23577

Species: Tetrahymena
Alias: 42.m00311, 1046, 3813.m01529, TTHERM_00394530, PreTt23577, 23577
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other

Sequence

Name Sequence Type Origin Length Description Download
23577.AA Protein None 439 None Fasta, JSON
23577.kin_dom Protein Kinase Domain None 112 None Fasta, JSON
23577.NA RNA None 1320 None Fasta, JSON

Protein domain

Protein domains of 23577.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 23577.AA Ciliate-A1 196-232 43 1.7e-09 28.42 In-house 106-142 (301) Show / Hide
Range on Protein: 196-232
Range on HMM: 106-142/301
Sequence Identity: 43% (16 aa)

LCLTIIEAVTSLHVSNIFHGDIKPQNIIIFYKNGFKL
.|. ||| . ..|  || | |.|||||.|  .. .|.
ICYQIIEGYADIHDHNILHRDLKPQNILIHFDDKWKI

Kinase 23577.AA Other-Unique 112-329 11 5.6e-09 27.25 In-house 1-249 (249) Show / Hide
Range on Protein: 112-329
Range on HMM: 1-249/249
Sequence Identity: 11% (29 aa)

SKGGYSDVCIVKDQKDRKLIRKKVTNPSAFLNELRFFQQMENEYLVNIYYYS-----------KCDQEFYLEKGDETLYSFFKKN-----TIKNRFFLFL
 |  .. .. .  .. .....| . . . ...  .  . ..|... .||.|.           .|.. |..|.  .... .....     . .... ...
IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKRE-QIYHYQIIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWYHHHCECQCQCEHWM

LCLTIIEAVTSLHVSNIFHGDIKPQNIIIF------YKNG-------------FKLDNLQQDQDICIKDIQQFLAIESFLKFDFEGFQGSPDYKFVDNEN
 |. .|.. ..|| .|..|.||.|.||.|        .|.             .|. ....  . ..  ...|   .. .  .|.. .    .  ...  
NCCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTIIIEHQHIKIMDFNNN-N-MMYFAPEF-SCRWCSPETFDYWPLGEKIDQYHFGC

INFSDL--FNAIYRNSHKEE--IKQNYKSFSQMLEKLFCVTIKFIDFQSSSKLNSVQ
..|.    ... ..... .   .....|.  ..| .. .  ....  . ....|...
YHFHMNCQHWIFHYHDV-QHWPPHESPKDI-HILICQCECCHQCM-VNPYQNPNCFY

Kinase 23577.AA Ciliate-B2 201-232 34 7.3e-08 14.47 In-house 114-145 (197) Show / Hide
Range on Protein: 201-232
Range on HMM: 114-145/197
Sequence Identity: 34% (11 aa)

IEAVTSLHVSNIFHGDIKPQNIIIFYKNGFKL
|.. . ... || | ||||||| . ... ...
IDGLIQFRMYNILHLDIKPQNILFMQNGNYVY

Kinase 23577.AA VPS15 200-224 34 4.5e-07 20.65 In-house 107-132 (296) Show / Hide
Range on Protein: 200-224
Range on HMM: 107-132/296
Sequence Identity: 34% (9 aa)

IIEAVTSLHVSN-IFHGDIKPQNIII
. .|.  .|... ..|||||..||..
TLCALEQCHKQGNVCHGDIKSENILV

Kinase 23577.AA Ciliate-A5 193-232 37 5.4e-07 20.38 In-house 101-140 (275) Show / Hide
Range on Protein: 193-232
Range on HMM: 101-140/275
Sequence Identity: 37% (15 aa)

LFLLCLTIIEAVTSLHVSNIFHGDIKPQNIIIFYKNGFKL
|...  ..| ..  |. .||.||||.||||..   . .||
LWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQDGQVKL

Kinase 23577.AA MOS 198-224 44 8.6e-07 18.32 In-house 121-147 (299) Show / Hide
Range on Protein: 198-224
Range on HMM: 121-147/299
Sequence Identity: 44% (12 aa)

LTIIEAVTSLHVSNIFHGDIKPQNIII
| .. |.. .|  || | |.||.|||.
LDVVNALQYCHHQNILHLDVKPANIIV

Kinase 23577.AA Ciliate-E2 200-243 35 1e-06 18.51 In-house 169-197 (365) Show / Hide
Range on Protein: 200-243
Range on HMM: 169-197/365
Sequence Identity: 35% (16 aa)

IIEAVTSLHVSN-IFHGDIKPQNIIIFYKNGFKLDNLQQDQDICI
||.|. .||  | |.| ||||.||..                |.|
IILALEYLHSKNNIIHRDIKPENILF----------------IKI

Kinase 23577.AA Ciliate-E3 196-224 44 2e-06 16.51 In-house 108-136 (202) Show / Hide
Range on Protein: 196-224
Range on HMM: 108-136/202
Sequence Identity: 44% (13 aa)

LCLTIIEAVTSLHVSNIFHGDIKPQNIII
.|  ||. .  .|  || |.||||.|| .
ICIQIIQGMIAIHEKNIIHSDIKPDNILV

S_TKc 23577.AA S_TKc 106-378 13 3e-06 -86.02 SMART 1-231 (231) Show / Hide
Range on Protein: 106-378
Range on HMM: 1-231/231
Sequence Identity: 13% (43 aa)

NEKLDY-SKGGYSDVCIVKDQK-DRKLIRKKVTNPSAFLNELRFFQQMENEYLVNIYYYSKCDQEFYL--EKGDE---TLYSFFKKNTI------KNRFF
 |.|.   ||... |. ... | .|.   |..     ...|..  ..   ...|..|..    ...|.  |  |    .|... ||.         .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LFLLCLTIIEAVTSLHVSNIFHGDIKPQNIIIFYKNGFKLDNLQQDQDICIKD------------IQQFLAIESFLKFDF-------------EGFQGSP
   ..  |..|.  .|  .| | |.||.|| .                | | |               ..| | . ....             | . | |
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------------HIKICDFGLARQLTTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYP

DYKFVDNENINFSDLFNAIYRNSHKEEIKQNYKSFSQMLEKLFCVTIKFIDFQSSSKLNSVQKICYYTKAFTCKKFINKMKSEYLNFLDKMYVDHYS---
 .        .   .|. |                                                              .| ..|..|. .   .   
PFP-------QMQMMFKKIG------------------------------------------------------------SPEAKDFIRKCLQKDPEKRP

TFRTILM----ILNFQYI
|   .|     | . ...
TA-EALQDEWDIKCHPWF

Kinase 23577.AA Ciliate-C3 200-235 44 4e-06 18.43 In-house 105-140 (140) Show / Hide
Range on Protein: 200-235
Range on HMM: 105-140/140
Sequence Identity: 44% (16 aa)

IIEAVTSLHVSNIFHGDIKPQNIIIFYKNGFKLDNL
|. |.  ||  || |||||..||.|  |.  |.   
ILQAIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF

Kinase 23577.AA TKL-Sp1 200-224 48 4e-06 14.58 In-house 107-131 (263) Show / Hide
Range on Protein: 200-224
Range on HMM: 107-131/263
Sequence Identity: 48% (12 aa)

IIEAVTSLHVSNIFHGDIKPQNIII
.  ||| .| .|| | |||| |...
VLQAVTFMHACNILHLDIKPANVMV