Gene 4111 (Tetrahymena)
4111
Sequence
Protein domains of 4111.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 4111.AA | ULK | 13-270 | 39 | 3.2e-134 | 452.19 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 13-270 Range on HMM: 1-324/324 Sequence Identity: 39% (128 aa) ILVNHKLGRGSYG-TVYRGYLEQDE--NQMIAAKQIPIKEICSSTSR------IQYIKREIENLQKID---SKY--VVKLFGVSRTQ--TNLYMFLEYCV . .||.|| ||.| .||.|. .... || .|.|.|..|.. . .. .| .|.||....|.. ... .|||. ...|. .|.|...||| YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN DGDLKSYLKKK-------ENKILSEPEAIKIFKHIVEGFKELNKYKIIHRDIKPANLLISNGI-------------VKLADFGFSKVVE---DEEARLRS .|||..|.||. |.|.|||.|||..||.|..|||||.| .||||||||.|.||.||. .|.|||||.|.|. |. . . GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT FI------GSPLYMAPELQE----QMPFS-SKCDVWSTGIVLYEMLYGKTP---WNGSSQL----NLFEN-------IKNQPLVFP---DEPIRSNKLKS . |.||||||.... |.|.. .|||.|| |...|||||||.| | ..| .| .| |||||. || ..|..|...|. CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD LIKKMLQYYEKDRISWSEIFDDDLI ||..|||| ||||||| |||. .. LIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | 4111.AA | ULK | 13-270 | 37 | 5.3e-132 | 444.82 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 13-270 Range on HMM: 1-329/329 Sequence Identity: 37% (125 aa) ILVNHKLGRGSYGTVYRGYLEQDE---NQMIAAKQIPIKEICSSTSR------IQYIKREIENLQKID----SKY----VVKLFGVSRTQ--TNLYMFLE . .||.|| ||.|.||.|. .... |...|.|.|..... . .| .|.||....|.. .|. .|||. ...|. .|.|...| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME YCVDGDLKSYLKKK--------ENKILSEPEAIKIFKHIVEGFKELNKYKIIHRDIKPANLLISNGI-------------VKLADFGFSKVVEDE---EA || .|||..|.||. |.|.|||.|||..||.|..|||||.| .||||||||.| ||.||. .|.|||||.|.|... .. YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ RLRSFI------GSPLYMAPELQE----QMPFS-SKCDVWSTGIVLYEMLYGKTP---WNGSSQL-----NLFEN-------IKNQPLVFP---DEPIRS . .. |.||||||.. . |.|.. .|||.|| |...|||||||.| | ..| .|..| ||.||| || ..|..| MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS NKLKSLIKKMLQYYEKDRISWSEIFDDDLI ...|.||..|||| ||||||| |.|. .. PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | 4111.AA | S_TKc | 13-270 | 28 | 2.9e-82 | 280.54 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 13-270 Range on HMM: 1-231/231 Sequence Identity: 28% (78 aa) ILVNHKLGRGSYGTVYRGYLEQDENQMIAAKQIPIKEICSSTSRIQYIKREIENLQKIDSKYVVKLFGVSRTQTNLYMFLEYCVD--GDLKSYLKKKEN- . |.|.|..|.||... .. | |.|. . |.|||. |.| . ...|||..| .. ..|||..||| |||..|.||. YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH ---KILSEPEAIKIFKHIVEGFKELNKYKIIHRDIKPANLLISNGIVKLADFGFSKVVEDEEARLRSFIGSPLYMAPELQEQMPFSS-KCDVWSTGIVLY . ..| .| .... |... . . . .|||||.||.|.|... .|..|||..... ..|.|.| |||||. ... |||.|| |..|| GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY EMLYGKTPWNGSSQLNLFENIKNQPLVFPDEPIRSNKLKSLIKKMLQYYEKDRISWSEIFD-------DDLI |||.|..|. . .|..|. | .|..|.|.||. ..|.. |.. . . EMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 4111.AA | Ciliate-E2c | 13-270 | 31 | 1.2e-79 | 270.92 | In-house | 1-310 (310) | Show / Hide |
Range on Protein: 13-270 Range on HMM: 1-310/310 Sequence Identity: 31% (98 aa) ILVNHKLGRGSYGTVYRGYLEQDENQMIAA---------KQIPIKEI---CSSTSRIQ-YIKREIENLQKIDSKYVVKLFGVSRTQTNLYMFLEYCVDGD | | || ||||.||..|. |.. |. | .. |.. . . | |.|||... . ......| | ..| ..||| .|. IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT LKSYLKKK-ENKILSEPEAIKIFKHIVEGFKELNKY-KIIHRDIKPANLLISNGIVKLADFGFSKVVEDEEARLRS----FIGSPLYMAPELQEQ-MPFS |..|...| . ..| . . |. |. .||.| | .|.||||||.| || ||..|.||||||| . |.. . |.|.||||. | LEQYIYHKPK---PNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGKNYYT SKCDVWSTGIVLYEMLYGKTPWN------------------GSSQLNLFENIK---------------NQPLVFPDE--PIRSNKLKSLIKKMLQYYEKD .| |.|| |..||.||. | || .... |...|. .|.. ||.. .| ..| ||.||||. |.. EKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEEK RISWSEIFDDDLI ||.|.|||.. .| RIDWDEIFNHECI |
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Kinase | 4111.AA | Pkinase | 13-270 | 26 | 1.2e-73 | 255.83 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 13-270 Range on HMM: 1-293/293 Sequence Identity: 26% (80 aa) ILVNHKLGRGSYGTVYRGYLEQDENQMIAAKQIPIKEICSSTSRIQYIK-REIENLQKIDSKYVVKLFGVSRTQTNLYMFLEYCVDG----DLKSYLKKK . . |.|.||.|.||... ....... | |.|. ... .| ... .. .||. .........|.|... .. ...|| .||| | ||..|.. . YHIGRKIGSGSFGCVYKCH-HKGTGKIVAVKIIKKRHE-KSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW ENKIL--SEPEAIKIFKHIVEGFKELNKYKIIHRDIKPANLLIS-NGIV----KLADFGFSKVV-EDEEARLRSFIGSPLYMAPEL-QEQMPFSSKCDVW ... . || |...... |..| . . . .|||||.||.|.||. || . |..|||..|.. . . .| |.| |||||. ... . ..|.|.| RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW STGIVLYEMLYGKTPWNGS------SQLNLFENIKNQPLVFPDEPIRS-------------------NKLKSLIKKMLQYYEKDRISWSEIFDDDLI | |..||||| |..|. |. .|. ....|. || |. . .| .|..||..|.. |.|... .|. .. . SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 4111.AA | Ciliate-E2 | 13-270 | 23 | 2.1e-73 | 250.19 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 13-270 Range on HMM: 1-365/365 Sequence Identity: 23% (89 aa) ILVNHKLGRGSYGTVYRG--YLEQDENQMI---------------AAKQIPIKEICSS----TSRIQYIKREIE----------NLQKIDSKYVVKLFGV . .. |.|.|..|.||.. ...| . ... ..|.. .| . . ......| |||. .|.........|.. . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC SR--TQTNLYMFLEYCVDGDLKSYLK---KKENKI------LSEPEAIKIFKHIVE---------------GFKELNKYK-IIHRDIKPANLLISNGIVK ...|.|. .||| |||..|.| ||.|.. ..| |...|.|.|.. ....| . . |||||||| |.|. .| FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK LADFGFSKVVEDE-------------------------------EARLRSFIGSPLYMAPELQEQMP---------FSSKCDVWSTGIVLYEMLYGKTPW ..|||.|| . |. . ....|.| ||||| . . . |||.|| |..|||||.||.|. IIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF NGSSQLNLFENIKNQPLVFP----------------DEPIRSNKLKSLIKK----MLQYYEKDRIS-WSEIFDDDLI ...||.... || . |.. | |||| |||. .. ||. |..|.. . --------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 4111.AA | CAMK | 18-270 | 20 | 1.2e-71 | 229.94 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 18-270 Range on HMM: 1-425/425 Sequence Identity: 20% (86 aa) KLGRGSYGTVYRGYLEQDEN-----------QMIAAKQIPIKEICS------------------------STSRIQYIKREIENLQK-------IDSKYV .|||||.|.|.... .. . | |.| |. | . . . . . ..|||| ..| .| . . TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI VKLFGVSR------------TQTN--------LYMFL---EYCVDG----DLKSYLKKKEN-------------KILSEPEAIKIFKHIVEGFKELNKYK .||. | | .. .||.. ||| | || .|...... . ..| || ..|. |... . . . . IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN IIHRDIKPANLLI-SN-----------------GIVKLADFGFSKVVED-----------------------EEARLRSFIGSPLYMA-PELQEQ----- |.|||.|| |.|. .| . .|..||||...... | .. | |.| ||| ||. .. IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN ---------MPFSSKCDVWSTGIVLYEMLYGKTPWNGS-------------SQLNLFENIKNQPLVFPDEPIRS----------------------NKLK . . |||.|| |..|| || |. |..|. .. .|||.|.. ||.... | MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK SLIKKMLQYYEKDRISWSEIFDDDLI .||.||||. ..|.. ... .. . DLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | 4111.AA | CAMKL | 12-270 | 27 | 2.6e-68 | 217.08 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 12-270 Range on HMM: 1-297/297 Sequence Identity: 27% (84 aa) YILVNHKLGRGSYGTVYRGYLEQDENQMIAAKQIPIKEICSSTSRIQY-----------IKREIENLQKID---SKYVVKLFGVSRTQTN------LYMF |... ||.||.|.| . .. ... | | | .| |. . . |.|||. ..... . ..||. | |... .|.. YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV LEYCVDGD--LKSYLKKKENKI--LSEPEAIKIFKHIVEGFKELNKYKIIHRDIKPANLLIS-NG--IVKLADFGFSKVVED----EEARLRSFIGSPLY .||| |. | |..|.... ..|.|| ..|. ||.. . . . .|.|||||| |.|.. || .|..||||| .. .. |. | ||| | MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY MAPELQEQ--MPFS-SKCDVWSTGIVLYEMLYGKTPWNGS--------SQLNLFENIKNQPLVFPDEPIRSNKLKSLIKKMLQYYEKDRISWSEIFDDDL ||||. . |. | |.|| |..|| |..|. |... . .|.. |. . .| . | ...||.|||| ..|.. .| . MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW I M |
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Kinase | 4111.AA | AGC | 13-264 | 20 | 3.2e-68 | 174.55 | In-house | 1-389 (395) | Show / Hide |
Range on Protein: 13-264 Range on HMM: 1-389/395 Sequence Identity: 20% (79 aa) ILVNHKLGRGSYGTVYRGYLEQ-----DENQMIAAKQIPI--KEICSSTSRIQYIKRE------------IENLQKID----------SKYVVK-LFGVS . .|.||.|.|| | ... | | . | .. ......| . |.|.. . ..|| |. FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF RTQTN--LYMFLEYCV----------DGDLKSYLKKK-ENKILSEPEAIKIFK-------HIVEGFKELNK-YKIIHRD-IKPANLLISN-GIVKLADFG .... ||. .||. ...| ..|... .....|..| .. .|| .. | . .||||| .|| |.|. . | .||.||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG FSKVVEDEE--------------------------------------------------ARLRSFIG--SPLYMAPELQEQMPFSSKCDVWS--TGIVLY ..|.. ... .| .| | .| ||||| . || || |...| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EMLYGKTPWNGSS----------QLNLFENIK------NQPLVFP--------DEPIRSNKLKSLIKKMLQYYEKDRIS----------WSEI |||.|..| .| . . .|..|. |... || ... |. .|.||||.|. ..|. .|| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEI |
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Kinase | 4111.AA | Ciliate-E2-Unclassified | 13-270 | 24 | 2.9e-66 | 226.45 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 13-270 Range on HMM: 1-352/352 Sequence Identity: 24% (88 aa) ILVNHKLGRGSYGTVYRGYLEQDENQMIAAKQIPIKEICS------STSRIQYIKREIENLQ----------------KIDSKYVVKLFGVSRTQTNLYM .....|.|..|.||. . ... | | |.. . |.. . .| .. |..|.. ... ..||.| . ... |.|. YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI FLEYCVDGDLKSYLKKKEN---------------KILSEPEAI-----KIFKHIVEGFKELNKYK-IIHRDIKPANLLISNG----IVKLADFGFSKVVE .||| .|||. |.||... ||..| .|. ..|..|..|.. | . . |||||||| |.|..|. .|..|||.|| . VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ DE---------------EARLRSFIGSPLYM----APELQEQMPFS----SKCDVWSTGIVLYEMLYGKTPWNGSSQLN----------------LFENI . . .. .|.|.| || |||. .. . |||.|| |..|||||.|. | .. .. |..|| QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI KNQPLVFPDEP------IRSNKLKSLIK----KMLQYYEKDRISWSEIFDDDLI |.... || .| . |.. | .|. |||.. . ||....|. .. KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 4111.AA | STE | 14-270 | 23 | 1.4e-56 | 194.33 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 14-270 Range on HMM: 1-359/359 Sequence Identity: 23% (84 aa) LVN-HKLGRGSYGTVYRGYLEQ-----DENQM---------IAAKQIPIKEIC-------------SSTSRIQYIKREIENLQKID--SKYVVKLFGVSR . . |.|.|..||||... . .. .| ||..... . .. .| |..||. ..| . ....|| .| WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF TQ-------TNLYMFLEYCVDGDLKSYLK-K-KENKILS----------EPEAIKIFKHIVEG-FKELNKYKIIHRDIKPANLLISNGIVKLADFGFSKV ..|....||. | | . .| | . .| |. |.. ..| . |..| . | . .|||||||||| |. |||.|||... KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ VED---------------EEA-RLRSFIGSPLYMAPELQEQM------PFSSKCDVWSTGIVLYEMLYGKTPWNGSSQL-NLFENIKN------------ ..| . . .|.|.| .|||| .|. . . |||.|| |... ||. || || . . ..|. ..| LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCI ---QPLVFPD-----------------EPIRSNKLKSLIKKMLQYYEKDRISWSEIFD--DDLI .| .|| | ..| |.| ||. ..| . |. | VNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | 4111.AA | CAMKK | 12-270 | 22 | 6.9e-53 | 165.96 | In-house | 1-396 (396) | Show / Hide |
Range on Protein: 12-270 Range on HMM: 1-396/396 Sequence Identity: 22% (89 aa) YILVNHKLGRGSYGTVYRGYLEQDE---------NQ----MIAAKQIPIK-------------EICSSTSRIQYIKREIENLQKIDSKYVVKLFGV--SR | |. ..|.|..| | . | | |. | . |.. . . ..... ...||. . |.. ...|||. | .. YELM-KEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDP TQTNLYMF-LEYCVDGDLKSYLKKKE-----------------------NKILSEPE---------------------AIKIFKHIVEGFKELN-KYK-- .....|| .||| |.... ..|. .|.||.. | |.| ... | . | . | QNDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKAC -----------------IIHRDIKPANLLI-SNG---IVKLADFGFSKVVEDEEARLRS-----------FIGSPLYMAPELQEQ-MPFS---------- |||||||| |.|| ..| ||.|||| |. .|.....| . | | .|||||.. .. SYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFR -----SKCDVWSTGIVLYEMLYGKTPWNGSSQLNLFE---NIKNQPLVFPD-----------EPIRSNKLKSLIKKMLQYYEKDRISWSEIFDDDLI ..|.|..|. || ...||.| .. . . |.. |||.|..||. .| |. ||.|||.||. ...||. ..| .. . FIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV |
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Kinase | 4111.AA | Pkinase_Tyr | 13-214 | 28 | 1.5e-30 | 104.1 | Pfam | 1-216 (270) | Show / Hide |
Range on Protein: 13-214 Range on HMM: 1-216/270 Sequence Identity: 28% (62 aa) ILVNHKLGRGSYGTVYRGYLE---QDENQMIAAKQIPIKEICSSTS-RIQYIKREIENLQKI-DSKYVVKLFGVSR-TQTN--LYMFLEYCVDGDLKSYL | ..|||.|..|.||.|.. ..... | | . || ... .. ||.. . .. . . .|.| || . .|. .||. |||..|| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL KKK--ENKILSEPEAIKIFKHIVEGFKELNKYKIIHRDIKPANLLIS-NGIVKLADFGFSKVV-EDEEA-RLRSFIGSPL-YMAPE-LQEQMPFSSKCDV .|. ... |. .. ... | .| | ..||||. | |.. |..|| .||| .. . .|.. | |. | |||| ... |..| || RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDV WSTGIVLYEMLY-GKTP-W || |....|.. |..| . WSFGVLMWEIFTYGEQPTY |
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Kinase | 4111.AA | TyrKc | 13-269 | 25 | 5.7e-20 | 73.58 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 13-269 Range on HMM: 1-280/280 Sequence Identity: 25% (76 aa) ILVNHKLGRGSYGTVYRGYLEQDENQMIAAKQIPIKEICSSTSRIQYIKREIENLQKI--DSKYVVKLFGVSRTQ-------TNLYMFLEYCVDGDLKSY | ..|||.| .|.||.| . .. | | . .. . ||.. . |. . . .|.|.|| ..| |.. .||. ||||.| ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY LKKKENKILSEPEAIKIFKHIVEGFKELNKYKIIHRDIKPANLLISNG-IVKLADFGFSKVVEDE--------EARLRSFIGSP--L---YMAPELQEQM |.|...| |. .. ... | .| | . ..||||. | |.... .|| .||| |. ..|. | .. |. | |||| LRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG PFSSKCDVWSTGIVLYEML-YGKTPWNG-----SSQLNLFENIKNQ-PLVFPDE------PIRSNKLKSLIKKMLQYYEKDRISWSEIFDDDL |..| |||| |....|.. ||..|. | | ..|..|. . |.. .. . .. ...|. .. .|| . ||| ... KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |