Gene 1648 (Tetrahymena)

1648

Species: Tetrahymena
Alias: 337.m00013, PreTt01648, 1648, TTHERM_01345790, 3805.m00068, 254
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
1648.AA Protein None 356 None Fasta, JSON
1648.kin_dom Protein Kinase Domain None 295 None Fasta, JSON
1648.NA RNA None 1071 None Fasta, JSON

Protein domain

Protein domains of 1648.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 1648.AA CK2 40-334 66 1.3e-212 642.06 In-house 1-288 (288) Show / Hide 
Range on Protein: 40-334
Range on HMM: 1-288/288
Sequence Identity: 66% (197 aa)

YEVIRKLGRGKYSEVFDGISVVTKKRV--VIKVLKPVKKRKIKREIKILQILKGGPNIVELLDVVRDPASKTPSLIFEQIENVDFRSQFPNLTDLEIKFY
||||||.||||||||| || . .....  |||.||||||.|||||||||. |.|||||..|.|.|.||.||.|.|.|| ..|.|||  .. |||..|..|
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

MFEILKALDYCHSKGIMHRDVKPQNIIVDPKNKILKLIDWGLAEFYHPGTDYNVRVASRYFKGPELLVDQNYYDYSLDIWSTGTMFASMQQTQTQIIKIF
|||.|||||||||.|||||||||.||..|.... |.|||||||||||||.||||||||||.||||||||..|||||||.||.|.|||||         ||
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASM---------IF

KKEPFFQGADNQDQLIKIAKVLGTEDLHKYLRKYDLTLDVSYHKILGSYAKKPWVKFITEENKHLCHEQAIDLLSKMLIYDNALRITPKDAMEHPYF
||||||.|.||.|||.||.||||||||.|||.||...|| ..|.|.....|||| .||..|||||.|..|||.|.|||.||.. |||.|.|||||||
KKEPFFHGHDNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase 1648.AA CMGC 40-334 21 8.3e-94 308.61 In-house 1-513 (513) Show / Hide 
Range on Protein: 40-334
Range on HMM: 1-513/513
Sequence Identity: 21% (111 aa)

YEVIRKLGRGKYSEVFDGIS--------------VVTKKRVVIKVLKPVKKRKIK---------------REIKILQILK----------------GGPN
||.|.|.|.| |..|. ..                 |...| || .| ..  ..                ||||||. |.                  .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVELLDVVRDPASKTP---------------SLIFEQIEN--VDFRSQFP---------NLTDLE------------IKFYM------FEILKALD--YC
|| |.|..... |...                |.|| ...   ..  . .         .|.. .            ||..|      . ||..|.  ||
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSKG--IMHRDVKPQNIIVDPKNKI-------------------LKLIDWGLAEFYHPGTD----------------------YNVRVASRYFKGPELLV
||..  |.||| ||.|| ......                    ||..|.||| .|||  |                      |  .|..|. . ||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

-DQNY--------YDYSLDIWSTGTMFASMQQTQTQIIKIFKKEPFFQGADN-----------QDQLIKIAKVLG------------------TEDLHKY
 ...|        |... |.|| | .|| | . ...   ||...|.|.| ..           .||| || ||||                  .|.  ..
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQS--LIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNM

LRKYDLTLDVSYH---------KI-----------LGSYAKKPWVKFITEENK------------------------------HLCHEQAIDLLSKMLIY
. ...  .. ...         ..           .. . .||| ...   ..                              ..|..||||||.|||.|
IKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

DNALRITPKDAMEHPYF
| . |||...|..||||
DPDKRITAEQALQHPYF
Kinase 1648.AA Pkinase 40-334 25 7.6e-73 253.12 Pfam 1-293 (293) Show / Hide 
Range on Protein: 40-334
Range on HMM: 1-293/293
Sequence Identity: 25% (82 aa)

YEVIRKLGRGKYSEVFDGISVVTKKRVVIKVLKPVKKRKIKR-------EIKILQILKGGPNIVELLDVVRDPASKTPSLIFEQIENV----DFR-----
|...||.|.| ...|. .. . | |.|..|..| ..... |.       ||.|.. | . ||||.|.|...|  .. . ...|  |.     |       
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

SQFPNL--TDLEIKFYMFEILKALDYCHSKGIMHRDVKPQNIIVDPKNKI---LKLIDWGLAEF--YHPGTDYNVRVASRYFKGPELLVDQNYYDYSLDI
..  ..  .. |.|||| .||..|.||||.||.|||.||.|| .| .. |   .|..|.|||..  | ... ..... ....  ||.. ...||... |.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSTGTMFASMQQTQTQIIKIFKKEPFFQGA----DNQDQLIKIAKVLGTEDLHKYLRKYDLTLDVSYHKILGSYAKKPWVKFITEENKHLCHEQAIDLLS
|| | ... |            ..| |.|.    .  ||. .|....|..    .  ...  ..        .        | .... |. .| ..|...
WSCGCILYEMLC----------GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------F-HWTF-HNWSEECKDFIK

KMLIYDNALRITPKDAMEHPYF
..| .| . |.|......||.|
WCLCKDPKKRPTAEQILQHPWF
Kinase 1648.AA S_TKc 40-334 24 5.3e-64 219.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 40-334
Range on HMM: 1-231/231
Sequence Identity: 24% (78 aa)

YEVIRKLGRGKYSEVFDGISVVTKKRVVIKVLKPVKKRKIKREIKILQILKGGPNIVELLDVVRDPASKTPSLIFEQIEN-----VDFRSQFPN------
||..||.|.| ...|. .. . |...| ||..|    ..|.|||.||.   . |||| |.|| .|   .   ...| ...      |.  . .       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTDLEIKFYMFEILKALDYCHSKGIMHRDVKPQNIIVDPKNKILKLIDWGLAEFYHPGTDYNVRVASRYFKGPELLVDQNYYDY-SLDIWSTGTMFASMQ
..  ...||| .|..||.||||.||.|||.||.|| .|     .|..| ||| ..      .  . ....  ||.|     |.. . |.|| | ... | 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM-

QTQTQIIKIFKKEPFFQGADNQDQLIKIAKVLGTEDLHKYLRKYDLTLDVSYHKILGSYAKKPWVKFITEENKHLCHEQAIDLLSKMLIYDNALRITPKD
        .  . ||        |. .. |..|                                            ..|.|...|.| .| . |.|  .
--------LCGYPPFP-------QMQMMFKKIG-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-E

AME-------HPYF
|..       ||.|
ALQDEWDIKCHPWF
Kinase 1648.AA CDK 40-334 27 6.6e-59 187.03 In-house 1-284 (284) Show / Hide 
Range on Protein: 40-334
Range on HMM: 1-284/284
Sequence Identity: 27% (95 aa)

YEVIRKLGRGKYSEVFDGISVVTK-----KRVVIKVLK-PV-----KKRKIK----REIKILQILKGGPNIVELLDVVRDPAS---------KTPSLIFE
|| . |.|.| | .|. ...  |.     . | .| ..        .|  .     |||..|. |   |||| |.||. . ..         .. ...||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

QIEN-----VDFRSQFPNLTDLEIKFYMFEILKALDYCHSKGIMHRDVKPQNIIVDPKNK----ILKLIDWGLAEFYH-------PGTDYNVRVASRYFK
 ..       |            || ||. .|..|.||||..||||| ||||| .. . .     ||. | |||  ..       |   |  .|  .   
YMDHDLKKYMD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYR

GPELLVDQNYYD--YSLDIWSTGTMFASM--QQTQTQIIKIFKKEPFFQGADNQDQLIKIAKVLGT--EDLHKYLRKYDLTLDVSYHKILGSYAKKPWVK
 ||||  .  |.   . |.|| |  || |  .           ..|.|.|   .||| || ...||  ||    . |. .                    
APELLLGSKHYSGGTPIDMWSVGCIFAEMFTD---------VTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------

FITEENKHLCHEQAIDLLSKMLIYDNALRITPKDAMEHPYF
               |||.||| || . ||. ..|..||||
---------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 1648.AA CAMK 45-220 19 7.3e-48 151.89 In-house 1-321 (425) Show / Hide 
Range on Protein: 45-220
Range on HMM: 1-321/425
Sequence Identity: 19% (62 aa)

KLGRGKYSEVFDGISVVTK------------KRVVIKVLK-------------------------------PVKKRKIKREIKILQILKG------GPNI
.|||| ...|. .|   |.            ..| ||...                               |.......|||.|.. |.|       |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VELLDVVRDPASK-------TPS-----------LIF---EQIENVDF----------RSQF------------PNLTDLEIKFYMFEILKALDYCHSKG
. |..|  ||          | |           ...   | ... .           ....              .|  | ..|.  |. |..||||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IMHRDVKPQNIIVDPKN----------------KILKLIDWGLAEFYHP------------------------GTDYNVRVASRYFKG-PELLVD-----
|.||| || || .| .|                  .|.||.|.| .. |                        |  .. .. . ..   ||.|       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------QNYYDYSLDIWSTG
        . ||... |.|| |
MQNATDEEKPYYGPKCDMWSCG
Kinase 1648.AA CDC2 40-334 30 1.8e-46 140.52 In-house 1-301 (301) Show / Hide 
Range on Protein: 40-334
Range on HMM: 1-301/301
Sequence Identity: 30% (97 aa)

YEVIRKLGRGKYSEVFDGISVVTKKRVVIKVLKPVKKRKIK--------REIKILQILKGGPNIVELLDVVRDPASKTPSLIFEQIEN--VDFRS-QFP-
|. |.|.| | | .|. .. . |.. |..|  . ..             ||| .|. ||  |||| | ||.     .   ..||...     .   ..| 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIR-LEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPK

--NLTDLEIKFYMFEILKALDYCHSKGIMHRDVKPQNIIVDPKNKILKLIDWGLA-EFYHPGTDYN--VRVASRYFKGPELLVDQNYYDYSLDIWSTGTM
  ...   .| ||. ||.....||...||||| ||||| .| | . .|. | |||  |  |   |     |  .    ||.|  . .|. . |.|| |  
NKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCI

FASM--QQTQTQIIKIFKKEPFFQGADNQDQLIKIAKVLGTEDLHKYLRKYDLTLDVSYHKILGSYAKKPWVKFITE--ENKHL--CHEQAIDLLSKMLI
|| |  .           |.|.|.|    ||| || ..||| .  ..   ..|.    |    . . ..   | .    ..|..  . ...||||..||.
FAEMFMD---------VTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLP---DYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQ

YDNALRITPKDAMEHPYF
|| . ||. |.|..||||
YDPQKRISAKEALQHPYF
Kinase 1648.AA Ciliate-E2 40-218 21 4.8e-36 121.21 In-house 1-281 (365) Show / Hide 
Range on Protein: 40-218
Range on HMM: 1-281/365
Sequence Identity: 21% (63 aa)

YEVIRKLGRGKYSEVFDG--ISV---------------------VTKKRVVIKVLKPVKKRKIKREIKILQ-------------ILKGG--PNIVELLDV
|..|.|.|.| .. |. .  ..|                     |..| . .|..|. ... ||.||.|..             ||.    |||... ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VRDPASKTPSLIFEQIENVDFRS---------------QFPNLTDLEIKFYMFEILK---------------ALDYCHSKG-IMHRDVKPQNIIVDPKNK
  .   ..  |..| ..  | ..               .  ..|. |||..| .||.               || |.|||. |.||| ||.||..     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

ILKLIDWGLAEFYHPGTD--------------------------------YNVRVASRYFKGPELLVDQNY--------YDYSLDIWS
 .|.||.||. .|..  .                                .|  . . ... || |  ..|        |||. ||||
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWS
Kinase 1648.AA CAMKL 40-220 26 8.9e-35 108.3 In-house 1-223 (297) Show / Hide 
Range on Protein: 40-220
Range on HMM: 1-223/297
Sequence Identity: 26% (59 aa)

YEVIRKLGRGKYSEVFDGIS-VVTKKRVVIKVLKPVKKRK------------------IKREIKILQILK--GGPNIVELLDVVRDPAS----KTPSLIF
|.... ||.| ...|  ..    |...| ||...  |...                  |.|||.|.. |.  . |||. |..|. .|      |   |. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EQIENVD-----FRSQFPN----LTDLEIKFYMFEILKALDYCHSKGIMHRDVKPQNIIVDPKNK-ILKLIDWGLAEFYHP-----GTDYNVRVASRYFK
| ... .     .  . ..    ..  | ..|   |. |..||||.|| ||| || || .| ...  .|.|| |.. .| |     |   . .  |  . 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

GPELLVD--QNYYDYSLDIWSTG
 ||.. .  . |. .  |||| |
APEIFQGNNKPYDGPKVDIWSCG
Kinase 1648.AA Ciliate-E2-Unclassified 40-218 21 3.5e-30 101.88 In-house 1-255 (352) Show / Hide 
Range on Protein: 40-218
Range on HMM: 1-255/352
Sequence Identity: 21% (55 aa)

YEVIRKLGRGKYSEVFDGISVVT----------KKRVVIKVLKPVKKRKIKREIKILQILK------------------GGPNIVELLDVVRDPASKTPS
|..|...|.| ...|.  .   .          |.... . ..  |.  |..|.|.....|                    |.|| .... .|   ... 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQD--KQNIY

LIFEQIENVDFRS---QFPN-----------------LTDLEIK-----FYMFEILKALDYCHSKG-IMHRDVKPQNIIVDPKNK--ILKLIDWGLAEFY
.. |..|. | .    ....                 .|. ..|     ||. .||..|.|.|.|. | ||| ||.||..| ..|   .|.||.|.. .|
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

H-----PGTD------------YNVRVASRYFK----GPELLVDQNYYD---YSLDIWS
        |.            .. .. . ...     ||.|  |||..   |. ||||
QQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWS
Kinase 1648.AA RCK 134-261 33 3.4e-28 86.32 In-house 107-232 (298) Show / Hide 
Range on Protein: 134-261
Range on HMM: 107-232/298
Sequence Identity: 33% (46 aa)

IKFYMFEILKALDYCHSKGIMHRDVKPQNIIVDPK--------NKILKLIDWGLA-EFY--HPGTDYNVRVASRYFKGPELLVDQNYYDYSLDIWSTGTM
||..|. ||..|...|..|..|||.|| || . ..        . ..|..| ||. |..  .| |||   | .|.   ||.|  ..||.. .|||. |  
IKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDY---VSTRWYRAPECLLRCTYYNSPMDIWAVGCI

FASMQQTQTQIIKIFKKEPFFQGADNQDQLIKIAKVLGT
..           .  . | | |..  ||. || ||.||
MY----------ELYMLRPLFPGSSEIDQIFKICKVMGT
Kinase 1648.AA GSK 195-334 27 2.9e-19 54.96 In-house 181-328 (328) Show / Hide 
Range on Protein: 195-334
Range on HMM: 181-328/328
Sequence Identity: 27% (45 aa)

SRYFKGPELLVDQNYYDYSLDIWSTGTMFASMQQTQTQIIKIFKKEPFFQGADNQDQLIKIAKVLGT---EDLHKYLRKY--DLTLDVSYHKILGSYAKK
|||   |||. .  .|. . |.|| |. .| |          .| .|.|.| .  |||. |.|.|||   |....   .|      ..|  .| .   .|
SRYYRAPELIFGCTNYTCQIDVWSCGCVMAEM----------LKGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQK

-----------------PWVKFI--TEENKHLCHEQAIDLLSKMLIYDNALRITPKDAMEHPYF
                   . ..  |...      ..|||.||.|.||   |..| .|. ||.|
NDTKYEYQTYYHKKYRTVYMFKWCHTDMQ------DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase 1648.AA GSK 121-178 43 3.9e-19 54.53 In-house 105-162 (328) Show / Hide 
Range on Protein: 121-178
Range on HMM: 105-162/328
Sequence Identity: 43% (25 aa)

DFRSQFPNLTDLEIKFYMFEILKALDYCHSKGIMHRDVKPQNIIVDPKNKILKLIDWG
... .  ......|| ||. ....| | ||.|| |||.||||| |||.. .||. | |
HYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFG
Kinase 1648.AA RCK 40-115 34 3.3e-12 34.73 In-house 1-80 (298) Show / Hide 
Range on Protein: 40-115
Range on HMM: 1-80/298
Sequence Identity: 34% (28 aa)

YEVIRKLGRGKYSEVFDGISVVTKKRVVIKVLKPVKKRKIK-----REIKILQILKGGPNIVELLDVVRDPASKTPSLIFE
| .|..||.| |..|. .... |.. | || .|  | ....     |||| |  |.  |||..|..|.||  . . ...||
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFE
Kinase 1648.AA CAMK 303-334 31 1.2e-09 26.55 In-house 394-425 (425) Show / Hide 
Range on Protein: 303-334
Range on HMM: 394-425/425
Sequence Identity: 31% (10 aa)

CHEQAIDLLSKMLIYDNALRITPKDAMEHPYF
. ....||..||| .|   |.| .....|| .
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 1648.AA Ciliate-E2 305-334 34 2.3e-09 28.27 In-house 331-365 (365) Show / Hide 
Range on Protein: 305-334
Range on HMM: 331-365/365
Sequence Identity: 34% (12 aa)

EQAIDLLSK----MLIYDNALRIT-PKDAMEHPYF
....||..|    || .|   ||| ......||.|
QECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 1648.AA RCK 303-334 46 3.7e-09 24.91 In-house 267-298 (298) Show / Hide 
Range on Protein: 303-334
Range on HMM: 267-298/298
Sequence Identity: 46% (15 aa)

CHEQAIDLLSKMLIYDNALRITPKDAMEHPYF
|  ..|.|. ||| .|   |||.. | .||||
CSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 1648.AA TyrKc 40-237 17 4.4e-09 -75.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 40-237
Range on HMM: 1-280/280
Sequence Identity: 17% (51 aa)

YEVIRKLGRGKYSEVFDGISVVTKKRVVIKVLKPVKKRKIKREIKILQIL-KGGPNIVELLDVVRDP-----ASKTPSLIFEQIENVDFRSQF----PNL
 . ..|||.| . ||. |.       | .|.||. ... . ||..|.  | .  |||| |. |....      .. . ...|  .. | ..      |.|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

TDLEIKFYMFEILKALDYCHSKGIMHRDVKPQNIIVDPKNKILKLIDWGLAEFYHPG-------TDYNVRV--ASR------------YFKG--------
.  .   ... | .  .| |||.. |||    |. |. .. . |  | ||. . . .         | ..    ..             ..|        
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

------------------PE------------LLVDQNYYDYSLDI-------WSTGTMFASMQQ----------TQTQIIKIF
                  |.             .|.| |.    .          .  |.  |.|          | ..|...|
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 1648.AA Ciliate-E2-Unclassified 304-334 31 1.9e-08 25.4 In-house 318-352 (352) Show / Hide 
Range on Protein: 304-334
Range on HMM: 318-352/352
Sequence Identity: 31% (11 aa)

HEQAIDLLS----KMLIYDNALRITPKDAMEHPYF
...|.|...    ||| ..   |||......||.|
SPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 1648.AA CAMKL 306-334 34 1e-07 20.55 In-house 269-297 (297) Show / Hide 
Range on Protein: 306-334
Range on HMM: 269-297/297
Sequence Identity: 34% (10 aa)

QAIDLLSKMLIYDNALRITPKDAMEHPYF
...||..|||  .   |.| .. |.|| .
DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 1648.AA GSK 40-99 30 1e-05 12.86 In-house 1-70 (328) Show / Hide 
Range on Protein: 40-99
Range on HMM: 1-70/328
Sequence Identity: 30% (21 aa)

YEVIRKLGRGKYSEVFDGISV----VTKKR----VVIKVLKPVKKRKIKREIKILQILK--GGPNIVELL
|| ... |.|  . |. ..       ||.     |.||   . |. |  || .|...|.    |||| |.
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLK