Gene 4069 (Tetrahymena)

4069

Species: Tetrahymena
Alias: PreTt04069, 3675.m00013, 694, 4069, 80.m00115, TTHERM_00584610
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
4069.AA Protein None 401 None Fasta, JSON
4069.kin_dom Protein Kinase Domain None 233 None Fasta, JSON
4069.NA RNA None 1206 None Fasta, JSON

Protein domain

Protein domains of 4069.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 4069.AA AGC 141-273 33 3.3e-91 235.36 In-house 181-395 (395) Show / Hide 
Range on Protein: 141-273
Range on HMM: 181-395/395
Sequence Identity: 33% (73 aa)

LKPENVLIDQEGYIKLTDFGLSKILQNDN--------------------------------------------------EVATSVAG--TPEYLAPEILS
|||||.|.|..|.||||||||.|.. ||.                                                  . ...  |  ||||.||||| 
LKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-

EKGHGKASDWWT--LGNIIYEMVTGLPPFYDPN----------REKLFGNIL------TQPVKFD----------PRIQGNLKDLLSGLLQKDPNKRLGS
   .||| |||.  || ..|||.||.||||. |          ....| .|.      ...|||.          . .  ..|||...||.|||.||||.
---YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGC

KY------GALEIINHPWF
.       || || |||||
GGNDFGDKGAEEIKNHPWF
Kinase 4069.AA Akt 141-273 53 2e-85 273.06 In-house 127-264 (264) Show / Hide 
Range on Protein: 141-273
Range on HMM: 127-264/264
Sequence Identity: 53% (74 aa)

LKPENVLIDQEGYIKLTDFGLSK-ILQNDNEVATSVAGTPEYLAPEILSEKGHGKASDWWT-LGNIIYEMVTGLPPFYDPNREKLFGNILTQPVKFD--P
|||||.|.|..|.|.||||||.| ..  |....... |||||||||||. .||.||.|||. || ..||| .|.||||. .....| .|..|||||   .
LKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKD

RIQGNLKDLLSGLLQKDPNKRLGSKYG-ALEIINHPWF
.|. . |||.||||.|||.||||.... | || .||||
WISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 4069.AA Ciliate-E2 41-273 25 1.8e-77 263.7 In-house 1-365 (365) Show / Hide 
Range on Protein: 41-273
Range on HMM: 1-365/365
Sequence Identity: 25% (96 aa)

FNLLTIIGQGNYA-----KVSLVRK------------------KDDGQIYALKTLKRKHIKHQVQMNHIL----------TERNILKVVDSQYIVRCKYA
.... .|||||..     || .|.|                  |....|||.|..| . |... |..||.           |.|||. ... .|......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DKKRLFFALEFCQGGELFTLIK----------------------------TKGF-----------------LNENP------LKPENVLIDQEGYI
||  |.. ... .|.||||.|| .||                            ..||                 | ..       .||||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLSKILQNDNE-------------------------------VATSVAGTPEYLAPEILS---------EKGHGKASDWWTLGNIIYEMVTGLPP
|..||||||....||.                               .. ...|||.|.|||||.         .||.....|.| || |.|||..| ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYDPNREKLFGNILTQPVKFD------------------PRIQGNLKDLLSG----LLQKDPNKRLGSKYGALEIINHPWF
|        . .|. ....|.                    .  . |||..     .|||||.||..   |. .|.|||||
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT---GWEQILNHPWF
Kinase 4069.AA SGK 141-273 50 2e-71 219.71 In-house 151-283 (283) Show / Hide 
Range on Protein: 141-273
Range on HMM: 151-283/283
Sequence Identity: 50% (67 aa)

LKPENVLIDQEGYIKLTDFGLSKILQNDNEVATSVAGTPEYLAPEILSEKGHGKASDWWTLGNIIYEMVTGLPPFYDPNREKLFGNILTQPVKFDPRIQG
|||||.| | .|...||||||.|    .|.  .. .|||||||||.|  ..|... ||| || . ||| .||||||. |.. .. ||. || .. | .. 
LKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSN

NLKDLLSGLLQKDPNKRLGSKYGALEIINHPWF
  .||. ||||||| ||||.| ...|| |||.|
DAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 4069.AA S_TKc 41-273 33 5.7e-70 239.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 41-273
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNHILTERNILKVVDSQYIVRCKYAFQDKKRLFFALEFCQG--GELFTLIKTKGF---
. .| .||.| ..|| ..|.|..|.|.|.| .|          .||. |..|||  .  .||.....||| ..|.. .|.| |  |.||..|| .|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LNENP------------------------LKPENVLIDQEGYIKLTDFGLSKILQNDNEVATSVAGTPEYLAPEILSEKGHGK-ASDWWTLGNIIYE
   ..|                          |||||.|.|.   ||..||||...|       |.. |||.|.|||.|   |.|| ..||| .| |.||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MVTGLPPFYDPNREKLFGNILTQPVKFDPRIQGNLKDLLSGLLQKDPNKRLGSKYGALE----IINHPWF
|..| |||.  . ...| .|.             .||.....|||||.||..    ||.    | .||||
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA--EALQDEWDIKCHPWF
Kinase 4069.AA AktR 141-273 49 9.3e-68 231.42 In-house 128-268 (268) Show / Hide 
Range on Protein: 141-273
Range on HMM: 128-268/268
Sequence Identity: 49% (70 aa)

LKPENVLIDQEGYIKLTDFGLSK--ILQNDNEVATSVAGTPEYLAPEILSE-KGHGKASDWWTLGNIIYEMVTGLPPFYDPNREKLFGNILTQP-VKFDP
||||| |.|..|..|.|||||||  .   ..|.|.|. |||||.|||.. . |||.|..|||..|  |||||||.||||. |.. .| .|.... .||..
LKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPY

RIQG--NLKDLLS-GLLQKDPNKRLG-SKYGALEIINHPWF
 ..   ..|||.  .||.|.|||||| .. |. || .||||
PSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 4069.AA PKA 141-273 46 4.7e-60 205.84 In-house 127-263 (263) Show / Hide 
Range on Protein: 141-273
Range on HMM: 127-263/263
Sequence Identity: 46% (65 aa)

LKPENVLIDQEGYIKLTDFGLSKILQNDNEVATSVAGTPEYLAPEILSEK-GHGKASDWWTLGNIIYEMVTGLPPFYDP--NREKLFGNILTQPVKFDPR
||||| |||..|.||.|||| .| ...   .  .. ||||||||||.. | ||||. |||.|| .||||..| |||||   .  ...  |.   .||.. 
LKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRH

IQGNL---KDLLSGLLQKDPNKRLGSKY-GALEIINHPWF
.  ..   |||.. |||.|..||.|..  |.  | ||.||
FDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 4069.AA Ciliate-E2-Unclassified 141-273 30 1.6e-57 197.42 In-house 170-352 (352) Show / Hide 
Range on Protein: 141-273
Range on HMM: 170-352/352
Sequence Identity: 30% (56 aa)

LKPENVLIDQEG---YIKLTDFGLSKILQND---------------NEVATSVAGTPEYL----APEILSEKGHG----KASDWWTLGNIIYEMVTGLPP
.||||.|.|..|   |||..|||.|| .|..               .. .....|||.|.    |||.| .....    ...|.|.|| |.|||..| .|
IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP

FYDPNREK----------------LFGNILTQPVKFDP--------RIQGNLKDLLSGLLQKDPNKRLGSKYGALEIINHPWF
|||.|.|.                |. ||. ....|..        ... . ||... ||||...|........ .|.|||||
FYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 4069.AA RSK-Unclassified 141-273 41 3.9e-55 171.39 In-house 127-283 (283) Show / Hide 
Range on Protein: 141-273
Range on HMM: 127-283/283
Sequence Identity: 41% (65 aa)

LKPENVLIDQEGYIKLTDFGLSKIL---------------------QNDNEVATSVAGTPEYLAPEILSEKGHGKASDWWTLGNIIYEMVTGLPPFYDPN
|||.|.. .||| ..||||.||.                         .   . |  || ||||||..   ||.|| |||||| ..|||  |.||.|  |
LKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNN

REKLFGNILTQPVKFD--PRIQGNLKDLLSGLLQKDPNKRLGSKYG-ALEIINHPWF
.. .| ||....|||     |  | .||.  |||. | ||||.| | | .|  || |
KNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 4069.AA RSK 141-273 42 2.7e-53 183.37 In-house 130-278 (278) Show / Hide 
Range on Protein: 141-273
Range on HMM: 130-278/278
Sequence Identity: 42% (63 aa)

LKPENVLIDQ---EGYIKLTDFGLSKILQND-NEVATSVAGTPEYLAPEILS----EKGHGKASDWWTLGNIIYEMVTGLPPFYD---PNREKLFGNILT
|||||.| |.   || |||||||..|.. .| |. . .  .| ||.|||.|     ..||.|| |||.|| ..||| || |||.     ||.... .|..
LKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQK

QP--VKFD--PRIQGNLKDLLSGLLQKDPNKRLGS-KYGALEIINHPWF
    ....  . .  . |||....|..||.||||. . .| || .||||
GKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 4069.AA Pkinase 141-273 33 1.9e-48 172.09 Pfam 134-293 (293) Show / Hide 
Range on Protein: 141-273
Range on HMM: 134-293/293
Sequence Identity: 33% (55 aa)

LKPENVLIDQEGYI----KLTDFGLSKIL-QNDNEVATSVAGTPEYLAPEILS-EKGHGKASDWWTLGNIIYEMVTGLPPFYDP------NREKLFGNIL
|||||.|||..|.|    |..||||.| .    |. .|...|||.|.|||..   ...|...|.| .| |.|||..| |||..       .  ... .|.
LKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIM

TQPVKFDPRIQ---------------------GNLKDLLSGLLQKDPNKRLGSKYGALEIINHPWF
  |..||                          ..||.....|.|||.||..    | .| .||||
GPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF
Kinase 4069.AA AGC 41-139 31 4.7e-48 121.19 In-house 1-146 (395) Show / Hide 
Range on Protein: 41-139
Range on HMM: 1-146/395
Sequence Identity: 31% (46 aa)

FNLLTIIGQGNYAKVSLVRKK------DDGQIYALKTLKRKH-IKHQV--QMNHILTE------------RNILKVVD----------SQYIVR-CKYAF
|..|..||.| . || |||||      | |..||.| || || |.     .. |..||            ||||. ..          ...||.  .|.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDKKR--LFFALEFCQ---------GG-ELFTLIK---TKGFLNEN
|||..  |.| .|...         || |||. ..    .| ..|.
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEE
Kinase 4069.AA Akt 41-139 40 4.9e-45 141.87 In-house 1-100 (264) Show / Hide 
Range on Protein: 41-139
Range on HMM: 1-100/264
Sequence Identity: 40% (40 aa)

FNLLTIIGQGNYAKVSLVRKKDDGQIY-ALKTLKRKHIKHQVQMNHILTERNILKVVDSQYIVRCKYAFQDKKRLFFALEFCQGGELFTLIKTKGFLNEN
|..| ..|.| ..|| ||.|||....| |.| || ..|  . |  |..||||||. .....||  .|.||....|.| ...|.|||||.... |.. .|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED
Kinase 4069.AA RSK 141-273 38 9.1e-43 148.4 In-house 127-271 (271) Show / Hide 
Range on Protein: 141-273
Range on HMM: 127-271/271
Sequence Identity: 38% (56 aa)

LKPENVLIDQE----GYIKLTDFGLSKILQNDNEVATSVAGTPEYLAPEILSEKGHGKASDWWTLGNIIYEMVTGLPPFYDPNREKLFGNILTQPVKF--
|||||.|.| |    | ||..|||..| |  .|. . .  .| .|.|||.|. .||..|.||| .| . ||| || .||.  .|. .. .|. ...    
LKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFS

-----DPRIQGNLKDLLSGLLQKDPNKRLGS-KYGALEIINHPWF
        |    ||||...|  ||..|||.   |. .| .||||
MTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 4069.AA AktR 41-139 42 1.3e-37 131.24 In-house 1-101 (268) Show / Hide 
Range on Protein: 41-139
Range on HMM: 1-101/268
Sequence Identity: 42% (43 aa)

FNLLTIIGQGNYAKVSLVRKK-DDGQIYALKTLKRKHIKHQVQMNHILTERNILK-VVDSQYIVRCKYAFQDKKRLFFALEFCQGGELFTLIKTKGFLNE
| .. ..|.|...|| ||.|| |....||.| .| |.|. . || |..|||||..  ..   ||. .|.||.|. |||..|.|.|||||. .|.|....|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

N
.
E
Kinase 4069.AA SGK 41-127 32 5.5e-32 95.7 In-house 1-113 (283) Show / Hide 
Range on Protein: 41-127
Range on HMM: 1-113/283
Sequence Identity: 32% (37 aa)

FNLLTIIGQGNYAKVSLVRKKDD------------------GQIYALKTLKRKHIK-------HQVQMNHILTER-NILKVVDSQYIVRCKYAFQDKKRL
| .|..||.|.. || .|..|||                  ...||.| |...||           . .||..|| .||| . .  ||  .|||| |. |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FFALEFCQGGELF
.| ... .|||.|
YFVMDYVNGGEMF
Kinase 4069.AA PKA 41-138 32 4.5e-29 102.9 In-house 1-99 (263) Show / Hide 
Range on Protein: 41-138
Range on HMM: 1-99/263
Sequence Identity: 32% (32 aa)

FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNHILTERNILKVVDSQYIVR-CKYAFQDKKRLFFALEFCQGGELFTLIKTKGFLNE
|.... .|.| ...| |.|.|..|..||.|.||.  |..  |  |...|.|||. ... .||.  .. ||| . |.. .|...|||.|. .  .| ...
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN
Kinase 4069.AA Ciliate-E2-Unclassified 41-139 23 1.3e-27 92.86 In-house 1-138 (352) Show / Hide 
Range on Protein: 41-139
Range on HMM: 1-138/352
Sequence Identity: 23% (32 aa)

FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNH---------ILTERN-------------ILKVVDSQYIVRCKYAFQDKKRLFFAL
.... .||||...|| ....|...|.||.|..| ..|..| |...         .. ...             ||.  .. .||.. |.||||. ... .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFCQGGELFTLIKTKGF-----------------LNEN
|.|.||.|.  || ...                 . |.
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQ
Kinase 4069.AA Pkinase 41-139 28 1.6e-27 98.43 Pfam 1-108 (293) Show / Hide 
Range on Protein: 41-139
Range on HMM: 1-108/293
Sequence Identity: 28% (31 aa)

FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNHIL-TERNILKVVDSQYIVRCKYAFQDKKRLFFALEFCQGG----ELFTLIK--TK
. .. .||.|....| . ..|..|.|.|.|..|..|.|......|.. .|  |.| ... .|||....|.||... . .|.|.||    .||..|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GFL--NEN
| .   |.
GCFYFSEW
Kinase 4069.AA RSK-Unclassified 41-127 37 9.5e-27 80.62 In-house 1-87 (283) Show / Hide 
Range on Protein: 41-127
Range on HMM: 1-87/283
Sequence Identity: 37% (33 aa)

FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNHILTERNILKVVDSQYIVRCKYAFQDKKRLFFALEFCQGGELF
|     ||||   || ||||||  ||||.| |... .  .     ..||.||. . .  .||.  ..|| . .|.  .|.| ||..|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFF
Kinase 4069.AA RSK 41-139 29 1.3e-25 88.54 In-house 1-101 (271) Show / Hide 
Range on Protein: 41-139
Range on HMM: 1-101/271
Sequence Identity: 29% (30 aa)

FNLLTIIGQGNYAKVSLVRKK---DDGQIYALKTLKRKHIKHQVQMNHILTERNILKVVDSQYIVRCKYAFQDKKRLFFALEFCQGGELFTLIKTKGFLN
..|.  |||| . || ...|.   | .| || | .| . ..   .     .||.||  .....||. .|.||| . ..  ..|..||.||. .  .... 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

EN
|.
ER
Kinase 4069.AA RSK 44-139 42 1.3e-24 87.09 In-house 1-104 (278) Show / Hide 
Range on Protein: 44-139
Range on HMM: 1-104/278
Sequence Identity: 42% (44 aa)

LTIIGQGNYAKVSLVRKK---DDGQIYALKTLKR-KHIKHQVQMNHILTERNILKVVD-SQYIVRCKYAFQDKKRLFFALEFCQGGELFTLIKTKGF---
|   ||| | ||.|.||.   | ||||| | ||. | ...|.   | .||||||. .  .. ||. .||||... |.  .|.| |||||| ......   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LNEN
. |.
FSED
Kinase 4069.AA S_TK_X 274-333 26 1.8e-13 51.96 SMART 1-79 (79) Show / Hide 
Range on Protein: 274-333
Range on HMM: 1-79/79
Sequence Identity: 26% (21 aa)

SDLNWESLRL--RKIIPPFKPKVD----NEIDVSYFSPDFLE--MEFSPNDE--PGSLSQPS---------IQGFSISN
....|. |.   ..| ||||||.     ...|.|.| |.| |     .| |.   .|  |.            ||. ..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 4069.AA TyrKc 41-267 16 4.9e-10 -60.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 41-267
Range on HMM: 1-280/280
Sequence Identity: 16% (47 aa)

FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNHILTERNILKVV--DSQYIVRCKYAFQDK-------KRLFFALEFCQGGELFTLIK
  |. ..| |.. .| . . |   .  | |.||  .      .  .. | .|.. .  . . |||.  .  ..       . |.  .|.. .| |   ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

TKG--------------------FLNENP-----LKPENVLIDQEGYIKLTDFGLSKILQND-----NEVATSVAG--TPE------YLAPEILSEKGHG
 ..                    .| ...     |   |.|.. .. .| .|||||. . .|     ..   ....            .||| . ..   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KASDWWTLGNIIYEMVT-GLPPFYD-----PNREKLF-----GNILTQPVK-----FDPRIQGNLKDLLSGLLQKDPNKRLGSKYGALEI
 .|| |  |  ..|. | | .| ..      . . ..     |. . ||       | ..    . .. .   . ||..|   .    ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 4069.AA Pkinase_Tyr 145-170 34 0.001165 13.02 Pfam 141-166 (270) Show / Hide 
Range on Protein: 145-170
Range on HMM: 141-166/270
Sequence Identity: 34% (9 aa)

NVLIDQEGYIKLTDFGLSKILQNDNE
|.|.. .. .| .||||.. ..|| .
NCLVTENNVVKICDFGLARDIYNDDY
Kinase 4069.AA Pkinase_Tyr 41-126 18 0.072677 6.94 Pfam 1-94 (270) Show / Hide 
Range on Protein: 41-126
Range on HMM: 1-94/270
Sequence Identity: 18% (18 aa)

FNLLTIIGQGNYAKVSLVRKK----DDGQIYALKTLKRKHIKHQVQ--MNHILTERNILKVV-DSQYIVRCKYAFQ-DKKR--LFFALEFCQGGEL
  ..  .|.|.. .| . . |    ....  | |.|  |.  .. |  .   . | .|.|   . . |||.  .   ...   ..  .|....| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL