Gene 3032 (Tetrahymena)

3032

Species: Tetrahymena
Alias: 3674.m00085, 695, 106.m00172, PreTt03032, TTHERM_00691940, 3032
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
3032.AA Protein None 595 None Fasta, JSON
3032.kin_dom Protein Kinase Domain None 258 None Fasta, JSON
3032.NA RNA None 1788 None Fasta, JSON

Protein domain

Protein domains of 3032.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 3032.AA ULK 16-273 40 6.7e-144 484.35 In-house 1-324 (324) Show / Hide 
Range on Protein: 16-273
Range on HMM: 1-324/324
Sequence Identity: 40% (130 aa)

VVVNKKLGKGAFG-TVFRGFCEDDE--NKLVAAKQIPIKNISNSDKM------IKLIKREINNLQKLD---SKY--IVKLYDVSRTP--NNLYMFLEYCM
 ..|..||||.|| .|..|......  |..||.|.|..|..... ..      ..|.|.||....||.   ...  ||||||...|.  ||.|...||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

DGDLKEYLKKKKG-------GMLSEPEAIKFFKHIVEGFKELQKHQIIHRDIKPANIMLSGG-------------RAKISDFGFSRQLEVDN---QAYMT
.|||..|.||.|.       . |||.|||.|||.|..|||||.||.||||||||.||... |             ..||.||||..... .|   | ..|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

LL------GSPLYMSPQILE----GTKFS-SKCDVWSVGLVFYEMLYGKTP---WMGTSQI----NLFNN-------IKEKPLVFP---SDPVRSDKVKS
..      |.||||.||||.    . ... .|||.||.| .||||||||.|   |  ..|.    .| ||       || .|. ||   .||..|...|.
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIKRMLQFREEDRISWQEVFDDELI
||.||||. |.|||||.|.|. ...
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 3032.AA ULK 16-273 40 5.3e-141 474.73 In-house 1-329 (329) Show / Hide 
Range on Protein: 16-273
Range on HMM: 1-329/329
Sequence Identity: 40% (132 aa)

VVVNKKLGKGAFGTVFRGFCEDDE---NKLVAAKQIPIKNISNSDKM------IKLIKREINNLQKLD----SKY----IVKLYDVSRTP--NNLYMFLE
 ..|..||||.||.|..|......   |..||.|.|... .... ..      ..|.|.|| ...||.    .|.    ||||||...|.  ||.|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCMDGDLKEYLKKKKG--------GMLSEPEAIKFFKHIVEGFKELQKHQIIHRDIKPANIMLSGG-------------RAKISDFGFSRQLEVD---NQ
|| .|||..|.||.|.        . |||.|||.|||.|..|||||.||.||||||||.||... |             ..||.||||..... |   .|
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

AYMTLL------GSPLYMSPQILE----GTKFS-SKCDVWSVGLVFYEMLYGKTP---WMGTSQI-----NLFNN-------IKEKPLVFP---SDPVRS
 .|| .      |.||||.||||.    . ... .|||.||.| .||||||||.|   |  ..|.     .|.||       || .|| ||   .||..|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

DKVKSLIKRMLQFREEDRISWQEVFDDELI
...|.||.||||. |.|||||.|.|. ...
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 3032.AA S_TKc 16-273 32 9.2e-84 285.5 SMART 1-231 (231) Show / Hide 
Range on Protein: 16-273
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

VVVNKKLGKGAFGTVFRGFCEDDENKLVAAKQIPIKNISNSDKMIKLIKREINNLQKLDSKYIVKLYDVSRTPNNLYMFLEYCMD--GDLKEYLKKKKGG
  . .|.||||||.|...   .  ...|| |.|.           . |.|||. |.| . ..||||||| .. ..|||..|||    |||..|.||....
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

M----LSEPEAIKFFKHIVEGFKELQKHQIIHRDIKPANIMLSGGRAKISDFGFSRQLEVDNQAYMTLLGSPLYMSPQILEGTKFSS-KCDVWSVGLVFY
     ..| .| .... |... . . .|.|||||.||.||.|.  . ||.|||..|||       .|. |.| ||.| .|   ...  |||.||.| ..|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EMLYGKTPWMGTSQINLFNNIKEKPLVFPSDPVRSDKVKSLIKRMLQFREEDRISWQEVFD-------DELI
|||.|..|.    .  .|..|.            |. .|..|...||.  |.|..  |..        .. .
EMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 3032.AA Ciliate-E2c 19-273 33 1.9e-82 280.21 In-house 4-310 (310) Show / Hide 
Range on Protein: 19-273
Range on HMM: 4-310/310
Sequence Identity: 33% (104 aa)

NKKLGKGAFGTVFRG-FCEDDENKLV--------AAKQIPIKNI---SNSDKMIK-LIKREINNLQKLDSKYIVKLYDVSRTPNNLYMFLEYCMDGDLKE
|. ||.| .|.|...  |||. |           | | .. ||.    ...| ||  |.||||.. ......|.| ||   | ...| ..||| .|.|. 
NNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGTLEQ

YLKKK-KGGMLSEPEAIKFFKHIVEGFKELQKH-QIIHRDIKPANIMLSGGRAKISDFGFSRQLEVDNQAYMT----LLGSPLYMSPQILEG-TKFSSKC
|...| |   ..| . .  |. |. .||.| |   |.||||||.|| .  |  || |||||..   ||  . .      |.|.||.||||||  .  .| 
YIYHKPK---PNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGKNYYTEKS

DVWSVGLVFYEMLYGKTPWM------------------GTSQINLFNNIK---------------EKPLVFPSD--PVRSDKVKSLIKRMLQFREEDRIS
|.|| | . |.||. | ||                   ....  |. .|.                ... || .    .| .|| ||..|||. ||.||.
DIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEEKRID

WQEVFDDELI
| |.|..|.|
WDEIFNHECI
Kinase 3032.AA Pkinase 16-273 27 6.6e-81 279.89 Pfam 1-293 (293) Show / Hide 
Range on Protein: 16-273
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

VVVNKKLGKGAFGTVFRGFCEDDENKLVAAKQIPIKNISNSDKMIKL-IKREINNLQKLDSKYIVKLYDVSRTPNNLYMFLEYCMDG----DLKEYLK-K
 .. .|.|.|.||.|... .. ...|.|| |.|. .... . ..... . .||  ...|....||.|||. ......|| .|||. |    ||..|.. .
YHIGRKIGSGSFGCVYKC-HHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

KKGGM-LSEPEAIKFFKHIVEGFKELQKHQIIHRDIKPANIMLS-GGRA----KISDFGFSRQL-EVDNQAYMTLLGSPLYMSPQILE-GTKFSSKCDVW
..|.. .|| |...... |..| . . .. |||||.||.||...  |      ||.|||...|. .  |. ..|. |.| ||.| ..  |.. ..|.|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SVGLVFYEMLYGKTPWMGT------SQINLFNNIKEKPLVFPSDPVRS-------------------DKVKSLIKRMLQFREEDRISWQEVFDDELI
|.|...|||| |..|. |       .|. ....|...|| |...  .|                   .  |..||..|..  ..|....... .. .
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 3032.AA Ciliate-E2 16-273 25 3.2e-79 269.5 In-house 1-365 (365) Show / Hide 
Range on Protein: 16-273
Range on HMM: 1-365/365
Sequence Identity: 25% (95 aa)

VVVNKKLGKGAFGTVFRGFC-EDDENKL----------------VAAKQIPIKNISNSDKMIKL----IKREIN----------NLQKLDSKYIVKLYDV
  ..||.|.|.||.|...   ......                 |..|.. .|....... ...    | ||||          .|..|....|.|.|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

SR--TPNNLYMFLEYCMDGDLKEYLKKK----------KGGMLSEPEAIKFFKHIVE---------------GFKELQKHQ-IIHRDIKPANIMLSGGRA
    . ||.|. .|||  |||..|.|..          . . ..| |.....|.|..               ....| .   |||||||| ||..     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----I

KISDFGFSRQLEVDNQ-------------------------------AYMTLLGSPLYMSPQILEGTK---------FSSKCDVWSVGLVFYEMLYGKTP
||.|||.|...  |||                                . |..|.| ||.|.||.| |          . |||.||.| ..||||.||.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WMGTSQINLFNNIKEKPLVFP----------------SDPVRSDKVKSLIKR----MLQFREEDRIS-WQEVFDDELI
.        ...||.... ||                |    |...| |||.    |||  .| ||. |..... . .
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 3032.AA CAMK 21-273 21 4.3e-78 251.07 In-house 1-425 (425) Show / Hide 
Range on Protein: 21-273
Range on HMM: 1-425/425
Sequence Identity: 21% (92 aa)

KLGKGAFGTVFRGFCEDDEN-----------KLVAAKQIPIKNISN------------------------SDKMIKLIKREINNLQK-------LDSKYI
.||.|.||.|....   . .           . ||.| |. | ...                        ..|. | ..|||. ..|       || . |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLYDVSR------------TPNN--------LYMFL---EYCMDG----DLKEYLKKKKG-------------GMLSEPEAIKFFKHIVEGFKELQKHQ
.|||.|              | ..        .||..   |||  |    || .|......             | ..| || ..|. |... . . .| 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDIKPANIMLSG------------------GRAKISDFGFSRQLEV-----------------------DNQAYMTLLGSPLYMS-PQILEG-----
|.|||.|| ||.|.                   .  ||.||||.....                        ..| . |  |.| ||. | .|.|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------TKFSSKCDVWSVGLVFYEMLYGKTPWMGT-------------SQINLFNNIKEKPLVFPSDPV--------------RSDK--------VK
         .  . |||.||.| . | || |. |. |              .. .|| .|..    ||....               ||         .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

SLIKRMLQFREEDRISWQEVFDDELI
.||..|||   |.|.. ... ... .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 3032.AA AGC 16-267 21 1.2e-72 186.28 In-house 1-389 (395) Show / Hide 
Range on Protein: 16-267
Range on HMM: 1-389/395
Sequence Identity: 21% (86 aa)

VVVNKKLGKGAFGTVFRGFCED-----DENKLVAAKQIPIKN-ISNSDK-MIKLIKRE------------INNLQKLD----------SKYIVK-LYDVS
  . | .|||.||.|.     |     | .|. | | .  |  |   .| |.. ...|             | |.|..          . .||| |.   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

RTPNN--LYMFLEYCM----------DGDLKEYLKKK-KGGMLSEPEAIKFFK-------HIVEGFKELQK-HQIIHRD-IKPANIMLSG-GRAKISDFG
 ....  ||. .||.           ...|  .|... | | ..|..|  ..        .|| ..  | . . ||||| .|| ||.|   |  |..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FSRQLEVDN--------------------------------------------------QAYMTLLG--SPLYMSPQILEGTKFSSKCDVWS--VGLVFY
.. ..  |.                                                  .   |. |  .| ||.| ||     .  || ||  .| ..|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLYGKTPWMGTS----------QINLFNNIK------EKPLVFPSD--------PVRSDKVKSLIKRMLQFREEDRIS----------WQEV
|||.|..|  | .          .  .|..|.      .... ||..        .  |.  |.|||..|.   |.|.            .|.
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEI
Kinase 3032.AA Ciliate-E2-Unclassified 17-273 25 8.9e-72 244.77 In-house 2-352 (352) Show / Hide 
Range on Protein: 17-273
Range on HMM: 2-352/352
Sequence Identity: 25% (89 aa)

VVNKKLGKGAFGTVFRGFCEDDENKLVAAKQIPIKNISNSDKMIKLIKREINNL-----------------------QKLDSKYIVKLYDVSRTPNNLYM
 ..|..|.|.||.|..  |.....|...|... .|......| |.  . ||.|                        . ... .|||.... .. .|.|.
KIIKQIGQGGFGKVYK--CQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

FLEYCMDGDLKEYLKKKKG---------------GMLSEPEAI-----KFFKHIVEGF-KELQKHQIIHRDIKPANIMLS-GG---RAKISDFGFSRQLE
 .||| .|||..|.||.|.                ...| .|.     ..|..|..|. .  .|. |||||||| ||... .|   . ||.|||.|....
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

VDNQA---------------YMTLLGSPLYM----SPQILEGTKFS----SKCDVWSVGLVFYEMLYGKTPWMGTSQIN----------------LFNNI
 .|.                . |  |.| ||    .| .|.| . .     |||.||.| ..||||.|. |  .....                 |..||
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KEKPLVFPSDP------VRSDKVKSLIK----RMLQFREEDRISWQEVFDDELI
|.|.. ||. |        |...| .|.    .||. . . ||......   ..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 3032.AA CAMKL 16-273 30 1.8e-66 211.12 In-house 1-297 (297) Show / Hide 
Range on Protein: 16-273
Range on HMM: 1-297/297
Sequence Identity: 30% (92 aa)

VVVNKKLGKGAFGTVFRGFCEDDENKLVAAKQIPIKNISNSDKMIKL-----------IKREINNLQKLD---SKYIVKLYDVSRTPNN------LYMFL
  . | ||||.||.|  .  .   .. || | | .| |.| ..| |            |.|||. ...|.    . |.|||.|  ||..      .|...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCMDGD--LKEYLKKKKG--GMLSEPEAIKFFKHIVEGFKELQKHQIIHRDIKPANIMLSGGR---AKISDFGFSRQLE-V---DNQAYMTLLGSPLYM
|||  |.  | .|..|...  | ..|.|| ..|. ||.. . . .| |.|||||| ||.|.      .||.||||| . . .   ..|  .|  ||| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPQILEG--TKFS-SKCDVWSVGLVFYEMLYGKTPWMGT--------SQINLFNNIKEKPLVFPSDPVRSDKVKSLIKRMLQFREEDRISWQEVFDDELI
.| |..|  ...   | |.|| | . | |..|. |. .          . .|.. |..    .|  .  |  ...||..|||   |.|.. ...  ..  
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 3032.AA STE 17-273 22 1.8e-57 197.28 In-house 1-359 (359) Show / Hide 
Range on Protein: 17-273
Range on HMM: 1-359/359
Sequence Identity: 22% (82 aa)

VVN-KKLGKGAFGTVFRGFCED-----DENKL---------VAAKQIPIKNISNSDKM--------------IKLIKREINNLQKLD--SKYIVKLYDVS
  . .|.||||||||... . .     . ...         .| ||....| .|.|                .. |..||. ..|..  ...||| |.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

RTP-------NNLYMFLEYCMDGDLKEYLK-K-KKGGMLS----------EPEAIKFFKHIVEG-FKELQKHQIIHRDIKPANIMLSGGRAKISDFGFSR
          ..|....||.  | | . .| | ..|..|.          |.. ... . |..|  . | .|.|||||||||||.|    .|..|||.. 
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCG

QLEVD--------------NQAYM--TLLGSPLYMSPQILEG------TKFSSKCDVWSVGLVFYEMLYGKTPWMGTSQI-NLFNNIKE-----------
||. .              ... .  |. |.| .|.| ....       . . |||.||.|..  ||. || ||.  .   ..|. ...           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----KPLVFPSD-----------------PVRSDKVKSLIKRMLQFREEDRISWQEVFD--DELI
    .|  .|..                    |.. |  |.. ||   ..| . ..      . |
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 3032.AA STE11 16-273 27 1.2e-49 171.28 In-house 1-303 (303) Show / Hide 
Range on Protein: 16-273
Range on HMM: 1-303/303
Sequence Identity: 27% (85 aa)

VVVNKKLGKGAFGTVFRGFCEDDENKLVAAKQIPIKNISNS----------DKMIKLIKREINNLQKLDSKYIVKLYDVSR---TPNNLYMFLEYCMDGD
    ...||||||||....   | ..|.| |||.|.|...            ||.|.|. ||. ...|. | ||. |....     .... |.|||  | 
WQKGEIIGKGAFGTVYKCM-NVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGS

LKEYLKKKKGGM-LSEPEAIKFFKHIVEGFKELQKHQIIHRDIKPANIMLSG-GR-AKISDFGFSRQLEVDN---------QAYM--TLLGSPL------
|.. |. | | | ..|..  |. | | || . | .|.|||||||.|||.|   |   |..||| ...|. ..         |. .  .. |.|       
LSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQN-HCKSMTGTPYNSMMGT

--YMSPQILEGTK---FSSKCDVWSVGLVFYEMLYGKTPWMGT---SQINLFNNIKE-K-PLVFPSD--P--VRSDKVKSLIKRMLQFREEDRISWQEVF
  .|.| .. ...    . |.|.||.| . .||. || || .    .. ..|  ..  | .  .|..  |  . |.. .  ... ...  ..| . .. .
PMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLL

DDELI
..  |
QHPFI
Kinase 3032.AA Pkinase_Tyr 16-231 26 6.1e-29 98.63 Pfam 1-231 (270) Show / Hide 
Range on Protein: 16-231
Range on HMM: 1-231/270
Sequence Identity: 26% (63 aa)

VVVNKKLGKGAFGTVFRGFCE---DDENKLVAAKQIPIKNISNSDK--MIKLIKREINNLQKL-DSKYIVKLYDVSR-TPNN--LYMFLEYCMDGDLKEY
.. .||||.||||.|..| .    |...  || | .  |. . ..   . .... |.. . .| . . ||.|| |         .|. .||.  |||..|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LKKK--KGGMLSEPEAIKFFKHIVEGFKELQKHQIIHRDIKPANIMLS-GGRAKISDFGFSRQLEVDNQA-YMTL--LGSPLYMSPQILEGTKFSSKCDV
|.|.   .. |. .. ...   | .|   |  ...||||.   |.... .. .||.||| .| .. | .  ...         |.|  .   ||..| ||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

WSVGLVFYEMLY-GKTP-WMGTSQINLFNNI-KE
|| | . .|..  |..| . | |   ... | ..
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED
Kinase 3032.AA TyrKc 16-280 25 8.1e-27 96.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 16-280
Range on HMM: 1-280/280
Sequence Identity: 25% (76 aa)

VVVNKKLGKGAFGTVFRGFCEDDENKLVAAKQIPIKNISNSDKMIKLIKREINNLQKL--DSKYIVKLYDVSRTP-------NNLYMFLEYCMDGDLKEY
.. .|||| ||||.|..|         || | .           .. . ||.. . ||  . . ||.|| | ...         |.. .||.  ||||.|
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LKKKKGGMLSEPEAIKFFKHIVEGFKELQKHQIIHRDIKPANIMLSGGR-AKISDFGFSRQLEVD------NQAYMT----LLG--SPL-YMSPQILEGT
|.|...  |. .. ..|   | .|   | ....||||.   |.... .. .|||||| || .. |       . |..          |.  |.|  .   
LRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

KFSSKCDVWSVGLVFYEML-YGKTPWMG-----TSQINLFNNIKEKPLVFPSDPV-------RSDKVKSLIKRMLQFREEDRISWQEVFDDELITGDRKL
||..| |||| | . .|.. ||..|. |      | . .....|.     . . .        .|.. ...|.  ..  ||| . .|.         ...
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---------HEC

L
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