Gene DCAMKL1 (Sea Urchin)
DCAMKL1
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| DCAMKL1.AA | Protein | None | 636 | None | Fasta, JSON |
| DCAMKL1.kin_dom | Protein Kinase Domain | None | 258 | None | Fasta, JSON |
Protein domains of DCAMKL1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| DCX | DCAMKL1.AA | DCX | 107-193 | 35 | 4.4e-32 | 113.82 | SMART | 1-96 (96) | Show / Hide |
Range on Protein: 107-193 Range on HMM: 1-96/96 Sequence Identity: 35% (34 aa) ERRRPRQIIFFRNGDRFFKGKKMLITPHR-YTSFEDLLSELTR-----DMKLPYGVRQIFTPDG-TKVRDIEELKNG-ESYVCASFE-RLKKIKYK ...|. | |.||||.|||| . .|.. . ..||. || ..|. |..| ||| |.|.|| .|....|. .| ..|||.... ..|. .| HHWKPKRICFYRNGDPFFKGVRLVINRKWQFKSFDHLLQDVTQTKLHVKMDCPHGVRHIYTTDGRHRVTSLDEFEDGDDFYVCCCTNEKFKPVDYD |
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| DCX | DCAMKL1.AA | DCX | 129-188 | 38 | 6.8e-27 | 97.36 | Pfam | 1-68 (68) | Show / Hide |
Range on Protein: 129-188 Range on HMM: 1-68/68 Sequence Identity: 38% (26 aa) MLITPHRYTSFEDLLSELTR----DMKLPYG-VRQIFTPDG-TKVRDIEE-LKNGESYVCA-SFERLK |.. ..|. .|. || ..|. ..|| | || |.|||| ..| ...| |..|..|||. ..||.| MVVNRRRFKTFDALLDDITESLHDKVQLPFGAVRKIYTPDGGHRVTSLDEFLQDGGCYVCCCGNERFK |
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| Kinase | DCAMKL1.AA | DCAMKL | 340-597 | 62 | 7.1e-217 | 682.04 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 340-597 Range on HMM: 1-279/279 Sequence Identity: 62% (174 aa) YDIGAKIGDGNFADVHEATQKKTG-DEFALKV-----------------IEKAKVKNKEHMVENEIAIMKHVRHPNIVRLYEEYETRGHIYLVMEYVTGG |.||..|||||||.|||.....|| ...|.|. |.|.|.|.||||..||..||....||.|..|||...|. |.|||||||.|| YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG DLFDAITESVKFTERDAALMVTDLAKALKYLHDLNVVHRDLKPENLLVNKSESGEITLKLADFGLAMEVKE---PIYTVCGTPTYVAPEILGEKGYGLEV ||||||||..||||||||.|.|.|.|||||||..|.||||.|||||||.|.|.||..|||.|||||..|.. |.||||||||||||||| |.|||..| DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCKV DMWAIGVITYILLCGFPPFRSPDRDQEELFELIQEGAFSFVAPYWDNISSAAKDLINHLLVVNKEKRYTAGQVLKHPWV |.||.|||.||||||||||||||.||||||..|..|.|.|..|||||||..|||||.|.|.|..||||||.|...|||| DIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV |
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| Kinase | DCAMKL1.AA | CAMK1 | 340-597 | 46 | 2e-152 | 446.46 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 340-597 Range on HMM: 1-276/276 Sequence Identity: 46% (131 aa) YDIGAKIGDGNFADVHEATQKKT---GDEFALKVIE-KAKVKNKE----HMVENEIAIMKHV---RHPNIVRLYEEYETRGHIYLVMEYVTGGDLFDAIT | .| .|| | |..|...|.|.| |...|.|.|. | .|.|. ..||||.||| | ||||. .|| ||. |.|||||.||||.||| | YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV ESVKFTERDAALMVTDLAKALKYLHDLNVVHRDLKPENLLVNKSESGEITLK--LADFGLAMEVK-E--PIYTVCGTPTYVAPEILGE---KGYGLEVDM | ..||.||.. . ...|..|.|....||||||||||| .... . ..| .|||||. .. . .|.|||| |||||.| |.|. ..|| EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLY-YDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDM WAIGVITYILLCGFPPFRSPDRD-QEELFELIQEGAFSFVAPYWDNISSA-AKDLINHLLVVNKEKRYTAGQVLKHPWV | |||||||||||.||| | . ..||||.| .. . | |.|||||. |||.|.|.|.|. .||||. |.|.|||. WSIGVITYILLCGYPPFY--DENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | DCAMKL1.AA | CAMK | 345-597 | 27 | 2.1e-137 | 445.62 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 345-597
Range on HMM: 1-425/425
Sequence Identity: 27% (119 aa)
KIGDGNFADVHEATQKKTG------------DEFALKVIEKAKVKN---------------------------KEHMVENEIAIMKH-------VRHPNI
..| |.|. |.....|.|. ..| |.|.| |.|. ....|..||.|||. ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VRLYEEYE------------TRGH--------IYLVM---EYVTGG----DLFDAITES---------------VKFTERDAALMVTDLAKALKYLHDLN
..||| || | . .|.|| ||..|| |||| |.| .||||.|. .. .. |..|.|..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
VVHRDLKPENLLVNKSESGEI-------------TLKLADFGLAMEVKE--------------------------PIYTVCGTPTYVA-PEILG------
.|||||||||.|........ ..|..|||.| .... . .|.|||| |.| ||.|
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------EKGYGLEVDMWAIGVITYILLCGFPPFRSPDR-----------DQEELFELIQEGAFSFVAPY------------WDNISSA--------AK
...|| ..|||..|||.||.|||.|||..... ...|||| |..| ..| || ||.|| .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
DLINHLLVVNKEKRYTAGQVLKHPWV
|||...|.|. |||.|. |.|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | DCAMKL1.AA | CDPK | 340-597 | 41 | 1e-112 | 346.95 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 340-597 Range on HMM: 1-271/271 Sequence Identity: 41% (114 aa) YDIGAKIGDGNFADVHEATQK-KTGDEF-ALKVIEKAKVKNKE--HMVENEIAIMKHVRHPNIVRLYEEYETRGHIYLVME--YVTGGDLFDAITESVKF |.|. ..| |.| .| ...| ||..| | |.|.| .||.|| .. |||.|.| ||||...|| |. . ..|.||| |.|||.||| |.| .| YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF TERDAALMVTDLAKALKYLHDLNVVHRDLKPENLLVNKSESGEI---TLKLADFGLAMEVK-------EPIYTVCGTPTYVAPEILGEKGYGLEVDMWAI ||..||. .. . |. | |. |.|||||||||.| .. ... ..|. |.|.... . . ... ||||.|.|||.| | | ..| | . TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC GVITYILLCGFPPFRSPDRDQEELFELIQEGAFSFVAPYWDNISSAAKDLINHLLVVNKEKRYTAGQVLKHPWV ||| |||||| ||| . ..| .| ...| .|| | ||.||. |||||. .|... .||..| |.|.|||. GVILYILLCGYPPFYG--KNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | DCAMKL1.AA | S_TKc | 340-597 | 37 | 1.2e-112 | 381.4 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 340-597 Range on HMM: 1-231/231 Sequence Identity: 37% (102 aa) YDIGAKIGDGNFADVHEATQKKTGDEFALKVIEKAKVKNKEHMVENEIAIMKHVRHPNIVRLYEEYETRGHIYLVMEYVTG--GDLFDAITESVK----- |.|. ||| | |. |. .. |||| ..|.|.| ....||.|.|. .|||||.||. ... .|.|.||||. | ||||| | . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -FTERDAALMVTDLAKALKYLHDLNVVHRDLKPENLLVNKSESGEITLKLADFGLAMEVKEPIYTVCGTPTYVAPEILGEKGYGL-EVDMWAIGVITYIL |.| .|. .. ...||.|.|.....||||||||.|... ..|..||||| .. .|.|||| |.|||.| ||| ..|.|..|.| |.. PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM LCGFPPFRSPDRDQEELFELIQEGAFSFVAPYWDNISSAAKDLINHLLVVNKEKRYTAGQVLK-------HPWV ||| |||. .....|..| |. |||.|...|... |||.|| ..|. |||. LCGYPPFP----QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | DCAMKL1.AA | RAD53 | 340-597 | 38 | 2.7e-112 | 335.88 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 340-597 Range on HMM: 1-305/305 Sequence Identity: 38% (117 aa) YDIGAKIGDGNFADVHEATQKKTGDEFALKVIEK-------AKVKNKEHMVENEIAIMKHVRHPNIVRLYEEYETR-GHIYLVMEYVTGGDLFDAITESV |... ..| |||. | .| |||. .| | |.| .. .|. |.||. |.| . ||.|.|.|. ..| |.|.|..|||.||. | . YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK K----FTERDAALMVTDLAKALKYLHDLNVVHRDLKPENLLVNKSESGE--------------ITLKLADFGLAMEVKEP--IYTVCGTPTYVAPEILGE . |.| .. . . |.|||||.. .|||||||| | | . . . .|..||||. | | | ||||.|||||.. RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS K---------------GYGLEVDMWAIGVITYILLCGFPPFRSPDRDQ----EELFELIQE-GAFSFVAPYWDNISSAAKDLINHLLVVNKEKRYTAGQV | ||. .||.| .|.|.||.|||.||| | |..| ||| | | ..| |||| ||. |||||. .|.|. |||||. .. KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPF-SDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA LKHPWV | ||| LNHPWM |
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| Kinase | DCAMKL1.AA | Ciliate-E2a | 340-597 | 39 | 1.6e-107 | 317.55 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 340-597 Range on HMM: 1-275/275 Sequence Identity: 39% (111 aa) YDIGAKIGDGNFADVHEATQKKTGDEFALKVIEKAKVKNKE---HMVENEIAIMKHVRHPNIVRLYEEYETRGHIYLVMEYVTGGDLFDAITESVKFTER |.. ||| |||. | |..|.||..|| |...| | ... . ..|||.||. ..|||| .||| ||. ..||||||. ||.|.| | .. .|.| YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE --DAALMVTDLA-KALKYLHDLNVVHRDLKPENLLVN--KSES-GEITLKLADFGLAMEV--KEP--IYTVCGTPTYVAPEILGEKG------YGLEVDM ... . | ..| |.| .|..||||||||.| . ...| .|..||||| . .|. ... |||| |||||.| | |. .|| IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM WAIGVITYILLCGFPPFRSPDRDQEELFELIQEGAFSFVAPY-WDNISSAAKDLINHLLVVNKEKRYTAGQVLKHPWV | .||| |||||| ||| . .. .| .... . ..| | | ..|...|||. .|... .||.|| | |.|||. WSCGVIFYILLCGKPPF--KGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | DCAMKL1.AA | Pkinase | 340-597 | 37 | 2.2e-103 | 354.53 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 340-597 Range on HMM: 1-293/293 Sequence Identity: 37% (112 aa) YDIGAKIGDGNFADVHEATQKKTGDEFALKVIEKAKVKNKEHMVE---NEIAIMKHVRHPNIVRLYEEYETRGHIYLVMEYVTGG----DLFDAIT--ES | || ||| |.|. | ... |.||...|.|.|.| . | .... .||.|||...||||||||. .|...|||.||||. || |||| |. .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH VKF--TERDAALMVTDLAKALKYLHDLNVVHRDLKPENLLVNKSESGEI--TLKLADFGLA----MEVKEPIYTVCGTPTYVAPEILG-EKGYGLEVDMW .| .|... ... ....|.|.|. ...||||||||.|.. . |.| ..|..||||| .. .|.|||| |.|||.. ..|| .|||| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW AIGVITYILLCGFPPFRSP----DRDQEELFELIQEGAFSFVAPYWDNIS-----------------SAAKDLINHLLVVNKEKRYTAGQVLKHPWV ..|.| |..||| |||.. ..|| .....| .. ..| |.|..|| ...||.|. .| .. .||.|| |.|.|||. SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | DCAMKL1.AA | CAMKL | 340-597 | 35 | 1e-102 | 328.61 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 340-597 Range on HMM: 1-297/297 Sequence Identity: 35% (107 aa) YDIGAKIGDGNFADVHEATQ-KKTGDEFALKVIEKAKVKNKEHMVEN--------------EIAIMKHVR---HPNIVRLYEEYETRGH------IYLVM |.|| .| |.|. | || . || . | |.|.| | .|...| | ||.|||... ||||..||| .||. | ||||| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYVTGGD--LFDAITES----VKFTERDAALMVTDLAKALKYLHDLNVVHRDLKPENLLVNKSE-SGEITLKLADFGLA--ME-V----KEPIYTVCGTP ||. ||. ||| | . ...|..| . . . |..|.|....||||.||||.|. .. . ..|..|||.. .. . . | ||.| EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP TYVAPEILGE--K-GYGLEVDMWAIGVITYILLCGFPPFRSPDR------DQEELFELIQEGAFSFVAPYWDNISSAAKDLINHLLVVNKEKRYTAGQVL | ||||. | .| .||.|..||| | ..|| ||. .. .. .|.. | .| . . | | .| ..||| ..|.|| |||.|. |.. PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYP--PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM KHPWV .|||. NHPWM |
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| Kinase | DCAMKL1.AA | CAMK-Unique | 340-597 | 28 | 2.3e-100 | 332.03 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 340-597
Range on HMM: 1-363/363
Sequence Identity: 28% (102 aa)
YDIGAKIGDGNFADVHEATQKKTGDEFALKVIEKAKVKNKEHMV-------------------ENEIAIMKHVRHPNIVRLYEE----YETRG-------
|. . ||.||| | |.. ..||...| |...|....|| . ..|..|.| | ||||..||. ...|
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------HIYLVMEYVTGGDLFDAITE--------------------SVKFTE--RDAALMVTDLAKALKYLHDLNVVHRDLKPENLLVNKSESG----
..|.||||..||||||.| . .|.| .|... .. |. |..|.|....||||||.||..|..|.
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
--------EITLKLADFGLAMEVK----EP-IYTVCGTPTYVAP--------------EILGEKGYGLEV----DMWAIGVITYILLCGFPPFRSPDRDQ
.||.||||. .. .. . |.|||| |.|| |.... .|. . | |..|||.|..||| ||| ... |
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
------EELFELIQEGAF-SFVAPYWDN---ISSAAKDLINHLLVVNKEKRYTAGQVLKHPWV
|.|| | | . .| ..|. || .|||.. ...| .| .| . |.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | DCAMKL1.AA | RSK | 342-597 | 32 | 2.8e-97 | 329.49 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 342-597 Range on HMM: 1-278/278 Sequence Identity: 32% (91 aa) IGAK--IGDGNFADVHEATQKKTGDEFALKVIEKAKVKNKEH---MVENEIAIMKHVR-HPNIVRLYEEYETRGHIYLVMEYVTGGDLFDAITESVK--- . . .| | . ... |...|| ..| ||..|||..... . |. |..... ||.||.|.. ..| |..||.|||. ||.||. . . . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FTERDAALMVTDLAKALKYLHDLNVVHRDLKPENLLVNKSESGEITLKLADFGLAMEV----KEPIYTVCGTPTYVAPEILG----EKGYGLEVDMWAIG |.|..|. ...|...||.. ..|||||||| | . . .| ..|| |||.. . ... .| |.| |.|||.| ..|.. .| | | FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG VITYILLCGFPPFRSPDRD--QEELFELIQEGAFSFVAPYWDNISSAAKDLINHLLVVNKEKRYT-----AGQVLKHPWV |. | .| |.|||.. ..| ..|... ||.| ||. | |...| .|||||...| .. .||.. | ....||| VLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | DCAMKL1.AA | Ciliate-E2 | 340-597 | 27 | 4.6e-92 | 312.17 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 340-597
Range on HMM: 1-365/365
Sequence Identity: 27% (106 aa)
YDIGAKIGDGNFADVHEATQKKTGDEFALKVIEKAK--------------------VKNKEHMVENEIAIMKHVR----------------HPNIVRLYE
|.. ||| |||..| .....|.. .||.|.|. | ||. ....|| ||. .. ||||...||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE
EYE--TRGHIYLVMEYVTGGDLFDAITES-----------VKFTERDAALMVTDLAK---------------ALKYLHDLN-VVHRDLKPENLLVNKSES
.. .. .|||||||. |||||| | .. .|||. .. . . ... ||.||| | ..|||.||||.|.
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----
GEITLKLADFGLAMEVKEP----------------------------------IYTVCGTPTYVAPEILG---------EKGYGLEVDMWAIGVITYILL
.|..||||. ..... ..|.|||| |.|||||. .|||. ..|.|..||| |..|
----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML
CGFPPFRSPDRDQEELFELIQEGAFSFVAP--------------YWDNISSAAKDLINH----LLVVNKEKRYT-AGQVLKHPWV
.| ||| .. |... ..| | |...| .||||. .|... |||.| . |.|.|||
FGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | DCAMKL1.AA | Pkinase_Tyr | 340-497 | 33 | 7.7e-26 | 88.13 | Pfam | 1-170 (270) | Show / Hide |
Range on Protein: 340-497 Range on HMM: 1-170/270 Sequence Identity: 33% (58 aa) YDIGAKIGDGNFADVHEATQK----KTGDEFALKVI-EKAKVKN--KEHMVENEIAIMKHV-RHPNIVRLYEEYE-TRGH--IYLVMEYVTGGDLFDAIT .| |.| |.| .|...| | .|. . | |.. |.| .. .| . . |..|||. .|||||||| ... ||.||||. .||| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR E----SVKFTERDAALMVTDLAKALKYLHDLNVVHRDLKPENLLVNKSESGEITLKLADFGLAMEV-KEPIY-TV . ..| | | .. ||.. ||.. | .|||| | ||.. . . | .||||| . .. | .. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLARDIYNDDYYYRK |
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| Kinase | DCAMKL1.AA | TyrKc | 340-577 | 22 | 5.9e-16 | 35.28 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 340-577 Range on HMM: 1-280/280 Sequence Identity: 22% (66 aa) YDIGAKIGDGNFADVHEATQKKTGDEFALKVIEKAKVKNKEHMVENEIAIMKHV--RHPNIVRLYEEYETR-------GHIYLVMEYVTGGDLFDAITES | |.| |.| |...| | . | |.. . . . . .|. ||... .|||||||| . . ...||||. .||| | . .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH VK-FTERDAALMVTDLAKALKYLHDLNVVHRDLKPENLLVNKSESGEITLKLADFGLAMEVKEP-------IYTVC----GTPT-----YVAPEILGEKG . .. .| . .. |. |||. |..|||| | ||.. | | .||||. .... | . |. | ||| . .. RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YGLEVDMWAIGVITY-ILLCGFPPFRSP---DRDQEELFELIQEGAFSFVAPY--------------------WDNISSA---AKDLINHL . . | |. || . |. | .| . . . .|..|....| |. |. . .... . FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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