Gene 4723 (Tetrahymena)

4723

Species: Tetrahymena
Alias: 67.m00238, 4723, TTHERM_00530600, 640, 3684.m00108, PreTt04723
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
4723.AA Protein None 419 None Fasta, JSON
4723.kin_dom Protein Kinase Domain None 230 None Fasta, JSON
4723.NA RNA None 1260 None Fasta, JSON

Protein domain

Protein domains of 4723.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 4723.AA CAMKL 8-237 38 1e-104 335.15 In-house 1-269 (297) Show / Hide 
Range on Protein: 8-237
Range on HMM: 1-269/297
Sequence Identity: 38% (106 aa)

YELGQILGQGSFAIVREVTH-STTKQQFAMKIIDKDKVQRDDSIES------------LKKEISILMMAD---HQNIVKLVEVLASRTK------IYLVL
|..|. ||.|||. |.  || .||... |.|||||.| . |. ...            ...||.|..| .   |.||.|| ||.  ...      ||||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYIRGGE--LWDLIKDRGQ----ISEDEMRKYFRQIIKAIHYCKKKNIAHRDLKPENILLDQHG--CIKVSDFGLSSLYQDP-NQIQNLLHTTCGTINYL
||. |||  | | |. .|     ..|.| |.|||||. |..|| ...|.|||.||||||||..|   ||..|||.| .|..  ..  ..|.| ||. .| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVIQN--MGYDGHMADIWSLGVILFFTISGRLPFEDE--------NVAKLLEKIVSVEYTM-PKTKMSKE
|||..|     |||  .||||.||||.. . |.|||.|.        |. .|..|| .  | . .  ..| .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-D
Kinase 4723.AA AMPK 8-231 43 1.9e-101 301.91 In-house 1-221 (254) Show / Hide 
Range on Protein: 8-231
Range on HMM: 1-221/254
Sequence Identity: 43% (98 aa)

YELGQILGQGSFAIVREVTHSTTKQQFAMKIIDKDKVQRDDSIESLKKEISILMMADHQNIVKLVEVL-ASRTKIYLVLEYIRGGELWDLIKDRGQISED
| .|. .| |.|  |   || .|... | ||..|.| . .|  |....||.|| .  |..|..| ||.  . | |..|.||. ||||.| |  .| ..|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EMRKYFRQIIKAIHYCKKKNIAHRDLKPENILLDQHGCIKVSDFGLSSLYQDPNQIQNLLHTTCGTINYLAPEVIQNMGYDGHMADIWSLGVILFFTISG
| ...| ||| .. || . .|.||||||||.|||.. .||. ||||| ...|     ..| | ||  .| |||.|..  | |   |||| ||||.  . |
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDG----EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCG

RLPFEDENVAKLLEKIVSVEYTMPK
.|||.|||...|  ||.. ||. ||
YLPFDDENTPTLYKKIKNGEYYIPK
Kinase 4723.AA CAMK 13-235 26 8.5e-97 312.43 In-house 1-372 (425) Show / Hide 
Range on Protein: 13-235
Range on HMM: 1-372/425
Sequence Identity: 26% (100 aa)

ILGQGSFAIVREVTHS-TTK-----------QQFAMKIIDKDKVQ-------------------------RDDSIESLKKEISILMM-------ADHQNI
.||.|||..|....|  ||.           |..|.|||||.|..                         |. . .....||.|...        || ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLVEVLAS-------------------RTKIYLVL---EYIRGGEL----WDLIKDRGQ---------------ISEDEMRKYFRQIIKAIHYCKKKNI
.|| ||  .                   ....|.|.   ||. ||||     | |...|.               ..|.| |.|||||. |.||| ..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPENILLDQH-----------------GCIKVSDFGLSSLYQD---------PNQIQNL------------LHTTCGTINYLA-PEVIQN-----
.||||||||||||..                 . ||..|||..  ...         ... . .            ..| |||  | | |||..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-MHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------MGYDGHMADIWSLGVILFFTISGRLPFEDE-------------NVAKLLEKIVSVEYTMPKTKMS
          |.|  .|.||.||||..  .|..||...             |  .|.||| . .|..|  ..|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFS
Kinase 4723.AA MARK 8-237 41 1.4e-85 279.68 In-house 1-234 (262) Show / Hide 
Range on Protein: 8-237
Range on HMM: 1-234/262
Sequence Identity: 41% (99 aa)

YELGQILGQGSFAIVREVTHSTTKQQFAMKIIDKDKVQRDDSIESLKKEISILMMADHQNIVKLVEVLA--SRTK-IYLVLEYIRGGELWDLIKDR--GQ
|.... .|.||.| |. ..|  |....| ||..| | ..  ...... ||.|... || ||.|| .|     ... |||..||. |||| | || .  | 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

ISEDEMRKYFRQIIKAIHYCKKKNIAHRDLKPENILLDQHG--CIKVSDFGLSSLYQDPNQI--QNLLHTTCGTINYLAPEVIQNMGYDGHMADIWSLGV
..|.| |..||||. |..|| .|||.|||.||||||.|..|   || .|||.|      ..|   ..| | |||  | |||...   |||  .|||||||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFS------ICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGV

ILFFTISGRLPFEDEN--VAKLLEKIVSVEYTMPKTKMSKE
.|.| ..|..||.. .    .| .||.. .|. |   .|||
VLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH-VSKE
Kinase 4723.AA CAMK1 8-231 40 5e-85 247.09 In-house 1-238 (276) Show / Hide 
Range on Protein: 8-231
Range on HMM: 1-238/276
Sequence Identity: 40% (98 aa)

YELGQILGQGSFAIVREVTHSTT---KQQFAMKIID-KDKVQRDDSI--ESLKKEISILM---MADHQNIVKLVEVLASRTKIYLVLEYIRGGELWDLIK
||.| ..| |.|..|...||  |   ..|.|.|.|| |. .. .|    |.|..||.|.      ||.||.|. |.  | ...|||.|.. |||| | | 
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

DRGQISEDEMRKYFRQIIKAIHYCKKKNIAHRDLKPENILL---DQHGCIK--VSDFGLSSLYQ-DPNQIQNLLHTTCGTINYLAPEVIQN---MGYDGH
..|. .|.. |.  .||..|..|. .|.|.||||||||.|.   | .  ||  ..|||||  .  | |    |. | |||. | ||||. .    .||  
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN----LMKTACGTPGYVAPEVLECKKDKPYDKA

MADIWSLGVILFFTISGRLPFEDEN-VAKLLEKIVSVEYTMPK
  |.|| |||...   |  || |||  ..|.||| . ||..|.
C-DMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPS
Kinase 4723.AA Ciliate-E2-Unclassified 8-222 29 4.2e-84 285.7 In-house 1-298 (352) Show / Hide 
Range on Protein: 8-222
Range on HMM: 1-298/352
Sequence Identity: 29% (89 aa)

YELGQILGQGSFAIVREVTHSTTKQQF-----AMKIIDKD--KVQRDDSIESLK-KEISILMMADHQN-----------------IVKLVEVLASRTKIY
|......|||.|..|... |. .| |.     ..||....  .... | ..... ||. .... .||.                 |||....  .. .||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

LVLEYIRGGELWDLIKDRGQ-----------------ISEDEMR-----KYFRQIIKAI-HYCKKKNIAHRDLKPENILLDQHG---CIKVSDFGLSSLY
.|.||..||.||. ||.|..                 ..| ...     .||.||.... ....|.|| |||.||||||.|. |   .||..|||.|. |
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

QDPNQI------------QNLLHTTCGTINYL----APEVIQNMGYDG---HMADIWSLGVILFFTISGRLPFEDENVAK----------------LLEK
|..|..            |....|.|||.||.    ||||.|. .||.   ...|||||||||.. . |..||.|.|  .                |...
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

I
|
I
Kinase 4723.AA Ciliate-E2 8-255 27 4.1e-83 282.44 In-house 1-331 (365) Show / Hide 
Range on Protein: 8-255
Range on HMM: 1-331/365
Sequence Identity: 27% (96 aa)

YELGQILGQGSFAIVREVTHSTTKQQFAMKIIDKDK------------------VQRDDSIESLKKEISILM----------------MADHQNIVKLVE
|.. ...|||.|..|.....  ...|||.|||| .|                  ... . ||..|.||.|..                  .| ||.|..|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VLA--SRTKIYLVLEYIRGGELWDLIKDR-----------GQISEDEMRKYFRQIIK---------------AIHYCKKKN-IAHRDLKPENILLDQHGC
.    ....||||.||. ||.|.|.||..           ....| |......||..               |..|...|| | |||.||||||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKVSDFGLSSLYQDPNQ----------------------------IQNLLHTTCGTINYLAPEVIQNMGYDG--------HMADIWSLGVILFFTISGRL
||..|||||  |.|.||                            .||. .|.||| .|.|||.... .||.        ...|||||||||.. ..|..
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFEDENVAKLLEKIVSVEYTMPKTKMSKEEMEELQLEEKE--EIKQTSQ
||        ...|   ..  |. .. |.    .  . ..  . |. ||
PF--------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQ
Kinase 4723.AA S_TKc 8-359 25 5.8e-82 279.53 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-359
Range on HMM: 1-231/231
Sequence Identity: 25% (94 aa)

YELGQILGQGSFAIVREVTHSTTKQQFAMKIIDKDKVQRDDSIESLKKEISILMMADHQNIVKLVEVLASRTKIYLVLEYIRG--GELWDLIKDRGQ---
||.....|.|.|. |. ..|  |....|.|||.          |....||.||.. .| ||||| .|  . ...|.|.||. |  |.| |.||.||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---ISEDEMRKYFRQIIKAIHYCKKKNIAHRDLKPENILLDQHGCIKVSDFGLSSLYQDPNQIQNLLHTTCGTINYLAPEVIQNMGYDGHMADIWSLGVI
   ..| . |.|..||..|. || ...| ||||||||||||.  .||..||||. ..          .| ||| .|.||||.   ||..  .|.||.|.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LFFTISGRLPFEDENVAKLLEKIVSVEYTMPKTKMSKEEMEELQLEEKEEIKQTSQYQRELSISSGSSELQNCESDLDGIIQDQHPTQLITKQISPIQLM
|.  ..|. ||.  .......||.                                                                            
LYEMLCGYPPFP--QMQMMFKKIG----------------------------------------------------------------------------

SLLTSNILNKMFDVKGKNEQKHLQNTYQYTPITSDKPIEEIDQTLKK-------AFEALT----PKETSYI
                                 |.  .. |.. |.|       | |||.     |   ..
---------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 4723.AA RSK 10-237 32 3.2e-74 252.87 In-house 1-245 (278) Show / Hide 
Range on Protein: 10-237
Range on HMM: 1-245/278
Sequence Identity: 32% (81 aa)

LGQI--LGQGSFAIVREVTHSTTKQQFAMKIIDKDKVQRDDS-IESLKKEISILMMAD-HQNIVKLVEVLASRTKIYLVLEYIRGGELWDLIKDRGQ---
| .   .|.|.. ..|..||. |.|..|||...| |. . .  ..  ..|..||..   |..||.| ..    .|.||..||.||||| . .. ...   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

ISEDEMRKYFRQIIKAIHYCKKKNIAHRDLKPENILLDQ---HGCIKVSDFGLSSLYQDPNQIQNLLHTTCGTINYLAPEVIQ----NMGYDGHMADIWS
.|||| . |...|..|. .  .. | ||||||||||.|.   .| ||..|||.. .   ...  ....| |.||.|.|||..     . |.| . .|.||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF--RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD-KACDWWS

LGVILFFTISGRLPFED---ENVAKLLEKIVSVE--YTMP-KTKMSKE
|||...   .|..||     .| ......| . .   |||   ..|.|
LGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQE
Kinase 4723.AA Pkinase 8-242 31 1.1e-72 252.57 Pfam 1-269 (293) Show / Hide 
Range on Protein: 8-242
Range on HMM: 1-269/293
Sequence Identity: 31% (85 aa)

YELGQILGQGSFAIVREVTHSTTKQQFAMKIIDKDKVQRDDSIESLK-KEISILMMADHQNIVKLVEVLASRTKIYLVLEYIRGG----ELWDLIK--DR
|..|...|.|||. |.. .|  | ...|.|||.|..   .  .. ..  ||.|. . .| |||.| ..  ....||.|.|| .||    .|.|.|.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GQI--SEDEMRKYFRQIIKAIHYCKKKNIAHRDLKPENILLDQHGCI----KVSDFGLSSLYQDPNQIQNLLHTTCGTINYLAPEVIQNMGYDGHMADIW
| .  ||.| ..|..||.... || ...| ||||||||||.|..| |    |..||||. ...  .  .  ..| |||..|.|||||.   |.|. .|.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGVILFFTISGRLPFEDE------NVAKLLEKIVSVEYTMPKTKMSK-------------------EEMEEL
|.|.||.  ..||.|| ..      .  .....| . ..  .  . .                    ||. ..
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF
Kinase 4723.AA CAMK-Unique 8-235 24 2.9e-72 237.8 In-house 1-327 (363) Show / Hide 
Range on Protein: 8-235
Range on HMM: 1-327/363
Sequence Identity: 24% (81 aa)

YELGQILGQGSFAIVREVTHSTTKQQFAMKIIDKDKVQRDDSIE-----------------SLKKEISILMMADHQNIVKLVEV----LASRT-------
|....|.|.|.| .|.|.. ..|.  .|.|.. | .....  ..                 .||.|..|. | ||.||.||...       |.       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------KIYLVLEYIRGGELWDLIKD--------------------RGQISE--DEMRKYFRQIIKAIHYCKKKNIAHRDLKPENILLDQHGC-----
        ..|.|.||. ||.| |.| .                    .|. ||   . . .....  |. |  ...| |||||.|||..   .      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------IKVSDFGLSSLYQDPNQIQNLLHTTCGTINYLAP--------------EVIQNMGYDGHMA---DIWSLGVILFFTISGRLPFEDENVA
           ||..||||. .|.  |.   ...|.|||. |.||              ||| . .||..     ||||||||... ..|..||. |. .
RDFPYDWSNWHIKLCDFGLCCHYNH-NKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED

--------KLLEKIVSVEY-TMPKTKMS
        ...|.| . .| . .. ...
RDYENHDKEIFECICKGDYCNFDWKMWH
Kinase 4723.AA QIK 8-224 36 7.2e-71 241.75 In-house 1-232 (272) Show / Hide 
Range on Protein: 8-224
Range on HMM: 1-232/272
Sequence Identity: 36% (86 aa)

YELGQILGQGSFAIVREVTHSTTKQQFAMKIIDKDKVQRDDSIESLKKEISILMMADHQNIVKLVEVLASRTKIYLVLEYIRGGELWDLIKDRGQ-----
|.... .| | ||.|.  .|  ||.. | ||||| .  ... .. .. |. |. | .| .|.|| .|. .   .|.| ||  .||..| .   |.     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEEN-LQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------ISEDEMRKYFRQIIKAIHYCKKKNIAHRDLKPENILLDQHGCIKVSDFGLSSLYQDPNQIQNLLHTTCGTINYLAPEVIQNMGYD
               ..|.| |. | ||. |.||| |.||.||||| ||||||.   ||. |||.| ...       || | ||.  | |||. .   ||
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQ----GQLLMTWCGSPPYAAPEMFEGKEYD

GHMADIWSLGVILFFTISGRLPFEDENVAKLLEKIVS
|  .||||.||.|.  ..| |||  ... .| ....|
GPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLS
Kinase 4723.AA Pkinase_Tyr 8-231 26 4.3e-18 61.91 Pfam 1-237 (270) Show / Hide 
Range on Protein: 8-231
Range on HMM: 1-237/270
Sequence Identity: 26% (64 aa)

YELGQILGQGSFAIVREVTHS----TTKQQFAMKIIDKDKVQRDD-SIESLKKEISILMMA-DHQNIVKLVEVLA-SRTK--IYLVLEYIRGGELWDLIK
 ..|. ||.|.|  |.. |       ||.. | |.. |..   ..  .|.. .|..|..   .|.|||.|. |    .    ||.|.||  .| | |  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

D----RGQISEDEMRKYFRQIIKAIHYCKKKNIAHRDLKPENILLDQHGCIKVSDFGLSSLY-QDPNQIQNLLHTTCGTINYLAPEVIQNMGYDGHMADI
.    .....  .. .. .|| |.  |   ||. ||||   |.|..  ...|..||||. .   | . ..   ..    |  .|||.|... .  .  |.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFT-TKSDV

WSLGVILFFTIS-GRLP-FEDENVAKLLEKIVSVEYTMPK
|| || ..  .. |. | ...   . ..|.|    | ||.
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC
Kinase 4723.AA TyrKc 8-250 22 1.9e-15 27.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-250
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YELGQILGQGSFAIVREVTHSTTKQQFAMKIIDKDKVQRDDSIESLKKEISILMMA--DHQNIVKLVEVLASR-------TKIYLVLEYIRGGELWDLIK
 .||..|| | | .|.. | .   .| | | . .|.      .| . .|..|...   .|.|||.|. |  .          ...|.||  .| | | ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

DRGQ-ISEDEMRKYFRQIIKAIHYCKKKNIAHRDLKPENILLDQHGCIKVSDFGLSSLYQDP------NQIQNL----LHTTCGTINYLAPEVIQNMGYD
...  .. ... ..  || .   |  .||. ||||   |.|..  ...|.||||||    |        .           |   |  .|||.|.   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GHMADIWSLGVILFFTIS-GRLPFEDE----NVAKLLEKIVSVEYTMPKTKM--------SKEEMEEL----------------QLEEKEEI
 .  |.|| || ..   . |  | ...      .. . . |   | ||. .           .|| ..                ..  .|..
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF