Gene CAMKK (Sea Urchin)

CAMKK

Species: Sea Urchin
Alias: CAMKK, Spk156, SPU_005878
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: CAMKK
Subfamily: CAMKK-Meta

Sequence

Name Sequence Type Origin Length Description Download
CAMKK.AA Protein None 794 None Fasta, JSON
CAMKK.kin_dom Protein Kinase Domain None 278 None Fasta, JSON

Protein domain

Protein domains of CAMKK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CAMKK.AA Meta 403-429 74 1.6e-21 58.84 In-house 1-27 (287) Show / Hide 
Range on Protein: 403-429
Range on HMM: 1-27/287
Sequence Identity: 74% (20 aa)

YHLKDEIGKGSYGVVKLAYSEEDDTNY
|.|..||||||||||||||.|||...|
YRLMEEIGKGSYGVVKLAYNEEDHHHY
Kinase CAMKK.AA CAMKK 403-429 53 2e-14 41.75 In-house 1-28 (396) Show / Hide 
Range on Protein: 403-429
Range on HMM: 1-28/396
Sequence Identity: 53% (15 aa)

YHLKDEIGKGSYGVVKLAYSEED-DTNY
|.|..|||.|..|.|||||.|.| ...|
YELMKEIGQGQFGKVKLAYNEYDTQKHY
Kinase CAMKK.AA MARK 403-422 50 7.6e-07 18.59 In-house 1-20 (262) Show / Hide 
Range on Protein: 403-422
Range on HMM: 1-20/262
Sequence Identity: 50% (10 aa)

YHLKDEIGKGSYGVVKLAYS
| .. .||.|||..|||| .
YKMLKTIGHGSYAKVKLACH
Kinase CAMKK.AA CAMKL 403-420 55 9.1e-07 17.47 In-house 1-18 (297) Show / Hide 
Range on Protein: 403-420
Range on HMM: 1-18/297
Sequence Identity: 55% (10 aa)

YHLKDEIGKGSYGVVKLA
| . ...||||.|.||||
YRIGKTLGKGSFGKVKLA
Kinase CAMKK.AA ULK 403-428 35 1.6e-05 15.62 In-house 1-28 (324) Show / Hide 
Range on Protein: 403-428
Range on HMM: 1-28/324
Sequence Identity: 35% (10 aa)

YHLKDEIGKGSYG-VVKLAYSEEDDT-N
| |....||||.| .|  .. ....| |
YCLNHCLGKGSFGVKVYKGRNKKTNTQN
Kinase CAMKK.AA CAMK 408-421 50 2.3e-05 12.45 In-house 1-14 (425) Show / Hide 
Range on Protein: 408-421
Range on HMM: 1-14/425
Sequence Identity: 50% (7 aa)

EIGKGSYGVVKLAY
..|.||.|.|||..
TLGRGSFGKVKLCI
Kinase CAMKK.AA ULK 403-417 53 3.4e-05 14.2 In-house 1-15 (329) Show / Hide 
Range on Protein: 403-417
Range on HMM: 1-15/329
Sequence Identity: 53% (8 aa)

YHLKDEIGKGSYGVV
|.|....||||.|.|
YCLNHCLGKGSFGKV
Kinase CAMKK.AA CAMKK-Unclassified 403-426 41 9.1e-05 11.12 In-house 1-24 (392) Show / Hide 
Range on Protein: 403-426
Range on HMM: 1-24/392
Sequence Identity: 41% (10 aa)

YHLKDEIGKGSYGVVKLAYSEEDD
| . |..| ||.| |||| .. ..
YEFLDKLGRGSFGKVKLATRRYTT
Kinase CAMKK.AA Ciliate-E2-Unclassified 403-425 26 0.000961 8.89 In-house 1-23 (352) Show / Hide 
Range on Protein: 403-425
Range on HMM: 1-23/352
Sequence Identity: 26% (6 aa)

YHLKDEIGKGSYGVVKLAYSEED
|..   ||.|..|.|.... ...
YKIIKQIGQGGFGKVYKCQHKKQ
Kinase CAMKK.AA Ciliate-E2 403-420 33 0.00106 8.56 In-house 1-18 (365) Show / Hide 
Range on Protein: 403-420
Range on HMM: 1-18/365
Sequence Identity: 33% (6 aa)

YHLKDEIGKGSYGVVKLA
| .   ||.|..|.|...
YKFIKKIGQGNFGSVYKC
Kinase CAMKK.AA Pkinase 403-421 42 0.001321 13.83 Pfam 1-19 (293) Show / Hide 
Range on Protein: 403-421
Range on HMM: 1-19/293
Sequence Identity: 42% (8 aa)

YHLKDEIGKGSYGVVKLAY
||..  ||.||.|.|....
YHIGRKIGSGSFGCVYKCH
Kinase CAMKK.AA Pkinase_Tyr 403-421 21 0.18955 5.53 Pfam 1-19 (270) Show / Hide 
Range on Protein: 403-421
Range on HMM: 1-19/270
Sequence Identity: 21% (4 aa)

YHLKDEIGKGSYGVVKLAY
 ..  ..|.|..|.|....
ITFGKKLGEGAFGEVYKGT
Kinase CAMKK.AA Meta 437-714 70 1.9e-265 775.81 In-house 1-287 (287) Show / Hide 
Range on Protein: 437-714
Range on HMM: 1-287/287
Sequence Identity: 70% (203 aa)

YHLKDEIGKGSYGVVKLAYSEEDDTNYAMKILSKKKLIKKGGFAKRPPPRGGKPNKA----PKTPLDRVYQEIAILKKLDHPNIVKLFEVLDDPNTDYLY
|.|..||||||||||||||.|||...|||||||||||.|..||..||||||.|||..    |..|||||||||||||||||||.|||.|||||||.||||
YRLMEEIGKGSYGVVKLAYNEEDHHHYAMKILSKKKLLKQYGFMRRPPPRGNKPNQGGCIQPRNPLDRVYQEIAILKKLDHPNVVKLVEVLDDPNEDYLY

MVFELVEKGPVMEVPSDNPLSEMLAWTYFRDIVQGIEFLHYQKVIHRDIKPSNLLLDDDNHVKIADFGVSDKFEGIDALLSD--TVGTPAFMAPESLLEE
||||.||||||||||.||||||..||.||||||.|.|.|||||.||||||||||||.||.||||||||||..|||.||.|..  |.|||||||||...||
MVFEYVEKGPVMEVPCDNPLSEDQAWSYFRDIVCGLEYLHYQKIIHRDIKPSNLLLNDDGHVKIADFGVSNEFEGDDAFLCNGSTAGTPAFMAPEACSEE

SNK-YGGRALDVWAMGCTLYCFLFGQVPFQD--NFILGLHNKIRTQPVMFPEDIEVSAEVKHLISRTLEKEPQKRITLPELKEDPWI
.|. |.||||||||||.|||||.|||.||.|  |.|..||.||...||||||..|.|...|..|.|.|.|.|..||..||.|..||.
QNHFYCGRALDVWAMGVTLYCFVFGQCPFIDKTNYIMCLHDKIKNHPVMFPEQPEISEDLKDCIKRMLDKNPEHRIMIPEIKTHPWV
Kinase CAMKK.AA CAMKK 437-714 39 1e-184 591.7 In-house 1-396 (396) Show / Hide 
Range on Protein: 437-714
Range on HMM: 1-396/396
Sequence Identity: 39% (157 aa)

YHLKDEIGKGSYGVVKLAYSEED-DTNYAMKILSK----KKLIKKGGFAKRPPPRGGKPNK----APKTPLDRVYQEIAILKKLDHPNIVKLFEVLDDPN
|.|..|||.|..|.|||||.|.| ...||.||..|    |||.|| .| ..||.|. ..|.    ....|.|.|||||||.||..|||||||.||.|||.
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

TDYLYMV-FELVEKGPVMEVPSDNP--------------------------LSEML---------------------AWTYFRDIVQGIEFLH-YQK---
 |..||| .|..|.|..|..|....                          .||.                      || ||||...|.|.|| |||   
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS

----------------VIHRDIKPSNLLLDDDN---HVKIADFGVSDKFEGIDALLSD-----------TVGTPAFMAPESLLEESNK------------
                .|||||||.|.|.|...   |||||||||| .|||.|..||.           |.|||||||||.. .| .|            
YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRF

-YGGRALDVWAMGCTLYCFLFGQVPFQDNFILGLHN---KIRTQPVMFPE-----------DIEVSAEVKHLISRTLEKEPQKRITLPELKEDPWI
 | |.|.|.||.|.|||||.||..||..|... ||.   ||  .|..|||           . |.|.. |.|| | |||.|.||||.|..|..||.
IYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase CAMKK.AA CAMKL 437-714 30 2.4e-98 314.45 In-house 1-297 (297) Show / Hide 
Range on Protein: 437-714
Range on HMM: 1-297/297
Sequence Identity: 30% (95 aa)

YHLKDEIGKGSYGVVKLAYS-EEDDTNYAMKILSKKKLIKKGGFAKRPPPRGGKPNKAPKTPLDRVYQEIAILKKLD---HPNIVKLFEVLDDPNT----
| . ...||||.|.||||       . .|.||. |||. ..    |....     .|  .. . |...||.|.|.|.   ||||.||.||...|..    
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCG-----QKH-ESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET

DYLYMVFELVEKGP------VMEVPSDN-PLSEMLAWTYFRDIVQGIEFLHYQKVIHRDIKPSNLLLDDDN--HVKIADFGVSDKFEGI----DALLSDT
...|.| |... |       . . .  . ...|  |  ||| || .....| ....|||||| |.|||...   .||.||| | ... .    . .|.  
KKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTF

VGTPAFMAPESLLEESNKYGGRALDVWAMGCTLYCFLFGQVPFQDN--------FILGLHNKIRTQPVMFPEDIEVSAEVKHLISRTLEKEPQKRITLPE
 |.|..|||| ..    .| |.. |.|..| .||  ..|..|| |          |  |..||...  ..|  ..|| ....||.. |.. | ||.|. .
CGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ

LKEDPWI
....|| 
IMNHPWM
Kinase CAMKK.AA S_TKc 437-714 30 9.9e-98 331.9 SMART 1-231 (231) Show / Hide 
Range on Protein: 437-714
Range on HMM: 1-231/231
Sequence Identity: 30% (89 aa)

YHLKDEIGKGSYGVVKLAYSEEDDTNYAMKILSKKKLIKKGGFAKRPPPRGGKPNKAPKTPLDRVYQEIAILKKLDHPNIVKLFEVLDDPNTDYLYMVFE
|.. ..||||..|.|....  ...  .|.||..                             .....||.|||| .|||||||..| .|   |.||||.|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVME

LVEK--GPVMEVPSDNP-------LSEMLAWTYFRDIVQGIEFLHYQKVIHRDIKPSNLLLDDDNHVKIADFGVSDKFEGIDALLSDTVGTPAFMAPESL
...   | ....  ...       ..|  |. |.. |....|..| ...||||.||.|.|||.  |.||.|||.. ..       .  .||| .|||| |
YCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL

LEESNKYGGRALDVWAMGCTLYCFLFGQVPFQDNFILGLHNKIRTQPVMFPEDIEVSAEVKHLISRTLEKEPQKRITLPELKE-------DPWI
     .||... |.|. ||.|| .| |. ||.   .  . .||.            | |.|..|.. |.|.|.||.|  |. .       .||.
-----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CAMKK.AA CAMK 442-714 22 6.7e-89 286.52 In-house 1-425 (425) Show / Hide 
Range on Protein: 442-714
Range on HMM: 1-425/425
Sequence Identity: 22% (100 aa)

EIGKGSYGVVKLAYSEEDD------------TNYAMKILSKKKLIKKGGFAKRPPPRGGKPNKA----------------PKTPLDRVYQEIAILKK---
..|.||.|.|||..  ..             . .|.||..|||| .|       .                             ...|..||.|.||   
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQN-QDY-S--------NCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQG

----LDHPNIVKLFEVLDDPN-----------------TDYLYMVF---ELVEKG----PVMEVPSDN----------------PLSEMLAWTYFRDIVQ
    ||||||.||.|| .||.                 ....|||.   |... |     . .   ..                 ..|  | .||| |..
IGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICS

GIEFLHYQKVIHRDIKPSNLLLDDD-----------------NHVKIADFGVSDKFEGI-----------------------DALLSDTVGTPAFMA-PE
.....| ....|||.|| |.||||.                 | .||.||| . ||..                        . .... .|||..|| ||
AVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE

SLLEES-----------NKYGGRALDVWAMGCTLYCFLFGQVPFQDNF-------------ILGLHNKIRTQPVMFPEDI--------------------
 |. ..           ..| |.. |.|..|. ||  | |  ||..               .  |. ||..    ||..                     
VLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEF

--EVSAEVKHLISRTLEKEPQKRITLPELKEDPWI
  .||.|.|.||.. |...|.||.|. . ...||.
HHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CAMKK.AA Pkinase 437-714 27 1.2e-83 288.94 Pfam 1-293 (293) Show / Hide 
Range on Protein: 437-714
Range on HMM: 1-293/293
Sequence Identity: 27% (89 aa)

YHLKDEIGKGSYGVVKLAYSEEDDTNYAMKILSKKKLIKKGG--FAKRPPPRGGKPNKAPKTPLDRVYQEIAILKKLDHPNIVKLFEVLDDPNTDYLYMV
||..  ||.||.|.|....   .   .|.||..|..  ..     ...                    .||.|.|.|.|||||.|...  |   |..|||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--------------------SEIQIMKRLNHPNIVRLYDWFED--KDHIYMV

FELVEKG----PVMEVPS---DNPL--SEMLAWTYFRDIVQGIEFLHYQKVIHRDIKPSNLLLDDDNHV----KIADFGVSDKF-EGIDALLSDTVGTPA
.|..|.|      ... |   ....  ||  .  |.. |..|.|..| ...||||.||.|.|.|...|.    ||.|||.. .| .  .  ... .||| 
MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW

FMAPESLLEESNKYGGRALDVWAMGCTLYCFLFGQVPFQDN------FILGLHNKIRTQPVMFPEDIEVS-------------------AEVKHLISRTL
.|||| ..  ...| |.. |.|..||.||..|.|. ||..         . ....|.  |..|... . |                    | |..|.. |
YMAPEVIR--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

EKEPQKRITLPELKEDPWI
.| |.||.| ......||.
CKDPKKRPTAEQILQHPWF
Kinase CAMKK.AA ULK 437-714 29 7.9e-69 234.97 In-house 1-324 (324) Show / Hide 
Range on Protein: 437-714
Range on HMM: 1-324/324
Sequence Identity: 29% (99 aa)

YHLKDEIGKGSYG-VVKLAYSEED---DTNYAMKILSKKKLIKKGGFAKRPPPRGGKPNKAPKTPLDRVYQEIAILKKLD---HPN--IVKLFEVLDDPN
| |....||||.| .|  .. ...   .  .| |. .|||..||   .       |      .  ..   .|| |.|||.   |||  ||||.... ..|
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQE------G------QYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSN

TDYLYMVFELVEKGPVMEVPSDNP----------LSEMLAWTYFRDIVQGIEFLHYQKVIHRDIKPSNLLLDDDN------------HVKIADFGVSDKF
 ...|...|. . |   .    |           |||. |  .|..|..|  .|| ...|||||||.|.|. ...            ..|||||| . |.
HNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA-KH

EGID----ALLSDTV------GTPAFMAPESLLEE--SNKYGGRALDVWAMGCTLYCFLFGQVP----FQDNF--ILGLHNK-------IRTQPVMFP--
   .     ..  .|      ||| .|||. | ..    .|.    |.| .|| .|  |.|..|    |.| .  |  | |.       |..||. ||  
VDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKP

-EDIEVSAEVKHLISRTLEKEPQKRITLPELKEDPWI
 .|. .| |.| ||.| |.... .||. .|. . ||.
PKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase CAMKK.AA ULK 437-714 28 1.5e-67 230.69 In-house 1-329 (329) Show / Hide 
Range on Protein: 437-714
Range on HMM: 1-329/329
Sequence Identity: 28% (97 aa)

YHLKDEIGKGSYGVVKLAYSEED----DTNYAMKILSKKKLIKKGGFAKRPPPRGGKPNKAPKTPLDRVYQEIAILKKLD--------HPNIVKLFEVLD
|.|....||||.|.|  .. ...    .  .| |...|.|...|   .       |      .  .. . .|| |.|||.        |||||||.... 
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQE------G------QYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFE

DPNTDYLYMVFELVEKGPVMEVPSDNP-----------LSEMLAWTYFRDIVQGIEFLHYQKVIHRDIKPSNLLLDDDN------------HVKIADFGV
..| ...|...|. . |  ..  . |            |||. |  .|..|..|  .|| ...|||||||.| |.....            ..|||||| 
TSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGF

SDKFEGID----ALLSDTV------GTPAFMAPESLLEE--SNKYGGRALDVWAMGCTLYCFLFGQVPFQDN-FILG------LHNK-------IRTQPV
. |.   |    ...  .|      ||| .|||. | ..    .|.    |.| .|| .|  |.|..||. . . .       | |.       |..|| 
A-KHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPL

MFP---EDIEVSAEVKHLISRTLEKEPQKRITLPELKEDPWI
 ||   .|. .| |.| ||.| |.... .||. .|| . ||.
QFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase CAMKK.AA Ciliate-E2-Unclassified 437-714 24 9e-67 228.14 In-house 1-352 (352) Show / Hide 
Range on Protein: 437-714
Range on HMM: 1-352/352
Sequence Identity: 24% (92 aa)

YHLKDEIGKGSYGVVKLAYSEEDDTNYAMKILSKKKLIK--------------------------KGGFAKRPPPRGGKPNKAPKTPLDRVYQEIAILKK
|..   ||.|..|.|.... ....  ||||...|.. .|                          |                      ..  |.  ||. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRK---------------------YNKIMQQ--ILLN

LDHPNIVKLFEVLDDPNTDYLYMVFELVEKGPVMEVPSD------------------NPLSEMLAW-----TYFRDIVQGIEFLHYQK-VIHRDIKPSNL
..||.|||.|..  |  ....|.| |..| |  ..  ..                  . ..|  |      .||. |.||.|.||... .|||||||.|.
HPHPFIVKMFYCFQD--KQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENI

LLDDDN---HVKIADFGVS---------DKFEG-------IDALLSDTVGTPAFM----APESLLEESNKYGGR---ALDVWAMGCTLYCFLFGQVPFQD
|.|...   ..||.||| |         | ...       .. ......||| .|    |||  . ....|...   . |.|..|. ||..|||. ||.|
LFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPE--VLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYD

-NFIL---------------GLHNKIRTQPVMFPE-DI-----EVSAEVKHLIS----RTLEKEPQKRITLPELKEDPWI
 | .                 |...|  ... ||. .       .| |.|..|.    . |.| | ||||...... ||.
NNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CAMKK.AA Ciliate-E2 437-714 21 1e-65 224.57 In-house 1-365 (365) Show / Hide 
Range on Protein: 437-714
Range on HMM: 1-365/365
Sequence Identity: 21% (86 aa)

YHLKDEIGKGSYGVVKLAYSEEDDTNYAMKILSKKKLIKKGGFAKRPPPRGGKPNKAP----------KTPLDRVYQEIAILK----------------K
| .   ||.|..|.|...   ... ..|.||   .|. . .   .          |.           |  .  . ||| |..                .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQM-Q---------EKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQ

LDHPNIVKLFEVLDDPNTDYLYMVFELVEKGPVME--------------VPSDNPLSEMLAWTYFRDIVQ---------------GIEFLHYQK-VIHRD
|.||||.|..|.  . .....|.|.|... |  ..                  ....|  . .... |.|               ..|.|| .. .||||
LNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRD

IKPSNLLLDDDNHVKIADFGVSDK------------------FEG--------------IDALLSDTVGTPAFMAPESLLEES------NKYGGRALDVW
|||.|.|.     .||.||| | |                  | .              .. .   ..||| .|||| |  ..       |. . . |.|
IKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW

AMGCTLYCFLFGQVPFQDNFILGLHNKIRTQPVMFP----------------EDIEVSAEVKHLISR----TLEKEPQKRIT-LPELKEDPWI
..|..||..|||. ||         ..|  ... ||                .  ..| |.|.||..     |.|.|.||||   .... ||.
SLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMKK.AA MARK 501-714 34 1.2e-54 177.1 In-house 46-262 (262) Show / Hide 
Range on Protein: 501-714
Range on HMM: 46-262/262
Sequence Identity: 34% (78 aa)

VYQEIAILKKLDHPNIVKLFEVLD--DPNTDYLYMVFELVEKGPVME-VPSD--NPLSEMLAWTYFRDIVQGIEFLHYQKVIHRDIKPSNLLLDDDN--H
|. ||.|.||||||||.|||.| .  ....  .|.. |....|.... . .    .|.| .| ..|| || .....| . ..|||||| |.|.|...   
VMREIEIMKKLDHPNIIKLFHVIEQDTEQH-QIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHN

VKIADFGVSDKFEGIDALLSDTVGTPAFMAPESLLEESNKYGGRALDVWAMGCTLYCFLFGQVPFQDNF--ILGLHNKIRTQPVMFPEDIEVSAEVKHLI
.||.||| | ...  . .|.   |||..|||| .| .  .| |.. |.|..|  ||  . |..|| .    .  |. ||..    .|    ||.| ..||
IKIIDFGFSICIP-PGQKLNTFCGTPPYMAPEIFLKK--PYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLI

SRTLEKEPQKRITLPELKEDPWI
.| |   | .|.|. |. ..||.
QRLLTVNPEERPTIEEIMKHPWM
Kinase CAMKK.AA CAMKK-Unclassified 552-714 27 3.7e-53 171.38 In-house 175-392 (392) Show / Hide 
Range on Protein: 552-714
Range on HMM: 175-392/392
Sequence Identity: 27% (60 aa)

LSEMLAWTYFRDIVQGIEFLHYQK---------------------VIHRDIKPSNLLLDDDNH-----VKIADFGVSDKFEGIDAL-LSDTVGTPAFMAP
..| ..  |||.. .|.  .| ..                     .||||||| |.|.|..       .||||||.| ..|. .   |... ||..||||
MHEQYLKKYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAP

ESLLEESNKYGGRA-------------------------LDVWAMGCTLYCFLFGQVPFQDNFILGLHN-KIRTQPVMFPE--DIEVSAEVKHLISRTLE
|..  | .||.. .                          |.|. | |.||. .. .||. .    | . .|    . ||     . |.| | || . ..
EFWSKENFKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCD

KEPQKRITLPELKEDPWI
| | ||||.  . ..||.
KNPKKRITIDQMLVHPWF
Kinase CAMKK.AA CAMKK-Unclassified 437-545 39 1e-27 87.09 In-house 1-111 (392) Show / Hide 
Range on Protein: 437-545
Range on HMM: 1-111/392
Sequence Identity: 39% (46 aa)

YHLKDEIGKGSYGVVKLAYSEEDD-----TNYAMKILSKKKLIKKGGFAKRPPPRGGKPNKAP-KTPLDRVYQEIAILKKLDHPNIVKLFEVLDDPNTDY
| . |..| ||.| |||| .. ..     . .| |.  | || ||  . .         .    |. |. |.||||| |||.||||.||.|| |||  | 
YEFLDKLGRGSFGKVKLATRRYTTDDGVQKQFAIKVFKKQKLKKKKFIYND------NAFTMKMKNRLHLVQQEIAIMKKLWHPNICKLYEVIDDPDNDK

LYM--VFELVEKGPVME
.||  | |....| .|.
IYMGQVMEYCQMGQIMS
Kinase CAMKK.AA TyrKc 437-712 20 9.7e-15 15.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 437-712
Range on HMM: 1-280/280
Sequence Identity: 20% (65 aa)

YHLKDEIGKGSYGVVKLAYSEEDDTNYAMKILSKKKLIKKGGFAKRPPPRGGKPNKAPKTPLDRVYQEIAILKKL--DHPNIVKLFEVLDDP-----NTD
 .|....| | .|.| ..      .. | | | . .                         .   ..|. |..||  .|||||.|. |  ..       .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIE

YLYMVFELVEKGPVMEVPSDNP----LSEMLAWTYFRDIVQGIEFLHYQKVIHRDIKPSNLLLDDDNHVKIADFGVSDKFEGI-------DAL------L
 |..|.|....|   .   ..     ....| . .  .| .| |.|| ...||||.   | |......|||.||| | . .         |         
PLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCW--QIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKG

SDTVGTPAFMAPESLLEESNKYG--GRALDVWAMGCTLY-CFLFGQVPFQD-----NFILGLHNKIRTQPVMFPEDI-------EVSAEVKHLISRTLEK
..|.     ||||..     .||    . |||. | ...  | .|| |  .          .......   | . .        . ..|.  ....  . 
GKTMLPIRWMAPECI-----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHE

EPQKRITLPELKEDP
.| .| |  |..|. 
DPEDRPTFSEIHECF
Kinase CAMKK.AA MARK 437-476 39 1.1e-09 28.0 In-house 1-41 (262) Show / Hide 
Range on Protein: 437-476
Range on HMM: 1-41/262
Sequence Identity: 39% (16 aa)

YHLKDEIGKGSYGVVKLAYSEEDDTNYAMKILSKKKLIK-K
| .. .||.|||..|||| .   ....| ||. |.|| . .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQ
Kinase CAMKK.AA Pkinase_Tyr 566-602 43 1e-05 20.02 Pfam 122-158 (270) Show / Hide 
Range on Protein: 566-602
Range on HMM: 122-158/270
Sequence Identity: 43% (16 aa)

QGIEFLHYQKVIHRDIKPSNLLLDDDNHVKIADFGVS
.| |.|. .. ||||.   | |....|.|||.||| .
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase CAMKK.AA Pkinase_Tyr 503-541 37 3.8e-05 18.04 Pfam 52-92 (270) Show / Hide 
Range on Protein: 503-541
Range on HMM: 52-92/270
Sequence Identity: 37% (16 aa)

QEIAILKKL-DHPNIVKL---FEVLDDPNTDYLYMVFELVEKG
.|..|.|.| .|||||.|       ..||  ..|.|.|....|
REAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHG
Kinase CAMKK.AA Pkinase_Tyr 437-455 21 0.18955 5.53 Pfam 1-19 (270) Show / Hide 
Range on Protein: 437-455
Range on HMM: 1-19/270
Sequence Identity: 21% (4 aa)

YHLKDEIGKGSYGVVKLAY
 ..  ..|.|..|.|....
ITFGKKLGEGAFGEVYKGT