Gene 15069 (Tetrahymena)

15069

Species: Tetrahymena
Alias: 15069, 3729.m00073, TTHERM_00548280, 340, PreTt15069, 71.m00196
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
15069.AA Protein None 946 None Fasta, JSON
15069.kin_dom Protein Kinase Domain None 254 None Fasta, JSON
15069.NA RNA None 2841 None Fasta, JSON

Protein domain

Protein domains of 15069.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15069.AA ULK 39-292 32 8.20000000001e-109 367.8 In-house 1-324 (324) Show / Hide 
Range on Protein: 39-292
Range on HMM: 1-324/324
Sequence Identity: 32% (106 aa)

YTLHEILGKGSFG-QVFKA--TKN---NKVYAIKMIDKPLIRKKNLQ-------KYVNNEVKVMRELK---NQN--TVRLYEAFEDKDI--LYLVMEYCN
| |...||||||| .|.|.   |.   |...|.|||||  ..||...       .  .||...|..||   ..|  .|.||. ||...   .|..|||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

QGTLFNYILKNKP----------EETECVRIFVQILKGFIEIHEKHILHRDLKPSNIFIKDG-------------VFKIADFGLAKP-------KALGSS
.|.|..|| |||.          .| |.. .| ||. || |.|.. | |||.||.|| |..|             |.||||||.||        . .  .
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

YC------GTSYFMAPEILQKK-----LHDYKVDLWSMGVILFFMIFREYPFKNS-AKLL----DEIQQKTN--PYFDPYKCLKHP---KNTQCSPNLLE
..      || ..|||.|||..      .|||.|.||.|.|.. |.. .|||...  ..     ..|...    ...  .. ...|   |. ..||.. .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNG-KEQQIYIKNQPIQFPKPPKDPKISPECKD

LFKRIFVIDPTKRISFKELYDTDLF
|..| ...|...|||. |...  .|
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 15069.AA ULK 39-292 33 2.6e-106 359.51 In-house 1-329 (329) Show / Hide 
Range on Protein: 39-292
Range on HMM: 1-329/329
Sequence Identity: 33% (109 aa)

YTLHEILGKGSFGQVFKAT---KN---NKVYAIKMIDKPLIRKKNLQKY-------VNNEVKVMRELK--------NQNTVRLYEAFEDKDI--LYLVME
| |...|||||||.|.|..   ..   |...|.|||||  ...|| . .       ..||.|.|..||        ..|.|.||. ||...   .|..||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCNQGTLFNYILKNKP-----------EETECVRIFVQILKGFIEIHEKHILHRDLKPSNIFIKDG-------------VFKIADFGLAKP-------KA
|||.|.|..|| |||.           .| |.. .| ||| || |.|.. | |||.||.|| |..|             |.||||||.||        ..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LGSSYC------GTSYFMAPEILQKK-----LHDYKVDLWSMGVILFFMIFREYPFKNSAKLLDEIQQKTNPYFDPYKC--------LKHP---KNTQCS
.  ..       || ..|||.|||..      .|||.|.||.|.|.. |.. ..||... .  . .|.... . .|...        |. |   .. |.|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PNLLELFKRIFVIDPTKRISFKELYDTDLF
|.. .|..| ...|...|||. ||..  .|
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 15069.AA S_TKc 39-292 29 8.5e-84 285.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 39-292
Range on HMM: 1-231/231
Sequence Identity: 29% (80 aa)

YTLHEILGKGSFGQVFKATKNN--KVYAIKMIDKPLIRKKNLQKYVNNEVKVMRELKNQNTVRLYEAFEDKDILYLVMEYCNQ--GTLFNYILKNKP---
|......|||.||.|.|.....  ...|||.|.          . . .|...... .  | |.||..|.| | ||.|||||..  |.|| || |...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

----EETECVRIFVQILKGFIEIHEKHILHRDLKPSNIFIKDGVFKIADFGLAKPKALGSSYCGTSYFMAPEILQKKLHDY-KVDLWSMGVILFFMIFRE
     | .. ... ||...   .|...|.||||||.||.. . . ||.|||||.     ...||| ..||||.|    ... |.| || |.||. |. ..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL---TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

YPFKNSAKLLDEIQQKTNPYFDPYKCLKHPKNTQCSPNLLELFKRIFVIDPTKRISFKELYD-------TDLF
 ||      .... .|                   || .... ..... ||.||..  |.            |
PPFP----QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15069.AA Ciliate-E2 39-292 24 6.3e-83 281.81 In-house 1-365 (365) Show / Hide 
Range on Protein: 39-292
Range on HMM: 1-365/365
Sequence Identity: 24% (92 aa)

YTLHEILGKGSFGQVFKATK-------------------------NNKVYAIKMIDKPLIRKKNLQKYVN----------NEVKVMRELKNQNTVRLYEA
| .....|.|.||.|.|...                         ..| ||.|.. |  |. ..  ....          || .....|.. | ...||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--DKDILYLVMEYCNQGTLFNYILKN------------KPEETECVRIFVQILK---------------GFIEIHEKH-ILHRDLKPSNIFIKDGVFK
|.  |.. .|||||||..|.|| || .|            .. | |. .|. |||.               .. ..|.|. |.|||.||.||..     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK

IADFGLAK---------------PKALGSS---------------------YCGTSYFMAPEILQKKL---------HDYKVDLWSMGVILFFMIFREYP
|.||||.|                . .  .                     .||| ..||||||..|          .|||.|.||.||||..|.| ..|
IIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FKNSAKLLDEIQQKTNPYFDPYKCLKHPKN---------TQCSPNLLELFKR----IFVIDPTKRIS-FKELYDTDLF
|        ..... .  |..... |. ..          ..|..   |.|.    ... || |||. .... .   |
F-------QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 15069.AA Ciliate-E2c 39-292 27 2e-81 276.85 In-house 1-310 (310) Show / Hide 
Range on Protein: 39-292
Range on HMM: 1-310/310
Sequence Identity: 27% (85 aa)

YTLHEILGKGSFGQVFKATKNN-----------------KVYAIKMIDKPLIRKKNLQKYVNNEVKVMRELKNQNTVRLYEAFEDKDILYLVMEYCNQGT
.   .|||.||.|.|.|| ..                  | .. | .|  .|  |.  . . .|.  |..... . .. |.|.  .  .||.|||||.||
IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT

LFNYILKN-KPEETECVRIFVQILKGFIEIHEK-HILHRDLKPSNIFIKDGVFKIADFGLAKPKALGSSY--------CGTSYFMAPEILQK-KLHDYKV
|  || .. ||.| .|.  | ||. .| ..|..  |.|||.||.||.|..|. ||||||..|  . .  .        |||...|||.||   .   .| 
LEQYIYHKPKPNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGKNYYTEKS

DLWSMGVILFFMIFREYPFK----------------NSAKLLDEIQQKTNPYFD----------PYKCLKHPKN--TQCSPNLLELFKRIFVIDPTKRIS
|.|| || |..|.....|..                ... .. .. | . .||           . . .. |.|     |. . .|...  . |. |||.
DIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEEKRID

FKELYDTDLF
..|. .  ..
WDEIFNHECI
Kinase 15069.AA Ciliate-E2-Unclassified 39-292 24 5.5e-77 262.08 In-house 1-352 (352) Show / Hide 
Range on Protein: 39-292
Range on HMM: 1-352/352
Sequence Identity: 24% (88 aa)

YTLHEILGKGSFGQVFKATK--NNKVYAIKMIDKPLIRKKNLQKYVNNEVKVMRELKNQN----------------------TVRLYEAFEDKDILYLVM
|......|.|.||.|.|. .  ....||.|.. |  |.|...........  | |..|..                       |.....|.||. .|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCNQGTLFNYILKNKP------------------EETECV-----RIFVQILKGF-IEIHEKHILHRDLKPSNIFIKDG----VFKIADFGLAK-----
|||..|.|..|| |.|                   .| ...     ..| |||.|.   .|...|.|||.||.||.....      ||.|||..|     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------PKALGSSYCGTSYFM----APEILQKKLHD----YKVDLWSMGVILFFMIFREYPFK--NSAK----------------LLDEI-Q
              .. . .. ||| ..|    |||.||.. .|    ||.| ||.||||..|.| .|||.  |. .                |...| |
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

QKTNPYFDPYKCLKH----PKNTQCSPNLLE-LFKRIFVIDPTKRISFKELYDTDLF
....     ... ..     .  ..  .... |...... .| |||.|...    .|
KNIQ-----FPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 15069.AA Pkinase 39-292 31 1e-75 262.66 Pfam 1-293 (293) Show / Hide 
Range on Protein: 39-292
Range on HMM: 1-293/293
Sequence Identity: 31% (92 aa)

YTLHEILGKGSFGQVFKATKNNKV--YAIKMIDKPLIRKKNLQKYVN-NEVKVMRELKNQNTVRLYEAFEDKDILYLVMEYCNQG----TLFNYIL---K
|......|.||||.|.|... .    .|.| |.|. .... .|  .. .|...|..|.  | ||||..||||| .|.|||||. |     || ||    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NKP--EETECVRIFVQILKGFIEIHEKHILHRDLKPSNIFIK-DGVF----KIADFGLAK----PKALGSSYCGTSYFMAPEILQ-KKLHDYKVDLWSMG
..   .| || ... |||.|   .|.. |.||||||.||.|. .|.     ||.||||||    ..   ...|||...||||...  . ...||| ||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

VILFFMIFREYPFKNS--------AKLLDEIQQKTNPYFDPYKCLKH-----------PKNTQCSPNLLELFKRIFVIDPTKRISFKELYDTDLF
.||. |.... ||...         .....| .. ...  |..| .            .. .  |...... |...  ||.||......   . |
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 15069.AA CAMK 44-292 20 3.9e-72 231.54 In-house 1-425 (425) Show / Hide 
Range on Protein: 44-292
Range on HMM: 1-425/425
Sequence Identity: 20% (89 aa)

ILGKGSFGQVFKATKN-N-------------KVYAIKMIDKPLIRKKN-------------------------LQKYVNNEVKVMRE-------LKNQNT
.||.||||.|....   .             . .|||.|||  ...|.                          .| | .|...|.        |.  | 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLYEAFEDKDI-------------------LYLVM---EYCNQG----TLFNYILKNKP----------------EETECVRIFVQILKGFIEIHEKHI
..|||..||..                    .|.||   |||  |     ||.|| ....                .| |. |.| ||. .   .|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDLKPSNIFIKD------------------GVFKIADFGLA--KPKALGSS-------------------------YCGTSYFMA-PEILQKKL----
 |||||| || . |                  .  ||.|||.|  ...  ..                          .||| ..|| ||.|..|     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------HDYKVDLWSMGVILFFMIFREYPFKNS---------------AKLLDEIQQKTNPYFDPY-KCLK--------------HPKNTQCSPNL
          ...|.| ||.||||..|   ..||  .                .|.  |..    . .|| . .                 .. ..|.  
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEF-HH-FVSQEC

LELFKRIFVIDPTKRISFKELYDTDLF
  | ... . ||.||.. ..  .   .
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 15069.AA AGC 39-292 20 4.4e-70 179.48 In-house 1-395 (395) Show / Hide 
Range on Protein: 39-292
Range on HMM: 1-395/395
Sequence Identity: 20% (83 aa)

YTLHEILGKGSFGQVFKATKN--------NKVYAIKMIDKPL---IRKKNLQKYVNNE------------VKVMRELK----------NQNTVR-LYEAF
. .. ..||||||.|. . |.        .|.||.|...|     |.||| ......|             ... ...          ... |. |. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDKDI--LYLVMEYCN---------QG-TLFNYIL---KNKPEETECVRIFVQ--------ILKGFIEIHE-KHILHRD-LKPSNIFIKD-GVFKIADFG
.|||   ||.||||..          |  || ..    |..  . |..|..          |. ..  .|. ..| ||| ||| || . . |  |..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKP------------------------------------------------------KALGSSYCG--TSYFMAPEILQKKLHDYKVDLWS--MGVILF
|.|                                                       ... .. ||  |  .||||||    ... .| ||  .|....
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

FMIFREYPFKNS------------AKLLDEIQQKTNPYFDPYKCL-----KHPKNTQCSPNLLELFKRIFVIDPTKRIS----------FKELYDTDLF
 |..   || .             ... . |.   . .... |         |.. . ||..  | |. .. ||.||.           ..|. .   |
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 15069.AA CAMKL 39-292 29 1.6e-64 204.74 In-house 1-297 (297) Show / Hide 
Range on Protein: 39-292
Range on HMM: 1-297/297
Sequence Identity: 29% (91 aa)

YTLHEILGKGSFGQVFKATK---NNKVYAIKMIDKPLIR-KKNLQKY-----------VNNEVKVMRELK---NQNTVRLYEAFEDKDI------LYLVM
|.. . |||||||.|  ||    ... .|||.|||  |. . . .|            .  |.. |. |.    .| ..||| .|...       .||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCNQGT--LFNYILKN-----KPEETECVRIFVQILKGFIEIHEKHILHRDLKPSNIFIK-DG--VFKIADFGLA---KP-----KALGSSYCGTSYFM
|||  |   ||.|| |.     . .| |. |.| ||. .   .|...| |||.|| || .  .|  . ||.|||..   .|       . .  ||.  .|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEILQK--KLHD-YKVDLWSMGVILFFMIFREYPFK---------NSAKLLDEIQQKTNPYFDPYKCLKHPKNTQCSPNLLELFKRIFVIDPTKRISFK
||||.|.  | .| .||| ||.||||..|.. ..||.         .   .| ... ..  |.....        . |  .  | ... . .|.||.. .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWY--------HVS-DCRDLIRKMLQVNPEKRPTIH

ELYDTDLF
..     .
QIMNHPWM
Kinase 15069.AA STE 39-292 20 4.3e-54 186.04 In-house 1-359 (359) Show / Hide 
Range on Protein: 39-292
Range on HMM: 1-359/359
Sequence Identity: 20% (76 aa)

YTLHEILGKGSFGQVFKATKN-----------------NKVYAIKMIDKPLIRKKNLQ------------KYVN---NEVKVMRELK--NQNTVRLYEAF
... |..|||.||.|.|| ..                 ....||| ...   ..|. .            . ..   .|.|.|....   .| |. | ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

EDK-------DILYLVMEYCNQGTLFNYIL-KNKPE--------------ETECVRIFVQILKG-FIEIHEKHILHRDLKPSNIFIKDGVFKIADFGLAK
...       | |...|||.. |.|   |  | ..               |..  .| .|||||    .|..|| |||.||.||..     |..|||...
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCG

-------PKALGS---------------SYCGTSYFMAPEILQK------KLHDYKVDLWSMGVILFFMIFREYPFKNSAKL--LDEIQQKTNPY-----
        . . |               . .||  .||||..|.      | .|.|.| || |  .  |.  ..|. .   .  . .|.... ..     
QLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----FDPYKCLKHPK--------------NTQCSPNLLELFKRIFVIDPTKRISFKELYD--TDLF
     ..| .   | .               ...||.. .  .. ...|| || . ..|       .
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 15069.AA NEK 39-220 32 5.6e-51 175.68 In-house 1-215 (286) Show / Hide 
Range on Protein: 39-220
Range on HMM: 1-215/286
Sequence Identity: 32% (71 aa)

YTLHEILGKGSFGQVFKATKN--NKV-----YAIKMIDKPLIRKKNLQKYVNNEVKVMRELKNQNTVRLYEAFEDKD--ILYLVMEYCN-QGTLFNY---
|.. . .|.||||.|.|. .   .|.     |..| |.      |. |. .||||.. ..||..| |. |..|....   |. |||||.  |.|..    
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

ILKNK-----PEETECVRIFVQILKGFIEIHEK-----HILHRDLKPSNIFIK-DGV----FKIADFGLAKPKALGSS-------YCGTSYFMAPEILQK
| |.|      || . ...|.|....  ..|..     .|||||.||.|||.  ..      || |||..  | |...       . || |.|.||..| 
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGIS--KVLNHTTDMAYTTQVGTPYYMSPEVCQN

KLHDYKVDLWSMGVILF
|  ..|.| || |..|.
KPYNNKSDIWSLGCVLY
Kinase 15069.AA Pkinase_Tyr 39-181 30 1.1e-17 60.58 Pfam 1-159 (270) Show / Hide 
Range on Protein: 39-181
Range on HMM: 1-159/270
Sequence Identity: 30% (49 aa)

YTLHEILGKGSFGQVFKATKN------NKVYAIKMIDKPLIRKKN--LQKYVNNEVKVMREL-KNQNTVRLYEAFE-DKDI--LYLVMEYCNQGTLFNYI
 |. . ||.|.||.|.|.| .      .   |.||. |.   ...  ...  . |.|.|..| ...| |||| .   ...   .|.||||.  | | .| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

LKN-----KPEETECVRIFVQILKGFIEIHEKHILHRDLKPSNIFIK-DGVFKIADFGLAK
 |.     ..   . . . .|| ||    ..|.. ||||   |. .. ..| ||.|||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase 15069.AA TyrKc 39-292 23 1.7e-16 43.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 39-292
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

YTLHEILGKGSFGQVFKATKNNKVYAIKMIDKPLIRKKNLQKYVNNEVKVMREL--KNQNTVRLYEAFEDK-------DILYLVMEYCNQGTLFNYILKN
 || ..|| | ||.|.|.| .    |.||. .        ..   .| ..|..|  ...| |||| .  ..       . |..||||.  | | .|. |.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

K--PEETECVRIFVQILKGFIEIHEKHILHRDLKPSNIFIKDGV-FKIADFGLAKPKALG-------SSYC-----GTS-----YFMAPEILQKKLHDYK
.      . . . .|| .|   .|.|.. ||||   |. ....   ||.||||..    .       . |      |.        |||| ....    |
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

VDLWSMGVILFFMIFREYPFKNS-----AKLLDEIQQKTNPYFDPYKCLKHPKN------TQCSPNLLELFKRIFVIDPTKRISFKELYDTDLF
 | || || .. .  .  .          .  . |..  . |      .. |.|        |.. . .. |.    || .| .|.|.   ..|
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYR-----MPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF