Gene AMPK (Sea Urchin)

AMPK

Species: Sea Urchin
Alias: AMPK, Spk097, SPU_010280
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
AMPK.AA Protein None 548 None Fasta, JSON
AMPK.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of AMPK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AMPK.AA AMPK 13-266 74 5.1e-230 689.97 In-house 1-254 (254) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-254/254
Sequence Identity: 74% (190 aa)

YVLGETIGMGTFGKVKMGEHLLTQHKVAIKILNRQKIKNLDVVSKIKREIQNMKLFRHPHIVKLYQVI-STPTDIFMVMEYVAGGELFDYIVKHGKLKEH
|..|.|||.|||||||||.| ||..||||||||.||||..|.| .|.|||...||||||||..||.|| .||||||||||||.||||||||||||.|.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNLHVKIADFGLSNMMTDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPF
||.||||||||||.|||||||||||||||||||| | ..||.||||||||.|||||.|.||||.|||||.||||||.|||||||||||||||.|||.|||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DDEHVPTLFRKIKGGHFTIPDHIERSQVKSLIQHMLQVDPLKRATIKDIREHDWF
|||..|||..||| |...||..... ..|.||.|||||||.||.||.|||.|.||
DDENTPTLYKKIKNGEYYIPKFLSP-EAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase AMPK.AA CAMKL 13-266 48 1.2e-167 539.18 In-house 1-297 (297) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-297/297
Sequence Identity: 48% (145 aa)

YVLGETIGMGTFGKVKMGEH-LLTQHKVAIKILNRQKIKN-------------LDVVSKIKREIQNMKLFR---HPHIVKLYQVI-------STPTDIFM
| .|.|.| |.|||||...| ..|..||||||....||.|             .... .|.|||| ||...   ||.|.|||.||       .| ..|..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYL

VMEYVAGGE--LFDYIVKH----GKLKEHEARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNL--HVKIADFGLSNMMTD-----GEFLRTSCGSPN
||||. |||  ||||||||    |...||||||.|.||.|.|.|||.|.|||||.||||.||| |    .||.|||.|||...     |..|.|.||||.
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YAAPEVISG--KLYAGPEVDIWSCGVILYALLCGTLPFDDE--------HVPTLFRKIKGGHFTIPDHIERSQVKSLIQHMLQVDPLKRATIKDIREHDW
|.|||...|  | | ||.||||||||||||..||.|||||.        .. .|..||..| . .| ... |....||..||||.| ||.||..|..| |
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M
Kinase AMPK.AA CAMK 18-266 30 3.3e-139 451.55 In-house 1-425 (425) Show / Hide 
Range on Protein: 18-266
Range on HMM: 1-425/425
Sequence Identity: 30% (131 aa)

TIGMGTFGKVKMGEHLLTQ------------HKVAIKILNRQKIKN-------------------------LDVVSKIKREIQNMKL-------FRHPHI
|.| |.||||| ..| .|.            .||||||....|.|.                              ...|||. ||.        .||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLYQVIS------------TPTD--------IFMVM---EYVAGGEL----FDYIVKH---------------GKLKEHEARRFFQQIISGVDYCHRHM
.|||.|.             | ..        ..|||   ||. ||||    |||||.|               |...|.||||.|.||.|.|.||| | 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPENLLLDPN-----------------LHVKIADFGLSNMMTD------------------------GEFLRTSCGSPNYAA-PEVISG-----
||||||||||.||| |                   .||.|||..|....                        |. ..|.||.| |.| |||..|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KLYAGPEVDIWSCGVILYALLCGTLPFDDE-------------HVPTLFRKIKGGHFT-IPDHIERSQ----------------------VK
        | | ||..|.||||||||..|||..||...             . . ||.||. | .. .|...  .                       .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

SLIQHMLQVDPLKRATIKDIREHDWF
.||..|||||| ||.||... .| |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AMPK.AA NuaK 13-266 48 5.6e-133 352.13 In-house 1-252 (252) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-252/252
Sequence Identity: 48% (124 aa)

