Gene 10447 (Tetrahymena)

10447

Species: Tetrahymena
Alias: TTHERM_00569170, PreTt10447, 247, 3810.m02010, 10447, 76.m00149
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
10447.AA Protein None 574 None Fasta, JSON
10447.kin_dom Protein Kinase Domain None 246 None Fasta, JSON
10447.NA RNA None 1725 None Fasta, JSON

Protein domain

Protein domains of 10447.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 10447.AA ULK 19-264 30 6.4e-106 358.19 In-house 1-329 (329) Show / Hide 
Range on Protein: 19-264
Range on HMM: 1-329/329
Sequence Identity: 30% (102 aa)

YFIDKKLGEGSFGRVYKALDQKS----NEVVAIKQYLIKGFIDNPKLQQ------LFNQELKILKQLN----SKH----VIRYIDDFSNSDS--HFLVLE
| ....||.||||.|||. ..|.    ||.||.|. ... .. ....|.      |...| ||.|.|.    .|.    .....| | .|..  .....|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCNQGDLGQLLTRKKD------KKENISEQEVIGYFKQILSGLQELHKHLVVHRDLKLDNILISQN-------------CLKIADFGFAKSFDNT---KE
|||.||| |.. ..|       .| ..||||.| .|||||.|..||||| ..|||.|..||||. .             .||||||||||..||    ..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

VTLTTL------GTQTNMAPEVLE----EKPYG-MEVDVYRC----------------DNYDDLK-RNIKKSIQN------------INFDD--PSVKIS
...|..      ||   |||..|.    .|||.  ..|..                    . |.. ..|.| |.|            ..|..  ....||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

KEMRNLLQRMICYDRRQRIRWDQIYQHELL
.|...|..||..||...|| |.....|...
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 10447.AA ULK 19-264 31 4.5e-105 355.38 In-house 1-324 (324) Show / Hide 
Range on Protein: 19-264
Range on HMM: 1-324/324
Sequence Identity: 31% (101 aa)

YFIDKKLGEGSFG-RVYKALDQKS---NEVVAIKQYLIKGFIDNPKLQQ------LFNQELKILKQLN---SKH--VIRYIDDFSNSDS--HFLVLEYCN
| ....||.||||  |||. ..|.   |..||.|.  .|........|.      |...| .|.|.|.   ...  .....| | .|..  .....||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

QGDLGQLLTRKKD-----KKENISEQEVIGYFKQILSGLQELHKHLVVHRDLKLDNILISQN-------------CLKIADFGFAKSFDNT---KEVTLT
.||| |.. ..|      .| ..||||.|..||||..|..||||| ..|||.|..||||. .             .||||||||||..||    . .. |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

TL------GTQTNMAPEVLE----EKPYG-MEVDVYRC----------------DNYDDLK----RNIK--------KSIQNINFDDPS--VKISKEMRN
..      ||   |||..|.    .|||.  ..|..                  . . |..    . |.           |.|.|..|.  .|||.|...
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LLQRMICYDRRQRIRWDQIYQHELL
|..||..||...|| |..|..|...
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 10447.AA S_TKc 19-264 25 1.8e-60 208.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-264
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

YFIDKKLGEGSFGRVYKALDQKSNEVVAIKQYLIKGFIDNPKLQQLFNQELKILKQLNSKHVIRYIDDFSNSDSHFLVLEYCNQ--GDLGQLLTRKKDKK
| | .|.|.|.||.|||. . |....||||.             . . .|..|||. . .......| | . |. ..|.|||..  ||| ... ... ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

EN--ISEQEVIGYFKQILSGLQELHKHLVVHRDLKLDNILISQNCLKIADFGFAKSFDNTKEVTLTTLGTQTNMAPEVLEEKPYGM-EVDV---------
 .  ..| ..  |..||...|. .|.| ..||||| .|||... ..||.|||.|. .        |  ||   ||||||   .||  ..|.         
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

-------YRCDNYDDLKRNIKKSIQNINFDDPSVKISKEMRNLLQRMICYDRRQRIRWDQIYQ-------HELL
       ..  ... . ..|.               |.|........ ..| ..|.   .. |       |. .
MLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 10447.AA Ciliate-E2 19-205 24 1.5e-54 185.66 In-house 1-280 (365) Show / Hide 
Range on Protein: 19-205
Range on HMM: 1-280/365
Sequence Identity: 24% (70 aa)

YFIDKKLGEGSFGRVYKA-LDQKSNEV-----------------VAIKQYLIKGFIDNP-----KLQQLFN---------QELKILKQLNSKHVIRYIDD
| . ||.|.|.|| |||.  ... ...                 |.||.| .| .. |      . .....         .|..||.|||....|.... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FS--NSDSHFLVLEYCNQGDLGQLLT--RKKDKKE-----NISEQEVIGYFKQILS---------------GLQELHKHL-VVHRDLKLDNILISQNCLK
|   . .. .||.|||..||| ...   .|| ..|     ...|.|.. ..||||.               .|..||.   ..|||.|..|||.    .|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK

IADFGFAKSFD------------------NTKEVTLT-------------TLGTQTNMAPEVLEEKP---------YGMEVDVY
|.|||..| .|                  | ...| .             ..||   ||||.|. |.         |. ..|..
IIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW
Kinase 10447.AA CAMK 24-204 21 5e-53 168.83 In-house 1-317 (425) Show / Hide 
Range on Protein: 24-204
Range on HMM: 1-317/425
Sequence Identity: 21% (68 aa)

KLGEGSFGRVYKALDQKSN------------EVVAIKQYLIKGFID------------------------NPKLQQLFNQELKILKQ-------LNSKHV
.||.|||| |... . ...            . |||| .  |   |                        .|| .. . .|..|.|.       |. ...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRYIDDFS------------NSDS--------HFLVL---EYCNQG----DLGQLLTRKKDKKEN-----------ISEQEVIGYFKQILSGLQELHKHL
|. .. .             . .          ..|.   |||  |    || . ....... |.           ..|.|.  ||.||.|... .|.| 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKLDNILISQN------------------CLKIADFGFAKSFDNTK-----------------------EVTLTTLGTQTNMA-PEVLE------
.||||||..|||...|                   .||.|||||. ||  .                       .   |  ||   || ||||.      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------EKPYGMEVDV
        ...|| ..|.
MQNATDEEKPYYGPKCDM
Kinase 10447.AA Pkinase 19-205 35 2.5e-51 181.64 Pfam 1-196 (293) Show / Hide 
Range on Protein: 19-205
Range on HMM: 1-196/293
Sequence Identity: 35% (71 aa)

YFIDKKLGEGSFGRVYKALDQKSNEVVAIKQYLIKGFIDNPKLQQLFN-QELKILKQLNSKHVIRYIDDFSNSDSHFLVLEYCNQG----DLGQLLTRKK
| | .|.|.||||.|||. .......||.|.   .  ..  |.|.... .|..|.| ||.....|..| | ..|.  .|.|||. |    ||  ....  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

DKKENI--SEQEVIGYFKQILSGLQELHKHLVVHRDLKLDNILIS--QNC---LKIADFGFAKSF-DNTKEVTLTTLGTQTNMAPEVLE-EKPYGMEVDV
... ..  ||.|.. |..|||.||. .|.. ..|||||..||||.   ..   .||.|||.|| |    .. . |  ||   |||||.   ..|| .||.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

Y
.
W
Kinase 10447.AA Ciliate-E2-Unclassified 19-205 24 1.1e-50 174.07 In-house 1-254 (352) Show / Hide 
Range on Protein: 19-205
Range on HMM: 1-254/352
Sequence Identity: 24% (62 aa)

YFIDKKLGEGSFGRVYKALDQKSNEVVAIKQYLIKGFIDNPKLQQL---FNQELKILKQLN-------------------SKHVIRYIDDFSNSDSHFLV
| | |..|.|.|| |||. . | .  .....|..|  |.. |...    ...|.|......                   . ....... | . .  ..|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LEYCNQGDLGQLLT-------------RKKDKKENISEQEVI-----GYFKQILSGLQELHKHL-VVHRDLKLDNILISQN----CLKIADFGFAKSFDN
.|||..||| | ..             ... ... ..||...      ||.|||.||. ||. . ..|||.|..|||...|    ..||.|||..|  ..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

T---------------KEVTLTTLGTQTNM----APEVLEEKPYG----MEVDVY
                .. . |. ||   |    |||||... |.     ..|..
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIW
Kinase 10447.AA STE 20-205 23 3.1e-48 166.57 In-house 1-252 (359) Show / Hide 
Range on Protein: 20-205
Range on HMM: 1-252/359
Sequence Identity: 23% (61 aa)

FID-KKLGEGSFGRVYKALDQ------KSNEV---------VAIKQYLIKGF-------------IDNPKLQQLFNQELKILKQLN--SKHVIRYIDDFS
. . .|.|.|.|| ||||..       |..||         .||||  ..               ..|.. .| . .|.||.|..|  ......|.. . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NS-------DSHFLVLEYCNQGDLGQLLTRKKDKKENIS----------EQEVIGYFKQILSG-LQELHKHLVVHRDLKLDNILISQNCLKIADFGFAKS
.        |. ....||.. | | ... .|. .... .          |.... . .||| | |. ||.| ..|||.| .|||.     |..|||....
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ

FDN----------------TKEVTLTTLGTQTNMAPEVLEE------KPYGMEVDVY
...                ... . |  ||.  |||||..       |.|.  .|..
LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIW
Kinase 10447.AA CAMKL 19-204 30 8.7e-47 147.25 In-house 1-219 (297) Show / Hide 
Range on Protein: 19-204
Range on HMM: 1-219/297
Sequence Identity: 30% (67 aa)

YFIDKKLGEGSFGRVYKALD-QKSNEVVAIKQYLIKGFIDNPKLQQLFNQ-----------ELKILKQLN---SKHVIRYIDDFSNSDS------HFLVL
| | | ||.|||| |  |.. .  .| |||| . .|.  ..|. .. .             | .|.|.||    ...|.  . . ...        .||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCNQGD--LGQLLTRKKDKKENISEQEVIGYFKQILSGLQELHKHLVVHRDLKLDNILISQNC---LKIADFGFAKSFD---NTKEVTLTTL-GTQTNM
|||  |.  | . . ....... ..| |   ||.||.|... .|.| .||||.|..|||...|    .||.||||.  ..   .... .|.|  |.   |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLEE--KPYG-MEVDV
|||...   |||   .||.
APEIFQGNNKPYDGPKVDI
Kinase 10447.AA NEK 19-204 31 3.4e-44 153.15 In-house 1-207 (286) Show / Hide 
Range on Protein: 19-204
Range on HMM: 1-207/286
Sequence Identity: 31% (65 aa)

YFIDKKLGEGSFGRVYKALDQKSNEV-----VAIKQYLIKGFIDNPKLQQLFN-QELKILKQLNSKHVIRYIDDFSN--SDSHFLVLEYCN-QGDLGQL-
| | ||.|.||||.|||. ... . .     ...|.  |.    ..| .|    .| .|||||.. ....|.| |    ... . | |||.  ||| |. 
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKK--INMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKI

--LTRKKDKKENISEQEVIGYFKQILSGLQELHKH-----LVVHRDLKLDNILISQ-NC----LKIADFGFAKSFDNTKEVTLT-TLGTQTNMAPEVLEE
  . ..|.|.....| ..  .| |....|...|..      ..|||.|  || ..  |.    .|| ||| .| ...|..   |   ||   |.|||...
KSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQN

KPYGMEVDV
|||.  .|.
KPYNNKSDI
Kinase 10447.AA Ciliate-E2c 19-194 33 1.9e-40 139.47 In-house 1-191 (310) Show / Hide 
Range on Protein: 19-194
Range on HMM: 1-191/310
Sequence Identity: 33% (66 aa)

YFIDKKLGEGSFGRVYKA--LDQKSNEVV--------AIKQYLIKGF---IDNPKLQQ-LFNQELKILKQLNSKHVIRYIDDFSNSDSHFLVLEYCNQGD
. ... || ||.| ||||     ..||          ||| .. | .   ..| | .     .|. ..|..|..|.|...| .  .   .|..||||.|.
IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT

LGQLLTRK-KDKKENISEQEVIGYFKQILSGLQELHKH-LVVHRDLKLDNILISQNCLKIADFGFAKSFDNTKEVTLTT-----LGTQTNMAPEVLE
| |..  | |     ..|.... ||.||.|....|||   . |||.|  ||||    .|||||||.| ...  ... |.      ||   |||..||
LEQYIYHKPK-----PNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQD-DNIQNTQGFNTCCGTPMYMAPQILE
Kinase 10447.AA Ciliate-E2a 19-204 31 2.2e-40 116.59 In-house 1-199 (275) Show / Hide 
Range on Protein: 19-204
Range on HMM: 1-199/275
Sequence Identity: 31% (64 aa)

YFIDKKLGEGSFGRVYKALDQKSNEVVAIKQYLIKGFIDNPKLQQLFNQELKILKQLNSKHVIRYIDDFSNSDSHFLVLEYCNQGDLGQLLTRKKDKKEN
|.. ||.|.|.||.||.|   . ..  |.| ..|| . .. | .. | .|..|..||. ...|. .. . . .. .||.|||. |.| . .  .|. .|.
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMK-KFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

ISEQEVIGYFKQILS-GLQELHKHLVVHRDLKLDNILIS---QN-----CLKIADFGFAKSFD-NTKEVTLTTLGTQTNMAPEVLEEKP------YGMEV
  .||.  . .|.|. ||. .|.  ..|||||..|||.    .|      .||.|||.|. .| . |..  .  ||   .|||||  |       |.  .
--IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKC

DV
|.
DM
Kinase 10447.AA Pkinase_Tyr 19-166 28 9.9e-24 80.99 Pfam 1-156 (270) Show / Hide 
Range on Protein: 19-166
Range on HMM: 1-156/270
Sequence Identity: 28% (46 aa)

YFIDKKLGEGSFGRVYKALDQ----KSNEVVAIKQYLIKGFIDNPKL--QQLFNQELKILKQL-NSKHVIRYIDDFS-NSDS--HFLVLEYCNQGDLGQL
  ..||||||.||.|||.       . .  ||.|          ..   .. | .|.||.||| . ....|..   .  ...  ...|.||.  |||   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LTRKKDKKENISEQEVIGYFKQILSGLQELHKHLVVHRDLKLDNILIS-QNCLKIADFG
| .... |.... .. ...  || .|.. |. .  .||||   |.|.. .|. ||.|||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 10447.AA TyrKc 19-264 19 1.1e-17 62.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-264
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

YFIDKKLGEGSFGRVYKALDQKSNEVVAIKQYLIKGFIDNPKLQQLFNQELKILKQL--NSKHVIRYIDDFSNS-------DSHFLVLEYCNQGDLGQLL
   .|||||| ||.|||.      . ||.|             .. | .|..|...|  . ....| .   . .       . ...|.||.  ||| . |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

TRKKDKKENISEQEVIGYFKQILSGLQELHKHLVVHRDLKLDNILISQNC-LKIADFGFAKSFDNT------KEVTLTTLGTQTN-------MAPEVLEE
 ....|   .. .. . .  || .| . ||.. ..||||   |.|.. |   ||.||| ..  ..       |..  .. . ...       ||||.. .
RKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

KPYGMEVDVY-------------RCDNYD-----DLKRNIKKSIQNINFDDPSVK--------ISKEMRNLLQRMICYDRRQRIRWDQIYQHELL
. .  . ||.                 ..        . . . ... .  ..            ..|| .. ..   .|  .| .  .|  ||..
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 10447.AA Ciliate-E2 217-264 22 1.6e-09 28.8 In-house 298-365 (365) Show / Hide 
Range on Protein: 217-264
Range on HMM: 298-365/365
Sequence Identity: 22% (15 aa)

IKKSIQNINFDDP---------------SVKISKEMRNLLQR----MICYDRRQRIR-WDQIYQHELL
...  ..|.|. |                 |.|.|. .|...    |...|  .||  |.|| .|. .
QQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 10447.AA Ciliate-E2c 213-264 30 2e-08 25.77 In-house 245-310 (310) Show / Hide 
Range on Protein: 213-264
Range on HMM: 245-310/310
Sequence Identity: 30% (20 aa)

LKRNIKK-------------SIQNINFDDP-SVKISKEMRNLLQRMICYDRRQRIRWDQIYQHELL
|| .|..               |||.| .   ..||.|   |...|. .|   || ||.|  ||..
LKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEEKRIDWDEIFNHECI
Kinase 10447.AA Ciliate-E2-Unclassified 222-264 21 6.5e-07 20.03 In-house 301-352 (352) Show / Hide 
Range on Protein: 222-264
Range on HMM: 301-352/352
Sequence Identity: 21% (11 aa)

QNINFDDPS-----VKISKEMRNLLQ----RMICYDRRQRIRWDQIYQHELL
.||.|.  .      ..|.|  ....    .|. ..  .|| ..|| .| ..
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 10447.AA CAMK 210-264 14 4e-06 15.13 In-house 335-425 (425) Show / Hide 
Range on Protein: 210-264
Range on HMM: 335-425/425
Sequence Identity: 14% (13 aa)

YDD-------------LKRNIKKSIQNINFD-DPSV----------------------KISKEMRNLLQRMICYDRRQRIRWDQIYQHELL
|.|               ..... |.. ..| .|.                       ..|.| ..|...| ..|  .|.  .|. .|. .
YGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 10447.AA CAMKL 206-264 18 7e-06 14.53 In-house 237-297 (297) Show / Hide 
Range on Protein: 206-264
Range on HMM: 237-297/297
Sequence Identity: 18% (12 aa)

RCDNY-----DDLKRNIKKSIQNINFDDPSVKISKEMRNLLQRMICYDRRQRIRWDQIYQHELL
..|.|     |.  .  .| ..   .... ...| . |.|...|   .  .|.  .|| .|. .
DDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 10447.AA Ciliate-E2a 223-264 31 8e-06 13.15 In-house 232-275 (275) Show / Hide 
Range on Protein: 223-264
Range on HMM: 232-275/275
Sequence Identity: 31% (14 aa)

NINFDDPS--VKISKEMRNLLQRMICYDRRQRIRWDQIYQHELL
.|.|..|    |.|||  .|...|  .|  .||   |...|   
KIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 10447.AA Pkinase 231-264 26 0.000726 14.75 Pfam 260-293 (293) Show / Hide 
Range on Protein: 231-264
Range on HMM: 260-293/293
Sequence Identity: 26% (9 aa)

VKISKEMRNLLQRMICYDRRQRIRWDQIYQHELL
...|.|.. .. ...|.|  .|. ..|| ||. .
HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 10447.AA NEK 234-264 29 0.036263 3.9 In-house 256-286 (286) Show / Hide 
Range on Protein: 234-264
Range on HMM: 256-286/286
Sequence Identity: 29% (9 aa)

SKEMRNLLQRMICYDRRQRIRWDQIYQHELL
|....||...|.. |  ||   .|| .. ..
SQDLQNLISQMLQKDPEQRPSCNQILEMPFI