26581

Species: Tetrahymena
Alias: 3702.m00003, 26581, PreTt26581, 11.m00278, TTHERM_00140760, 500
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: TKL
Family: TKL-ciliate2

Sequence

Name Sequence Type Origin Length Description Download
26581.AA Protein None 1011 None Fasta, JSON
26581.kin_dom Protein Kinase Domain None 217 None Fasta, JSON
26581.NA RNA None 3036 None Fasta, JSON

Protein domain

Protein domains of 26581.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RCC1 26581.AA RCC1 189-210 23 0.011379 11.55 Pfam 28-52 (52) Show / Hide
Range on Protein: 189-210
Range on HMM: 28-52/52
Sequence Identity: 23% (6 aa)

SQ-IQISLS---IVQISAGDNHVIIL
.| ...  .   .||...|..|...|
QQIVEFL-GNVRVVQVACGWQHTMAL

RCC1 26581.AA RCC1 215-262 36 4.8e-08 28.99 Pfam 3-52 (52) Show / Hide
Range on Protein: 215-262
Range on HMM: 3-52/52
Sequence Identity: 36% (19 aa)

RVFSQGSNNYGQLG-IVGQSFLEKF-SC-VEVLLN-HQIQQISCGSDFSFAL
||.. |.|.||||| | | .  .   .. || | .   ..|..||.....||
RVYTWGCNDYGQLGRIHGDT-NCHVPQQIVEFL-GNVRVVQVACGWQHTMAL

RCC1 26581.AA RCC1 282-317 37 1.2e-11 40.66 Pfam 1-38 (52) Show / Hide
Range on Protein: 282-317
Range on HMM: 1-38/52
Sequence Identity: 37% (15 aa)

KGEVFSWGQNCKGQLG--LGMNQNVQIPTL-VESLVN-KE
.|.|..||.|  ||||  .| . |. .|.. ||.| . ..
DGRVYTWGCNDYGQLGRIHGDT-NCHVPQQIVEFL-GNVR

RCC1 26581.AA RCC1 384-397 50 0.032512 10.07 Pfam 39-52 (52) Show / Hide
Range on Protein: 384-397
Range on HMM: 39-52/52
Sequence Identity: 50% (7 aa)

VSKISCGSLHTLAL
|....||. ||.||
VVQVACGWQHTMAL

RCC1 26581.AA RCC1 400-423 30 0.528139 6.14 Pfam 1-25 (52) Show / Hide
Range on Protein: 400-423
Range on HMM: 1-25/52
Sequence Identity: 30% (8 aa)

HGKIYSSGYGESFALG--HGDEQSTN
 |..|. |...   ||  |||. . .
DGRVYTWGCNDYGQLGRIHGDT-NCH

RCC1 26581.AA RCC1 508-523 31 32.976181 0.31 Pfam 37-52 (52) Show / Hide
Range on Protein: 508-523
Range on HMM: 37-52/52
Sequence Identity: 31% (5 aa)

QKVIEIQCGQAITLLL
..|. . ||   |..|
VRVVQVACGWQHTMAL

RCC1 26581.AA RCC1 578-627 28 8.1e-07 25.01 Pfam 3-52 (52) Show / Hide
Range on Protein: 578-627
Range on HMM: 3-52/52
Sequence Identity: 28% (15 aa)

KVYGWGSNQYGQLD-QGSSLQMVVTPIE-VANLNAENQTVLLSCGGNVSYVV
.||.||.|.||||  .. .   . .|   |  |  ..  |  .||.. . ..
RVYTWGCNDYGQLGRIHGDT-NCHVPQQIVEFL-GNVRVVQVACGWQHTMAL

Kinase 26581.AA TKL-ciliate2 765-984 82 8.60000000001e-183 613.56 In-house 1-240 (273) Show / Hide
Range on Protein: 765-984
Range on HMM: 1-240/273
Sequence Identity: 82% (199 aa)

LEIQNKITEGGYGIIYKAKWREIVVAVKKFKIDYNNQQQIVEFVNECNAMEALRHPNIVLFLGACTEIPNFSIVMEYCQRGSLWSLLQNQSVPLTWEDRR
|||||||||||||||||||||||||||||||.|..|||||..|||||.|||||||||||.||||||.||||.|.||||||||||||||||.|.|||||||
LEIQNKITEGGYGIIYKAKWREIVVAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTWEDRR

KIALDIAKGVFFLHSSKPPIIHRDLK--------------------SLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEVIKAFYYTEKAD
.||||||.||..||||.|||||||||                    ||||||||||||||||||||||||||||||||||||||||||||||||||||||
RIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEVIKAFYYTEKAD

VFSYSIILWEIASREPPYRGIKGDVVAEKVMCENLRPIIP
|||||||||||||||||||..|||||||||||.|||| ||
VFSYSIILWEIASREPPYRNKKGDVVAEKVMCNNLRPTIP

Kinase 26581.AA TKL 771-986 31 1.7e-88 300.3 In-house 1-322 (364) Show / Hide
Range on Protein: 771-986
Range on HMM: 1-322/364
Sequence Identity: 31% (104 aa)

ITEGGYGIIYKAKWRE----------IVVAVKKFKIDYNN------------------------QQQIVEFVNECN-AMEALRHPNIVLFLGACTEIPN-
| .||.|..||.|||            .|||||||.....                        .... .| .|    |  |||||||.|.|.|...|. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FSIVMEYCQRGSLWSLLQNQSVPLTWEDRRKIALDIAKGVFFLHSSK------PPIIHRDLKSLNVLVDDNFR--------------C
            . ||||||..|||...|.       |. | ..|||||.|. .|||..      |||||||||| |.|||.|..              |
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLTDFGWTRVKPQDNYMTN--------------------KIGTYQWMAPEVIK----------------AFYYTEKADVFSYSIILWEIASREPPYRGIK
|..|||  |.. |.. |.                     ..||..||||||..                 | |.||.||.|. |.||||..|..||....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

-GDVVAE-------KVMC-ENLRPIIPPR
  ....        .. | ..||| |||.
YMPMIFQDPFEEMFMMVCDKGLRPPIPPI

Kinase 26581.AA TKL-Unique 767-986 40 2.8e-86 292.92 In-house 1-260 (290) Show / Hide
Range on Protein: 767-986
Range on HMM: 1-260/290
Sequence Identity: 40% (107 aa)

IQNKITEGGYGIIYKAKWREIVVAVKKFKIDYNNQQ-QIVE-FVNECNAMEALR-HPNIVLFLGACT----EIPNFSIVMEYCQRGSLWSLLQ-------
. ||| ||||| .||.||| . ||.|.|..  . .  .... | || | |. |. |||||.. |.|.     .||..||||||..||| ..|.       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--NQSVPLTWEDRRKIALDIAKGVFFLHSSKPPIIHRDLKSLNVLVDDN-----FRCKLTDFGWTRVKPQDNYMTNK----------IGTYQWMAPEVIK
  |.. .|... | |.|.|||.|  .||...||||||||||.|.||| |     .. |. |||  ... ..| |||.          .|...||||||..
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

A--FYYTEKADVFSYSIILWEIASREP------PYRGIKGDVVAEKVMC--ENLRPIIPPR
   . |.||.||.|..|.|||||.|.       ||.|.  . ..|.|    ||.|| ||..
MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNH

Kinase 26581.AA Dicty4 765-985 39 1.9e-84 281.54 In-house 1-242 (277) Show / Hide
Range on Protein: 765-985
Range on HMM: 1-242/277
Sequence Identity: 39% (96 aa)

LEIQNKITEGGYGIIYKAKWREIVVAVKKFKIDYNN--QQQIVEFVNECNAMEALRHPNIVLFLGACT----EIPNFSIVMEYCQRGSLWSLLQN-----
. |...| .|..|  ||..|| . |||||.. .  |  .  . || .| . |  .|||||.||.||||    . . ..||.||. .|.| ||| .     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-QSVPLTWEDRRK---IALDIAKGVFFLHSSKPPIIHRDLKSLNVLVDDNFRCKLTDFGWTR----VKPQDNYMTNKIGTYQWMAPEVIKAFYYTEKADV
 ||..| |.....   .|.|.|.|.  ||.. | |||||||| | |||.|.| | .|||  .    .. .   ..  .||  ||||||     |.|||||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

FSYSIILWEIASREPPYR--GIKGDVVAEKVMCENLRPIIPP
.|..|.||||. |. ||   ..  . ... |  . |||.||.
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPD

Kinase 26581.AA DRK 765-985 41 7.6e-82 276.96 In-house 1-225 (258) Show / Hide
Range on Protein: 765-985
Range on HMM: 1-225/258
Sequence Identity: 41% (93 aa)

LEIQNKITEGGYGIIYKAKWREIVVAVKKFKIDYNN-QQQIVEFVNECNAMEALRHPNIVLFLGACTEIPNFSIVMEYCQRGSLWSLLQNQSVPLTWEDR
  |.| |  |.|| ..   || . ||||. . .  |    . ||  | | |  ||||||..|.|.|.. |   |.|||  |||| . | ..|. . |  .
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

RKIALDIAKGVFFLHSSKPPIIHRDLKSLNVLVDDNFRCKLTDFGWTR----VKPQDNYMTNKIGTYQWMAPEVIKAFYYTEKADVFSYSIILWEIASRE
 ....|.|||. .||.. | |||||||| | |||.... |  |||       .| .   ||  .||  | ||||     |||||||.|. |.|||.. |.
KQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMT-MCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQ

PPYRGIKGDVVAEKVMCENLRPIIPP
 || |.    |   |  . .||..|.
DPYFGMPTFQVVFSVGRHGMRPPMPQ

Kinase 26581.AA MLK 765-985 34 2.3e-71 243.4 In-house 1-260 (291) Show / Hide
Range on Protein: 765-985
Range on HMM: 1-260/291
Sequence Identity: 34% (90 aa)

LEIQNKITEGGYGIIYKAKWREIV-----VAVKKFKIDYNNQQQI-----VEFVNECNAMEALRHPN----IVLFLGACTEIPN-FSIVMEYCQRGSLWS
.... .| .|..|  .|..||        ||||.....     ..      .|  ||.    |.|||    |. |.|.|.. |. | ||||||. ||| .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

LLQNQS-------------VPLTWEDRRKIALDIAKGVFFLHSSKP-PIIHRDLKSLNVLVDD------NFRCKLTDFGWTRVKPQD-NYMTNKIGTYQW
.| ...             .  . .   ..||..|.|. .||| .| ||||||||| |.|.|.      .  .| .|||  | . |    |....||| |
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MAPEVI---KAFYYTEKADVFSYSIILWEIASREPPYR-GIKGDVVAEKVMCENLRPIIPP
||||||   ..  |.||.||.|. ..|||. .|| ||. ....  .| .|  ..||| ||.
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPS

Kinase 26581.AA LRRK 765-985 29 2.8e-62 213.24 In-house 1-312 (351) Show / Hide
Range on Protein: 765-985
Range on HMM: 1-312/351
Sequence Identity: 29% (94 aa)

LEIQNKITEGGYG-IIYKAKWRE----------------------------IVVAVKKFKID---------YNNQ-----------------------QQ
|.|...| .||.| ..|.||||                               ||.||...|          .|                          
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

IVEFVNECNAMEALRHPNIVLFLGACTEIPNFSIVMEYCQRGSLWSLLQNQS-VP-------LTWEDRRKIALDIAKGVFFLHSSKPPIIHRDLKSLNVL
  || .|.  |  |.|||||  .| | . | . .|||| . |.| ..|.| .  .       ..|  . ||||.||||. .|||..|||||||||| |.|
FREFRHEVWIMSHLNHPNIVSLKGFCIH-P-LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

V---D---------DNFRCKLTDFGWTRVKPQDNYMT---NKIGTYQWMAPEVIKAF---YYTEKADVFSYSIILWEIASRE-PPYRGIK----G--DVV
.   .         ..  .|. ||| .|.  |  .|.    . |. .|||||....     ||||.|..|. .||||. .|. .|.....    .     
LWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQ

AEKVMCENLRPIIPP
 |. . | ||| ||.
IEDKIIEGLRPTIPQ

Kinase 26581.AA Pkinase 765-984 28 1.9e-57 201.96 Pfam 1-236 (293) Show / Hide
Range on Protein: 765-984
Range on HMM: 1-236/293
Sequence Identity: 28% (69 aa)

LEIQNKITEGGYGIIYKAKWREIV--VAVKKFKIDYNNQQQIVEFVN--ECNAMEALRHPNIVLFLGACTEIPNFSIVMEYCQRG----SLWSLLQ-NQS
..|  || .|..|  ||....     ||||..| . .. .. .. ..  |.  |  |.||||| ....... ..  .|||||. |    .|.....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VPL--TWEDRRKIALDIAKGVFFLHSSKPPIIHRDLKSLNVLVDDNFRC----KLTDFGWTRV--KPQDNYMTNKIGTYQWMAPEVIK-AFYYTEKADVF
 ..  .... ..... |..|. ..||    |||||||. |.|.|.|  .    |..|||  ..     .  ||   ||. .||||||. . ||. |.|..
GCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SYSIILWEIASREPPYRGI---KGDVVAEKVMCENLRPIIP
|. .||.| ....||..|    .. .   ...|....|...
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLH

Kinase 26581.AA CZAK 765-966 36 4.2e-57 196.01 In-house 1-226 (279) Show / Hide
Range on Protein: 765-966
Range on HMM: 1-226/279
Sequence Identity: 36% (83 aa)

LEIQNKITEGGYGIIYKAKWREIVVAVKK-FKIDYNNQQQ---IVEFVNECNAMEALRHPNIVLFLGACTEIP--NFSIVMEYCQRGSLWSLLQNQSVPL
|..   | .| .| .||| ||. .||.|. ... . |       . | .|   |  |.|||.| |||||.|      .||||.   |||  ||   .  .
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

TW--EDRRKIALDIAKGVFFLHS-SKP-PIIHRDLKSLNVLVDDNFR-------------CKLTDFGWT-RVKPQDNYMTNKIGTYQWMAPEVIKAFYYT
      . ..|.|||.| ..||   || ||.|||| | |.| |..               ||  |||     ..|   ||  .|   |||||. |.  ||
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYT

EKADVFSYSIILWEIASREPPYRGIK
||.||.|. .|||.|   . || ...
EKVDVYSFGMILWCIITCDQPYQNMQ

Kinase 26581.AA HH498 765-962 34 3.2e-54 170.09 In-house 1-226 (284) Show / Hide
Range on Protein: 765-962
Range on HMM: 1-226/284
Sequence Identity: 34% (79 aa)

LEIQNKITEGGYGIIYKAKWREIVVAVKKFKID-YNNQQQ-----IVEFVNECNAMEALRHPNIVLFLGACTEIP-NFSIVMEYCQRGSLWSLL------
.| . ||  | .| .|| .||  .|||| ...  .             |. |   |  | ||. | |..|| . |  | || .||. |||.|.|      
IEFHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIPIG

--------QNQS---VPLTWEDRRKIALDIAKGVFFLHS-SKPPIIHRDLKSLNVLVDDNFRCKLTDFGWTRVKPQ--DNYMTNKIGTYQWMAPEVIK-A
         ||      .    .  |..|.|.|  .||.  |.||||||| | |.|.. . . .  |||  | . .  |  ||  .|   |||||| .  
GAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQC

FYYTEKADVFSYSIILWEIASREPPY
  |..|.||||| ...||. .|| |.
QKYSIKVDVFSYAMCIWEMHTREVPF

Kinase 26581.AA Pkinase_Tyr 765-974 34 1.7e-53 181.8 Pfam 1-228 (270) Show / Hide
Range on Protein: 765-974
Range on HMM: 1-228/270
Sequence Identity: 34% (80 aa)

LEIQNKITEGGYGIIYKAKWR------EIVVAVKKFKIDYNNQQ-QIVEFVNECNAMEAL-RHPNIVLFLGACT--EIP-NFSIVMEYCQRGSLWSLLQN
...  |. || .| .||..|.      .| ||||. | ..  .|  . .| .| . |  | .||||| ..|.||  . | .  |||||.. |.| . |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

Q---SVPLTWEDRRKIALDIAKGVFFLHSSKPPIIHRDLKSLNVLVDDNFRCKLTDFGWTRVK-PQDNY---MTNKIGTYQWMAPEVIKAFYYTEKADVF
.     ||| .|  .....||||  .|.| .  .|||||   |.||..|. .| .||| .|   . |.|    ..      |||||.|.   .|.| || 
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SYSIILWEIASRE-PP-YRGIKGDVVAEKV
|. . .||| ..   | | |..   | |..
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYI

Kinase 26581.AA ARK 765-958 38 2.6e-52 180.09 In-house 1-211 (280) Show / Hide
Range on Protein: 765-958
Range on HMM: 1-211/280
Sequence Identity: 38% (81 aa)

LEIQNKITEGGYGIIYKAKWREIVVAVKKFKIDYNNQQQIVEFVNECNAMEALRHPNIVLFLGACTEIP----NFSIVMEYCQRGSLWSLLQNQSVPLTW
||  .|| .| ..  ||.|.|  .||.| .|      .|| ||  |.  | ..| |..| | ||| |        ..|||||.||||  .. | .   .|
LEYTCKIGSGSSCKVYKGKYRGKEVAIKVLKSIMTDSMQIEEFKKEFQIMSSIRSPHVVYFYGACIEPEPQKQKLCMVMEYCSRGSLYHIMNNNKMDFGW

EDRRKIALDIAKGVFFLHSSKPPIIHRDLKSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTN-KI-GTYQWMAPEVIK-----------AFYYTEKADVFS
.   | .  .  |.  ||...|.|.|||||||| || .|. ||. ||| .|    .|  |. |. ||.   ||||                ||.|.||.|
DRFFKWMMQMVRGINCLHNWTPQIVHRDLKSLNLLVNENWTCKVCDFGLSRFNTMSNQETLGKMRGTFAYCAPEVYYFQDIDDDYVSNGKHYTTKSDVYS

YSIILWEIASR
  ||.||...|
MGIIMWEMVYR

Kinase 26581.AA TyrKc 765-1002 28 6.8e-45 156.39 SMART 1-280 (280) Show / Hide
Range on Protein: 765-1002
Range on HMM: 1-280/280
Sequence Identity: 28% (83 aa)

LEIQNKITEGGYGIIYKAKWREIVVAVKKFKIDYNNQQQIVEFVNECNAMEAL--RHPNIVLFLGACTEI-------PNFSIVMEYCQRGSLWSLLQNQS
..   |. || .|..||..|. | ||||. | |      . .| .| . |  |  .||||| ..|.||.        .   |||||.  |.| . |..  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

VPLTWEDRRKIALDIAKGVFFLHSSKPPIIHRDLKSLNVLVDDNFRCKLTDFGWTRVKPQD-------NYMT-----NKI--GTYQWMAPEVIKAFYYTE
  |...|  .....||.|  .|||   ..|||||   |.||..|...| .||| .|    |        | .     ..     . |||||.|.   .|.
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KADVFSYSIILWEIASR-EPPYRG-----IKGDVVAEKVMCENLRPIIPP---------------------RRKSRQ-QTYVQINSQRF
| ||.|. . .||| .. ..|| |     .. . | |.|.  . .|. |                      ...  .  |  .|  ..|
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF

Kinase 26581.AA S_TKc 765-1010 23 5.6e-38 133.41 SMART 1-231 (231) Show / Hide
Range on Protein: 765-1010
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

LEIQNKITEGGYGIIYKAKWRE--IVVAVKKFKIDYNNQQQIVEFVNECNAMEALRHPNIVLFLGACTEIPNFSIVMEYCQR--GSLWSLLQNQSVP---
 || .|| .|..|  ||.....   .||.|. |           . .| . ..  .||||| ..... .  .. .|||||    |.| ......  .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LTWEDRRKIALDIAKGVFFLHSSKPPIIHRDLKSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEVIKAFYYTE-KADVFSYSIILWE
  ..  . |...  |.... ..||    |||||||  |.|.|.  . |..|||  |.       |  .||  .|||||.    |.  |.|. |  .||.|
FPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

IASREPPYRGIKGDVVAEKVMCENLRPIIPPRRKSRQQTYV-------QIN-SQRFRSDDYGM----------I
 ....||..        ...| ....           .          | . ..|    .             .
MLCGYPPFP-------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF