Gene TSSK4 (Sea Urchin)

TSSK4

Species: Sea Urchin
Alias: SPU_003424, TSSK4, Spk083
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CAMK
Family: TSSK

Sequence

Name Sequence Type Origin Length Description Download
TSSK4.AA Protein None 313 None Fasta, JSON
TSSK4.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of TSSK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TSSK4.AA TSSK 23-281 48 6.2e-187 618.57 In-house 1-289 (289) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-289/289
Sequence Identity: 48% (140 aa)

FNVQETVGHGSYAAVKCAYSTKHKCK----------------VAIKVVSKKKAPEDYLIKFLPREIQVVKI-LKHPNLICFLQSIETTS-RVYLIMELAD
.||....||||||.|.||||.|||||                ||||....||||.||| ||||||||.... |||||.|.|....||.. ..|..||.|.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

NGDLLDFIKAN------GAGTEEQTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHNMLKITDFGFARSKMKPPEPGRTILSETYCGSYAYAPPEIL
.||||..|...      || .|||...||.|.|....|||...||||||||||.||.||...|.|||||||. ..........||.|.|||||||.||||
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

RGIPYCPMLGDIWSMGVILYTMLYGRLPYDD--TNHKVLLNQVQ-RPPGFPT--SQVVHSDCKDLMCRILS-PAKRRINMEEIQHNAWY
|||||.|...|.||||||||.|..|..|.||  .|.. .|.|.| ... ||.  |. ....||||....|. ....|....||.|..|.
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase TSSK4.AA CAMK 28-281 22 2.2e-103 334.01 In-house 1-425 (425) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-425/425
Sequence Identity: 22% (97 aa)

TVGHGSYAAVKCAYSTKHK------------CKVAIKVVSKKKAPE-------------------------DYLIKFLPREIQVVKI-------LKHPNL
| |.||.. || .. .. .             |||||...|||...                         ..  |...|||.. |        |.|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ICFLQSIE------------TTSR--------VYLIM---ELADNG----DLLDFIKAN---------------GAGTEEQTGLWFHQLVDGMDYCHNLG
| ... .|            | |.        .|..|   |....|    ||.|.|...               |  ||...  .|.|......|||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKCENLLLNKH-----------------NMLKITDFGFARSKMKP------------------PEPGRTILSETYCGSYAYAP-PEILRG-----
.||||||.||.||...                 | .||.|||||. ...                   ..|. . . .|.||. .|.. ||.|.|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------IPYCPMLGDIWSMGVILYTMLYGRLPYDDT-------------NHKVLLNQVQRPP-GFPTSQV----------------------VHSDCK
        .||..   |.||.|||||.|| |..|...              | . |. ....    || ...                      |  .||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLMCRILSP-AKRRINMEEIQHNAWY
|| ...| .  ..|.. |..    |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase TSSK4.AA CAMKL 23-281 33 2.8e-98 314.27 In-house 1-297 (297) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-297/297
Sequence Identity: 33% (101 aa)

FNVQETVGHGSYAAVKCAYSTKH-KCKVAIKVVSKKKAPEDYLIKF------------LPREIQVVKILK---HPNLICFLQSIETTSR------VYLIM
... .| |.||.. || |  ... ..|||||.. |||. .|  .|             . ||||  | |.   ||| | ... ||| .       .||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELADNGD--LLDFIKANGA----GTEEQTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHN--MLKITDFGFARS-KM--KPPEPGRTILSETYCGS
|....|.  |.|.|...|      .|...   | |.|....|||..|.||||.| ||.|| ...   .||.||||.   .   ..|.     . .| |||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPG----QKLKTFCGS

YAYAPPEILRG--IPYCPMLGDIWSMGVILYTMLYGRLPYDDT--------NHKVLLNQVQRPPGFPTSQ-VVHSDCKDLMCRILSP-AKRRINMEEIQH
..|..|||. |   ||.    ||||.|||||.|..|.|| ||         |.  |.... .  ..|.    |  ||.||  ..| .  ..|.....|  
PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

NAWY
  |.
HPWM
Kinase TSSK4.AA S_TKc 23-281 26 7.1e-82 279.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-231/231
Sequence Identity: 26% (74 aa)

FNVQETVGHGSYAAVKCAYSTKHKCKVAIKVVSKKKAPEDYLIKFLPREIQVVKILKHPNLICFLQSIETTSRVYLIMELADN--GDLLDFIKANGA---
. . ...|.|... |.... .| . .||||...          . . ||||. |  .|||.. .. .... ...|..||..|.  |||.|.|| .|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---GTEEQTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHNMLKITDFGFARSKMKPPEPGRTILSETYCGSYAYAPPEILRGIPYCPMLGDIWSMG
    .| ..  ...|......|||..|..||||| ||.||..   .||.|||.||               |.||.  | .||.|   .| .   |.|| |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VILYTMLYGRLPYDDTNHKVLLNQVQRPPGFPTSQVVHSDCKDLMCRILS-PAKRRINMEEIQH-------NAWY
.||| ||.|. |..  .........             ...||.....|    ..|.   |. .         | 
CILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TSSK4.AA MARK 23-281 36 8.3e-80 260.57 In-house 1-262 (262) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-262/262
Sequence Identity: 36% (101 aa)

FNVQETVGHGSYAAVKCAYSTKHKCKVAIKVVSKKKAPEDYLIKFLPREIQVVKILKHPNLICFLQSIE--TTSR-VYLIMELADNGDLLDFIKAN--GA
. .  | |||||| || | ... . |||||.. |.|  .   .| . |||.. | |.||| |.... ||  |... .|||||.| .|.|.|.|||   | 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

GTEEQTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHN--MLKITDFGFARSK---MKPPEPGRTILSETYCGSYAYAPPEILRGIPYCPMLGDIWS
 .|| .   |.|.| .. |||. ..||||.|.||.|. ...    ||.||||..     .|          .| ||...|..|||. . ||.    ||||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK---------LNTFCGTPPYMAPEIFLKKPYDGPKVDIWS

MGVILYTMLYGRLPYDDTN--HKVLLNQVQRPPGF-PTSQVVHSDCKDLMCRILS-PAKRRINMEEIQHNAWY
.||.||.|. |..|.|...   | |  ...|.    |.   |  .|..| .|.|  . ..|. .|||    | 
LGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase TSSK4.AA AMPK 23-281 35 3.9e-78 231.57 In-house 1-254 (254) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-254/254
Sequence Identity: 35% (93 aa)

FNVQETVGHGSYAAVKCAYSTKHKCKVAIKVVSKKKAPEDYLIKFLPREIQVVKILKHPNLICFLQSI-ETTSRVYLIMELADNGDLLDFIKANGAGTEE
. ...| | |..  || .. .  . |||||.  |.|  ..   . . |||.  |...||..|   . | ||..  ...|| . .|.| |.|  .|  .|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

QTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHNMLKITDFGFARSKMKPPEPGRTILSETYCGSYAYAPPEILRGIPYCPMLGDIWSMGVILYTML
..   | | . | .|||....|||||| |||||.... .|| |||   |.|   . |   |. | |||  || ||.  | .||    |||| ||||| ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGL--SNMM--KDG-EFLK-TACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAML

YGRLPYDDTNHKVLLNQVQRPPGFPTSQVVHSDCKDLMCRILSPA-KRRINMEEIQHNAWY
 |.|| || |  .|   .     ... . . ...|||....| .    ||. ..|   .|.
CGYLPFDDENTPTLYKKIKNGE-YYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase TSSK4.AA Pkinase 23-281 26 1.5e-69 242.21 Pfam 1-293 (293) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-293/293
Sequence Identity: 26% (79 aa)

FNVQETVGHGSYAAVKCAYSTKHKCKVAIKVVSKKKAPEDYLIKFLP-REIQVVKILKHPNLICFLQSIETTSRVYLIMELADNG----DLLDFIK--AN
. . ...| ||.. |. ..  .  ..||.|...|... .. ..  .  .|||. | |.||| . .. . |. ...|..||....|    || |.|.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GAG--TEEQTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHNML----KITDFGFARSKMKPPEPGRTILSETYCGSYAYAPPEILRGIPYCPMLGD
|.   .|..   .. |.. |..|||. |..||||| ||.|..... .    ||.|||.|. .    .   .    |.||.. |..||..|| .| .   |
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVD

IWSMGVILYTMLYGRLPYDDT------NHKVLLNQVQR-PPGFPTSQV-------------------VHSDCKDLMCRILSP-AKRRINMEEIQHNAWY
.||.|.||| || ||.|...       ......... . |. |. ..                    ....|||.....| .  |.|.. |.| .  | 
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase TSSK4.AA ULK 23-280 26 8.1e-65 221.66 In-house 1-329 (329) Show / Hide 
Range on Protein: 23-280
Range on HMM: 1-329/329
Sequence Identity: 26% (87 aa)

FNVQETVGHGSYAAVKCAY-STKH---KCKVAIKVVSKKK--APE-----DYLIKFLPREIQVVKILK--------HPNLICFLQSIETT--SRVYLIME
... .  |.||.. |  ..   ..   . |||.|...|.|    .     .|....| .||.. | ||        ||| ....   ||.    .|.|||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LADNGDLLDFIKANGAGTEEQ----------TGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHN------------MLKITDFGFARSKMKPPEPGR
. . ||| ..|| |.  .|..          .   |.|.. |. . |  ...|||.| .| |.....             |||.|||||.. ... .  .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

TILSET----YCGSYAYAPPEILR----GIPYCPMLGDIWSMGVILYTMLYGRLP----YDDTNHKVLLNQVQ-----------RPPGFP---TSQVVHS
 ... .    .||.  |  |.||     ..||.    ||||.|.|.| ||||. |    . |.... . . ..           .|. ||    .... .
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

DCKDLMCRILSP-AKRRINMEEI-QHNAW
.||||  | |    | ||. ||. .|  .
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase TSSK4.AA ULK 23-280 27 1.1e-61 211.31 In-house 1-324 (324) Show / Hide 
Range on Protein: 23-280
Range on HMM: 1-324/324
Sequence Identity: 27% (91 aa)

FNVQETVGHGSYA-AVKCAY-STKH--KCKVAIKVVS------KKKAPE-DYLIKFLPREIQVVKILK---HPN--LICFLQSIETT--SRVYLIMELAD
... .  |.||..  |  ..   ..  . .||.|...      ||.  | .|....| .|||..|.||   |||   ....   ||.    .|.|||. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDLLDFIKANGAGTEEQ----------TGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHN------------MLKITDFGFARSKMKPPEPGRTIL
 ||| ..|| |.  .| .          .   |.|.. |. . |. ...|||.| .|.|.....             |||.|||||.. ... .     .
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNM--EQQM

SETYC------GSYAYAPPEILR----GIPYCPMLGDIWSMGVILYTMLYGRLP----YDDTN--HKVLLNQ-------VQ-RPPGFP---TSQVVHSDC
  |..      |.  |  |.||     ..||.    ||||.|.|.| ||||. |    . |..  .. |.|.       .. .|  ||    .... ..|
CQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPEC

KDLMCRILSP-AKRRINMEEI-QHNAW
|||  | |    | ||. ||| .|  .
KDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase TSSK4.AA QIK 23-281 31 2.3e-61 210.21 In-house 1-272 (272) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-272/272
Sequence Identity: 31% (91 aa)

FNVQETVGHGSYAAVKCAYSTKHKCKVAIKVVSKKKAPEDYLIKFLPREIQVVKILKHPNLICFLQSIETTSRVYLIMELADNGDLLDFIKANGA-----
. .  |.| | .| || |     | |||||.. | .  |..|.|   ||.|..| |.||. |  .| .|| .  |...| . ||.. | . ..|      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCY-REVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------GTEEQTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHNMLKITDFGFARSKMKPPEPGRTILSETYCGSYAYAPPEILRGIP
                .|...  || |.. . .|||....|||||| ||.|| .    || ||||        ..| .   .|.||| .|| ||.. |. 
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWF----KQGQLL--MTWCGSPPYAAPEMFEGKE

YCPMLGDIWSMGVILYTMLYGRLPYDDTNH-----KVLLNQVQRPPGFPTSQVVHSDCKDLMCRILS-PAKRRINMEEIQHNAWY
|  .  |||||||.|| .  | ||.|  .      .||  ... |.       . .|| .|  . |   ...|.... |    | 
YDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPF------FMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase TSSK4.AA SNRK 23-281 37 3.6e-59 192.3 In-house 1-254 (254) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-254/254
Sequence Identity: 37% (97 aa)

FNVQETVGHGSYAAVKCAYSTKHKCKVAIKVVSKKKAPEDYLIKFLPREIQVVKILKHPNLICFLQSIETTSRVYLIMELADNGDLLDFIKANGAGTEEQ
. ...|.|.| .| || |       |||.||. | |  ..     | .|.. .|. .|||..     |.|  ..|||.|| | .|. |.|     | .|.
YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKM-DEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCED

-TGLWFHQLVDGMDYCHNLGVVHRDLKCENLL-LNKHNMLKITDFGFARSKMKPPEPGRTILSETYCGSYAYAPPEILRGIPYCPMLGDIWSMGVILYTM
    .| |..  .|||| | ||||||| || .  .|  | |.|||||. . |    ||. .  ||.||| ||. |||| |  |     ||||.||||| .
LARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFM----PGEKL--ETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYML

LYGRLPYDDTNHKVLLNQVQRPPGFPTSQVVHSDCKDLMCRILS-PAKRRINMEEIQHNAWY
. |..|... |    | ..     .   ..|  .|.||. ..|    |.|  .|||. ..| 
VCGQAPFQEANDSETLTMIMD-CKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase TSSK4.AA GIN4 70-281 36 9.9e-56 176.29 In-house 83-293 (293) Show / Hide 
Range on Protein: 70-281
Range on HMM: 83-293/293
Sequence Identity: 36% (79 aa)

REIQVVKILKHPNLICFLQSIETTSRVYLIMELADNGDLLDFIKANGAGTEEQTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHNM-LKITDFGFA
||| ..|.. ||| .   .  || . .||..| |. |.| ...   |   |     .|.|.. |. ||| ....||||| ||||| . .  .|| ||| |
REIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMA

RSKMKPPEPGRTILSETYCGSYAYAPPEILRGIPYCPMLGDIWSMGVILYTMLYGRLPYDDT--NHKVLLNQVQRPP-GFPTSQVVHSDCKDLMCRILS-
  ...        | || |||  || |||  ||||     |.|| ||||. .| |.||.|.   | . || .||.     |  . . .. .||. .||  
ALETD------NKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVV

PAKRRINMEEIQHNAWY
  ..|| . .| .    
DPEKRIKTRDILKHPLI
Kinase TSSK4.AA Pkinase_Tyr 23-169 26 3.9e-23 78.99 Pfam 1-159 (270) Show / Hide 
Range on Protein: 23-169
Range on HMM: 1-159/270
Sequence Identity: 26% (43 aa)

FNVQETVGHGSYAAVKCAYST----KHKCKVAIKVVSKKKAPEDY--LIKFLPREIQVVKIL-KHPNLICFLQSIE-TTSR--VYLIMELADNGDLLDFI
    .. |.|..  |. .. .    ..|..||.|.. | .| ..   . .|.  |... | | .|||.....  .        .|..||.. .|||||. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KA----NGAGTEEQTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHNMLKITDFGFAR
..    ... | ..   . .|  .||.| .. . .|||| . | |... |  ||.||| ||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase TSSK4.AA TyrKc 23-280 19 5.2e-16 36.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 23-280
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

FNVQETVGHGSYAAVKCAYSTKHKCKVAIKVVSKKKAPEDYLIKFLPREIQVVKIL--KHPNLICFLQSIETT-------SRVYLIMELADNGDLLDFIK
    .. |.| .  |  .  .    .||.|.. . .     .  |. ||... . |  .|||.....  . .          ....||....|||.|...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ANGA-GTEEQTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHNMLKITDFGFARSKMKPPEPGRTILSETY------CGS----YAYAPPEILRGIP
...   . ..   . .|  .||.| |  ...|||| . | |... .  ||.||| .|      . |    ...|      .|     .   .|| .    
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPECI----

YCPMLG------DIWSMGVILYTML-YGRLPYDD-----TNHKVLLNQVQRPPGFPTSQV--------VHSDCKDLMCRILSP-AKRRINMEEIQHNAW
   . |      |.|| || .. .. ||  || .      . . ....|..    |  .          ...  ..| .     .. | ...|| |  .
---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase TSSK4.AA GIN4 23-59 37 8.8e-05 10.73 In-house 1-37 (293) Show / Hide 
Range on Protein: 23-59
Range on HMM: 1-37/293
Sequence Identity: 37% (14 aa)

FNVQETVGHGSYAAVKCAYSTKHKCKVAIKVVSKKKA
. . ||.| ||   |. |   .   . |.||.||||.
WKLGETLGFGSTGKVQLAKNMETGQRAAVKVISKKKI