Gene 7231 (Tetrahymena)
7231
Sequence
Protein domains of 7231.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 7231.AA | CAMK | 1386-1640 | 23 | 3.4e-103 | 333.41 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 1386-1640
Range on HMM: 1-425/425
Sequence Identity: 23% (100 aa)
VIGKGAFAKVCLAVQLLTG------------KFVAIKLIDKSILRS-------------------------ESAKKRVLQEVQILKKLN------NHKHV
..|.|.|.|| |... .|. . |||| |||. |.. .. .|.|..|..|.|||. .|...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
LKLLEVFEN-------------------RKLIFIVT---EYFRGQ----DLMKMMKERNG-------------EPYTENQVRYMLTQIISGLRYIHGNMV
.||.||.|. .| ...|. || | || . .|. . .|| ..|.. ||.|...|.| . .
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
LHRDIKLDNILVDSQ-----------------LNLKIIDFGISRIILK------------------------DQKMMEQCGTPAFLA-PEIIAN------
|||.|..|||.|. |.|||||| .... . .||| ..||||.. | ||..
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
-------KGYEGFGSDLWSLGVLIYILLFGKVPFKGN-------------NLTELHRNILNGVLPLDEMR------------ETNVSQE--------AQD
| | |. .| ||.||. ||.| |. || | |. ||...|..| .. ..|.| ..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LLQKILKLKVKERINLEGIANSAWM
|..|.|. ..|...| . | ||
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 7231.AA | CAMKL | 1381-1640 | 31 | 2.7e-98 | 314.3 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 1381-1640 Range on HMM: 1-297/297 Sequence Identity: 31% (94 aa) YKVLHVIGKGAFAKVCLAVQ-LLTGKFVAIKLIDKSILR-SESAKKR-----------VLQEVQILKKLN--NHKHVLKLLEVFENRKL------IFIVT |... ..|||.|.|| ||. ..||. |||| |||. .. . .||. . .|.||.|.|| |... ||.||.|... |..|. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYFRGQD--LMKMMKERNG--EPYTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQL--NLKIIDFGISRIILK-----DQKMMEQCGTPAFL || | . |. . ... . .. .|.. | . .||.|.. |.| ... |||||..|||.|.. |.|||||| | .. . .||....||.|.. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEIIAN--KGYEGFGSDLWSLGVLIYILLFGKVPFKGNNL-----TELHRNILNGVLPLDEM-RETNVSQEAQDLLQKILKLKVKERINLEGIANSAWM ||||.. | |.|. | ||.||. | ...|..||.. .. . . . .. || ...||..|.|. . ..|.... | | || APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | 7231.AA | S_TKc | 1381-1640 | 30 | 4.5e-92 | 313.11 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1381-1640
Range on HMM: 1-231/231
Sequence Identity: 30% (84 aa)
YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQEVQILKKLNNHKHVLKLLEVFENRKLIFIVTEYFRG--QDLMKMMKERNGEP
|..| .||||||.||.... ||. |||| |. .....|.||||| .|... ||..||.. . ...|.|| | ||....|.|....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG
----YTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLNLKIIDFGISRIILKDQKMMEQCGTPAFLAPEIIANKGYEGFGSDLWSLGVLIYI
..| ..|... ||...| |.| . ..|||.| .|||.|. ..||.|||..|.. . .|||| ..|||.. || .. .| ||.|...|.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE
LLFGKVPFKGNNLTELHRNILNGVLPLDEMRETNVSQEAQDLLQKILKLKVKERINLEGIAN-------SAWM
.| |. || .. .. ..|. |.|| |...|.|. ..|. . . |.
MLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 7231.AA | Ciliate-E2-Unclassified | 1381-1640 | 25 | 8.3e-92 | 311.31 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 1381-1640
Range on HMM: 1-352/352
Sequence Identity: 25% (92 aa)
YKVLHVIGKGAFAKVCLAVQLLTGKF-------VAIKLIDKSILRSESAKKRVLQEVQILKKLNNHK----------------HVLKLLEVFENRKLIFI
||....||.|.|.||..... .... .... .|.|.... ... ..|....|| .... ...|....|.... |.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI
VTEYFRGQDLMKMMKERNG---------------EPYTENQVR-----YMLTQIISGLRYIHGN-MVLHRDIKLDNILVDSQL---NLKIIDFGISRIIL
|.||..|.||....|.|.. . ||.|.. ... ||..|| |.| . ...|||||..|||.|.. ..||||||||. .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ
----------------KDQKMMEQCGTPAFL----APEIIANKGYEG---FGSDLWSLGVLIYILLFGKVPFKGNNLTE----------------LHRNI
|.|.| .|||| .. |||.. ...|.. . .| |||||..| .|||. ||..|| .. |..||
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI
LNGVLPLDEMRE----TNVSQEAQDLLQ----KILKLKVKERINLEGIANSAWM
... . ... . ..|.||.|... |.|| . ..||..| | | |.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 7231.AA | MARK | 1381-1640 | 38 | 1e-91 | 300.07 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 1381-1640 Range on HMM: 1-262/262 Sequence Identity: 38% (103 aa) YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQEVQILKKLNNHKHVLKLLEVFE--NRKL-IFIVTEYFRGQDLMKMMKERNGE ||.| .||.|..||| ||. ..||. |||| ..| | ..| | |..|.||| .|... ||..|.| ... |... || |..|. .|.. . YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKL-DHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG PYTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQL--NLKIIDFGISRIILKDQKMMEQCGTPAFLAPEIIANKGYEGFGSDLWSLGVLIYIL . .|. | . .||.|.. | | ... |||||..|||.|.. | |||||| |..| .|| . ||||.. ||||. | |.|. | |||||. |.. RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM LFGKVPFKGNN--LTELHRNILNGVLPLDEMRETNVSQEAQDLLQKILKLKVKERINLEGIANSAWM . |..||.| . . ||...||.|. . . || |...|.|..|.. .||. .| | . || VCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | 7231.AA | AGC | 1381-1640 | 22 | 1.4e-88 | 228.42 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 1381-1640 Range on HMM: 1-395/395 Sequence Identity: 22% (88 aa) YKVLHVIGKGAFAKVCLAVQL------LTGKFVAIKLID---KSILRSESAKKRVLQE------------VQILKKLNN---------HKHVLK-LLEVF ...| |||||.| ||.|. |||. |.| .. | ... . .... | .||.|.|. | . | | | FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF ENRKL--IFIVTE----YFR-----GQ-DLMKMMKER-NGEPYTENQVRYMLTQ-------IISGLRYIHG-NMVLHRD-IKLDNILVDSQLNLKIIDFG .. . ...| | | . | .|. ....| . .|...|... . |...| |.| . . ||| .|..||| |.. ..|. ||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG ISRIILKD---------------------------------------------------QKMMEQCG--TPAFLAPEIIANKGYEGFGSDLWS--LGVLI . .. .| .. || || ..||||. |. | || ||.|. LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM YILLFGKVPFKGNNLT----------ELHRNILNGVLPLDEM------------RETNVSQEAQDLLQKILKLKVKERIN----------LEGIANSAWM | .|.|. || |.| |.. .|.|| . . . . ..|.||.||..| |. ..|. | | | | YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | 7231.AA | Ciliate-E2a | 1381-1640 | 33 | 1.5e-88 | 260.81 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 1381-1640 Range on HMM: 1-275/275 Sequence Identity: 33% (92 aa) YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQEVQILKKLNNHKHVLKLLEVFENRKLIFIVTEYFRGQDLMKMMKERNGEPYT ||.. .||||.|..| || .. ||| |.| ..| . .. |. . .|..|...| .|....|| ||.|. . ...|.||. | .|.. .|. . . YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQL-DHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE ENQVRYMLTQIIS-GLRYIHGNMVLHRDIKLDNILVD---SQ----LNLKIIDFGISRIILKDQK--MMEQCGTPAFLAPEIIANKG------YEGFGSD ..... .. |... || |.| . ..|||.|..||| . .. ...|||||| .. | ||.| | .|||| ..|||...|| | . | IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQY-DTKCD LWSLGVLIYILLFGKVPFKGNNLTELHRNILNGVLPLDEMR-ETNVSQEAQDLLQKILKLKVKERINLEGIANSAWM .||.|| .||||.|| |||| . .| .. . . .. ..|.|..||..| |. |.||. . . |. |. MWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | 7231.AA | Ciliate-E2 | 1381-1640 | 24 | 5.7e-86 | 291.92 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 1381-1640 Range on HMM: 1-365/365 Sequence Identity: 24% (92 aa) YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSE-------------------SAKKRVLQEVQILKKLN---------------NHKHVLKLL ||.. .||.|.|..|... . ...| .|||.|| .. . . .. ..|| .|....| ||....|. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY EVFE--NRKLIFIVTEYFRGQDLMKMMKER----------NGEPYTENQVRYMLTQIIS---------------GLRYIHGNM-VLHRDIKLDNILVDSQ |.|. ... |..|.||. |.||.. .|.. ...||....|. .||.. .|.|.| . ..|||||..|||. ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--- LNLKIIDFGISRIILKD---------QKMMEQ-----------------------CGTPAFLAPEIIANKGYEG--------FGSDLWSLGVLIYILLFG .||||||.|... .| .|.. . |||| ..||||. .|.|.. . .|.|||||..|..||| --IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG KVPFKGNNLTELHRNILNGVLPLDEMRET--------------NVSQEAQDLLQK----ILKLKVKERIN-LEGIANSAWM | || ..|... . ... . ..|||..||..| .|. . ..||. | | | |. KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 7231.AA | Pkinase | 1381-1640 | 28 | 1.2e-81 | 282.36 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 1381-1640 Range on HMM: 1-293/293 Sequence Identity: 28% (84 aa) YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQ--EVQILKKLNNHKHVLKLLEVFENRKLIFIVTEYFRGQ----DLMKMMKER |... .||.|.|..|.... ||| ||.| |.|. .... ... . |.||.|.| ||.....|...||... | .|.|| .| ||. ... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW NGEPY--TENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLNL----KIIDFGISRI--ILKDQKMMEQCGTPAFLAPEIIANKGYEGFGSDLW .. .. .|.... ...||..|| |.| . ..|||.|..|||.|.. .. ||.|||... . ... |. |||| ..|||.| | | .| | RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW SLGVLIYILLFGKVPFKGN------NLTELHRNILNGVLPLDEMRETNVS-----------------QEAQDLLQKILKLKVKERINLEGIANSAWM |.|...|..|.|. ||.| . .....|. . |. |. . ..| .|..|.. ..|... |.|.. | | .. |. SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 7231.AA | ULK | 1381-1640 | 27 | 6.1e-69 | 235.34 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 1381-1640 Range on HMM: 1-324/324 Sequence Identity: 27% (90 aa) YKVLHVIGKGAFA-KVCLA--VQLLT-GKFVAIKLIDKSILRS-------ESAKKRVLQEVQILKKLN--NHKH--VLKLLEVFENR--KLIFIVTEYFR | . |..|||.|. ||. . .. | ...||.| |||. .. . ... .|.||.|||. .|.. . ||...||. . |.|..|| YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN GQDLMKMMKERNGEP-------YTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLN------------LKIIDFGISRIILKD----QKMME | || . .|.....| .|.... . ||..|....| . . |||||..|||. ||| ||| .... .. |.... GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT QC------GTPAFLAPEIIA----NKGYEGFGSDLWSLGVLIYILLFGKVPFKGN--NLT----ELHRN-------ILNGVLPLDEM-RETNVSQEAQDL .. ||| . ||.|. .| | . .|.||||...| .|.||.||... .. .| .| | | .. . . ..|.| .|| CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL LQKILKLKVKERINLEGIANSAWM ... |. . |.||. | | | |. IRRMLQYDEKDRISWEEIFNHPWF |
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| Kinase | 7231.AA | ULK | 1381-1640 | 27 | 6.3e-68 | 231.97 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 1381-1640 Range on HMM: 1-329/329 Sequence Identity: 27% (90 aa) YKVLHVIGKGAFAKVCLAVQLLT----GKFVAIKLIDKSILRSES-------AKKRVLQEVQILKKLN---NHKH----VLKLLEVFENR--KLIFIVTE | . |..|||.|.||. . | .. ||.| |||. .. .. ... . .|..|.|||. .||. . ||...||. . |.|..| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME YFRGQDLMKMMKERNGEP--------YTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLN------------LKIIDFGISRIILKD----Q | | ||.. .|.....| .|.... . ||..|....| . . |||||..|||.. ||| ||| .. . .| | YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ KMMEQC------GTPAFLAPEIIA----NKGYEGFGSDLWSLGVLIYILLFGKVPFKGNNLTELH-----RN----------ILNGVLPLDEM-RETNVS || . ||| . ||.|. .| | . .|.||||...| .|.||.||... ... .. | . | . . ..| MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS QEAQDLLQKILKLKVKERINLEGIANSAWM .| .||... |. . |.||. | . | |. PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | 7231.AA | QIK | 1381-1640 | 35 | 2.7e-66 | 226.58 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 1381-1640
Range on HMM: 1-272/272
Sequence Identity: 35% (99 aa)
YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQEVQILKKLNNHKHVLKLLEVFENRKLIFIVTEYFRGQDLMKMMKE--R----
| . |||| || | || | . |||| |||| | .| .| . ||||.| | .| |. ||..| | . ..||||| . .. . . |
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQK-CYREVQIMKML-YHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK
------------NGEPYTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLNLKIIDFGISRIILKDQKMMEQCGTPAFLAPEIIANKGYEGFG
| | .||. | . .||.|. | | . |||.| ||| |...| ||.||| | ..| .| ||.|.. |||. | |.|
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK
SDLWSLGVLIYILLFGKVPFKGNNLTELHRNILNGVLPLDEMRETNVSQEAQDLLQKILKLKVKERINLEGIANSAWM
.| ||.||. |.| |. || | .|..| . .| | . .||. ..| . | . . |.. . | . ||
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFF----MSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | 7231.AA | Pkinase_Tyr | 1381-1597 | 27 | 3.2e-22 | 75.87 | Pfam | 1-232 (270) | Show / Hide |
Range on Protein: 1381-1597 Range on HMM: 1-232/270 Sequence Identity: 27% (65 aa) YKVLHVIGKGAFAKVCLAVQL----LTGKFVAIKLIDKSILRSES-AKKRVLQEVQILKKLNNHKHVLKLLEVFE-NRKL--IFIVTEYFRGQDLMKMMK . ....|.||| .|.... |. ||.| . | .| .. ..|..|.|.| .|.....|. | .. |.||.|| . || . . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR ER--NGEPYTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLNLKIIDFGISRII-LKDQK--MMEQCGTPAF-LAPEIIANKGYEGFGSDLW .. ...| | . | .|| .|. | . . |||. |.||.... || ||| .| | .|. . . . | . .||| |... . || | KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKF-TTKSDVW SLGVLIY-ILLFGKVP-FKGNNLTELHRNI-LNG | |||.. |. .|. | ..| .|. . | .| SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG |
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| Kinase | 7231.AA | TyrKc | 1381-1638 | 21 | 5.6e-17 | 51.82 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1381-1638 Range on HMM: 1-280/280 Sequence Identity: 21% (64 aa) YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQEVQILKKL-NNHKHVLKLLEVFENR-------KLIFIVTEYFRGQDLMKMMK . ....| ||| .|.... ||.| . .. .. ..| .|..|| .|.....|. | . ..||.|| . || . . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR ERNGEPYTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLNLKIIDFGISRIILKD--------QKMMEQ--CGTP----AFLAPEIIANKGY .. .. . . .. .|| .| .|.| . . |||. |.||.... || ||| || | | ... . .| .||| | |.| KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGK EGFGSDLWSLGVLIY-ILLFGKVPFKG-----NNLTELHRNILNG-VLPLDEMRETN-----VSQEAQDLLQKILKLKVKERINLEGIANSA . || || ||... |. .|. | | . .|..... .| .| . . ..| .. .. . . ..| . . | FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| UBA_CAMKL | 7231.AA | UBA_CAMKL | 1683-1720 | 31 | 3e-06 | 20.87 | In-house | 1-41 (41) | Show / Hide |
Range on Protein: 1683-1720 Range on HMM: 1-41/41 Sequence Identity: 31% (13 aa) DEKIIGQIEGF--GYSREYILRCLNKGGL-SHVNAIYKLIK ||.|| . . |..|| | ..|... |. |.| |. DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL |
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