YVLGETIGMGTFGKVKMGEHLLTQHKVAIKILNRQKIKNLDVVSKIKREIQNMKLFRHPHIVKLYQVISTPTDIFMVMEYVAGGELFDYIVKHGKLKEHE
| . .| | ||.|||| .    |  .||||   ..||.      .| |||. |    ||||.. | |      | .|||| .||||.||| . ..| |.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNLHVKIADFGLSNMMTDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFD
||.|| ||.| | |||.| |.||||| || ||| |  .|||||||||.  |..|| | |||| || ||.. |. | ||||| || ||.||..  ||.|||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

DEHVPTLFRKIKGGHFTIPDHIERSQVKSLIQHMLQVDPLKRATIKDIREHDWF
 .   .| . |. |..  |   . |.   || .||.|.| .|||| || .| | 
GHDFKHLVKQISQGAYYEPC--KPSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase AMPK.AA MARK 13-266 46 1.7e-128 422.03 In-house 1-262 (262) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-262/262
Sequence Identity: 46% (122 aa)

YVLGETIGMGTFGKVKMGEHLLTQHKVAIKILNRQKIKNLDVVSKIKREIQNMKLFRHPHIVKLYQVIS--TPTD-IFMVMEYVAGGELFDYIVKH--GK
| .. ||| |...||| . |..|. ||||||....|.      ....|||. ||.  ||.|.||..||   |..  |...|||. ||||.|||..|  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LKEHEARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNL--HVKIADFGLSNMMTDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALL
|.| ||||.|.||.|.| |||...|||||.||||.|.| |    .||.|||.|.  . |. | | ||.| |.|||....| | ||.|||||.||.||...
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

CGTLPFDDEH--VPTLFRKIKGGHFTIPDHIERSQVKSLIQHMLQVDPLKRATIKDIREHDWF
||..|||.      .|..||  |...||.|. . . ..||| .|.|.| .|.||..| .| |.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSK-ECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase AMPK.AA BRSK 13-266 50 7.2e-120 404.53 In-house 1-254 (254) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-254/254
Sequence Identity: 50% (129 aa)

YVLGETIGMGTFGKVKMGEHLLTQHKVAIKILNRQKIK-NLDVVSKIKREIQNMKLFRHPHIVKLYQVISTPTDIFMVMEYVAGGELFDYIVKHGKLKEH
| |. | | |. |.||.| |  |  |||||| |. |      .  |. |||  |||  |||. |.| |  .    ....|.|.||||||| || |.|.  
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNLHVKIADFGLSNMMTDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPF
|||.||.||||..|.|| | | ||||||||||||    .||||||.  .  ..  | |||||| || ||||.|  | |   |.||||||||||| | |||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DDEHVPTLFRKIKGGHFTIPDHIERSQVKSLIQHMLQVDPLKRATIKDIREHDWF
||. .  |  |.| | | .|  |    . .|   |. ||| || ..|.|..| |.
DDDNLRQLLEKVKRGVFHMPHFIHP-DCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase AMPK.AA QIK 13-266 47 2.3e-118 399.5 In-house 1-272 (272) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-272/272
Sequence Identity: 47% (129 aa)

YVLGETIGMGTFGKVKMGEHLLTQHKVAIKILNRQKIKNLDVVSKIKREIQNMKLFRHPHIVKLYQVISTPTDIFMVMEYVAGGELFDYIVKHGK-----
| .. ||| | |. ||.. |  |  ||||||. . .. . .   |..||.| ||. .||||.|||||. |   ...|.||  .||.|||..|||.     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LKEHEARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNLHVKIADFGLSNMMTDGEFLRTSCGSPNYAAPEVISGKLYAGPEV
               ..| |||| |.||.|.|.|||.. ||||||| ||.||| |. .||||||.||  . |. | | |||| |||||.  || | ||.|
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DIWSCGVILYALLCGTLPFDDEHVPTLFRKIKGGHFTIPDHIERSQVKSLIQHMLQVDPLKRATIKDIREHDWF
|||| ||.||.| || |||| . ...| ...  | | ||  .  .   .|| ||| ||| .| ||. |..| | 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMS-QDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase AMPK.AA S_TKc 13-266 40 4.3e-109 369.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-231/231
Sequence Identity: 40% (109 aa)

YVLGETIGMGTFGKVKMGEHLLTQHKVAIKILNRQKIKNLDVVSKIKREIQNMKLFRHPHIVKLYQVISTPTDIFMVMEYVAG--GELFDYIVKHGK---
| ....|| |.||||. . |  |...|||||..           .|.|||| .|  .||.||||| |. . ....|||||. |  |.|||||.|.|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LKEHEARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNLHVKIADFGLSNMMTDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYAL
   . | .||....||.....|||.| |.||||||||.|||   |.||.||||.  .      .| ||.|.| ||||.    | ....|.||||.||| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LCGTLPFDDEHVPTLFRKIKGGHFTIPDHIERSQVKSLIQHMLQVDPLKRATIKDIRE-------HDWF
|||  ||.  .. ..|.||.            ...|..|...||.|| || |. .. .       | ||
LCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AMPK.AA CAMK1 13-266 40 4.5e-106 309.34 In-house 1-276 (276) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-276/276
Sequence Identity: 40% (113 aa)

YVLGETIGMGTFGKVKMGEHLLT---QHKVAIKILN-RQKIKNLDVV--SKIKREIQNMKLF---RHPHIVKLYQVISTPTDIFMVMEYVAGGELFDYIV
|..|..|| |.|..|. ..|  |   ....|||... .. .|. |.    ....||. || .    ||.|.|.| .  ..... .|||.| |||||| ||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

KHGKLKEHEARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPN---LHVK--IADFGLSNMMTDGE-FLRTSCGSPNYAAPEVISG---KLYAGPEVDI
. |.  | .||.  .||.| | |.| . ||||||||||||. ..     .|  ||||||| .  ..| .. | ||.| | ||||. .   | | . ..|.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPY-DKACDM

WSCGVILYALLCGTLPFDDEH-VPTLFRKIKGGHFTIP----DHIERSQVKSLIQHMLQVDPLKRATIKDIREHDWF
||.|||.| ||||  || ||   ..||.||| . .. |    |.|  ...| .| ||| ||| || |.... .| |.
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase AMPK.AA Pkinase 13-266 37 9.60000000001e-104 355.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-293/293
Sequence Identity: 37% (110 aa)

YVLGETIGMGTFGKVKMGEHLLTQHKVAIKILNRQKIKNLDVVSKIK-REIQNMKLFRHPHIVKLYQVISTPTDIFMVMEYVAGG----ELFDYIV--KH
|..|..|| |.||.|. . |  |...||.||......|    ..... .||| || ..||.||.|| .  ....| |||||. ||    .|||||   .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKL--KEHEARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNLHV----KIADFGLSNM--MTDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSC
|..   |.|..... ||..|..|||.. |.||||||||.|.| | |.    ||.||||.       .. . | ||.|.|.||||| |  | ||.||.|||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYALLCGTLPFDDE------HVPTLFRKIKGGHFTIPDHIER--------------------SQVKSLIQHMLQVDPLKRATIKDIREHDWF
|.||| .||| .||...          ....|.|. .  .   ..                    .  |..|  .|..|| || |...| .|.||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AMPK.AA MELK 13-266 46 3.6e-97 329.13 In-house 1-254 (254) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-254/254
Sequence Identity: 46% (119 aa)

YVLGETIGMGTFGKVKMGEHLLTQHKVAIKILNRQKIKNLDVVSKIKREIQNMKLFRHPHIVKLYQVISTPTDIFMVMEYVAGGELFDYIVKHGKLKEHE
| . ..|| | |.|||.  |.||...|||||...... .   . ..| |.. .| .|| || .|| .| |   ||||||| .|||.||||... .|.|.|
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGH--DLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

ARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNLHVKIADFGLSNMM---TDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTL
.| ||.||.| . | |     ||||||||||.| ..|.|. ||||        |   | | |||| |||||.|.|| | | | |.|| |..||.|.|| |
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PFDDEHVPTLFRKIKGGHFTIPDHIERSQVKSLIQHMLQVDPLKRATIKDIREHDWF
||||. .  ...||  | .  |...   . | |..||||||| ||  .|.. .|.| 
PFDDDNMMIMYKKIMSGCYEEPKWLS-PESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase AMPK.AA GIN4 58-266 50 5.3e-93 297.41 In-house 81-293 (293) Show / Hide 
Range on Protein: 58-266
Range on HMM: 81-293/293
Sequence Identity: 50% (108 aa)

IKREIQNMKLFRHPHIVKLYQVISTPTDIFMVMEYVAGGELFDYIVKHGKLKEHEARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNLH-VKIADFG
| |||  |||  || ...||.|  | .|...|.||. .||||.|.|.||.| |.|| ..|.||| || |||   |.||||||||||||   . .||||||
IEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFG

LSNMMTDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDE--HVPTLFRKIKGGHFTIPDHIERSQ-VKSLIQHMLQVDPLK
.  . ||.. |.|||||| |||||...|  | |   |.|||||||.||| | ||||.|   . .|  |.. |.. .|.  | |.  . ||. .| ||| |
MAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEK

RATIKDIREHDWF
| ...|| .|   
RIKTRDILKHPLI
Kinase AMPK.AA Pkinase_Tyr 13-158 33 3.3e-28 96.15 Pfam 1-158 (270) Show / Hide 
Range on Protein: 13-158
Range on HMM: 1-158/270
Sequence Identity: 33% (53 aa)

YVLGETIGMGTFGKVKMGEHL----LTQHKVAIKILNRQKIKN-LDVVSKIKREIQNMKLF-RHPHIVKLYQVISTPTD---IFMVMEYVAGGELFDYIV
 ..|...| | ||.|..|.       |. .||.|.|. .  .  .    .  ||.. || . .||.||.|| |..   .   |..||||...| | ||  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KH----GKLKEHEARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNLHVKIADFGLS
||    ..|. ..   . .|| .| .| ... ..||||   | |.. |..|||.||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase AMPK.AA TyrKc 13-266 26 1.3e-23 85.73 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

YVLGETIGMGTFGKVKMGEHLLTQHKVAIKILNRQKIKNLDVVSKIKREIQNMKLF--RHPHIVKLYQVISTP-------TDIFMVMEYVAGGELFDYIV
 .||...| | ||.|  |.      .||.| |.  .      .  . ||.. |. .  .||.||.|| |....         ...||||...| | ||. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KHGK-LKEHEARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDPNLHVKIADFGLSNMMTDG-------EFLRTSC--GSP-----NYAAPEVISGKLYA
||.. |.  .   |  || .| .| |.. ..||||   | |.. |..|||.|||||   .|.       .  |..   |.         |||.|  . . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-

GPEVDIWSCGVILYALL-CGTLPFDD-----EHVPTLFRKIKGGHFTIPDHI--------ERSQVKSLIQHMLQVDPLKRATIKDIREHDWF
 .. |.|| || .. ..  |  |  .          .....| |.   . .           . . ....   . || .| | ..|  |. |
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase AMPK.AA GIN4 13-49 37 3.9e-08 21.65 In-house 1-37 (293) Show / Hide 
Range on Protein: 13-49
Range on HMM: 1-37/293
Sequence Identity: 37% (14 aa)

YVLGETIGMGTFGKVKMGEHLLTQHKVAIKILNRQKI
. ||||.|.|  |||..  .  | .. |.|.. ..||
WKLGETLGFGSTGKVQLAKNMETGQRAAVKVISKKKI
UBA_CAMKL AMPK.AA UBA_CAMKL 286-325 21 1.8e-07 25.14 In-house 1-41 (41) Show / Hide 
Range on Protein: 286-325
Range on HMM: 1-41/41
Sequence Identity: 21% (9 aa)

DVDAVKEVCEKF-NVREGEVQNALMCGDPHDQLRIAYYLII
| ....|.|... .. . |. ..|  ...|......|||..
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL