Gene RSKL (Sea Urchin)

RSKL

Species: Sea Urchin
Alias: Spk029, SPU_010957, RSKL
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: AGC
Family: RSKL

Sequence

Name Sequence Type Origin Length Description Download
RSKL.AA Protein None 1489 None Fasta, JSON
RSKL.kin_dom Protein Kinase Domain None 157 None Fasta, JSON

Protein domain

Protein domains of RSKL.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PX RSKL.AA PX 3-114 22 5.8e-11 40.11 Pfam 1-120 (120) Show / Hide 
Range on Protein: 3-114
Range on HMM: 1-120/120
Sequence Identity: 22% (28 aa)

TSTKKETWIRSFNVTEPTKHEKGFTVYKVTYRV--------AVWKRYNDFKKLHQALSLLHYHLRRPEKFPDFAKARFFGR---FDEKTIEERRQSALRL
....  . .... .... .... ..||.....          ||.||.|| .||. |   .       ..| .   . |||   |||. ||.|||   . 
DHFLQVHVVDPETHKHYGDKMHYYYVYEIHMNTNPFQKKEWHVWRRYSDFHWLHKQLKRHFP----MCIIPPLPPKHWFGRYNNFDEEFIEKRRQMLEQY

LEFTVKVPPLAK-STHFVEFFKGG
|.  .. |.|.. . .| .|.   
LQRVCQHPELCNHCEVFHDFLHPD
PX RSKL.AA PX 8-114 20 7.5e-11 43.3 SMART 1-142 (142) Show / Hide 
Range on Protein: 8-114
Range on HMM: 1-142/142
Sequence Identity: 20% (29 aa)

ETWIRSFNVTEPTK------HEKGFTVYKVTYRVA-------VWKRYNDFKKLHQALSLLHYHLRRPEKFPDFAKARFFGR------------------F
. . .   |...|.      ..  ..||..... .       |..||.|| .||. |.  .....|  ..| .     |.|                  |
DHIFIITVVEFFTHGKHYHDGKHYYYVYEIHTKTNNHVKMWTVYRRYSDFHWLHHQLKRHFPQEKRMCIIPPLPPKHWFVRYRYWMEHMSMMWWYSFNNF

DEKTIEERRQSALRLLEFTVKVPPLAK----STHFVEFFKGG
||. ||.||..  | |.  .. |....    . .. |||   
DEDFIEKRRRGLERYLQRLCHHPEWINHYMVCEVVYEFFESS
MIT RSKL.AA MIT 397-465 23 6.3e-18 65.35 Pfam 1-71 (71) Show / Hide 
Range on Protein: 397-465
Range on HMM: 1-71/71
Sequence Identity: 23% (17 aa)

YLYQAAGKISMALDNES-VGNYQASFDAYKAGVAILLKGVVADKSKTRREA-VRRKTAQYLMKAEDIYNKY
|| .|   ...|.. .   |||.. ...|. .. ...... .... ..||| .|.|...|. .||.| .  
YLQKAIELVKKAVEADEDAGNYEEAIQCYQEAIEYFMQAIKYEPNPKWREARLRQKMQEYMDRAEQIKEHL
MIT RSKL.AA MIT 394-471 24 5.8e-15 56.96 SMART 1-81 (81) Show / Hide 
Range on Protein: 394-471
Range on HMM: 1-81/81
Sequence Identity: 24% (20 aa)

EDDYLYQAAGKISMALDNES--VGNYQASFDAYKAGVAILLKGVVAD-KSKTRREAVRRKTAQYLMKAEDIYNKYLSVEAS
 .||...|.  |. |.. .    |.|.. ...|. |. .|..|.  . ....||.|...| ..||...|.| | ... .. 
QRDYYQKAIEYITQAVKADEDEWGDYEQAIEHYQKGIDYLMQGIKYEKPDEKRRHAIWAKCREYLDRMEEIKNCHDWRLCP
Kinase RSKL.AA RSKL 1323-1479 60 1.1e-163 404.25 In-house 269-436 (436) Show / Hide 
Range on Protein: 1323-1479
Range on HMM: 269-436/436
Sequence Identity: 60% (102 aa)

TLPESCVRIWASEILFALATLHAAG-IICRDLNPDNILLAEGGHIRLTYFSQWK-------WVCQEMNLKALTNMYTAPEAGSIFGVGPACDWWSYGTIL
..||.|.|.||.|...||..|||.| .||||||||||||...|||.||||.||.       ||||..|..|.||||.|||.|.|.....||||||||..|
DIPEQCIRQWACEMVVALHALHAEGHVICRDLNPDNILLDQKGHIQLTYFGQWSGLTSDDNWVCQQCNREAVTNMYCAPEVGQIWELTEACDWWSYGAVL

FELLTGQSLYSCHPSGISSHTQLFIP---DHISPEAKNLLTQLLQVNPLERLGGGQSGADEVKAHPFF
.|||.|.|||.|||.||..||||..|   ...|..||.|||||||.||.||||.||.|.||.||||||
YELLCGMSLYQCHPHGIQRHTQLQMPSEKEWVSHHAKDLLTQLLQFNPMERLGMGQGGVDEIKAHPFF
Kinase RSKL.AA AGC 1323-1479 25 3.3e-74 190.4 In-house 142-395 (395) Show / Hide 
Range on Protein: 1323-1479
Range on HMM: 142-395/395
Sequence Identity: 25% (67 aa)

TLPESCVRIWASE-------ILFALATLHA-AGIICRD-LNPDNILLAEGGHIRLTYFSQWKWVCQEM--------------------------------
...|...|..|.|       |. ||  ||   |||.|| | |.|||| | |||.|| |  .|.. ...                                
RFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPN

--------------------NLKAL---TNMYTAPEAGSIFGVGPACDWWS--YGTILFELLTGQSLYSCH-----------PSGISSHTQ---------
                    .       |  | |||       |.||||||  .| ...|.|||.. .. .           |  .    .         
NWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWK

LFIP----------DHISPEAKNLLTQLLQVNPLERLGGGQS-----GADEVKAHPFF
. .|          ...|||||.|...||...| .||| |..     ||.|.|.||.|
VKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase RSKL.AA RSKL 503-575 39 2.8e-34 79.68 In-house 2-74 (436) Show / Hide 
Range on Protein: 503-575
Range on HMM: 2-74/436
Sequence Identity: 39% (29 aa)

KVLGCINSVLLVLDMSTYQTFIIKSLSKCCVPNTKMITRVPAYCPYMVRLYRYFETESSIFLLLEHATGGKLW
.| | |. |..| |  |  ||....| .| ..     . .|   |||..| |||..| .|||.|||  .| ||
RVVGIIKKVQVVQDPATGNTFYVMKLPRCHMVSRDCSIFIPHNVPYMTQLVRYFVSEDHIFLHLEHVQPGQLW
Kinase RSKL.AA Ciliate-E2 546-1479 5 1.7e-29 98.4 In-house 91-365 (365) Show / Hide 
Range on Protein: 546-1479
Range on HMM: 91-365/365
Sequence Identity: 5% (58 aa)

CPYMVRLYRYFE--TESSIFLLLEHATGGKLWNYAS----PYLQQQREATGKHELANSLKSSTVSRQSQRSRSGSTRSGRGLKDDVFIVAEAFTEDVSQL
.|. ...| .|.  ....|.| .| . || |. |        ....                                                      
HPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE-----------------------------------------------------

EDMPKDAIPGDPDAASVSSMEGKLVTLPEISSSYVNLLDACGEYVTGGGPLGDGETIPQRLSDSNLNDLVTQSSNYDECGDNVRTDQDDSLFLSDTNEET
                                                                                                    
----------------------------------------------------------------------------------------------------

EMFNQGDVFGSTPCKVDIPDQRETVSNAPPASMALFSIDSIDSPNEYSIGEMGDSSAFGFDSSSTIGHLVEDAVLDETGSVDLRVKPETQKQDLDPARVI
                                                                                                    
----------------------------------------------------------------------------------------------------

AEALAVVQEVEQMRKEEAEFILDNSLSHEVPRQENMPTFSDKSNIMEEIVTNTKSTSHTSYDSTVESSQAFLDTRAFGVFNEKEMVPGVDLADFFDSGSQ
                                                                                                    
----------------------------------------------------------------------------------------------------

SPKKRSQSLSEKASRHDPKDTFSGEPRPHPPFMHSASMFNTLVNEPLGKNFLSRDTKRTVSMGGESQSREGNDWNSFFDGDVTDTKGFGFDTSTESKETE
                                                                                                    
----------------------------------------------------------------------------------------------------

IKSLDFDGKETAEHDAPGVFTLPDVPKDIPRDDDDDRIGDVFDVKEDPNMADIYIQGDNRLDMSSGDQNEVDTLGQPRQNPDGATSEEIEKEMQNTDSKR
                                                                                                    
----------------------------------------------------------------------------------------------------

GGNLSHANQKDMNLHINPFDNDNQLVITNRTDSNSSMTYVSVNPSDAKLPCTGVMKDFPSSSTISAQSTPQHTFKPINSNPEIASQCCNIVTAPDVKAVL
                                                                                                    
----------------------------------------------------------------------------------------------------

SSTSAVSTDSAYALCQSGEAMEDNIYGGEDGSVGEANTTPTNSRTSTLKGEHLGMQDTSLPSLSRLFSHLDDVRRSRAESSAATLPESCVRIWASEILF-
                                                                              .     . |  ..    .||  
------------------------------------------------------------------------------K-D-KYFTEKEIKYIMKQILQG

--------------ALATLHAAG-IICRDLNPDNILLAEGGHIRLTYFS-------------QWKWVCQEMNLKA-----------------------LT
              ||  ||  . || ||. |.|||.     | .. |              . |  |...                            |
FKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGT

NMYTAPEAGSIFGVG-----------PACDWWSYGTILFELLTGQSLYSCHPSGISSHTQ----LF----------------IPDHISPEAKNLLTQ---
 .| |||   . | .            .||.|| | ||.|.|.|.  .      .  . |    ..                .....|.|.|.|. .   
PGYMAPEI--LNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGK

-LLQVNPLERLGGGQSGADEVKAHPFF
 .||..| .|..    |..... ||.|
RMLQKDPEKRIT----GWEQILNHPWF
Kinase RSKL.AA p70 1323-1479 31 1.2e-25 89.83 In-house 124-299 (299) Show / Hide 
Range on Protein: 1323-1479
Range on HMM: 124-299/299
Sequence Identity: 31% (55 aa)

TLPESCVRIWASEILFALATLHAAGIICRDLNPDNILLAEGGHIRLTYFSQWKWVCQEMNL--------KAL-----TNMYTAPEAGSIFGVGPACDWWS
...|  ..  .|||  ||  ||  ||| ||| |.|..| . ||. || |   |   ..            |.     |  | |||  .  | . |.||||
IWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCGTIEYMAPEILMRCGHNHAVDWWS

YGTILFELLTGQSLY--SCHPSGISS--HTQ--LFIPDHISPEAKNLLTQLLQVNPLERLGGGQSGADEVKAHPFF
 |  ..  |||.  .  . .   | .       | .|   ..|.. |. .||  .| .|.|.| . | ....||||
LGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase RSKL.AA Akt 1439-1479 51 8.7e-20 59.85 In-house 222-264 (264) Show / Hide 
Range on Protein: 1439-1479
Range on HMM: 222-264/264
Sequence Identity: 51% (22 aa)

IP--DHISPEAKNLLTQLLQVNPLERLGGGQSGADEVKAHPFF
.|  | ||||.|.|...||. .| .||||| ..|.|.|.||.|
FPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase RSKL.AA MAST 1441-1479 58 2.4e-19 55.18 In-house 301-337 (337) Show / Hide 
Range on Protein: 1441-1479
Range on HMM: 301-337/337
Sequence Identity: 58% (23 aa)

DHISPEAKNLLTQLLQVNPLERLGGGQSGADEVKAHPFF
| .||||. |  .|||.||..||| .  ||||.| ||||
DCMSPEAQDLIKKLLQPNPKKRLGAN--GADEIKQHPFF
Kinase RSKL.AA RSK-Unclassified 1387-1479 34 1.1e-17 51.58 In-house 185-283 (283) Show / Hide 
Range on Protein: 1387-1479
Range on HMM: 185-283/283
Sequence Identity: 34% (34 aa)

TNMYTAPEAGSIFGVGPACDWWSYGTILFELLTGQSLYSCHPSGIS----SHTQLFIP--DHISPEAKNLLTQLLQVNPLERLGGGQSGADEVKAHPFF
|  | |||     | . | |||  | ...|.| |   |    .          .. .|    || ... |.  ||| ||  ||| ..  ||..|.||||
TEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase RSKL.AA AktR 1431-1479 36 7.8e-17 61.53 In-house 217-268 (268) Show / Hide 
Range on Protein: 1431-1479
Range on HMM: 217-268/268
Sequence Identity: 36% (19 aa)

ISSHTQLFIPDH--ISPEAKNLLT-QLLQVNPLERLGGGQSGADEVKAHPFF
| ...|...|..  .|...|.|.. .||. || .||| . .|..|.| ||.|
IKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase RSKL.AA RSK 1439-1479 41 2.4e-16 56.58 In-house 236-278 (278) Show / Hide 
Range on Protein: 1439-1479
Range on HMM: 236-278/278
Sequence Identity: 41% (18 aa)

IP--DHISPEAKNLLTQLLQVNPLERLGGGQSGADEVKAHPFF
.|  . .|.|||.|....|...|  |||.| ..|.|.|.||.|
MPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase RSKL.AA RSK-Unclassified 1326-1371 52 1.5e-15 44.78 In-house 100-145 (283) Show / Hide 
Range on Protein: 1326-1371
Range on HMM: 100-145/283
Sequence Identity: 52% (24 aa)

ESCVRIWASEILFALATLHAAGIICRDLNPDNILLAEGGHIRLTYF
|  ||..|||.  ||  ||  ..| ||| ||||.|   ||..|| |
EDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDF
Kinase RSKL.AA RSK 1439-1479 46 1.7e-15 51.95 In-house 231-271 (271) Show / Hide 
Range on Protein: 1439-1479
Range on HMM: 231-271/271
Sequence Identity: 46% (19 aa)

IPDHISPEAKNLLTQLLQVNPLERLGGGQSGADEVKAHPFF
..| ||.||| ||...| ..|  ||| |  |. ..| ||.|
NWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase RSKL.AA Pkinase 1400-1479 19 9.9e-15 53.17 Pfam 188-293 (293) Show / Hide 
Range on Protein: 1400-1479
Range on HMM: 188-293/293
Sequence Identity: 19% (22 aa)

GVGPACDWWSYGTILFELLTGQSLYS------------CHPSGISSHTQLFIPDHIS-------------------PEAKNLLTQLLQVNPLERLGGGQS
. ||..|.||.| ||.|.|.|. ...            ..    .  .   .|  .|                   .|.| ... .|...| .|..    
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----

GADEVKAHPFF
 |.... ||.|
-AEQILQHPWF
Kinase RSKL.AA S_TKc 1258-1479 24 1.1e-12 8.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 1258-1479
Range on HMM: 1-231/231
Sequence Identity: 24% (63 aa)

EAMEDNIYGGEDGSVGEANTTP---------TNSRTSTLKGEHLGMQDTSLPSLSRLFSHLD----------------DVRRSRAESSAAT----LPESC
  . . |  |  |.|  .  .           .    ... |   ..    | . .|. . .                |...   .         .||  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

VRIWASEILFALATLHAAGIICRDLNPDNILLAEGGHIRLTYFSQWKWVCQEMNLKALTNMYTAPEAGSIFGVGP-ACDWWSYGTILFELLTGQSLYSCH
.| .. .|. ||. .|  ||| ||| |.|||| |  || .. |   . .    .    |  | |||     | |. .||||| | ||.|.|.|. ... .
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-Q

PSGISSHTQLFIPDHISPEAKNLLTQLLQVNPLERLGGGQSGADE--VKAHPFF
.  .  .         |||||... ..||..| .|..  .  .||  .|.||.|
MQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RSKL.AA RSK 1324-1369 38 1.3e-11 37.96 In-house 98-147 (271) Show / Hide 
Range on Protein: 1324-1369
Range on HMM: 98-147/271
Sequence Identity: 38% (19 aa)

LPESCVRIWASEILFALATLHAAGIICRDLNPDNILLAEG----GHIRLT
..|. |.. ..||. |.. ||  ||. ||| |.|||...     |||...
FSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKIC
Kinase RSKL.AA RSK 1324-1369 42 4.6e-11 37.04 In-house 101-149 (278) Show / Hide 
Range on Protein: 1324-1369
Range on HMM: 101-149/278
Sequence Identity: 42% (21 aa)

LPESCVRIWASEILFALATLHAAGIICRDLNPDNILLAE---GGHIRLT
. |. ... ..||  |.  ||  ||| ||| |.|||...    |||.||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLT
Kinase RSKL.AA MAST 1323-1369 42 1.6e-09 24.58 In-house 98-144 (337) Show / Hide 
Range on Protein: 1323-1369
Range on HMM: 98-144/337
Sequence Identity: 42% (20 aa)

TLPESCVRIWASEILFALATLHAAGIICRDLNPDNILLAEGGHIRLT
..||. ...   |.  .|  ||  ||. ||| |||.|.   ||| ||
CMPEWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLT
Kinase RSKL.AA AktR 1326-1369 48 4.1e-09 31.6 In-house 100-144 (268) Show / Hide 
Range on Protein: 1326-1369
Range on HMM: 100-144/268
Sequence Identity: 48% (22 aa)

ESCVRIWASEILFALATLHAA-GIICRDLNPDNILLAEGGHIRLT
|. .|. ...|| || .||    || ||| |.|||| | ||...|
EEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKIT
Kinase RSKL.AA Akt 1319-1369 40 8.8e-09 24.11 In-house 92-143 (264) Show / Hide 
Range on Protein: 1319-1369
Range on HMM: 92-143/264
Sequence Identity: 40% (21 aa)

SSAATLPESCVRIWASEILFALATLHAAGIICRD-LNPDNILLAEGGHIRLT
. . . .|.  |  ..||  |.  ||  .|| || | | |||. . |||.||
QRKRRFSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLT
Kinase RSKL.AA RSK 1402-1422 52 2.4e-07 23.32 In-house 190-210 (278) Show / Hide 
Range on Protein: 1402-1422
Range on HMM: 190-210/278
Sequence Identity: 52% (11 aa)

GPACDWWSYGTILFELLTGQS
. |||||| | ...|.|||..
DKACDWWSLGVLMYEMLTGCP
Kinase RSKL.AA MAST 1400-1420 50 5e-06 13.71 In-house 244-265 (337) Show / Hide 
Range on Protein: 1400-1420
Range on HMM: 244-265/337
Sequence Identity: 50% (11 aa)

G-VGPACDWWSYGTILFELLTG
|  |.. |||| | |..|.|.|
GTYGKPVDWWSMGIIMYEFLVG
Kinase RSKL.AA RSK 1404-1420 64 6e-06 17.47 In-house 185-201 (271) Show / Hide 
Range on Protein: 1404-1420
Range on HMM: 185-201/271
Sequence Identity: 64% (11 aa)

ACDWWSYGTILFELLTG
||||||.|....| |||
ACDWWSFGVLMYEMLTG
Kinase RSKL.AA Akt 1404-1421 36 2.9e-05 12.68 In-house 182-200 (264) Show / Hide 
Range on Protein: 1404-1421
Range on HMM: 182-200/264
Sequence Identity: 36% (7 aa)

ACDWWS-YGTILFELLTGQ
|.|||.  | ...|...|.
AVDWWGSLGCVMYEMMCGR
Kinase RSKL.AA Pkinase 1332-1369 40 0.000485 15.37 Pfam 113-154 (293) Show / Hide 
Range on Protein: 1332-1369
Range on HMM: 113-154/293
Sequence Identity: 40% (17 aa)

WASEILFALATLHAAGIICRDLNPDNILLAEGGHI----RLT
.. .|| .|. .|. ||| ||| |.|||. . |||    ...
YMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKIC
Kinase RSKL.AA TyrKc 1258-1479 15 0.000912 -161.73 SMART 1-280 (280) Show / Hide 
Range on Protein: 1258-1479
Range on HMM: 1-280/280
Sequence Identity: 15% (45 aa)

EAMEDNIYGGEDGSV--GEANTTPTNSRTS----TLKGEHLGMQD--------TSL------------------------PSLSRLFSH-----LDDVRR
  ... .  |. | |  |...       .     .|| ..  ..|        ..|                        . |  .. .     |.|  |
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SRAESSAATLPESCVRIWASEILFALATLHAAGIICRDLNPDNILLAEGGHIRLTYF--SQWKWVC-------QEMNLKA--LTNM-----YTAPEAGSI
.. .     |. .    ..  |    . ||  ..| |||   |.|..|..... . |  |             .    |    ...      .|||.   
KHRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

FGVGPACDWWSYGTILFELLT-GQSLYS------CHPSGISSHTQLF----IPDH--------ISPEAKNLLTQLLQVNPLERLGGGQSGADEVKAHPFF
    .. | ||.|  ..|..| ||. |.      . .. .  . .      .|..         ..|  .. .|  . .| .|    .        | .|
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-------HECF
Kinase RSKL.AA AktR 1404-1421 38 0.001542 9.99 In-house 185-202 (268) Show / Hide 
Range on Protein: 1404-1421
Range on HMM: 185-202/268
Sequence Identity: 38% (7 aa)

ACDWWSYGTILFELLTGQ
..|||. |. ..|..||.
SVDWWAFGIFIYEMVTGC
Kinase RSKL.AA AGC 546-577 17 0.016691 0.69 In-house 89-133 (395) Show / Hide 
Range on Protein: 546-577
Range on HMM: 89-133/395
Sequence Identity: 17% (8 aa)

CPYMVR-LYRYFETESS--IFLLLE----HAT-----GG-KLWNY
.|. |. |.  |....   .....|     .      ||  |. .
HPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLH
Kinase RSKL.AA RSK-Unclassified 547-574 35 0.029482 2.31 In-house 59-86 (283) Show / Hide 
Range on Protein: 547-574
Range on HMM: 59-86/283
Sequence Identity: 35% (10 aa)

PYMVRLYRYFETESSIFLLLEHATGGKL
|. |.||  | |.   .| .|   || .
PFIVTLYHSFQTQDYLYLCMEYCMGGDF
Kinase RSKL.AA Pkinase 546-577 36 0.045067 8.41 Pfam 59-94 (293) Show / Hide 
Range on Protein: 546-577
Range on HMM: 59-94/293
Sequence Identity: 36% (13 aa)

CPYMVRLYRYFETESSIFLLLEHATGG----KLWNY
.|. ||||..||....| . .|.. ||     |. |
HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY
Kinase RSKL.AA AktR 547-577 32 0.109142 2.82 In-house 61-91 (268) Show / Hide 
Range on Protein: 547-577
Range on HMM: 61-91/268
Sequence Identity: 32% (10 aa)

PYMVRLYRYFETESSIFLLLEHATGGKLWNY
| .|.|.  |.|.. .|...|   ||.| ..
PFIVKLHYCFQTKEKLFFIMEYCPGGELFQH
Kinase RSKL.AA RSK 547-574 28 0.238509 0.87 In-house 61-88 (271) Show / Hide 
Range on Protein: 547-574
Range on HMM: 61-88/271
Sequence Identity: 28% (8 aa)

PYMVRLYRYFETESSIFLLLEHATGGKL
|. |.|.  |..| .... .. . || |
PFIVKLHYVFQDEGKVYMIMDFMRGGDL
Kinase RSKL.AA RSK 546-572 37 0.299352 0.78 In-house 60-86 (278) Show / Hide 
Range on Protein: 546-572
Range on HMM: 60-86/278
Sequence Identity: 37% (10 aa)

CPYMVRLYRYFETESSIFLLLEHATGG
.|  |.|.  |.||. ..| .|   ||
HPFIVTLHYAFQTEGKLYLIMEYCRGG