Gene MARK4 (Sea Urchin)

MARK4

Species: Sea Urchin
Alias: MARK4, SPU_010156, Spk103
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
MARK4.AA Protein None 302 None Fasta, JSON
MARK4.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of MARK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MARK4.AA MARK 10-294 26 3.6e-96 314.85 In-house 1-259 (262) Show / Hide 
Range on Protein: 10-294
Range on HMM: 1-259/262
Sequence Identity: 26% (81 aa)

SEPVVILGKGRQCVVKLATSTRYQTPRKVAIKINL---PSR-----SSARESEILFKLNHENVVEIFDYFVFQDHS----YIVLALAENGDMRNFVRQR-
 . .  .|.|  ..||||......  |||||||      ..     .  || ||. ||.|.|... |.... ||..    |... .|..|......... 
YKMLKTIGHGSYAKVKLACHKHTG--RKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIE-QDTEQHQIYLIMEYASGGELYDYIKAHP

-GRLGEALALKMCEQIFEGVAYLHDTASVAHCDLKCENVLVDERE--DVKIADFGLAVEIAVGSNGTSQPRRTSNSRNHGDSQNGVSDSCSSRAVSISPI
 ||| | .| ... || ..| |.|.   ..|.|.|.||.|.||.   ..||.|||....|  |.                                    
NGRLHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK-----------------------------------

PQGIASLGGSPAYAAPEVLDSRVTDLRAADVWSAGVITFFILTTYLPFG--CYGNKNIREAMNRPLRWPRPLKQVKKSDRTFVQSALVLKPSERPTARAL
     .  |.|.|.|||.. ..  | ...|.|| ||. .|... |.||   ....|.... ..|.  . .| . | |. | ..|. |.. |.||||.  .
---LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYD-IPCH-VSKECRNLIQRLLTVNPEERPTIEEI

LER
...
MKH
Kinase MARK4.AA CAMKL 16-293 23 3.3e-74 236.19 In-house 7-293 (297) Show / Hide 
Range on Protein: 16-293
Range on HMM: 7-293/297
Sequence Identity: 23% (77 aa)

LGKGRQCVVKLATSTRYQTPRKVAIKINLPSRSSA--------------------RESEILFKLN---HENVVEIFDYFVFQDH------SYIVLALAEN
||||   .||||| .|..  .||||||   .. .                     || .|. .||   |.|.. ... .  ..|       |.|. ....
LGKGSFGKVKLATHIRTT-GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSG

GD--MRNFVRQR----GRLGEALALKMCEQIFEGVAYLHDTASVAHCDLKCENVLVDERED--VKIADFGLAVEIA-VGSNGTSQPRRTSNSRNHGDSQN
|.  . ......    ||. |  | ..  || ..|.|.|.   ..| |.| ||.|.||. .  .||.|||.. ..  .                      
GEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC----------------------

GVSDSCSSRAVSISPIPQGIASLGGSPAYAAPEVLDS--RVTDLRAADVWSAGVITFFILTTYLPFGCYGNK-------NIREAMNRPLRWPRPLKQVKK
            | .  |      |||.|.|||.. .  .  | ...|.||.||| ..... |||| .  ..       . ..  ..   .|.. ..|  
------------IFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-

SDRTFVQSALVLKPSERPTARALLE
. | . .. |. .|..|||.  ...
DCRDLIRKMLQVNPEKRPTIHQIMN
Kinase MARK4.AA CAMK 15-293 17 5.7e-58 185.05 In-house 1-421 (425) Show / Hide 
Range on Protein: 15-293
Range on HMM: 1-421/425
Sequence Identity: 17% (76 aa)

ILGKGRQCVVKLATSTRYQT----------PRKVAIKI--------------------------------NLPSRS-SARESEILFK-------LNHENV
.||.|. ..|||.. .. .           ..||||||                                .  .|    || ||. |       |.|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VEIFDYFV------------FQDH--------SYIVL---ALAENG----DMRNFVRQR---------------GRLGEALALKMCEQIFEGVAYLHDTA
. .....             . ..         |.|.    ....|    |. ......               ||. |. | ..  || ..|.|.|.  
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

SVAHCDLKCENVLVDERE-----------------DVKIADFGLAVEIAV---------GSNGTSQPRRTSNSRNHGDSQNGVSDSCSSRAVSISPIPQG
 ..|.|||.||.|.|...                 ..||.|||.| ..           . .|. . ..                     .....   | 
-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN---------------------QWTTPTEGQK

IASLGGSPAYAA-PEVLDS-------------RVTDLRAADVWSAGVITFFILTTYLPFGCYGNKNIRE------------AMNRPLRWPRPLKQVKK--
     |.|.|.| |||| .             .  . ...|.||.|||... |. |.||    ...|.|             . .  ..  | .....  
MKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPIS

---------------------SDRTFVQSALVLKPSERPTARALLE
                     . . .... |.  |..|.|.   |.
CNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLN
Kinase MARK4.AA S_TKc 10-298 25 1.8e-54 188.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-298
Range on HMM: 1-231/231
Sequence Identity: 25% (78 aa)

SEPVVILGKGRQCVVKLATSTRYQTPRKVAIKINLPSRSSARESEILFKLNHENVVEIFDYFVFQDHSYIVLALAEN--GDMRNFVRQRGR------LGE
 | . ..|||   .|.... ..  | |.|||||    ..  || .|| | .|.|.| ..|.|.  || |.|. ....  ||.. . ..|||      . |
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

ALALKMCEQIFEGVAYLHDTASVAHCDLKCENVLVDEREDVKIADFGLAVEIAVGSNGTSQPRRTSNSRNHGDSQNGVSDSCSSRAVSISPIPQGIASLG
  | ... ||.....|.|.   . |.||| ||.|.||   .||.||||| ..                                             .. 
-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------------------------------------------TTFC

GSPAYAAPEVLDSRVTDLRAADVWSAGVITFFILTTYLPFGCYGNKNIREAMNRPLRWPRPLKQVKKSDRTFVQSALVLKPSERPTARALLE------RL
|.| | |||||     . ...|.|| |.| .  |. | ||      .. . ... .          .. . |..  |.  |..||||  .|.        
GTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

QRM
. .
PWF
Kinase MARK4.AA Pkinase 10-295 21 8.3e-46 163.05 Pfam 1-293 (293) Show / Hide 
Range on Protein: 10-295
Range on HMM: 1-293/293
Sequence Identity: 21% (73 aa)

SEPVVILGKGRQCVVKLATSTRYQTPRKVAIKINLPSRSSA---------RESEILFKLNHENVVEIFDYFVFQDHSYIVLALAENG----DMRNFVR--
 . . ..|.|   .|....   ..   .||.||   .. .          .| .|. .|||.|.|...|.|   || |.|. ..|.|    |   ...  
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

QRGRL--GEALALKMCEQIFEGVAYLHDTASVAHCDLKCENVLVDEREDV----KIADFGLAVEIAVGSNGTSQPRRTSNSRNHGDSQNGVSDSCSSRAV
..|..   |  . ... ||..|..|.|.  .. |.||| ||.|.|.. ..    ||.|||||  .                                   
RHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------------------------------

SISPIPQGIASLGGSPAYAAPEVLDSRVTDLRAADVWSAGVITFFILTTYLPFG-C------YGNKNIREAMNRPLRWPRPLK-----------------
      .   .. |.| |.||||. ..  . ...|.||.|.| .  |. ..||  .        .. |.. | .||....| .                 
--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF

-QVKKSDRTFVQSALVLKPSERPTARALLER--L
  . .. . |. . | ..|..||||. .|.   .
HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MARK4.AA Ciliate-E2-Unclassified 10-244 18 1.4e-31 106.8 In-house 1-273 (352) Show / Hide 
Range on Protein: 10-244
Range on HMM: 1-273/352
Sequence Identity: 18% (56 aa)

SEPVVILGKGRQCVVKLATSTRYQTPRKVAIKINLPSRSSA-----------RESEILFKLNHENVVE------------------IFDYFVF--QDHSY
 . . ..|.| ...|...   . ..  . |.|..  ... .           .| ........ ....                  . ....|  ... |
YKIIKQIGQGGFGKVYKC--QHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

IVLALAENGDMRNFVRQR-----------------GRLGEALAL-----KMCEQIFEGVAYLHDTASVAHCDLKCENVLVDERE---DVKIADFGLAVEI
||. ..|.||.... ..|                  .. |  |.     ... || .|  |||    . | |.|.||.|.|.      .||.|||.. ..
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

A--VGSNGTSQPRRTSNSRNHGDSQNGVSDSCSSRAVSISPIPQGIASLGGSPAYA----APEVLDSRVTDLR---AADVWSAGVITFFILTTYLPFGCY
   ...  |.|                       ..    ...| . .  |.| |     |||||..   | .   ..|.|| ||| ...|. |.||...
QQNNNCD-TNQ-----------------------QQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDN
Kinase MARK4.AA Ciliate-E2 10-293 15 1.2e-30 102.36 In-house 1-361 (365) Show / Hide 
Range on Protein: 10-293
Range on HMM: 1-361/365
Sequence Identity: 15% (60 aa)

SEPVVILGKGRQCVVKLA--TSTRYQ-----------------------TPRKVAIKINLPSRSSARESE--------------ILFKLNHENVVEIFDY
 . . ..|.| . .|...   ....|                          |. .| .. . ..                   ||..||| |.......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FV--FQDHSYIVLALAENGDMRNFVRQR-----------GRLGEALALKMCEQIFE---------------GVAYLHDTASVAHCDLKCENVLVDEREDV
|    ... |.|. ... ||.. . ...           ... |  .... .||..               .. |||   .. | |.| ||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGLAVEIAVGSNGTSQPRRTSNSRNHGDSQNGVSDSCSSRAVSISPIPQ-----GIASLGGSPAYAAPEVLDS--------RVTDLRAADVWSAGV
||.||||. ..   .. ...  . ..      ... .. ....         |      . .. |.| | |||.| .        .     ..|.||.||
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMD---------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGV

ITFFILTTYLPFGCYGNKNIREAMNRPLRWPRPL---------------KQVKKSDRTFVQS----ALVLKPSERPT-ARALLE
| .. |. ..||       ... .. ... | |                |.. ..   . .      |. .|..|.| .  .|.
ILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase MARK4.AA RAD53 7-150 31 7e-28 79.7 In-house 1-174 (305) Show / Hide 
Range on Protein: 7-150
Range on HMM: 1-174/305
Sequence Identity: 31% (56 aa)

YVLSEPVVILGKGRQCVVKLATSTRYQTPRKVAIKINLPSR-----SSA--------RESEILFKLNHENVVEIFDYFVF-QDHSYIVLALAENGDMRNF
|..|.   .||.|   .||||  ..  | .||||||   ..     ...        .| ||| ||||.....|.| |.  |. .|.|| |...|.  |.
YYMSK---ELGSGNFGTVKLAYEKK--TCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNK

VRQRGR----LGEALALKMCEQIFEGVAYLHDTASVAHCDLKCENVLVD-EREDV-----------------KIADFGLA
.  ..|    ..|. .   . |. ..| ||||    .| ||| ||.| .  .|..                 ||.||||.
IVSNKRCQMGFDEDTCKYYFYQMCDAVKYLHDNG-ICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLS
Kinase MARK4.AA TSSK 51-148 35 8.2e-28 88.35 In-house 64-168 (289) Show / Hide 
Range on Protein: 51-148
Range on HMM: 64-168/289
Sequence Identity: 35% (38 aa)

RESEILFK-LNHENVVEIFDYFVFQD-HSYIVLALAENGDMRNFVRQR------GRLGEALALKMCEQIFEGVAYLHDTASVAHCDLKCENVLVDEREDV
|| .|. | |.|.|.....  | ... . |.|. .||.||.  ... |      |.| | .| |.  |. ..|.|.|.   |.| ||||||.| |... .
REIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHS-HNVVHRDLKCENILLDKHWNI

KIADFG
|..|||
KLTDFG
Kinase MARK4.AA TKL 16-295 15 1e-27 96.9 In-house 1-364 (364) Show / Hide 
Range on Protein: 16-295
Range on HMM: 1-364/364
Sequence Identity: 15% (63 aa)

LGKGRQCVVKLATSTRYQTPR---------KVAIKINLPSRSSARES-------------------------E-------ILFKLNHENVVEIFDYFVFQ
.|.|. ..|  .   ...  .          ||.|.     .. ...                         .       .. .|.|.|.| .  |    
IGSGGFGEVYKG---KWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCP

DH-------------SYIVLALAENGDMRNFVRQRGRLGEALALKMCEQIFEGVAYLHDTA-------SVAHCDLKCENVLVDERED-------------
..              .||  ....|. ....         . .... .|  |..|||           ..|.||| .|.||||                
PCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-VKIADFGLAVEIAVGSNGTSQPRRTSNSRNHGDSQNGVSDSCSSRAVSISPIPQGIAS---------LGGSPAYAAPEVLDSRVTDLRAA---------
 .||.||||. ..   .| . .   . .|.                       .    .          .|.|.. |||||.    .  ..         
CCKICDFGLSRFMSQSGNMNDTMTTMMESA-----------------------E----HQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGF

------DVWSAGVITFFILTTYLPFGCYGN-------------KNIREAMNRPLRWPRPL--------KQVKKSDRTFVQSALVLKPSERPTARALLERL
      ||.| |.. . |||  .|. .|..             . . .  .||.. |...        ... .| .   |     .|..||..  .|.||
EYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MARK4.AA GIN4 51-150 38 2.1e-22 67.97 In-house 83-182 (293) Show / Hide 
Range on Protein: 51-150
Range on HMM: 83-182/293
Sequence Identity: 38% (39 aa)

RESEILFKLNHENVVEIFDYFVFQDHSYIVLALAENGDMRNFVRQRGRLGEALALKMCEQIFEGVAYLHDTASVAHCDLKCENVLVDERED-VKIADFGL
||  |.  ..| ||....| .  .   |.||  || |.. |.. ..|.| |  |...  || .||.| | .  . | ||| ||.|.|..   .||||||.
REIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCH-AFNICHRDLKPENLLLDHKYNRIKIADFGM

A
|
A
Kinase MARK4.AA AMPK 50-149 31 1.8e-21 60.56 In-house 47-146 (254) Show / Hide 
Range on Protein: 50-149
Range on HMM: 47-146/254
Sequence Identity: 31% (32 aa)

ARESEILFKLNHENVVEIFDYF-VFQDHSYIVLALAENGDMRNFVRQRGRLGEALALKMCEQIFEGVAYLHDTASVAHCDLKCENVLVDEREDVKIADFG
.|| .|| ...| ...  ..     ..  ..|.  . .|.   .. ..||| |  | .   ||  || |.|.   ..| ||| ||.| |.   .||.|||
QREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHM-IVHRDLKPENLLLDHNKNIKIVDFG

L
|
L
Kinase MARK4.AA TyrKc 7-295 22 1.8e-13 -4.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-295
Range on HMM: 1-280/280
Sequence Identity: 22% (72 aa)

YVLSEPVVILGKGRQCVVKLATSTRYQTPRKVAIKINLPSRSSA---RESEILFKL--NHENVVEIFDYFVFQ-------DHSYIVLALAENGDMRNFVR
 .| .   .|| |  ..| ..| .     ..||.|   ..   .   || .|. ||  .|.|.| .. . . |       .  .||. ....|| ... |
ITLGK---KLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QRGR-LGEALALKMCEQIFEGVAYLHDTASVAHCDLKCENVLVDEREDVKIADFGLAVEIAVG-SNGTSQPRRTSNSRNHGDSQNGVSDSCSSRAVSI--
 ... |  .  |..| || .| .|||.   . | || . |.||.|.  |||.||||. .|  . ..|                 ..   . ...  .   
KHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG----------------ESKDYYRKKEHKGGKTM

SPIPQGIASLGGSPAYAAPEVLDSRVTDLRAADVWSAGVITFFILTT-YLPFGC-----YGNKNIREAMNRPLRWPRPLK-------QVKKSDRTFVQSA
 ||              |||... ..    . |||| ||  . |.|    |          |. ..|   .  | |.|            .   .  .. 
LPI-----------RWMAPECINYGKFTT-KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQC

LVLKPSERPTARALLERL
   .|..||| ... |..
WHEDPEDRPTFSEIHECF
Kinase MARK4.AA Pkinase_Tyr 51-150 34 4e-12 41.67 Pfam 52-158 (270) Show / Hide 
Range on Protein: 51-150
Range on HMM: 52-158/270
Sequence Identity: 34% (38 aa)

RESEILFKL-NHENVVEIFDYFVF-QDHS---YIVLALAENGDMRNFVRQ----RGRLGEALALKMCEQIFEGVAYLHDTASVAHCDLKCENVLVDERED
|| .|. .| .|.|.|      .  |. .   |||. ....||.... |.    ...|     |.|| || .| .||..     | || . |.||.|   
REAKIMKQLGHHPNIVRLY-GVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN-CIHRDLAARNCLVTENNV

VKIADFGLA
|||.|||||
VKICDFGLA
Kinase MARK4.AA AMPK 202-241 47 5.9e-12 31.85 In-house 161-200 (254) Show / Hide 
Range on Protein: 202-241
Range on HMM: 161-200/254
Sequence Identity: 47% (19 aa)

GSPAYAAPEVLDSRVTDLRAADVWSAGVITFFILTTYLPF
||| |||||.  ..    .  |.|| ||| .  |  ||||
GSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF
Kinase MARK4.AA GIN4 202-241 55 2.6e-10 28.7 In-house 196-235 (293) Show / Hide 
Range on Protein: 202-241
Range on HMM: 196-235/293
Sequence Identity: 55% (22 aa)

GSPAYAAPEVLDSRVTDLRAADVWSAGVITFFILTTYLPF
||| |||||.   .  .  |.|||| ||| | .||  |||
GSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPF
Kinase MARK4.AA TSSK 202-241 47 4.2e-09 25.99 In-house 190-229 (289) Show / Hide 
Range on Protein: 202-241
Range on HMM: 190-229/289
Sequence Identity: 47% (19 aa)

GSPAYAAPEVLDSRVTDLRAADVWSAGVITFFILTTYLPF
|| ||||||.| ... |  ..|||| ||| .  ..  .||
GSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPF
Kinase MARK4.AA RAD53 202-242 32 5.7e-08 19.27 In-house 188-242 (305) Show / Hide 
Range on Protein: 202-242
Range on HMM: 188-242/305
Sequence Identity: 32% (18 aa)

GSPAYAAPEVLDSR--------------VTDLRAADVWSAGVITFFILTTYLPFG
|.|.| ||||. |               |   .. |.||.|.|.. .|. |.||.
GTPQYVAPEVITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFS
Kinase MARK4.AA Pkinase_Tyr 281-295 40 0.120197 6.2 Pfam 256-270 (270) Show / Hide 
Range on Protein: 281-295
Range on HMM: 256-270/270
Sequence Identity: 40% (6 aa)

KPSERPTARALLERL
.|..||| ....|.|
DPEDRPTFSEIHEQL