADFGFSKESL-Q----EMEYQSILGTMTTVAP
|      |.|.....     ...|.||  || || .|..|.|  .|.|||||. |||.  ..  .||..||||| .   .    .       |.    ||
CSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAP

EVLMN--KGYT-LKADIFSLGQILSKMLFGAYLFLMQDF---IQNFQYLQECIDQNLNRFC-IEFQISDKTKYLLSQMLKVDPNKRIDILKI
|..    | |   |.|| |.| ||  |..|.. |  ..    ... . . . ..  .  .  | ...|   . |...||.|.|.||. |  |
EIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI
Kinase 20643.AA CAMK1 1497-1682 31 4.3e-41 117.17 In-house 211-410 (276) Show / Hide 
Range on Protein: 1497-1682
Range on HMM: 211-410/276
Sequence Identity: 31% (64 aa)

TKQIGQGSFCKVYKGVNKQ----QQLVAIKEIN-KQHASRLNQ-QMNLMIQEEIKVMKALQRHNCEHILKYIDSFEDTQNKYIVTELCKQETLLDKLQRQ
.|.|| |.| .||....|.    .. .||| |. |.. .  .. .   ... || .|| . . ....| | .. .|..   |.|.||..   |.|.    
GKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIVEK

NSFSENEALYYFFQIKDAIYYMHYSKIAHRDIKLPNILF---GLDNKIK--LADFGFSKESLQEM-EYQSILGTMTTVAPEVLMN---KGYTLKADIFSL
 ...|..|     || .|..|||.  |.|||.|  |.|.     | |||  .|||| ||   ..    .   ||   |||||| .   |.|  . |..| 
GNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSI

G
|
G
Kinase 20643.AA STE 1495-1743 21 1.9e-39 136.94 In-house 1-345 (359) Show / Hide 
Range on Protein: 1495-1743
Range on HMM: 1-345/359
Sequence Identity: 21% (76 aa)

NST-KQIGQGSFCKVYKGVNK----------------QQQLVAIKEINKQHASRLNQQ-------------MNLMIQEEIKVMKALQRHNCEHILKYIDS
    ..||.|.| .|||..|.                .....|||..|... .  . .                 |..|||.|| ..   ...| ||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGC

FEDT-------QNKYIVTELCKQETLLDKLQ------RQNS--------FSENEALYYFFQIKDA-IYYMHYSKIAHRDIKLPNILFGLDNKIKLADFGF
...        .. .|. |..   .| | ..      ....        |.|..  |. .||  .  || |  .| |||||  |||.     .||.|||.
YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGV

SKESLQEM-----------------EYQSILGTMTTVAPEVLMN------KGYTLKADIFSLGQILSKMLFGAYLF-LMQDFIQNFQYLQE--------C
..   ..|                 . ... ||    ||||...      |||. |.|| |||  .  |. | . .  |...   |. ...         
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

IDQNLNRFCIEFQ---------------------ISDKTKYLLSQMLKVDPNKR
. . .|  .  ..                      |.. |  ... |. |||||
L-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKR
Kinase 20643.AA CAMK-Unique 1494-1691 21 1.3e-37 121.6 In-house 1-289 (363) Show / Hide 
Range on Protein: 1494-1691
Range on HMM: 1-289/363
Sequence Identity: 21% (64 aa)

SNSTKQIGQGSFCKVYKGVN-KQQQLVAIKEINKQHASRLNQQM---------------NLMIQEEIKVMKALQRHNCEHILKYIDS----FEDTQ----
    . ||.|.|..||.. . .   . |.| ..|| ...  |                 .    .|. ..| .   . ..|.|  |     |.| .    
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMV---DHPNIIKLYDWNNPIFCDRKYPLC

-----------NKYIVTELCKQETLLDKLQR--------------------QNSFSE--NEALYYFFQIKDAIYYMHYSKIAHRDIKLPNILFGLD----
           . |||.|.|   .|.|..|.                    | .|||  .... .....  |. |||  .| |||.|| ||..       
DLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDN

------------NKIKLADFGFSKESLQEMEYQ---SILGTMTTVAP--------------EVLMNKGYTLKA----DIFSLGQILSKMLFG
            ..|||.||| ...  .  ..    .. ||   .||              ||... .|  .     || ||| |.  ||.|
NHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCG
Kinase 20643.AA Ciliate-E2a 1497-1695 31 4.2e-37 106.78 In-house 4-216 (275) Show / Hide 
Range on Protein: 1497-1695
Range on HMM: 4-216/275
Sequence Identity: 31% (68 aa)

TKQIGQGSFCKVYKGVNKQQQLV-AIKEINKQHASRLNQQMNLMIQEEIKVMKALQRHNCEHILKYIDSFEDTQNKYIVTELCKQETLLDKLQRQNSFSE
.|.||.|.| .||.   ||.    |.| ..|  . . . . .  .. ||. |. |   .  .|.| .. .|| .| |.|.|.|.  .|.||.. . .| |
IKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK--KMYQQKKGKEYFMNEINIMRQL---DHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFE

N--EALYYFFQIK-DAIYYMHYSKIAHRDIKLPNILFG---LDN----KIKLADFGFSKES--LQEMEYQSILGTMTTVAPEVLMNKG------YTLKAD
.  |.  .  |.  ... |||  .| |||.|. ||||     ..    .||..|||...     ..    .. ||   |||||| ||       |. | |
EIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCD

IFSLGQILSKMLFGAYLF
..|.| |.  .|.|  .|
MWSCGVIFYILLCGKPPF
Kinase 20643.AA Pkinase_Tyr 1498-1682 26 8.5e-14 47.35 Pfam 5-201 (270) Show / Hide 
Range on Protein: 1498-1682
Range on HMM: 5-201/270
Sequence Identity: 26% (53 aa)

KQIGQGSFCKVYKGVNK-----QQQLVAIKEINKQHASRL-NQQMNLMIQEEIKVMKAL-QRHNCEHILKYIDSFE-DTQN--KYIVTELCKQETLLDKL
|..|.|.| .||||. |     ... ||.| . |..|.   |  .  .  .|.|.|| | .   ...|....     . .    |||.|...   ||| |
KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQN--CREDFMREAKIMKQLGH---HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QR----QNSFSENEALYYFFQIKDAIYYMHYSKIAHRDIKLPNILFGLDNKIKLADFGFSKESLQEMEY-QSILGTMTTV---APEVLMNKGYTLKADIF
..    .....  . | . .|| ..  | .  .. |||.   |.| . .|..| .||| ..    . .| ..  |..  .   |||..... .| | |. 
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLG
| |
SFG
Kinase 20643.AA TyrKc 1494-1753 19 2e-13 -5.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 1494-1753
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

SNSTKQIGQGSFCKVYKGVNKQQQLVAIKEINKQHASRLNQQMNLMIQEEIKVMKAL-QRHNCEHILKYIDSFEDT-------QNKYIVTELCKQETLLD
    |..| | |..||||. |  . ||.| ... .          .. .|...|. |  .|  ..|.. .    .        .  .||.|...   |.|
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--------REDFMREARIMCKLGGHH--PNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

KLQRQNS-FSENEALYYFFQIKDAIYYMHYSKIAHRDIKLPNILFGLDNKIKLADFGFSKESLQE------MEYQSIL---GTM--TTV---APEVLMNK
 |..    ..  . |.. .|| .   | |  .. |||.   |.| | .. .| .||| |..   .       .| .     |.     .   |||... .
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

GYTLKAD----------IFSLGQILS-------KMLFGAYLFLMQD-FIQNFQY-LQECIDQNLNRFCIEFQISDKTKYLLSQMLKVDPNKRIDILKITD
 .| | |          ||..||          .  . .. ...|       .. . . .      |      .|.   . .|  . ||..|     | .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS-----F---VCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

LY
. 
CF
Kinase 20643.AA Ciliate-E2a 1723-1746 41 3e-06 14.47 In-house 243-266 (275) Show / Hide 
Range on Protein: 1723-1746
Range on HMM: 243-266/275
Sequence Identity: 41% (10 aa)

QISDKTKYLLSQMLKVDPNKRIDI
..|. .| |...||..||.|||..
KCSKECKDLMKKMLEKDPKKRITA
Kinase 20643.AA CAMK1 1724-1746 45 5.6e-05 10.35 In-house 244-267 (276) Show / Hide 
Range on Protein: 1724-1746
Range on HMM: 244-267/276
Sequence Identity: 45% (11 aa)

ISDK-TKYLLSQMLKVDPNKRIDI
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ISDQEAKDFIKHMLEVDPKKRYTC
Kinase 20643.AA CAMK-Unique 1724-1746 30 0.026661 3.17 In-house 332-354 (363) Show / Hide 
Range on Protein: 1724-1746
Range on HMM: 332-354/363
Sequence Identity: 30% (7 aa)

ISDKTKYLLSQMLKVDPNKRIDI
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ISQEAKDFVKCCMTVDPDHRWSA