28547

Species: Tetrahymena
Alias: PreTt28547, TTHERM_00161570, 28547, 13.m00506, 3829.m01368, 124
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2

Sequence

Name Sequence Type Origin Length Description Download
28547.AA Protein None 769 None Fasta, JSON
28547.kin_dom Protein Kinase Domain None 263 None Fasta, JSON
28547.NA RNA None 2310 None Fasta, JSON

Protein domain

Protein domains of 28547.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 28547.AA Ciliate-E2-Unclassified 104-366 25 2.5e-92 313.03 In-house 1-352 (352) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-352/352
Sequence Identity: 25% (89 aa)

YKILQKVGKGGYGSVYEARHRITKERI-----AIKMINGS-SIRSAKDIEMMFKEIGLLKN----------------LNHKNIIKVLNCYTLKSEMKLAI
|||... |.||.|.||...|. .|  .     ..|... .  .   || |.|.... . ..                |||.....|  .|. ... .. |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VFEYLEGGDLREYLDKQPG---------------QCVDEEVAR-----KIFLQLFNAIQYCHREK-IIHRDLKLENIMFTSKNY-DVIKVVDFGISAQQS
| ||.|||||..|. |...               ....|. |.     ..| |. ....|.|... |||||.|.|||.|.....   ||. ||||| .. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

LI----------------NIDYTQAGSARYF----APEVLSSKAPAHP---SIDVWAMGCILFWVIVGKSPFPQSTKEE----------------VFNNI
                  .. .|..|. .|     ||||| .. . |.   ..|.|..|.||.. . |. ||.. ..|.                ...||
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

LKGNYSIPVEAK----QRMTKSVQDLIT----KMLQVDVNSRITMNEIAQHQWL
...|...| . .    ..  ....|.|.    |||... |.|||...| .|.|.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 28547.AA CAMKL-Unclassified 104-366 36 7.4e-91 308.16 In-house 1-290 (290) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-290/290
Sequence Identity: 36% (107 aa)

YKILQKVGKGGYGSVYEARHRITKERIAIKMINGSSIRSAKDIEMMFKEIGLLKNLNHKNIIKVLNCYTLKSEMKLAIVFEYLEGGDLREYLDKQPGQCV
| |.| .| ||.| |  | |..|.|..|||... . .  | ||.| | |   || ||||||.|. ||||| |.||     |||.||.| .. .|.     
YNIVQVIGEGGFGQVQLAEHKQTQEKFAIKFVKTMNHGCAMDIDMVFREAEILKSLNHKNIVKIKNCYTL-SDMKVVMIMEYLQGGELLDWCRKN--GHF

DEEVAR-------KIFLQLFNAIQYCHREKIIHRDLKLENIMFT-SKNYDVIKVVDFGISAQQSL-INIDYTQAGSARYFAPEVLSSKAPA-HPSIDVWA
 |. ||       ..| |   |.|||| ..||||||||||.    .   .|||..||||    .  .|.    .|| || |||..  .     .|||.||
NENNARRQPWEIQQYFQQIVDAMQYCHKNCIIHRDLKLENVLLRQQDSSPVIKIFDFGIAGVANVNQNVFNINGGSLRYMAPEMKNQQVKQIQYSIDIWA

MGCILFWVIVGKSPFPQ---------------STKEEVFNNILKGNYSIPVEAKQRMTKSVQD-----LITKMLQVDVNSRITMNEIAQHQWL
|| .|.  ||.  ||                  .  ..   | .| |..| . .   .. . |     ||.. .||.   |.|  .|.|| |.
MGVMLYMCIVQFFPFNGNGNNGKNNNSDGNENDNNNNIMFKITRGPYEFPEQINKPLPDECKDQRLISLIENIFQVNPKNRFTTHQIMQHPWM

Kinase 28547.AA Ciliate-E2 104-366 23 1.6e-88 300.4 In-house 1-365 (365) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-365/365
Sequence Identity: 23% (89 aa)

YKILQKVGKGGYGSVYEARHRITKER-----------------------IAIKMINGSSIRSAKDIEMMFKEIG----------LLKNLNHKNIIKVLNC
||...| |.|..||||..... ....                       .|.|... . |.. | .. ...||           .|..|||.||||   |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YTLKSEMKLAIVFEYLEGGDLREYLDKQPGQC---------VDEEVARKIFLQLFN---------------AIQYCHREK-IIHRDLKLENIMFTSKNYD
.  |.. .. .|.||..||||..|. ... ..          .|. ...|. |...               |..|.| .. |||||.|.|||.|      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

VIKVVDFGISAQQSLINIDYT--------------------------------QAGSARYFAPEVLSSKAP--------AHPSIDVWAMGCILFWVIVGK
 ||..|||.| ...  |...|                                ..|.. | |||.|..|             ..|.|..|.||.. . ||
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

