Gene CDK9 (Sea Urchin)

CDK9

Species: Sea Urchin
Alias: CDK9, Spk129, SPU_012674
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK9

Sequence

Name Sequence Type Origin Length Description Download
CDK9.AA Protein None 410 None Fasta, JSON
CDK9.kin_dom Protein Kinase Domain None 297 None Fasta, JSON

Protein domain

Protein domains of CDK9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CDK9.AA CDK9 48-344 71 1.3e-258 865.44 In-house 1-340 (340) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-340/340
Sequence Identity: 71% (242 aa)

YDKLAKIGQGTFG-----------EVFKAKHKKNKNIVALKKVLMENEKEGFPITALREIRILQLLRHENVVPLYEICRTKATAYNRYKG--SIYLVFEF
|.|||||||||||           |||||.|||||..||.||||||||||||||||||||..||||.|||||.|.||||||||||||||.  ..||||.|
YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMENEKEGFPITALREIKMLQLLKHENVVNLIEICRTKATAYNRYKDRATFYLVFDF

CEHDLAGLLSNTNVKFSLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGVLKLADFGLARAFSLPKGDAPNR--YTNRVVTLWYRPPELLLGE
|||||||||||.|||||||.||.....|.|||||||.||.|||||||||.||||.|.|||||||||||||.||.|||||  ||||||||||||||||||.
CEHDLAGLLSNMNVKFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAFSQPKNDAPNRPLYTNRVVTLWYRPPELLLGD

RNYGPAIDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISHLCGSITSAVWPGLEKLELSNTL------ELPKGHKRKVKDRLRSYVK-------------
|||||.||.||||||||||||||||||||||||||.|||.||||||..|||..|..||.|..      |||||.|||||||...|.|             
RNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVWPNCENMELWNKMSSEPNSELPKGQKRKVKDRMKNYMKFDAPDSKTDPFGK

---------DQQALDLIDKLLNIDPKRRMDAAIALDHDFF
         ||||..|||||||||||.|||...|||||.|
NVKQHDSATDQQACHLIDKLLNIDPKKRMDSDEALDHDWF
Kinase CDK9.AA CDK 48-344 42 1e-163 527.81 In-house 1-284 (284) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-284/284
Sequence Identity: 42% (138 aa)

YDKLAKIGQGTFGEVFKAKHKKNK-----NIVALKKVLMEN-----EKEGFPITALREIRILQLLRHENVVPLYEICRTKATAYNRYKG----SIYLVFE
|.||.|||.||.|.|.||..|...     .||||||. |||     |||||||||.||| .|. | |.|.| |...| ||....|. |.    ..|.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

FCEHDLAGLLSNTNVKFSLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGV-----LKLADFGLARAFSLPKG-DAP--NRYTNRVVTLWYRP
...|||.....          ||. ..|||.||.|.|||...|||.| .||||.. |.     ||.|||||||||. |.  . .  . ||..|||||||.
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLWYRA

PELLLGERNYG--PAIDLWGAGCIMAEMWT---RSPIMQGNTEQHQLTLISHLCGSITSAVWPGLEKLELSNTLELPKGHKRKVKDRLRSYVKDQQALDL
||||||...|.  ..||.|..|||.|||.|   | |...|..|..|| .|. .||. |  .|||..|| .                            ||
PELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------DL

IDKLLNIDPKRRMDAAIALDHDFF
..|.|  |||.|. |  ||.|..|
LNKMLCYDPKKRISAEQALQHPYF
Kinase CDK9.AA CRK7 48-344 42 2.1e-140 472.74 In-house 1-343 (343) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-343/343
Sequence Identity: 42% (145 aa)

YDKLAKIGQGTFGEVFKAKHKKNKNIVALKKVLMENE---KEGFPITALREIRILQLLRHENVVPLYEICRTK--ATAYNRYKGSIYLVFEFCEHDLAGL
|.... || ||.| | ||| |... .|||||| |.||   |||||||| |||.||. | |.|.| | ||   |  | . ...|||.|.|||   |||.||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LSNTNVK-FSLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGVLKLADFGLARAFSLPKGDAPNRYTNRVVTLWYRPPELLLGERNY------
| .  .. ||....|.  |||| |. |.| ...|||| | .|||.   | .|.||||||| .   . .    |||||.||||||||||||| .|      
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYN--SEEKRRPYTNRVITLWYRPPELLLGEERYTEQHIL

--------------------------------GPAIDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISHLCGSITSAVWPGLEKLELSNTLELPKGHKRK
                                ||.|| |. |||..|  |. || ||| |  || .|. .||| . ..|| . || . ||.   . ..|.
KELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRR

VKDRLR----SYVKDQQALDLIDKLLNIDPKRRMDAAIALDHDFF
.         .   ....||| ||.|  ||| |. |  .|.||.|
LREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase CDK9.AA CMGC 48-344 24 2.6e-132 437.48 In-house 1-513 (513) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-513/513
Sequence Identity: 24% (128 aa)

YDKLAKIGQGTFGEVFKAKH--------------KKNKNIVALKKVL---MEN------EKEGFPITALREIRILQLLR-----------------HENV
|... |||.||.|.|.|...              .....|||.||.    .|.      ||.||||.|||||.||. |.                 |.|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VPLYEICRTKATAYNRYK---------GSIYLVFEFCEHDLAGLLSNTN--------VKFSLGE------------IKSVI------KQLLNGLY--YIH
| ||.|...| .. | |.          ..|||||...|||.... |..        ...|  .            ||. .      .|.|.||   |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SNK--VLHRDMKAANILITKA--------------------GVLKLADFGLARAFSLP------------------KGDAPNRYTNRVVTLWYRPPELLL
|..  ..|||.| .||||..                     |.||..||||||... .                  . .    ||..|||.|||.||.||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDD-KPNRPYTHYVVTRWYRAPEILL

GE---------RNYGPAIDLWGAGCIMAEMWTR--------SPIMQGNTE-----------QHQLTLISHLCGSIT---------------SAVWPGLEK
|          ..|...|| |..|||.|||.|.         |. .|..|           ..|| .|  ..|..|               .  ||.  |
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

LELSNT-------------------------LELPKGHKRKVKDRLRSYV---------------------------------KDQQALDLIDKLLNIDP
|   |.                         . .|. .... |.    .                                   |.||.||..|.| .||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

KRRMDAAIALDHDFF
..|. |. ||.|..|
DKRITAEQALQHPYF
Kinase CDK9.AA PITSLRE 48-344 40 2.2e-110 373.04 In-house 1-295 (295) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-295/295
Sequence Identity: 40% (123 aa)

YDKLAKIGQGTFGEVFKAKHKKNKNIVALKKVLME--NEKEGFPITALREIR-ILQLLRHENVVPLYEICRTKATAYNRYKGSIYLVFEFCEHDLAGLLS
. .| .|. ||.|.|..|| |.   |||||.. ||   ||||||||.||||  ||  |.|.|.| . ||   .       . .||.|.|. ||||..|. 
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSN------MDKIYMVMEYVEHDLKSLME

NTN---VKFSLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGVLKLADFGLARAFSLPKGDAPNRYTNRVVTLWYRPPELLLGERNYGPAIDL
| .    .|..||||. . |||.|  . |.|...||| | .|.|.. .|.||..|||||| .  |       ||  ||||||| |||||| . | ...|.
NMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSP----IKPYTPCVVTLWYRAPELLLGCKKYSTPVDM

WGAGCIMAEMWTRSPIMQGNTEQHQLTLISHLCGSITSAVWPGLEKLELSNTLE-LPKGHKRKVKDRLR--SYVKDQQALDLIDKLLNIDPKRRMDAAIA
|  |||.||. |  |..||. |  |.  |  . |  |   |||  .| ... .. .|.      . |     .. | ...||  ..|  .||.|. |  |
WSVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISD-TGFDLLNQMLTYNPKNRITASDA

LDHDFF
|.|..|
LKHPWF
Kinase CDK9.AA CDC2 48-344 37 7.50000000001e-110 338.88 In-house 1-301 (301) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-301/301
Sequence Identity: 37% (117 aa)

YDKLAKIGQGTFGEVFKAKHKKNKNIVALKKVLMENEKEG--FPITALREIRILQLLR-HENVVPLYEICRTKATAYNRYKGSIYLVFEFCEHDLAGLLS
| |. ||| ||.|.|.|.|... . ||||||.  |.| ||  .| ||.||| .|. |. |.|.| | ..             ..|.|||....||  .. 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---------NKLYMVFEYLDMDLKKYMD

---NTNVKFSLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGVLKLADFGLARAFSLPKGDAPNRYT--NRVVTLWYRPPELLLGERNYGPAI
    .| ....  .|| ..|.|.|. . |.....||| |  |||| |.|..|.|||||||||. |.    . ||    |||||||.||.|||.. |  ..
MSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPI----RTYTTEHEVVTLWYRAPEILLGCKRYSTPV

DLWGAGCIMAEM---WTRSPIMQGNTEQHQLTLISHLCGSITSAVWPGLEKLE-LSNTLELPKGHKRKVKDRLRS-------YVKDQQALDLIDKLLNID
|.|  |||.|||    |. |. .|  |  ||  |    |. ..  |||...|    ||   |. .. . .. . .          |....||....| .|
DMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNT--FPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYD

PKRRMDAAIALDHDFF
| .|  |  ||.| .|
PQKRISAKEALQHPYF
Kinase CDK9.AA CDK5 48-344 40 1.1e-103 328.59 In-house 1-287 (287) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-287/287
Sequence Identity: 40% (122 aa)

YDKLAKIGQGTFGEVFKAKHKKNKNIVALKKVLMENEKEGFPITALREIRILQLLRHENVVPLYEICRTKATAYNRYKGSIYLVFEFCEHDLAGLLSNTN
|.|. ||| ||.| |.||. |. . |||||.| ...| || | ||.||| .|. |.|.|.| |. .  .           . ||||||  ||   . . |
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKK--------LTLVFEFCDQDLKKYMDSCN

VKFSLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGVLKLADFGLARAFSLPKGDAPNRYTNRVVTLWYRPPELLLGERNYGPAIDLWGAGCI
.. ..  ||| . ||| || . |...|||||.|  | || | | ||||||||||||  |     . |.  |||||||||  |.| . |   ||.| .|||
GEMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPV----RCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCI

MAEMW-TRSPIMQGNTEQHQLTLISHLCGSITSAVWPGLEKLELSN--TLELPKGHKRKVKDRLRSYVK--DQQALDLIDKLLNIDPKRRMDAAIALDHD
.|||  .  |   || .. || .|  . |. .   ||.. ||   .    ..|. . ...   . . |.  |.. .||  |.| ..|. |..|. || | 
FAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQS---WQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHP

FF
.|
YF
Kinase CDK9.AA CDK7 48-344 35 1.4e-101 271.33 In-house 1-288 (288) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-288/288
Sequence Identity: 35% (109 aa)

YDKLAKIGQGTFGEVFKAKHKKNKNIVALKKVL----MENEKEGFPITALREIRILQLLRHENVVPLYEICRTKATAYNRYKGSIYLVFEFCEHDLAGLL
|.|...|| |.|. |.||  ..   ||| ||.      .  | |   ||.||| ||| ..|.||. |  |   |         .|.|||.| . ||    
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKS--------NIQLVFDFMDWDLEVVI

SNTNVKFSLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGVLKLADFGLARAFSLPKGDAPNR-YTNRVVTLWYRPPELLLGERNYGPAIDLW
    . .   .||.  ...| ||.| | | .||||.|  | |. . |.||.|||||||..      .||| ||  ||| ||| |||| | | ||...|.|
KDKSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYG-----SPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMW

GAGCIMAEMWTRSPIMQGNTEQHQLTLISHLCGSITSAVWPGLEKLELSNTLELPKGHKRKVKDRLRSYVK--DQQALDLIDKLLNIDPKRRMDAAIALD
  |||.||   | |.. |  .  ||| |    |  | . ||.. ..   ...   | .    .. || .     . .|||. ...  .| .|. .. .| 
SVGCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKF---KDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLK

HDFF
...|
MPYF
Kinase CDK9.AA Pkinase 48-344 32 4.5e-93 320.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-293/293
Sequence Identity: 32% (102 aa)

YDKLAKIGQGTFGEVFKAKHKKNKNIVALKKVLMENEKEGFPITALR--EIRILQLLRHENVVPLYEICRTKATAYNRYKGSIYLVFEFCEH-----DLA
| .. |||.|.||.|.|..||..  |||.|..  ..||.....|..|  ||.|.. |.|.|.| ||.....        |..||.|.|.||.     ||.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--------KDHIYMVMEYCEGGLYVMDLF

GLLS-NTNVKF--SLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGVL----KLADFGLARAFSLPKGDAPNRYTNRVVTLWYRPPELLLGER
 ..|   . .|  |  |.|....|.| ||.|.||....|||.| .|||| . |..    |..|||||. |.      .|..| ...|.||..||...| .
DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNSMTTFCGTPWYMAPEVIRGGQ

NYGPAIDLWGAGCIMAEMWTRSPIMQGN----TEQHQLTLISHLCGSITSAVWPGLEKLELSNTLELPKGHKRKVKDRLRSYVKDQQALDLIDKLLNIDP
 |||..| |..|||..|| .. |. .|     .   |. .|    | ...  || .    ... .   . |      ... .  .. ..|.|...|. ||
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---F-HWTF-HNWSEECKDFIKWCLCKDP

KRRMDAAIALDHDFF
|.|  |. .| |..|
KKRPTAEQILQHPWF
Kinase CDK9.AA S_TKc 48-344 27 3.1e-92 313.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-231/231
Sequence Identity: 27% (85 aa)

YDKLAKIGQGTFGEVFKAKHKKNKNIVALKKVLMENEKEGFPITALREIRILQLLRHENVVPLYEICRTKATAYNRYKGSIYLVFEFCEH---DLAGLLS
|..| |||.|.||.|.|..||| . |||.|..          ....|||.||.  .|.|.| ||.....         ...|.|.|.|..   ||  .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDYIK

NTNVK-----FSLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGVLKLADFGLARAFSLPKGDAPNRYTNRVVTLWYRPPELLLGERNYGP-A
. . .     |.  .......|....| |.||....||| | .|||...  ..|..|||||| .           |  ..|.||..||.|     ||. .
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL----GYGKCK

IDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISHLCGSITSAVWPGLEKLELSNTLELPKGHKRKVKDRLRSYVKDQQALDLIDKLLNIDPKRRMDAAIA
.| |  |||..|| .. |  .      |. .. ...|                                      ...|.|.|.|.|. ||..|. |  |
CDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EA

LD-------HDFF
|        | .|
LQDEWDIKCHPWF
Kinase CDK9.AA CDK10 48-344 40 2.6e-90 306.33 In-house 1-285 (285) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-285/285
Sequence Identity: 40% (119 aa)

YDKLAKIGQGTFGEVFKAKHKKNKNIVALKKVLMENEKEGFPITALREIRILQLLRHENVVPLYEICRTKATAYNRYKGSIYLVFEFCEHDLAGLLSNTN
..|| ..| ||.| |..|.  . . ||||||| |. ||.| || .|||| .|  .||||.| | |.   .         ||.|| ..|| ||| || |  
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLD------SIFLVMQYCEQDLASLLDNMP

VKFSLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGVLKLADFGLARAFSLPKGDAPNRYTNRVVTLWYRPPELLLGERNYGPAIDLWGAGCI
  |.  ..| .. |.| || |.|.| ..|||.| .|.|.|  | .|.|||||||....|    .   | ..|||||| |||||| |.   |||.| .|||
QPFTETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVP----VKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCI

MAEMWTRSPIMQGNTEQHQLTLISHLCGSITSAVWPGLEKLELSNTLELPKGHKRKVKDRLRSYVKDQQALDLIDKLLNIDPKRRMDAAIALDHDFF
..|.    |.| || | ||. .|  | |.   ..|||  .| . .   | |     .| .    .  |  . |.. |.  .||.|  |  .|.  .|
LGELLVHKPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFH--WLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase CDK9.AA MAPK 48-344 30 1.6e-80 273.84 In-house 1-328 (328) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-328/328
Sequence Identity: 30% (101 aa)

YDKLAKIGQGTFGEVFKAKHKK------NKNIVALKKVLMENEKEGFPITALREIRILQLL-RHENVVPLYEICRTK----ATAYNRYKGSIYLVFEFCE
|. | .|||| .| |..|..|.      ....||.||.    ... .   ..|||..|. . .|||.. |..| . .    .     ..  ||.|.|..|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFND-IYIVMELME

HDLAGLLSNTNVKFSLGEIKSVIKQLLNG--LYYIHSNKVLHRDMKAANILITKAGVLKLADFGLAR----AFSLPKGDAPN------RYTNRVVTLWYR
.||  ..   . . |   |.. . |.|.|  | ||||  |.||| | .|||... . ||..||||||      . ..... .        |  |.| |||
TDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYR

PPELLLG--ERNYGPAIDLWGAGCIMAEMWT-RSPIMQGNTEQHQLTLISHLCGSITSAVWPGLE-KLELSNTLE----LPKGHKRKVKDRLRSYV--KD
 ||..|.   ..|  |.| | .|||.||| | | |. .|.  ..|..||  ..|. .  ..  ..   .  | ..    |||  |.  .. .  ..  ..
APEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNAN

QQALDLIDKLLNIDPKRRMDAAIALDHDFF
 ||.||..|.| .||..| ... || | .|
PQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase CDK9.AA Pkinase_Tyr 48-202 30 2.6e-25 86.36 Pfam 1-160 (270) Show / Hide 
Range on Protein: 48-202
Range on HMM: 1-160/270
Sequence Identity: 30% (53 aa)

YDKLAKIGQGTFGEVFKAKHK----KNKNIVALKKV---LMENE--KEGFPITALREIRILQLL-RHENVVPLYEICRTKATAYNRYKGS--IYLVFEFC
  .. |.|.| ||||.|.. |    ..|  || |..    |. .  .| |    .||..|.  | .|.|.| || .|        . ...  ||.|.|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF----MREAKIMKQLGHHPNIVRLYGVCT-------DQGEPNQIYIVMEYM

EH-DLAGLLSNT---NVKFSLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGVLKLADFGLARA
.| ||   | .    . .... .. .   |  .|. | .|..  |||  | |.|.|. .| | .||||||.
PHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase CDK9.AA TyrKc 48-344 22 8.1e-13 -15.4 SMART 1-280 (280) Show / Hide 
Range on Protein: 48-344
Range on HMM: 1-280/280
Sequence Identity: 22% (70 aa)

YDKLAKIGQGTFGEVFKAKHKKNKNIVALKKVLMENEKEGFPITALREIRILQLL--RHENVVPLYEICRTKATAYNRYKGSIYLVFEFCEH-DLAGLLS
  .. |.| | ||||.|.. |     || |..  .          .||.||.  |  .|.|.| || .|...      | . ...|.|...| ||   | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYLR

NTNVKFSLGEIKSVIKQLLNGLYYIHSNKVLHRDMKAANILITKAGVLKLADFGLARAFSLP--KGDAPNRYT-----NRV--VTLWYRPPELLLGERNY
..  |... .  |   |  .|  |.||... |||  | |.|... .. | .||||.|.      .| .   |.     ..   . .   .|| .  .. .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKF

GPAIDLWGAGCIMAEMWTR----SPIM----QGNTEQHQLTLISHLCGSITSAVWPGLEKLELSNTLELPKGHKRKVKDRLRSYVKDQQAL-DLIDKLLN
 .. | |  |  | |. |.     | |      |.| ...    .      ..  | .                        . |   ... ... .  .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS-----------------------F-VCCPDEMYQIMKQCWH

IDPKRRMDAAIALDHDFF
 ||. |   .    |..|
EDPEDRPTFSEI--HECF