Gene 22503 (Tetrahymena)
22503
Sequence
Protein domains of 22503.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 22503.AA | PLK-Unclassified | 46-296 | 56 | 1e-186 | 626.62 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-264/264 Sequence Identity: 56% (149 aa) YEVLSKLGKGGFAKVYLAKDISSNEQYAIKVVDKSSLEKDSFKEKLNQEIKIQKSLNHENVVKYYTSFEDSQNVYIVLEYCSN---QELLDRR------- |.....||||||||.|..|.|.....||.|...||||.|.....||..||||.|||.|.|.||....|||..||||.||||.| .|...|| YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK KRLTEIEVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLNDKMVVKLADFGLSAMMKN-AQKRKTVCGTPNYIAPEVL--KNQGHDYLVDNWAIGVIVYT |||||.|||....||.|.|||.|....||||||..||||||.|.||..||||.....| ..|.||.||||||||||.| |.|||.| ||.|..|.|.|| KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT FLIGKPPFEEKEVENTLRNIKANRYSFPENCTISKEAKDFIQKILVPNPDQRLTMDQMLQHPFM .||||||||.|.|..|...||.|.|||||.|.||..|||.||.||..|||||.|.||...|||. LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY |
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| Kinase | 22503.AA | PLK | 46-296 | 56 | 1.8e-178 | 585.69 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-258/258 Sequence Identity: 56% (147 aa) YEVLSKLGKGGFAKVYLAKDISSNEQYAIKVVDKSSLEKDSFKEKLNQEIKIQKSLNHENVVKYYTSFEDSQNVYIVLEYCSN---QELLDRR-KRLTEI ||... ||||||||.| ..||.....||||||.||...|....||..|||.|...|.|.|.||....|||..|||||||||.| .....|| ||||| YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP EVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLNDKMVVKLADFGLSAMMKNA-QKRKTVCGTPNYIAPEVL--KNQGHDYLVDNWAIGVIVYTFLIGKP ||.....||.|.|||.|....||||||..|.||||.|.||..||||...... ...||.|||||||||||| ..|||.| ||.|..|.|.||.||||| EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP PFEEKEVENTLRNIKANRYSFPENCTISKEAKDFIQKILVPNPDQRLTMDQMLQHPFM ||| |.|..|...|| |.|||||.|.||.||||.|||.| .|||.|.|.||.|||||. PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF |
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| Kinase | 22503.AA | Aur | 46-296 | 41 | 1.8e-125 | 333.06 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-257/257 Sequence Identity: 41% (107 aa) YEVLSKLGKGGFAKVYLAKDISSNEQYAIKVVDKSSLEKDSFKEKLNQEIKIQKSLNHENVVKYYTSFEDSQNVYIVLEYCSNQEL---LDRR--KRLTE |. .|||| | .||||.. ... .|.||..|. ..| .. | .|||||..|||.|. |.|. |.|.|..|..||| .. || | . ||..| FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE IEVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLND-KMVVKLADFGLSAMMKNAQKRKTVCGTPNYIAPEVLKNQGHDYLVDNWAIGVIVYTFLIGKPP .. ||. |.| |||..||||.| || | . . ..|..||| |. | ..|.| ||| |..||. ..|.||. || |..||. | .. |.|| QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP FEE-KEVENTLRNIK-ANRYSFPENCTISKEAKDFIQKILVPNPDQRLTMDQMLQHPFM ||. .. |...|| .....|| . |||||||.|.|||. .| ||.|.|| ..||.. FESNENHDETYDRIKNKVDIQFPSH--ISKEAKDLISKILQHDPKQRMTLDQIMNHPWI |
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| Kinase | 22503.AA | CAMK | 51-296 | 23 | 1.6e-105 | 341.03 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 51-296
Range on HMM: 1-425/425
Sequence Identity: 23% (100 aa)
KLGKGGFAKVYLAKDISSN------------EQYAIKVVDKSSLEKD------------------------SFKEK-LNQEIKIQKS-------LNHENV
.||.|.|.||.|....... ...|||..||. | .. ...| . .||.| |. |.|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VKYYTSFED-------------------SQNVYIVL---EYCSNQELLDR-------R---------------KRLTEIEVKSHLFQIIQSLKYIHSKGV
.| | .|| ...|.|. ||||. ||.|. . .|.|| |.. ||.. ..|.||...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
IHRDLKIANIFLNDKM-----------------VVKLADFGLSAMMKN------------------------AQKRKTVCGTPNYIA-PEVLKN------
.||||| || |.|.. .|..|||...... || ||.|||| |.| ||||.
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
--------QGHDYLVDNWAIGVIVYTFLIGKPPFEEK-------------EVENTLRNIKANRYSFPENC----------------------TISKEAKD
..... .| |..||| |. | |.|||... . ......|.. .|.||. ..|.|.||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
FIQKILVPNPDQRLTMDQMLQHPFM
.|.|.|...|..|.| .| |.||.|
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 22503.AA | S_TKc | 46-296 | 35 | 7.4e-104 | 352.25 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-231/231 Sequence Identity: 35% (95 aa) YEVLSKLGKGGFAKVYLAKDISSNEQYAIKVVDKSSLEKDSFKEKLNQEIKIQKSLNHENVVKYYTSFEDSQNVYIVLEYCSN--QELLDRRKR------ ||.| |.|||.|.|||...........|||... |.. .||.| |. .|.|.||.| .|.| ...|.|.|||.. .|.|. |. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LTEIEVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLNDKMVVKLADFGLSAMMKNAQKRKTVCGTPNYIAPEVLKNQGHDY-LVDNWAIGVIVYTF ..| .... . ||.. |.|.||.|.|||||| .||.|.. ..|..||||.. . .|.||||.|.||||| |... .| |..|.|.| . RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM LIGKPPFEEKEVENTLRNIKANRYSFPENCTISKEAKDFIQKILVPNPDQRLTMDQMLQ-------HPFM | |.|||. ... ....|. |.||||||.|.|. .|..|.| . || ||.. LCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 22503.AA | PLK1 | 46-296 | 46 | 1.3e-100 | 331.48 | In-house | 1-253 (253) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-253/253 Sequence Identity: 46% (118 aa) YEVLSKLGKGGFAKVYLAKDISSNEQYAIKVVDKSSLEKDSFKEKLNQEIKIQKSLNHENVVKYYTSFEDSQNVYIVLEYCSNQELLD---RRKRLTEIE || |||||||. | .| . .| .| ||| || | |. ..|. |||.| ..|.|...||.. |||.|||||||| |. . |.. ||| .|| | YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE VKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLNDKMVVKLADFGLSAMMKNA-QKRKTVCGTPNYIAPEVLKNQGHDYLVDNWAIGVIVYTFLIGKPPFE . .. ||... .|.| . .||||||. |.||||.. ||. |||| . . ..|| ||||||||||||...|| . || |.|| |.|. |.|.|||| CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPFE EKEVENTLRNIKANRYSFPENCTISKEAKDFIQKILVPNPDQRLTMDQMLQHPFM | ...| || | |. |.. ||. |...|.|.| |.|..| |..|.|. |. TKCLKETYSRIKKNEYRIPSH--ISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF |
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| Kinase | 22503.AA | Pkinase | 46-296 | 32 | 1.7e-100 | 345.01 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-293/293 Sequence Identity: 32% (95 aa) YEVLSKLGKGGFAKVYLAKDISSNEQYAIKVVDKSSLEKDSFKEKLN-QEIKIQKSLNHENVVKYYTSFEDSQNVYIVLEYCSNQ----ELL-----DRR |....|.|.|.|..||...........|.|...|.. ... ..... .||.| |.|||.|.|..| .|||....|.|.||| . .| .|. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KRL--TEIEVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLNDKMVV----KLADFGLSAM--MKNAQKRKTVCGTPNYIAPEVLK-NQGHDYLVDNWAI ... .| |.|. . ||.. |.|.||.|.|||||| .||........ |..||||.. | . .|.||||.|.||||.. .|.... || |.. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVIVYTFLIGKPPFEEK------EVENTLRNIKANRYSFPEN--CTIS-----------------KEAKDFIQKILVPNPDQRLTMDQMLQHPFM |.|.| .| |.||| .. . ...|. ...|.. |.|| .|.|||| ..| ..| .|.| .| ||||.. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 22503.AA | CAMK1 | 46-296 | 37 | 1.1e-96 | 281.57 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-276/276 Sequence Identity: 37% (103 aa) YEVLSKLGKGGFAKVYLAKDISS---NEQYAIKVVD-KSSLEKDSF--KEKLNQEIKIQKS---LNHENVVKYYTSFEDSQNVYIVLEYCSNQELLDR-- ||. ...|.| |..|||...... ..|||||. | |....|.. .|.| .|| | |. ..|.|..| | .|. .|.|.|.... ||.|| YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV -RKRLTEIEVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLNDK---MVVK--LADFGLSAMMKNAQ-KRKTVCGTPNYIAPEVLKN---QGHDYLVDNW .. || . ||.. ..|.||||. ||||| |. . || . .| .|||||| . .. . ||.|||| |.|||||.. ...|. .| | EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW AIGVIVYTFLIGKPPFEEKE-VENTLRNIKANRYSFPEN--CTISKE-AKDFIQKILVPNPDQRLTMDQMLQHPFM |||| |. | | ||| .. .. .. || | ||.. ||.. ||||| . |...| .|.| .| |.||. SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 22503.AA | CAMKL | 46-296 | 32 | 1.3e-96 | 308.82 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-297/297 Sequence Identity: 32% (97 aa) YEVLSKLGKGGFAKVYLAKDISS-NEQYAIKVVDKSSLEKDSFKEK------------LNQEIKIQKSLN---HENVVKYYTSFEDSQN------VYIVL |... ||||.|.|| ||..|. .|..|||..||. . .| ...| . .||.|.|.|| |.|..| | .|.... .|.|. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYCSNQE-----LLDRR----KRLTEIEVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLNDKM--VVKLADFGLSAMMKN-----AQKRKTVCGTPNYI ||||. | .... .|..| | . ||. ..|.||.|..|||.| || | ... ..|..|||.|.|... || || ||.|.| EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEVLKN--QGHD-YLVDNWAIGVIVYTFLIGKPPFEEK--------EVENTLRNIKANRYSFPENCTISKEAKDFIQKILVPNPDQRLTMDQMLQHPFM |||... . .| . || |..||| |. . |. ||.. . . .. |. | .| . .| ...|.|.|.|..||..| |..| ..||.| APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | 22503.AA | PLK2 | 46-296 | 41 | 3.5e-90 | 290.59 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-257/257 Sequence Identity: 41% (108 aa) YEVLSKLGKGGFAKVYLAKDISSNEQYAIKVVDKSSLEKDSFKEKLNQEIKIQKSLNHENVVKYYTSFEDSQNVYIVLEYCSN----QEL---LDRRKRL | |||||||. | . |.... ||.|.| .| | . || .|| . | | ..|... ||| |.||.||||| . . . |. | YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL TEIEVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLNDKMVVKLADFGLSAMMKNAQKRK-TVCGTPNYIAPEVLKNQGHDYLVDNWAIGVIVYTFLIGK || || . ||. |.| |....|||||| | |.|| | || |||| | . . ... | |||||||||||| ||| | || | | || |.| TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVLNRQGHSCESDIWALGCIMYTMLCGR PPFEEKEVENTLRNIKANRYSFPENCTISKEAKDFIQKILVPNPDQRLTMDQMLQHPFM |||| . | |.|. |.| .|. . | |. | ..| |.| | .|. ..| | PPFETANLKETYRCIRHNHYHMPT--HLSPPARHLIARMLSPDPEDRPSLDHIIRHDFF |
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| Kinase | 22503.AA | Ciliate-E2 | 46-296 | 26 | 1.7e-89 | 303.66 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-365/365 Sequence Identity: 26% (102 aa) YEVLSKLGKGGFAKVYLAKDISSNEQYAIKV-------------VDKSSLEKDSFKEK----LNQEIKIQK----------------SLNHENVVKYYTS |... |.|.|.|..||..|... ..|.|||. |... .. ..|.. ..|||.| . .||| |..|.| . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FE--DSQNVYIVLEYCSNQELLD---------------RRKRLTEIEVKSHLFQIIQ---------------SLKYIHSKG-VIHRDLKIANIFLNDKMV |. | .|.|.|.|||. ..|.| |..|| |.| ||.| |.|.|||. .||||.| ||.. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- VKLADFGLSA----------------MMKNAQ-----------------KRKTVCGTPNYIAPEVLKNQG---------HDYLVDNWAIGVIVYTFLIGK .|..||||| .... . .|.||||.| |||.|.... .|| .| |..||| | .| || IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK PPFEEKEVENTLRNIKANRYSFPENC----------------TISKEAKDFIQK----ILVPNPDQRLT-MDQMLQHPFM ||| ...|| . ..||... .|.|.||.|.| .|. .|..|.| ..| |.||.. PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 22503.AA | MARK | 46-296 | 33 | 2.6e-85 | 278.84 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-262/262 Sequence Identity: 33% (89 aa) YEVLSKLGKGGFAKVYLAKDISSNEQYAIKVVDKSSLEKDSFKEKLNQEIKIQKSLNHENVVKYYTSFE--DSQN-VYIVLEYCSNQELLDR---R--KR |..| .|.|..|||.|| .. .....|||...| .| . .... ||.| |.|.|.|..|.. .| ..|. .|...||.|..||.|. . | YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LTEIEVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLNDKM--VVKLADFGLSAMMKNAQKRKTVCGTPNYIAPEVLKNQGHD-YLVDNWAIGVIVYTFL |.| | . ||. ..| |||...|||.| || . ... .|..|||.|. .. || .| |||| | |||... . | . || |. ||. |. . LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV IGKPPFEEKE--VENTLRNIKANRYSFPENCTISKEAKDFIQKILVPNPDQRLTMDQMLQHPFM |. ||... .. ..| . .|..| . .|||....||..|..||..| |... ..||.| CGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | 22503.AA | Pkinase_Tyr | 46-188 | 28 | 3.1e-18 | 62.4 | Pfam | 1-158 (270) | Show / Hide |
Range on Protein: 46-188 Range on HMM: 1-158/270 Sequence Identity: 28% (46 aa) YEVLSKLGKGGFAKVYLAKDI----SSNEQYAIKVVDKSSLEKDS-FKEKLNQEIKIQKSL-NHENVVKYYTSFE-DSQN--VYIVLEYCSN---QELLD . . |||.| | .||... . . . |.|.. | . .. ..|.. .|.|| |.| .|.|.|..| ... .|||.||. . . | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR R----RKRLTEIEVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLNDKMVVKLADFGLS . ...|| . . .|| . . | .||. ||||| |. .....||| .||||. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA |
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| Kinase | 22503.AA | TyrKc | 46-296 | 23 | 7.4e-17 | 49.83 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 1-280/280 Sequence Identity: 23% (67 aa) YEVLSKLGKGGFAKVYLAKDISSNEQYAIKVVDKSSLEKDSFKEKLNQEIKIQKSL--NHENVVKYYTSFEDS-------QNVYIVLEYCSNQELLD--R . . ||| | | .||... . .| |.|.. ... .| . .|..| ..| .|.|.|. | .. . ..||.||... |.| | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR RKR--LTEIEVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLNDKMVVKLADFGLSAMMKNA------QKRKTV----CGTP----NYIAPEVLKNQGHD ..| |. . | .|| . |.|||..||||| |. .... .|| .||||| .. .. ... .| |||... KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT YLVDNWAIGVIVY-TFLIGKPPFEE-----KEVENTLRNIKAN-RYSFPEN------CTISKEAKDFIQKILVPNPDQRLTMDQMLQHPFM | |. || . | |..| .. .. . ....|. | |.| . ..| . ... .|..| |. . | .. TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| POLO_box | 22503.AA | POLO_box | 591-613 | 37 | 0.009063 | 13.83 | Pfam | 1-24 (74) | Show / Hide |
Range on Protein: 591-613 Range on HMM: 1-24/74 Sequence Identity: 37% (9 aa) CSSKFGLAYYLNNGNVGIL-LNDG ..| |. | |.||.|... ||. YRTKYGIMYQLSNGTVQVNFFNDH |
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| POLO_box | 22503.AA | POLO_box | 689-757 | 21 | 4.5e-08 | 33.41 | Pfam | 1-74 (74) | Show / Hide |
Range on Protein: 689-757 Range on HMM: 1-74/74 Sequence Identity: 21% (16 aa) ISTKQASFFRFSNKDLQVI-FIDKSEVVITQQNK-NLYFKD--KNGTQKIHTLNHEDKSSL-PHNIRKRILYIK .||.. ...||.. || | |...... .. | .. . | .|.. . ..|.. .. |. ..|.. |.| YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK |
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