SPFPQSTKEEVFNNILKGNYSIPVE--------------AKQRMTKSVQDLITK----MLQVDVNSRIT-MNEIAQHQWL
 ||        ...|.......| .               ..  .....||| |    |||.| . ||| ...| .|.|.
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 28547.AA S_TKc 104-366 33 3e-88 300.4 SMART 1-231 (231) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-231/231
Sequence Identity: 33% (92 aa)

YKILQKVGKGGYGSVYEARHRITKERIAIKMINGSSIRSAKDIEMMFKEIGLLKNLNHKNIIKVLNCYTLKSEMKLAIVFEYLEG--GDLREYLDKQPG-
|.||.|.|||..|.|| .||. |... |||.|.          |.. .|| .||. .|.||.| . ..      .| .|.||..|  |||..|..|... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

---QCVDEEVARKIFLQLFNAIQYCHREKIIHRDLKLENIMFTSKNYDVIKVVDFGISAQQSLINIDYTQAGSARYFAPEVLSSKAPAHP-SIDVWAMGC
   .  .| .||... |...|..|||. .||||||| |||....    .||. |||...|       .|. |.  | |||||    .  . ..|.|. ||
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGC

ILFWVIVGKSPFPQSTKEEVFNNILKGNYSIPVEAKQRMTKSVQDLITKMLQVDVNSRITMNEIAQ-------HQWL
||.  ..|. |||  . ...|..|.              .... |.| |.||.| . |.|  |. |       |.|.
ILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 28547.AA CAMK 109-366 21 1.2e-87 282.44 In-house 1-425 (425) Show / Hide
Range on Protein: 109-366
Range on HMM: 1-425/425
Sequence Identity: 21% (93 aa)

KVGKGGYGSVYEARHRITK------------ERIAIKMINGSSIRS-------------------------AKDIEMMFKEIGLLKN-------LNHKNI
. |.|..| |....|. |.            .. |||.|. . ...                         .|| .....|| ..|.       |.|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKVLNCYTLKS-----------------EMKLAIVF---EYLEGG----DLREYLDKQPG-------------QCVDEEVARKIFLQLFNAIQYCHREKI
|| .  |  ..                 .... .|.   || .||    || .|. ....              ...|. ||..| |.  |..|||  .|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKLENIMFTSKNYD---------------VIKVVDFGISAQQSLINIDY------------------------TQAGSARYFA-PEVLSS------
.|||||.|||.....| |                ||..||| ...    . ..                        |. |.  | | ||||..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KAPAHPSIDVWAMGCILFWVIVGKSPFPQS-------------TKEEVFNNILKGNYSIPVEA------------KQRMTKS--------VQD
       | .  |..|.|..|.||.   .|..||  .             . .| | .|.||.|. | .               . ...        ..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LITKMLQVDVNSRITMNEIAQHQWL
|| |||||| . |.|  .. .|.|.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 28547.AA CAMKL 104-366 30 4.4e-86 274.68 In-house 1-297 (297) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-297/297
Sequence Identity: 30% (91 aa)

YKILQKVGKGGYGSVYEARH-RITKERIAIKMINGSSIRSAKDIEMM------------FKEIGLLKNLN---HKNIIKVLNCYTLKSE----MKLAIVF
|.|..  |||..| |  |.| |.|.|. |||.|. . |.    ....            ..|| ..| ||   |.|||| . ... ..     .|. .| 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYLEGGD--LREYLDKQPGQC--VDEEVARKIFLQLFNAIQYCHREKIIHRDLKLENIMFTSKNYDVIKVVDFGISAQQS-L-INID---YTQAGSARYF
|| .||.  | .|..|...     .|. ||..| |.  |..|||. .|.|||.|.|||......  .||..||| |...    .. .    |. ||  | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLSS-KAPAH-PSIDVWAMGCILFWVIVGKSPFPQST---------KEEVFNNILKGNYSIPVEAKQRMTKSVQDLITKMLQVDVNSRITMNEIAQH
|||.... . | . | .|.|..| ||.  ..|. || . |         ...  .... ... |..    ..  ...||| |||||. . |.|. .| .|
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWY----HVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

QWL
 |.
PWM

Kinase 28547.AA Pkinase 104-366 28 1.1e-82 285.78 Pfam 1-293 (293) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

YKILQKVGKGGYGSVYEARHRITKERIAIKMINGSSIRSAKDIEMMF-KEIGLLKNLNHKNIIKVLNCYTLKSEMKLAIVFEYLEGG----DLREYLDKQ
|.|..|.|.|..|.||...|. | .. |.| |. ....| ||..     || ..|.|||.||.. . ...   . .. .|.||.|||    || .|.  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

PGQCV--DEEVARKIFLQLFNAIQYCHREKIIHRDLKLENIMFTSKNYDV---IKVVDFGISAQ--QSLINIDYTQAGSARYFAPEVLSSKAPAHPSIDV
 . |.  .|........|.. ...|||...|||||||.|||..  .|...   .|. |||...|         .| .|. .| ||||. .  .  |..|.
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WAMGCILFWVIVGKSPFPQS------TKEEVFNNILKGNYSIPVEAKQRMT-----------------KSVQDLITKMLQVDVNSRITMNEIAQHQWL
|..||||. .. |. |||..      .. .....|... .. . . . ..                  .. .|.|...|..| ..|.|  .| || |.
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 28547.AA MARK 104-366 33 2.7e-71 232.32 In-house 1-262 (262) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-262/262
Sequence Identity: 33% (89 aa)

YKILQKVGKGGYGSVYEARHRITKERIAIKMINGSSIRSAKDIEMMFKEIGLLKNLNHKNIIKVLNCYTLK--SEMK-LAIVFEYLEGGDLREYLDKQPG
||.|.  |.|.|. |. |.|. |... |||...  ..   . ... . || ..| |.|.|||| .  ..     | . . .. || .||.|..|. ..|.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLF--HVIEQDTEQHQIYLIMEYASGGELYDYIKAHPN

QCVDEEVARKIFLQLFNAIQYCHREKIIHRDLKLENIMFTSKNYDVIKVVDFGISAQQSLINIDYTQAGSARYFAPEVLSSKAPAHPSIDVWAMGCILFW
 .  || ||.|| |.  |..|||.  |.|||.|.|||.  ...   ||  ||| |..    .   |  |.  | |||....|    | .|.|..| .|. 
GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

VIVGKSPFPQST--KEEVFNNILKGNYSIPVEAKQRMTKSVQDLITKMLQVDVNSRITMNEIAQHQWL
 ..|. ||  .|   .| . .||.|.|.||      . |. ..|| ..|.|. . |.|. || .| |.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 28547.AA Ciliate-E2a 104-366 32 5.6e-71 208.18 In-house 1-275 (275) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-275/275
Sequence Identity: 32% (89 aa)

YKILQKVGKGGYGSVYEARHRITKERIAIKMINGSSIRSAKDIEMMFKEIGLLKNLNHKNIIKVLNCYTLKSEMKLAIVFEYLEGGDLREYLDKQPGQCV
||.. | ||| .|||| |.|..|... |.| ..     . |. | ...|| ....|.|.||||    |  ..|  . .|.||.|||.| ... ..  .  
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVY--EDENNYYLVMEYCEGGELYDKIKQCKRFFE

DEEVARKIFLQLF-NAIQYCHREKIIHRDLKLENIMFT--SKN-Y--DVIKVVDFGISAQQ--SLINIDYTQAGSARYFAPEVLSSKAP-AHP----SID
 ......|  ||.  ...|.|  .|.|||||.|||.|.  ||| .    ||..||| . ..     .  ... |.. | ||||| .|    |.    . |
EIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCD

VWAMGCILFWVIVGKSPFPQSTKEEVFNNILKGNYSIPVEA-KQRMTKSVQDLITKMLQVDVNSRITMNEIAQHQWL
.|  |.|..  ..||.||.. | .|.. .. | ...       .  .|. .||. |||..| . ||| ... .|.| 
MWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF

Kinase 28547.AA AMPK 104-366 34 4e-66 195.31 In-house 1-254 (254) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-254/254
Sequence Identity: 34% (92 aa)

YKILQKVGKGGYGSVYEARHRITKERIAIKMINGSSIRSAKDIEMMFKEIGLLKNLNHKNIIKVLNCYTL--KSEMKLAIVFEYLEGGDLREYLDKQPGQ
| | .. |.| .| |  . | .|.|  ||| .|   |.. .. |   .|| .|| ..| .||.    |    ...  . .| ||  ||.| .|  |   .
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQL---YEVIIETPTDIFMVMEYVSGGELFDYIVKH--G

CVDEEVARKIFLQLFNAIQYCHREKIIHRDLKLENIMFTSKNYDVIKVVDFGISAQQSLINIDYTQAGSARYFAPEVLSSKAPAHPSIDVWAMGCILFWV
 ..|. |.. | |  ... |||| .| |||||.||. .  .|.  ||.|||| |   .  .  .|  ||  | |||. |.|  . | .|.|  | ||.  
RLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLD-HNKN-IKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAM

IVGKSPFPQSTKEEVFNNILKGNYSIPVEAKQRMTKSVQDLITKMLQVDVNSRITMNEIAQHQWL
. |. ||  .   . . .|..| |.||    . ......||| .||||| . ||| ..| .|.|.
LCGYLPFDDENTPTLYKKIKNGEYYIP----KFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 28547.AA CDPK 104-366 33 1.1e-65 200.52 In-house 1-271 (271) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-271/271
Sequence Identity: 33% (94 aa)

YKILQKVGKGGYGSVYEARHR-ITKERI-AIKMINGSSIRSAKDIEMMFKEIGLLKNLNHKNIIKVLNCYTLKSEMKLAIVFE--YLEGGDLREYLDKQP
|||  . |||..|.|. . |. .|...  |.|.|. |... .......|.|| .||.| | ||||.   |    |.   ||.|  |..||.| .|   . 
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFY--QDEKNYYIVMETEYCTGGELFDYIIEK-

GQCVDEEVARKIFLQLFNAIQYCHREKIIHRDLKLENIMFTSKNYD-----VIKVVDFGISAQQSLI-----NIDYTQAGSARYFAPEVLSSKAPAHPSI
  . .|  |..|. |...|..|||  .|.||||| |||.|.||. |      |||.|.|.| ..        .  ....|   | |||||  |     . 
-GHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK--YNEKC

DVWAMGCILFWVIVGKSPFPQSTKEEVFNNILKGNYSIPVEAKQRMTKSVQDLITKMLQVDVNSRITMNEIAQHQWL
|.|  | ||.  ..|  ||   . .|..... ||.||  ..  .  ... .||| |||..| . |.. ... ||.| 
DIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF

Kinase 28547.AA QIK 104-366 33 4.1e-59 202.69 In-house 1-272 (272) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-272/272
Sequence Identity: 33% (94 aa)

YKILQKVGKGGYGSVYEARHRITKERIAIKMINGSSIRSAKDIEMMFKEIGLLKNLNHKNIIKVLNCYTLKSEMKLAIVFEYLEGGDLREYLDKQPGQ--
| | . .||| .. |  |||||||...||| |  | .  ..... .. |. ..| |.| .||| ..   . ..  . || || ..|.. .|| |. |.  
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQV--METDDMMYIVTEYCSNGEMFDYLCKH-GRKG

-----------------CVDEEVARKIFLQLFNAIQYCHREKIIHRDLKLENIMFTSKNYDVIKVVDFGISAQQSLINIDYTQAGSARYFAPEVLSSKAP
                  . |..||..| |.  |..|||. .|.||||| |||..  .| . ||..||| |  .       |  ||  | |||..  |  
VKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILL-DNNMN-IKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEY

AHPSIDVWAMGCILFWVIVGKSPFPQSTKEEVFNNILKGNYSIPVEAKQRMTKSVQDLITKMLQVDVNSRITMNEIAQHQWL
  | .|.| || .|.  . |. ||. .| ..  . .| | . ||      | .  ..|| .|| || . |.|.. | ||.|.
DGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPF----FMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 28547.AA Pkinase_Tyr 104-255 28 2.3e-18 62.84 Pfam 1-158 (270) Show / Hide
Range on Protein: 104-255
Range on HMM: 1-158/270
Sequence Identity: 28% (46 aa)

YKILQKVGKGGYGSVYEARHR----ITKERIAIKMINGSSIRSAKD--IEMMFKEIGLLKNL-NHKNIIKVLNCYTLKSEM-KLAIVFEYLEGGDLREYL
 ....| |.| .|.||... .     ||   |.||..     . ..  .|....|. ..|.| .|.||.. . . | ..|  .. ||.|| ..|||..||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

DKQ--PGQCVDEEVARKIFLQLFNAIQYCHREKIIHRDLKLENIMFTSKNYDVIKVVDFGIS
 |.  ..| .. .   .. .|  .. .| .. ..|||||   |.. |. |  |.|. ||| .
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-NN-VVKICDFGLA

Kinase 28547.AA TyrKc 104-366 21 2.9e-17 56.51 SMART 1-280 (280) Show / Hide
Range on Protein: 104-366
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

YKILQKVGKGGYGSVYEARHRITKERIAIKMINGSSIRSAKDIEMMFKEIGLLKNL--NHKNIIKVLNCYTLKSE-----MKLAIVFEYLEGGDLREYLD
 . ..| | | .| ||... .   .  |.||.. ..      .|.. .|. ....|  .|.||.. . . | ...       | ||.|| ..|||..|| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KQPGQCVDEEVARKIFLQLFNAIQYCHREKIIHRDLKLENIMFTSKNYDVIKVVDFGISAQQSLI------NIDYTQAG--SAR------YFAPEVLSSK
|  .. .  .   .. .|  .  .| |. ..|||||   |.. ....  ..|. ||| |               |....  ...        |||..  .
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

APAHPSIDVWAMGCILFWVI-VGKSPFPQ-----STKEEVFNNILKGNYSIPVEAKQ-----RMTKSVQDLITKMLQVDVNSRITMNEIAQHQWL
   . | |||. |  .. .   |..| |       . .||.... .|..  . .        .... . .....  . | ..| |..||  |. .
KFTTKS-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF