Gene 15762 (Tetrahymena)

15762

Species: Tetrahymena
Alias: TTHERM_01001430, 196, 3820.m00293, PreTt15762, 15762, 190.m00072
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
15762.AA Protein None 650 None Fasta, JSON
15762.kin_dom Protein Kinase Domain None 266 None Fasta, JSON
15762.NA RNA None 1953 None Fasta, JSON

Protein domain

Protein domains of 15762.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15762.AA ULK 46-311 32 2.1e-115 389.71 In-house 1-329 (329) Show / Hide 
Range on Protein: 46-311
Range on HMM: 1-329/329
Sequence Identity: 32% (108 aa)

YQIVERLGKGSFGSVYKA--EKD----GKTYALKMISKSYMKDRP------FLRKYIQNEIESMKSIN--------CVNCVKLYDYFETNLA--HFFVME
|.. ..||||||| |||.  .|.    .. .| |||.|..|.  .      .. . ..|||. || ..        . |.|||||.|||     ....||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCAEGNLFNLLHSK--------NGQGLPENEALVYFSQILNGLKTIHEKGYMHRDLKPENILIHNN-------------VAKICDFGFARPLGFN-----
||  |.|..... .        ... |.|.||. .| |||||.| .|.....|||.||.||||||.             |.||.|||||. .  .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-ELTTT----VCGTAEYMPPELHQ----QQPYD-YKADIWALGVLLYVMVFGHLPFYGQFIFQMIERQCKDKVYDTDRW---VQKFPKSKE---KADKLS
 ..|..    .|||  || |.. |    |.||. ||.||| ||...| |..|  |||.. ... ....... . ....|   ..|.|   .   .....|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PEIKDFFSKVFVYDQKQRINFFQIMSHPLI
||.||.... ..||.|.||.. .. .||..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 15762.AA ULK 46-311 33 7.29999999999e-114 384.58 In-house 1-324 (324) Show / Hide 
Range on Protein: 46-311
Range on HMM: 1-324/324
Sequence Identity: 33% (109 aa)

YQIVERLGKGSFG-SVYKA--EKD---GKTYALKMISKSYMKDRPFL------RKYIQNEIESMKSIN---CVN--CVKLYDYFETNLA--HFFVMEYCA
|.. ..|||||||  |||.  .|.   .. .| |||.|..|.. . .       . ..|||. || ..   ..|  .|||||.|||     ....|||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

EGNLFNLLHSK-------NGQGLPENEALVYFSQILNGLKTIHEKGYMHRDLKPENILIHNN-------------VAKICDFGFARPLGFNELTTTVC--
 |.|..... .       ... |.|.||. .| ||.||.| .|.....|||.||.||||||.             |.||.|||||. .  |..  ..|  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTAEYMPPELHQ----QQPYD-YKADIWALGVLLYVMVFGHLPFYGQFIFQMIER----------QCKDKVYDTDRWVQKFPKSKEKADKLS
        ||  || |.. |    |.||. ||.||| ||...| |..|  ||... . . ...          |   ..|  ....|. ...  |..|.|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQ---QIYIKNQPIQFPKPP--KDPKIS

PEIKDFFSKVFVYDQKQRINFFQIMSHPLI
||.||.... ..||.|.||.. .| .||..
PECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 15762.AA S_TKc 46-311 33 2.1e-94 320.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 46-311
Range on HMM: 1-231/231
Sequence Identity: 33% (94 aa)

YQIVERLGKGSFGSVYKAEK--DGKTYALKMISKSYMKDRPFLRKYIQNEIESMKSINCVNCVKLYDYFETNLAHFFVMEYCAE--GNLFNLLHSKNGQG
|.|.. .|||.||.|||. .  .|. .|.|.|.           . |..||. .|. .. | |||||.|..    ..|||||    |.|| ........|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPENEALVYFSQILNGLKTIHEKGYMHRDLKPENILIHNNVAKICDFGFARPLGFNELTTTVCGTAEYMPPELHQQQPYDY-KADIWALGVLLYVM
    .|| .|  |. ||...|. .|..| .||||||||||. . . ||||||.|| |      ||.||| .||.||.    .|.. |.|.|..|..|| |
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VFGHLPFYGQFIFQMIERQCKDKVYDTDRWVQKFPKSKEKADKLSPEIKDFFSKVFVYDQKQRINFFQIMS-------HPLI
. |  ||.   ...|... .                        ||| ||| .| ...| ..|.   ...        || .
LCGYPPFP--QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15762.AA CAMK 51-311 23 5.7e-90 290.04 In-house 1-425 (425) Show / Hide 
Range on Protein: 51-311
Range on HMM: 1-425/425
Sequence Identity: 23% (100 aa)

RLGKGSFGSVYKAEKDGKT--------------YALKMISKSYMKD------------------------RPFLRKYIQNEIESMKS-------INCVNC
 ||.|||| |....    |              .| |.|.|. .||                        ||. || ...||| ||.       ..  | 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLYDYFET-------------------NLAHFFVM---EYCAEG----NLFNLLHSKNG-------------QGLPENEALVYFSQILNGLKTIHEKGY
.|||...|.                   .   ..||   |||  |     ||. . .. .               ..| ||  || ||. ... .|... 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

MHRDLKPENILI-HN-----------------NVAKICDFGFARPLGF------------------------NELTTTVCGTAEYMP-PELHQQ------
.||||||||||. .|                 |  ||.|||||. .                          ... .|.||| |||. ||. ..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------QPYDYKADIWALGVLLYVMVFGHLPFYGQ------------FIFQMIERQCKDKVYD-TDRWVQKFP----------KSKE-KADKLSPEIK
        ..|..|.|.|..||.||.|. |..||||             .  . . .. .   ||  . .. . .           |.| .  ..|.| |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQECK

DFFSKVFVYDQKQRINFFQIMSHPLI
|. .|  ..| ..|..  |...|| .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 15762.AA AGC 46-311 22 2.8e-83 214.38 In-house 1-395 (395) Show / Hide 
Range on Protein: 46-311
Range on HMM: 1-395/395
Sequence Identity: 22% (89 aa)

YQIVERLGKGSFGSVYKAEK-------D-GKTYALKMISKSY-MKDRPF-LRKYIQNE------------IESMKSIN----------CVNCVK-LYDYF
....  .|||||| || ..|       | || ||.|...|.. ....     .....|             . .. .|          . . || |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETNLA--HFFVMEYCA--------EGNLFNLLHSKN--GQG-LPENEALVYFSQ-------ILNGLKTIHE-KGYMHRD-LKPENILIHN-NVAKICDFG
...     .|||||.          | .  .|| ..  ..| ..|..|  |...       |. .|  .|. .|. ||| |||||||. .    |..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FARPLGFNE---------------------------------------------------LTTTVCG--TAEYMPPELHQQQPYDYKADIWA--LGVLLY
..  .  ..                                                   .|.| ||  |.|||.||      |.. .|.|.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

VMVFGHLPFYGQ----------FIFQMIERQCKDKVYDTDRWVQKFPK--SKEKADKLSPEIKDFFSKVFVYDQKQRIN----------FFQIMSHPLI
 |..|. ||||.            ..| .. ...... ...    ||.    .. ...||| ||. .| .. | ..|.           . .|..||  
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 15762.AA Pkinase 46-311 33 2.4e-81 281.38 Pfam 1-293 (293) Show / Hide 
Range on Protein: 46-311
Range on HMM: 1-293/293
Sequence Identity: 33% (101 aa)

YQIVERLGKGSFGSVYKAEKDGKT--YALKMISKSYMKDRPFLRKYIQN--EIESMKSINCVNCVKLYDYFETNLAHFFVMEYCAEG----NLFNLLHSK
|.|....|.||||.|||. . |    .|.| |.|.  ....  ...  .  ||. ||..|. | |.|||.||..    .|||||  |     || ... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

NGQGL--PENEALVYFSQILNGLKTIHEKGYMHRDLKPENILIH-NNVA----KICDFGFARP--LGFNELTTTVCGTAEYMPPELHQ-QQPYDYKADIW
.. ..  .|.|.  |. ||| ||. .|..| .|||||||||||. |..     ||||||.|.   .  |. .||.||| .||.||... .|.|..|.|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

ALGVLLYVMVFGHLPFYGQ----------FIFQMIERQCKDKVYDTDR--------WVQKFPKSKEKADKLSPEIKDFFSKVFVYDQKQRINFFQIMSHP
..|..|| |..|..||.|.           |..  ... .   . ...        |    .  ... ...|.| ||| .. . .| |.|... ||. ||
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHW-H--F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

LI
 .
WF
Kinase 15762.AA CAMKL 46-311 33 3.1e-80 255.74 In-house 1-297 (297) Show / Hide 
Range on Protein: 46-311
Range on HMM: 1-297/297
Sequence Identity: 33% (103 aa)

YQIVERLGKGSFGSVYKAEKD---GKTYALKMISKSYMKDRPFLRKY-----------IQNEIESMKSIN---CVNCVKLYDYFETNLA------HFFVM
|.|.. ||||||| |  |.     |. .| |.| |. ....|. .|            |. ||. ||..|     | .|||. .||          . ||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCAEGN--LFNLLHSKNGQG--LPENEALVYFSQILNGLKTIHEKGYMHRDLKPENILIH-NN--VAKICDFGFA---RP--LGFNELTTTVCGTAEYM
|||  |.  ||. . .. . .  .||.||  || ||. ... .|..|  |||.||||||.  |.  ..||.||||.   ||   | ... .| ||. .||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPELHQQ--QPYD-YKADIWALGVLLYVMVFGHLPFYGQ--------FIFQMIERQCKDKVYDTDRWVQKFPKSKEKADKLSPEIKDFFSKVFVYDQKQR
.||. |   .||| .|.|||..||.||.||.|.||| ..         |  . ... ..  |..            .  ..| . .|. .|  . . ..|
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP------------IWYHVS-DCRDLIRKMLQVNPEKR

INFFQIMSHPLI
..  |||.||  
PTIHQIMNHPWM
Kinase 15762.AA Ciliate-E2 46-311 24 2.1e-79 270.14 In-house 1-365 (365) Show / Hide 
Range on Protein: 46-311
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

YQIVERLGKGSFGSVYKAEK-------------------------DGKTYALKMISKSYMKDRPFLRKYIQNEIE----------SMKSINCVNCVKLYD
| ... .|.|.||||||...                         ..| ||.|...|.  .   .  ..| .||.           ....|. | .|.|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQI-KQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

YFE--TNLAHFFVMEYCAEGNLFNLLH---SKNGQGLP------ENEALVYFSQILN---------------GLKTIHEKG-YMHRDLKPENILIHNNVA
.|.  ..   ..|||||  |.|| ..     | .. ..      |.|.. .. |||.               .|. .|.|.  .|||.||||||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----I

KICDFGFARPLGFN--------------------------------ELTTTVCGTAEYMPPELHQ---------QQPYDYKADIWALGVLLYVMVFGHLP
||.|||... .  .                                ... |.|||..||.|| ..         |..||||.|||.|||.|| |.|| .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYGQFIFQMIERQCKDKVYDTDRWVQK----FPKSKE------------KADKLSPEIKDFFSK----VFVYDQKQRIN-FFQIMSHPLI
|                     .  ..    ||. .             . .|.|.| ||...|     ...|...||. . ||. || .
F--------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 15762.AA Ciliate-E2-Unclassified 46-311 27 4.2e-76 259.14 In-house 1-352 (352) Show / Hide 
Range on Protein: 46-311
Range on HMM: 1-352/352
Sequence Identity: 27% (99 aa)

YQIVERLGKGSFGSVYKAEK--DGKTYALKMISKSYMKDRPFLRK--YIQNEIESMKSIN-------------------CVNCVKLYDYFETNLAHFFVM
| |.. .|.|.||.|||...  ... ||.|...|. ....   ..   | ||.. |....                   . . ||....|..    ..||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCAEGNLFNLLHSKNG---------------QGLPENEAL-----VYFSQILNGLKTIHEKG-YMHRDLKPENILIHNN----VAKICDFGFARPLGFN
|||  |.|.. . ....               . ..|..|.      || |||.||. .|.|.   |||.||||||..||      ||.|||... .. |
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

----------------ELTTTVCGTAEYM----PPELHQQQPYD----YKADIWALGVLLYVMVFGHLPFYGQFIFQ----------------MIERQCK
                ....|.||| .||    .||. |.| ||    ||.|||.|||.|| |.|| .|||..   |                ... ...
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

DKVYDTDRWVQKFPKSKEKADKLSPEIKDFFS----KVFVYDQKQRINFFQIMSHPLI
 ...    . |.        ...||| ||| .    | .......||.| ||. ||..
KNIQFPKFPWQQ------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 15762.AA MARK 46-311 31 1.5e-66 216.6 In-house 1-262 (262) Show / Hide 
Range on Protein: 46-311
Range on HMM: 1-262/262
Sequence Identity: 31% (87 aa)

YQIVERLGKGSFGSVYKA--EKDGKTYALKMISKSYMKDRPFLRKYIQNEIESMKSINCVNCVKLYDYFE--TNLA-HFFVMEYCAEGNLFNLLHSKNGQ
| ..  .|.||.. |..|   . |. .|.|.. | . ...|  .| .. ||| ||...  |..||....|  |.    ...|||. .|.|.. . .. . 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEK-FKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

GLPENEALVYFSQILNGLKTIHEKGYMHRDLKPENILIHNN---VAKICDFGFARPLGFNELTTTVCGTAEYMPPELHQQQPYD-YKADIWALGVLLYVM
 |.|.|| ..|.||. ...  |.|.  |||.|||||||  |    .||.||||..    ... .| ||| .||.||. ...||| .|.|||.|||.||.|
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

VFGHLPFYGQF--IFQMIERQCKDKVYDTDRWVQKFPKSKEKADKLSPEIKDFFSKVFVYDQKQRINFFQIMSHPLI
| |..|| |.   . ..     . |..  . ..  .         .|.|.... ..... . ..|.   .||.|| .
VCGYFPFDGDTQDYKEL-----YKKILRGKYDIPCH---------VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 15762.AA STE 46-311 23 9.4e-61 208.15 In-house 1-359 (359) Show / Hide 
Range on Protein: 46-311
Range on HMM: 1-359/359
Sequence Identity: 23% (87 aa)

YQIVERLGKGSFGSVYKA-----------------EKDGKTYALKMISKSY-------------MKDRPFLRKYIQNEIESMKSIN--CVNCVKLYDYFE
....|..|||.||.||||                 .. |. .| | ....              ... .  .. |..||. ||  |  . | || |....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TNL-------AHFFVMEYCAEGNLFNLLHSKNGQGLP------------ENEALVYFSQILNG-LKTIHEKGYMHRDLKPENILIHNNVAKICDFGFARP
 .          . .|||.. | |  ....| | | |            |..  ..  ||| | |. .|.....|||.|| |||.    .|.||||..  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ

LGFN-----------------ELTTTVCGTAEYMPPELHQQ------QPYDYKADIWALGVLLYVMVFGHLPFYGQFIFQMIERQC--------------
|  .                 . ..|..||  .| ||  ||      ..||.|.||| || ..  |. |. |.     .... .                
LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCI

--------KDKVYDTDRWVQKFPKSKEKA--------DKLSPEIKDFFSKVFVYDQKQRINFFQIMS--HPLI
        .|.. . .   .        .        .|.||| ||| .| ...| ..| .  | ..  || |
VNGPPPPLPDHLSQNEM-IS--------YGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 15762.AA Ciliate-E2c 46-244 34 5.3e-53 182.39 In-house 1-220 (310) Show / Hide 
Range on Protein: 46-244
Range on HMM: 1-220/310
Sequence Identity: 34% (77 aa)

YQIVERLGKGSFGSVYKA--------EKDG---------KTYALKMISKSYMKDRPFLRKYIQNEIESMKSINCVNCVKLYDYFETNLAHFFVMEYCAEG
. . . ||.||.|.||||        |. .         | ..|| .  .  .... ..  | .||..||. |  . .| || . |    ...|||| .|
IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKE-SIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGG

NLFNLLHSK-NGQGLPENEALVYFSQILNGLKTIHEK-GYMHRDLKPENILIHNNVAKICDFGFARPLGFNELT-TT----VCGTAEYMPPELHQQ-QPY
.|  .. .| .   . | . | |||||....| .|.. .  |||.||||||||| . ||.||||..     . . |.    .|||  || |.     . |
TLEQYIYHKPK---PNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGKNYY

DYKADIWALGVLLYVMVFGHLPFY
 .|.||| |||.|| |..  ||..
TEKSDIWSLGVTLYYMLCYKLPWE
Kinase 15762.AA Pkinase_Tyr 46-234 29 1.9e-18 63.12 Pfam 1-205 (270) Show / Hide 
Range on Protein: 46-234
Range on HMM: 1-205/270
Sequence Identity: 29% (62 aa)

YQIVERLGKGSFGSVYKAEKD------GKTYALKMISKSYMKD-RPFLRKYIQNEIESMKSI-NCVNCVKLYDYFE-TNLA--HFFVMEYCAEGNLFNLL
 .. . ||.|.||.|||.. .      . . | ||.  ..|..    .|.   .|.. ||.. .. | |.||           .. ||||.. |.| . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN--CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HSK--NGQGLPENEALVYFSQILNGLKTIHEKGYMHRDLKPENILIH-NNVAKICDFGFARPLGFNELTT-TVCGTAE----YMPPELHQQQPYDYKADI
...  ..| |.  . | .  || .|.   ..|.. ||||   |.|.. |||.|||||| || . .|. .  .. | .      |.||  .   .  | |.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

WALGVLLY
|. |||..
WSFGVLMW
Kinase 15762.AA TyrKc 46-314 21 1.9e-15 27.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 46-314
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

YQIVERLGKGSFGSVYKAEKDGKTYALKMISKSYMKDRPFLRKYIQNEIESMKSI--NCVNCVKLYDYFETN-------LAHFFVMEYCAEGNLFNLLHS
 .  . || | || |||.. .  . | ||. ..        |. . .|.. |...  .  | |.|| .  .          .. ||||.. |.| . |..
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KNGQGLPENEALVYFSQILNGLKTIHEKGYMHRDLKPENILIHNNV-AKICDFGFARPLGFN-------ELTTT----VC---GTAEYMPPELHQQQPYD
. .. |.  . | .  || .|   .|.|.. ||||   |.|...|  .||.||| .| ..         .  ..     .        |.||  .   . 
HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

YKADIWALGVLLY-VMVFGHLPFYG-----QFIFQMIERQCKDKVYDTDRWVQKFPKSKEKADKL-----SPEIKDFFSKVFVYDQKQRINFFQIMSHPL
 | |.|. ||... .. .|  | .|        ...||       |  ..   . |.. .    .     ..|. .  ..   .| ..| .| .|     
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIE-------YVKQGYRMPQPPNDY--P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----

IEKM
.|..
HECF
Kinase 15762.AA Ciliate-E2c 269-311 30 8.8e-08 23.45 In-house 270-310 (310) Show / Hide 
Range on Protein: 269-311
Range on HMM: 270-310/310
Sequence Identity: 30% (13 aa)

KFPKSKEKADKLSPEIKDFFSKVFVYDQKQRINFFQIMSHPLI
.||.. |.  ..|.|.|... |. ..| . ||.. .|  |..|
HFPENYEQ--NISQEVKQLIHKMLQVDEEKRIDWDEIFNHECI