Gene 26815 (Tetrahymena)

26815

Species: Tetrahymena
Alias: 3702.m00234, 485, 26815, PreTt26815, 11.m00512, TTHERM_00146080
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: WEE

Sequence

Name Sequence Type Origin Length Description Download
26815.AA Protein None 674 None Fasta, JSON
26815.kin_dom Protein Kinase Domain None 262 None Fasta, JSON
26815.NA RNA None 2025 None Fasta, JSON

Protein domain

Protein domains of 26815.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26815.AA WEE 364-625 39 2.1e-151 509.29 In-house 1-297 (297) Show / Hide 
Range on Protein: 364-625
Range on HMM: 1-297/297
Sequence Identity: 39% (117 aa)

YEVLQVLGSGFFGTVYKCQNRIDKNIYAVKVTKEQIRGENSQKQILKEAQALASLS---ACDEVEYIVCYHSAWIEDRQLHLAMEFCDS--NLANFPLPQ
....|..|.|.||.||||..|||..|||.|..| ..||....|..|.|..|...|.   .||....||.|.|||.||......||.|..  ||..|...|
FQEVQKIGEGSFGEVYKCRCRIDGCIYAIKKSKQPFRGYSERKRALREVYAHMVLGQIMDCDHHPHIVRYYSAWEEDDHMYIQMEYCNGGSNLLQFWIQQ

PPNYNQ--FYQMIKKIFQDVVKGLHYLHQQ-NLVHLDLKPENILYNKKQ-------------------NKFKIADLGLALIANKDNEKYNQIEEGDARYL
..|.|.  ...||..|..|...|||..|.. ..||.|.|||||...||.                   ...||.|.|.. ..|..|....|..|||.||.
CHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVTDMNSNNNNPHQEQEGDSRYM

AKEILN-YYEAVDLKKADIFSLGAMMYHLVTQEQLPTNGDEWLQIRQG-------HLPNLDSLNQCPKELKQMIRQMMNPDPELRLSTQEILDSSYM
|.|||. ||....|.||||||||...|.|.....||.|||.| |||||       ..|.....|....||||.|..||.||||.| ..|..|.....
APEILQGYYHYTHLYKADIFSLGITIYELACNMDLPKNGDWWHQIRQGDLSFDKNQIPFPEFDNIISQELKQLIKWMMHPDPEQRPTCQQLLQHPVL
Kinase 26815.AA Pkinase 364-625 21 4.3e-47 167.58 Pfam 1-293 (293) Show / Hide 
Range on Protein: 364-625
Range on HMM: 1-293/293
Sequence Identity: 21% (66 aa)

YEVLQVLGSGFFGTVYKCQNRIDKNIYAVKVTKEQIRGENSQKQILK--EAQALASLSACDEVEYIVCYHSAWIEDRQLHLAMEFCDS-----NLA----
|......||| ||.||||... .  |.|||. | . . .. ... ..  |.| ...|.     ..|| .. .. ... ... ||.|.       |.    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN----HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

NFPLPQPPNYNQF---YQMIKKIFQDVVKGLHYLHQQNLVHLDLKPENILYNKKQNK---FKIADLGLALIA-NKDNEKYNQIEEGDARYLAKEILNYYE
        ... |   .. .|...  ...|| |.|... .| ||||||||.... .    .||.| |||  . .  |.  ..   |  .|.| |...   
T------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIR-GG

AVDLKKADIFSLGAMMYHLVTQEQLPTNG--------DEWLQIRQGHLPNLDSLNQCP-------------------KELKQMIRQMMNPDPELRLSTQE
  . .|.|..|.| ..| ... . .  .         .. .. . |  .  |. . |.                   .|.|. |. . ..||. |.. ..
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ

ILDSSYM
|| . ..
ILQHPWF
Kinase 26815.AA S_TKc 364-625 24 1.3e-43 152.16 SMART 1-231 (231) Show / Hide 
Range on Protein: 364-625
Range on HMM: 1-231/231
Sequence Identity: 24% (66 aa)

YEVLQVLGSGFFGTVYKCQNRIDKNIYAVKVTKEQIRGENSQKQILKEAQALASLSACDEVEYIVCYHSAWIEDRQLHLAMEFCDS---NLANFPLPQPP
||.|...|.| ||.||||... .. |.|.|. |         ..|..| | | .       ..|| .. .. .   |.. ||.||    .|  .   ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

NYN---QFYQMIKKIFQDVVKGLHYLHQQNLVHLDLKPENILYNKKQNKFKIADLGLALIANKDNEKYNQIEEGDARYLAKEILNYYEAVDLKKADIFSL
. .       ....... ....| |.|... .| |||||||| ..     ||.| ||| .             |   |.| |.|      . .|.|. |.
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDWWSC

GAMMYHLVTQEQLPTNGDEWLQIRQGHLPNLDSLNQCPKELKQMIRQMMNPDPELRLSTQEILD-------SSYM
| ..| ...  . |   .. . ...            ..|.|..||.... ||| |..  |.|          ..
GCILYEMLC-GYPPFP-QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 26815.AA Ciliate-E2 364-625 19 1.2e-39 133.75 In-house 1-365 (365) Show / Hide 
Range on Protein: 364-625
Range on HMM: 1-365/365
Sequence Identity: 19% (76 aa)

YEVLQVLGSGFFGTVYKCQNRIDKN-----------------------IYAVKVT-KEQIRGENSQKQIL----------KEAQALASLSACDEVEYIVC
|......|.| ||.||||... ...                       |||.|.  | ||.  .. ..|.          .| . | .|.      .|. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLN----HPNIIK

YHSAWI--EDRQLHLAMEFCDSN-----LANFPLP-------QPPNYNQFYQMIKKIFQDVVK---------------GLHYLHQQN-LVHLDLKPENIL
.. ...   |  . | ||.|. .     . |...        .  ...   . ||.|.. ...               .|.|||..|  .| |.||||||
MYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTE--KEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENIL

YNKKQNKFKIADLGLALIANKDNEK-------YNQIEEG------------------------DARYLAKEILN---YY----EAVDLKKADIFSLGAMM
.       ||.|.||. ....||..       .. .. .                         . |.| ||||   |.    .    .|.||.||| ..
F------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

YHLVTQEQLPTNGDEWLQIRQGHLPNLD----------------SLNQCPKELKQMIRQ----MMNPDPELRLS-TQEILDSSYM
| ... .         .|. .    ...                | .....| |..|..    |.. ||| |..  ..||.  ..
YEMLFGKPPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 26815.AA TKL 370-623 18 5.1e-35 122.67 In-house 1-364 (364) Show / Hide 
Range on Protein: 370-623
Range on HMM: 1-364/364
Sequence Identity: 18% (70 aa)

LGSGFFGTVYKCQNRIDK--------NIYAVKVTKE---QIRGENSQ----------------------KQILKEAQALASLSACDEVEYIVCYHSAWI-
.|||.||.||| . |           .  |||. |.   . . .|||                      ... .|.  . .|.    | .. .  .    
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

--------EDRQLHLAMEFC-DSNLANFPLPQPPNYNQFYQMIKKIFQDVVKGLHYLHQQN--------LVHLDLKPENILYNK-------------KQN
        .. ||.. ||.|   .| .. .          . . .. .|. .|..|||..|        ..| |||..||| ..             .. 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

KFKIADLGLALIANKDNEKYNQI------------------EEGDARYLAKEILN----YYEAV----------DLKKADIFSLGAMMYHLVTQEQLPTN
. ||.|.||.   ......  .                   . |  |..| |.|.    | |.|            .|.|..| | ... ..| ..   .
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

GDE-------------WLQIRQGHLPNLD----------SLNQCPKELKQMIRQMMNPDPELRLSTQEILDSS
 ..             .. .  |. | ..            ..||...|. . . ...||| |.| ||||.  
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 26815.AA Ciliate-E2-Unclassified 364-625 20 3.1e-34 116.15 In-house 1-352 (352) Show / Hide 
Range on Protein: 364-625
Range on HMM: 1-352/352
Sequence Identity: 20% (73 aa)

YEVLQVLGSGFFGTVYKCQNRIDKNIYAVKVTK-----EQIRGENSQKQILKEAQALASLSACDEVE----------------YIVCYHSAWIEDRQLHL
|......|.| ||.|||||.. .| .|| |  |      |   .|.. .|. |.... ...  . ..                .|| .. .   .  . .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

AMEFC-DSNLANFPLPQPP---------------NYNQFYQMI----KKIFQDVVKGLHYLHQQN-LVHLDLKPENILYNKKQN--KFKIADLGLALIAN
 ||.| . .| ..   ..                .  . .|..    |..|  ...|| |||..|  .| |.||||||......  . ||.|.|..   .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

KDNEKY-------------NQIEE-GDARYL----AKEIL---NYY--EAVDLKKADIFSLGAMMYHLVTQEQLPTNGDE-------------------W
..|...             ..    |  .|.    | |.|   ||.   |   .|.||.|||  .| ..... .| ..                      
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA---YKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWINNAYRKQL

LQIR-QGHLPNLDSLN-----QCPKELKQMIR----QMMNPDPELRLSTQEILDSSYM
.|.  |. . .  . .     . ..| | .|.    .|.. .|. |.. ..||   ..
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 26815.AA CMGC 364-515 18 8.6e-34 107.72 In-house 1-251 (513) Show / Hide 
Range on Protein: 364-515
Range on HMM: 1-251/513
Sequence Identity: 18% (48 aa)

YEVLQVLGSGFFGTVYKCQN--------------RIDKNIYAVKVTKEQIRGENSQK----------QILKEAQALASLS-------------ACDEVEY
||.....|.| .|.||||..              . ...|.|.|  |..   |. .|           .| | . |  |.              ..  ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVCYHSAWIEDR-----------------QLHLAMEFCDSNLANFPLPQPP--------NYNQFY----------QMIKKIF------QDVVKGLH--YL
||. .     .                  .|.| .|..| .|...   ...        . ..            ..||...      . . .||.  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HQQN--LVHLDLKPENILYNKKQNKF-------------------KIADLGLA
|...   .| |||||||| |..   .                   ||.| |||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase 26815.AA CAMK 470-625 20 2.5e-28 87.8 In-house 182-425 (425) Show / Hide 
Range on Protein: 470-625
Range on HMM: 182-425/425
Sequence Identity: 20% (49 aa)

KKIFQDVVKGLHYLHQQNLVHLDLKPENILYNKKQ----------------NKFKIADLGLA--LIANKDNEKYNQIEE--------------------G
...|. .. ..||.|..| ||.||||||||....                 |. ||.| |.|  .. ...| . . ...                    |
RRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG

DARYLA-KEILNYY------------EAVDLKKADIFSLGAMMYHLVTQEQLPTNGD-----------------EWLQIRQGHLP-NLDSLNQ-------
   | |  |.||.             .  . .|.|. |.| ..| ...   .| .||                  . .|..|      . .         
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLC-GYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGP

-------------CPKELKQMIRQMMNPDPELRLSTQEILDSSYM
             . .| |..||.|...||| |.. ...|.   |
EWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 26815.AA STE 364-515 23 3.1e-26 89.72 In-house 1-194 (359) Show / Hide 
Range on Protein: 364-515
Range on HMM: 1-194/359
Sequence Identity: 23% (49 aa)

YEVLQVLGSGFFGTVYKCQNRI---------------DKNIYAVKVTK-----------EQIRGE------NSQKQILKEAQALASLSA-CDEVEYIVCY
.| ....|.| ||||||. |.                 ..|.|.|. .           |  . |      . ..||||| . .  ..  .   ..|| |
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMH---PNIVKY

HSAWIEDR-------QLHLAMEFCD-SNLA-----NFPLPQPPNYNQF------YQMIKKIFQDVVKG-LHYLHQQNLVHLDLKPENILYNKKQNKFKIA
. . . .        .|...||..|   |      ..  ..| | |.        . |..| ....|| |.|||... .| |.|| |||        |..
YGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLC

DLGLA
| |..
DFGVC
Kinase 26815.AA Ciliate-E2a 461-570 37 5.5e-23 64.51 In-house 95-215 (275) Show / Hide 
Range on Protein: 461-570
Range on HMM: 95-215/275
Sequence Identity: 37% (45 aa)

NYNQFYQMIKKIFQDVV-KGLHYLHQQNLVHLDLKPENILYN--KKQN----KFKIADLGLALIANKDNEKYNQIEEGDARYLAKEILNYYEAVDLK---
......| |..| |    .||||.||.| .| ||||||||..  .|..    . ||.| |||  ..|| .||     | . |.| |.||. |    |   
RFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYD

-KADIFSLGAMMYHLVTQEQL
 | |..|.|...| |.. ...
TKCDMWSCGVIFYILLCGKPP
Kinase 26815.AA NEK 364-524 23 2.6e-22 75.67 In-house 1-179 (286) Show / Hide 
Range on Protein: 364-524
Range on HMM: 1-179/286
Sequence Identity: 23% (44 aa)

YEVLQVLGSGFFGTVYKCQNRIDKNI-----YAVKVTKEQIRGENSQKQIL-KEAQALASLSACDEVEYIVCYHSAWIEDR--QLHLAMEFCDS--NLAN
||.....|.| ||.|||.. ..|...     |. |  . .   |  ... . .|.. |..|      ..|| |. ..||.   .|.  ||.|.   .|..
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKH----PNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQ

F------------PLPQPPNYNQFYQMIKKIFQDVVKGLHYLHQQ-----NLVHLDLKPENILYNKKQN---KFKIADLGLALIANKDNEK
.            ...          .| ..|.  ...|.|.|..     . .| |.|| ||  .|. |     || |.|.. . |.....
KIKSIKKQKQKGKYFEEE--------QIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDM
Kinase 26815.AA PEK 469-625 20 2.2e-17 56.45 In-house 429-655 (655) Show / Hide 
Range on Protein: 469-625
Range on HMM: 429-655/655
Sequence Identity: 20% (48 aa)

IKKIFQDVVKGLHYLHQQNLVHLDLKPENILYNKKQN----KFKIADLGLAL-----------------------IANKDNEKYNQIEE-----------
...||.....|| |.|.| ..| |||| ||.   ...    . ||.| |||                        .... ... ..              
CWRIFRQILEGLNYIHSQGMIHRDLKPSNIFLDCDGQHHQMQVKIGDFGLATNHEMLSQSQKNYNQQDQSYWKYVANDNCQWWNTNQQNSPTGQDTHMWS

----------------------GDARYLAKEIL---NYYEAVDLKKADIFSLGA----MMYH-LVTQ-EQLPTNGDEWLQIRQ------GHLPNLDSLNQ
                      | ..| . | |   .|  .   .|.|..|||     |.|.   |. |   |  |    .|.      | .|. ... .
NNYHIQPTSMFYCEHCHHTGGVGTCLYMSPEQLSGQHYQKSHYNHKVDMYSLGIIFFEMWYPFFTTMMERVKTLTD----LRDESIQFPGDFPP-KWFDN

CPKELKQMIRQMMNPDPELRLSTQEILDSSYM
  ......|..|...||. | |.|.||..  .
KYPKQADFIQWMLSHDPQQRPSAQQILQHEFF
Kinase 26815.AA PEK 364-438 34 1.6e-14 46.27 In-house 137-223 (655) Show / Hide 
Range on Protein: 364-438
Range on HMM: 137-223/655
Sequence Identity: 34% (31 aa)

YEVLQVLGSGFF-GTVYKCQNRIDKNIYAVKVTKEQIRG------------ENSQKQI---LKEAQALASLSACDEVEYIVCYHSAWIEDR
.|..|.||.| | | |||.||..|.. ||.|  | ....            ....|..   |.|...||.|.     ..|| ||.||||..
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARLNH----PNIVRYHNAWIEKP
Kinase 26815.AA TyrKc 364-625 21 1.8e-13 -4.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 364-625
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

YEVLQVLGSGFFGTVYKCQNRIDKNIYAVKVTKEQIRGENSQKQILKEAQALASL--SACDEVEYIVCYHSAWIED-------RQLHLAMEFCDS-NLAN
 . ...||.|.||.|||.. .      |||. ||       .. ...||. . .|  .     . ||. . . ...        .| . ||...  .| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHH----PNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

FPLPQPPNYNQFYQMIKKIFQDVVKGLHYLHQQNLVHLDLKPENILYNKKQNKFKIADLGLALIANKD-----NEKYNQIEE---GD----ARYLAKEIL
.     |.     .   ..  .. .|  |||..|..| ||   |.|.....   ||.| ||.     |     ...|    |   |.     | .| | .
YLRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

NYYEAVDL---KKADIFSLGAMMYHLVTQEQLPTNG-----DEWLQIRQGHLPN--LDSLNQ--------CPKELKQMIRQMMNPDPELRLSTQEILDSS
      .     | |..| | .|. . |  | |  |      .. ....       ..            ||.|. |...|  . ||| | . .||   .
-----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HE

YM
..
CF
Kinase 26815.AA Ciliate-E2a 590-625 27 2.4e-10 26.66 In-house 240-275 (275) Show / Hide 
Range on Protein: 590-625
Range on HMM: 240-275/275
Sequence Identity: 27% (10 aa)

SLNQCPKELKQMIRQMMNPDPELRLSTQEILDSSYM
....|.|| |.....| ..||. |.. |..|.. ..
CWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 26815.AA NEK 578-625 30 7.8e-10 31.21 In-house 238-286 (286) Show / Hide 
Range on Protein: 578-625
Range on HMM: 238-286/286
Sequence Identity: 30% (15 aa)

LQIRQG-HLPNLDSLNQCPKELKQMIRQMMNPDPELRLSTQEILDSSYM
..|..| . | . | ..  ..|...|.|| ..|||.| |...||  ...
MKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 26815.AA CAMK 369-448 12 1.1e-09 26.7 In-house 1-143 (425) Show / Hide 
Range on Protein: 369-448
Range on HMM: 1-143/425
Sequence Identity: 12% (18 aa)

VLGSGFFGTVYKCQNRIDK------------NIYAVKV-TKEQIRG-------------------------ENSQKQILKEAQALASLSACDE---VEYI
.||.| ||.|..|... ..              .|.|.  |.....                         ....|....| . . .|.. ..    . |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VCYHSAWIE-------------------DRQLHLAM---EFCD
.  . ..                     |..... |   |.|.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCS
Kinase 26815.AA Ciliate-E2a 364-396 30 4.8e-09 22.78 In-house 1-33 (275) Show / Hide 
Range on Protein: 364-396
Range on HMM: 1-33/275
Sequence Identity: 30% (10 aa)

YEVLQVLGSGFFGTVYKCQNRIDKNIYAVKVTK
|... ..|.|.|| ||. | ....  .|.|. .
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFI
Kinase 26815.AA STE 551-625 15 1e-06 19.84 In-house 248-359 (359) Show / Hide 
Range on Protein: 551-625
Range on HMM: 248-359/359
Sequence Identity: 15% (17 aa)

KADIFSLGAMMYHLVTQEQL----PTNGDEWLQIRQ--------------GHLPNLDS-----------------LNQCPKELKQMIRQMMNPDPELRLS
|.|| ||| .. ...| .      .     .. ..               |. | | .                   .. .|.|. |..  . ||. | .
KCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT

TQEILD--SSYM
... |    .  
ASQLLKSEHPFI
Kinase 26815.AA CMGC 592-625 20 0.001151 6.89 In-house 480-513 (513) Show / Hide 
Range on Protein: 592-625
Range on HMM: 480-513/513
Sequence Identity: 20% (7 aa)

NQCPKELKQMIRQMMNPDPELRLSTQEILDSSYM
..|....   . .|.  ||. |.. ...|.  | 
KCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 26815.AA Pkinase_Tyr 364-419 29 0.001325 12.83 Pfam 1-62 (270) Show / Hide 
Range on Protein: 364-419
Range on HMM: 1-62/270
Sequence Identity: 29% (18 aa)

YEVLQVLGSGFFGTVYKCQNR----IDKNIYAVKVTKEQIRGEN-SQKQILKEAQALASL-S
 . ...||.| ||.|||.  .     .|   |||. ||.   |.  ..  ..||. . .| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGH
Kinase 26815.AA Pkinase_Tyr 478-515 44 1.140805 2.89 Pfam 122-158 (270) Show / Hide 
Range on Protein: 478-515
Range on HMM: 122-158/270
Sequence Identity: 44% (17 aa)

KGLHYLHQQNLVHLDLKPENILYNKKQNKFKIADLGLA
||. ||...|..| ||   |.| .. .|. ||.| |||
KGMEYLESKNCIHRDLAARNCLVTE-NNVVKICDFGLA