Gene MOS1 (Sea Urchin)

MOS1

Species: Sea Urchin
Alias: Spk165, SpMOSa, MOS1, SPU_012529
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: MOS

Sequence

Name Sequence Type Origin Length Description Download
MOS1.AA Protein None 418 None Fasta, JSON
MOS1.kin_dom Protein Kinase Domain None 267 None Fasta, JSON

Protein domain

Protein domains of MOS1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MOS1.AA MOS 144-410 52 7.89999999999e-197 658.41 In-house 1-299 (299) Show / Hide 
Range on Protein: 144-410
Range on HMM: 1-299/299
Sequence Identity: 52% (158 aa)

FQVEGLIGSGGFGSVFVGKYCGRRVAVKVLRPRRKNAEAMLQSFRAEVNALYLKHENIVNVLATS--AVEDFEAGAFIIMEYAGKRNLQQLINEPSERLP
......||.||||||....||||.||||......||..||..||.||||.|.|.|.|||.|.|.|  ..|||.....||||..|...|.|.|.||....|
VCLCQMIGRGGFGSVWKAQYCGRPVAVKQVNKCTKNLKAMRRSFWAEVNYLRLRHDNIVRVMAVSQRSPEDFNNLGTIIMECGGNQTLHQVIYEPTRHPP

------------LARRANFALHIIRALQYTHAHNIAHLDVKPANIIVDD-----------------YDVCRLCDYGCSQQVFGSNGKGLRSPTNRSYLTG
            |.......|....||||.|..||.||||||||||||.                 .|||.|||.|||||.|.||||.....||..||.|
GDAGIIHCRMLILMHCCKYSLDVVNALQYCHHQNILHLDVKPANIIVDEGTKSSITCNSSKIKVKRQDVCKLCDFGCSQQMFDSNGKEFCAWTNPHYLKG

TCGYRAPELLCGDAPTTKADIYSFGITLWQMLTRETPYAG-ENHHVVIFGVVAKDMRPKLPGNENETENDWYRRLITKAWPKQPEDRPTARELLKELEM
||.|.||||||||.||.||||||||||.|||.||||||.| ..|||....|....|||..|..||..||||||.||.|.||||||.||.||.|..||||
TCTYMAPELLCGDTPTPKADIYSFGITMWQMQTRETPYHGEDCHHVYAYQVYKHRMRPDNPVYENSCENDWYRQLIQKCWPKQPEQRPSARQLKHELEM
Kinase MOS1.AA TKL 150-408 24 4.4e-60 205.93 In-house 1-364 (364) Show / Hide 
Range on Protein: 150-408
Range on HMM: 1-364/364
Sequence Identity: 24% (91 aa)

IGSGGFGSVFVGKYCG----------RRVAVKVLRPRR----------------------KNAEAMLQSFRAEVNALY---LKHENIVNVLATSAVEDF-
||||||| |. ||. |          . ||||... .                       .. ||.   |. |. ..    |.|.|||  .. .  ... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------EAGAFIIMEYAGKRN-LQQLINEPSERLPLARRANFALHIIRALQYTHAHN--------IAHLDVKPANIIVD-DYDV-------------
         .   .|.|||. . . | .|.        . .| ..|| | |...| |..|        |.| | |..|| || .. .             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

CRLCDYGCSQQVFGSNGKGLRSPT------------NRSYLTGTCGYRAPELLCGD----------------APTTKADIYSFGITLWQMLTRETPYAGE
| .||.| |. ...|...   . |            ...   || .. |||.| |.                  ..|.|.||||| || .|||..||...
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

NHHVVI---------FGVVAKDMRPKLPGNENE-----TENDW---YRRLITKAWPKQPEDRPTARELLKEL
..  .|          .|. | .|| .|   ..      ..|    ...|... |   ||.||.. |.||.|
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MOS1.AA Pkinase 144-408 23 1e-48 172.99 Pfam 1-293 (293) Show / Hide 
Range on Protein: 144-408
Range on HMM: 1-293/293
Sequence Identity: 23% (71 aa)

FQVEGLIGSGGFGSVFVGKYCGRR--VAVKVLRPRRKNAEAMLQSFRA--EVNAL-YLKHENIVNVLATSAVEDFEAGAFIIMEYAGKR----NLQQLIN
..... ||||.||.|. ..  | .  ||||... | .. . ..|. |   |.  .  |.|.|||  . .   .|      ..|||...      |  .| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY---MVMEYCEGGLYVMDLFDYIS

-EPSERL--PLARRANFALHIIRALQYTHAHNIAHLDVKPANIIVDDYDVC----RLCDYGCSQQVFGSNGKGLRSPTNRSYLTGTCGYRAPELLC-GDA
 . . ..  .     .... |.|.|.| |...| | |.||.|| .|. ...    ..|| |.. |.       . . .  . ..|| .|.|||..  |  
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQY

PTTKADIYSFGITLWQMLTRETPYAGE---NHHVVIFGVVAKDMRPKLPGNENETEN-------------------DWYRRLITKAWPKQPEDRPTAREL
 ..|.|..|.|..|..||....|. |.    . .    .....|.|.|. .. .. .                   .. . .|.. . | |..||||...
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

LKE--L
|.   .
LQHPWF
Kinase MOS1.AA S_TKc 144-406 24 1.7e-48 168.38 SMART 1-220 (231) Show / Hide 
Range on Protein: 144-406
Range on HMM: 1-220/231
Sequence Identity: 24% (68 aa)

FQVEGLIGSGGFGSVFVGKYCG--RRVAVKVLRPRRKNAEAMLQSFRAEVNALYLKHENIVNVLATSAVEDFEAGAFIIMEYAGK--RNLQQLINEPSER
...  .||.|.||.|. ..  .  |.||.|...          ...| |.. |  .|.|||. . .          ...|||..    .| ..| .   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKKHHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LPLARRANFALHIIRALQYTHAHNIAHLDVKPANIIVDDYDVCRLCDYGCSQQVFGSNGKGLRSPTNRSYLTGTCGYRAPELLCGDAPTT-KADI
     .|  . . ..  |..||.| | |.| | |.||.|| .|.  .  .|| | . |.              . . ||  |.|||.|     .. |.|.
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDW

YSFGITLWQMLTRETPYAGENHHVVIFGVVAKDMRPKLPGNENETENDWYRRLITKAWPKQPEDRPTARELLK
.|.|..|. ||....|.    .. ..| ..                 .  . .| | . | ||.|||| |.|.
WSCGCILYEMLCGYPPFP---QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQ
Kinase MOS1.AA MLK 144-408 24 1.2e-40 138.71 In-house 1-291 (291) Show / Hide 
Range on Protein: 144-408
Range on HMM: 1-291/291
Sequence Identity: 24% (75 aa)

FQVEGLIGSGGFGSVFVGKYCGRR-----VAVKVLRPRRKNAEAM----LQSFRAEVNAL-YLKHEN----IVNVLATSAVEDFEAGAFIIMEYAGKRNL
.|..  ||||.||.|. |.. ...     ||||  | |   . .      . |. |.. |  |.|.|    |. ...... .    . .|.|||. .  |
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP--CHFCIVMEYCEGGSL

QQLINEPSE-------------RLPLARRANFALHIIRALQYTHAHN---IAHLDVKPANIIVDD------YDVCRLCDYGCSQQVFGSNGKGLRSP-TN
  .... .              . ...  .|.|| . |...| |..    | | | |. || .|.      ..... || | |          . .  ||
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRD--------WHQMCTN

RSYLTGTCGYRAPELL---CGDAPTTKADIYSFGITLWQMLTRETPYA-GENHHVVIFGVVAKDMRPKLPGNENETENDWYRRLITKAWPKQPEDRPTAR
.    ||. ..||| .    ..  . |.|..|.|. ||.|||||.||. . .   ....|...  || .| .     ..   .|... |   |..||. |
MMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST----CPEHWKKLMKQCWNQDPHKRPSFR

ELLKEL
. ...|
QIVQHL
Kinase MOS1.AA STE 144-411 20 2.2e-40 140.31 In-house 1-359 (359) Show / Hide 
Range on Protein: 144-411
Range on HMM: 1-359/359
Sequence Identity: 20% (77 aa)

FQVEGLIGSGGFGSVFVGKYC-----------------GRRVAVKVLRPRRKNA--------------EAMLQSFRAEVNALYLK---HENIVNVLATSA
..  . ||.|.||.|. ...                  |...|.|... ...|.              .  .|..  |.. .      |.|||. . .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VED--FEA--GAFIIMEYAGKRNLQQLIN---EPSERLP----------LARRANFALHIIRA-LQYTHAHNIAHLDVKPANIIVDDYDVCRLCDYGCSQ
.|.   ..    .|.||| .   | ..|.   .. ..|.              | ..  |... |.| | |.| | |.||||| .     . ||| |.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QVFGSNGKGLRSP-----------TNRSYLTGTCGYRAPELLCGDAPT------TKADIYSFGITLWQMLTRETPYAGENHHVVIFGVVAK---------
|.  |. .. .              .|  ..||  . ||| . ..  .      ||.||.|.|.|.. |.| . |.. .... ..|    .         
QLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----DMRPKLPGNENETEN---------------DWYRRLITKAWPKQPEDRPTARELLK-ELEMR
     .  |.|| .  . |                .  .  | |   | |..|||| .||| | .  
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MOS1.AA TK 144-408 14 5.5e-37 120.98 In-house 1-486 (486) Show / Hide 
Range on Protein: 144-408
Range on HMM: 1-486/486
Sequence Identity: 14% (70 aa)

FQVEGLIGSGGFG---SVFVGKYCGR---------------------------RVAVKVLRPRRKNAEAMLQS--------------FRAEVNALY---L
 ...  .|.| ||    |. |.. ||                           .||||.|..   ..... .               . .|   .    .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KHENIVNVLATSAVEDF---------EAGAFIIMEYAGKRN----LQQLINEPSER--------------------------------------------
.|.|||. .. .  ..          .    |.|||. . .    |..   . ...                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LPLARRANFALHIIRALQYTHAH------NIAHLDVKPANIIVDDYDV-----------CRLCDYG---
                               |.....  ... | ....| |..      |. | |.   |. |.. .|           |...|.|   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----CSQQVFG------SNGKGLRSPTNR---------SYLTGTCG-----YRAPELLCGDA---------PTTKADIYSFGITLWQMLTRE-TPYAGE
      .  .        ....| . |  .          |.  . |     . ||| | .            ||| |..|||...| ..|.  .||.|.
QGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

NHH---------VVIFGVVAKD--------------MRPKLPGNEN----------ETENDWYRRLITKAWPKQPEDRPTARELLKEL
 ..           ..  . .               ||.. | .            ... . | .|... | ..|||||| ..|...|
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase MOS1.AA TKL-Unique 146-408 27 9.8e-36 123.55 In-house 1-290 (290) Show / Hide 
Range on Protein: 146-408
Range on HMM: 1-290/290
Sequence Identity: 27% (80 aa)

VEGLIGSGGFGSVFVGKYCGRRVAVKVLRPRRKNAEAMLQSFRAEVNAL-YLK-HENIVNVLATSAVEDFEAG-AFIIMEYAGKRNLQQLIN--------
.  .||.||.|.|. ||. |  ||.|.. |  .    |.| |. ||| .  |. |.|||   .... .   ..  .|.|||    .|  ...        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-EPSERLPLARRANFALHIIRALQYTHAHN--IAHLDVKPANIIVDDY-----DVCRLCDYGCSQQVFGSNGKGLRSP--TNRSYLTGTCGYRAPELLCG
 ...  |....| ..|. | ... | |  .  |.|.| |. |. ||          ..|| | |     .| . .. .  |. .   |.  ..|||.|..
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--DAPTTKADIYSFGITLWQMLTRET------PYAGENHHVVI--FGVVAKDMRPKLPGNENETENDWYRRLITKAWPKQPEDRPTARELLKEL
  .  ..|.|.||||| || ..||.       || | ..  ..    .. .  ||..| . ..     || ||.. |  .|..||.  | ...|
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKE----YRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase MOS1.AA Ciliate-E2 144-406 18 9.5e-32 106.25 In-house 1-361 (365) Show / Hide 
Range on Protein: 144-406
Range on HMM: 1-361/365
Sequence Identity: 18% (70 aa)

FQVEGLIGSGGFGSVFVG--KYCGRRVAVKVLRPRR--------------KNAEAM----LQSFRAEVNAL-----------------YLKHENIVNVLA
. .  .||.|.||||. .  .  ....| |. . .               .. . |    ....  | . .                  |.| ||..   
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY-

TSAVED-FEAGAFIIMEYAGKRNLQQLIN-----EPSE-----RLPLARRANFALHIIR---------------ALQYTHAHN-IAHLDVKPANIIVDDY
  . ..  .   ...|||.   .|...|.     ...|     .. .  ....  .|..               ||.| |  | | | | || ||..   
-ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

DVCRLCDYGCSQQVFGSNGKGL---------------RSPTNRSYL----------TGTCGYRAPELLCGDA---------PTTKADIYSFGITLWQMLT
  . ..| | |...  .| ...               |.|.. . .           || || ||| | |            ..|.||.|.|..| .||.
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD-QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

RETPYAGENHHVVIFGVVAKDMRPKLPGNENETENDWYR-----------------RLITK----AWPKQPEDRPT-ARELLK
 ..|.              . .  |.  ...| ..| .                   || |       |.|| |.| . ..|.
GKPPF------------QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase MOS1.AA Dicty4-Unclassified 144-408 28 6.4e-30 99.64 In-house 1-263 (263) Show / Hide 
Range on Protein: 144-408
Range on HMM: 1-263/263
Sequence Identity: 28% (77 aa)

FQVEGLIGSGGFGSVFVGKYCGRRVAVKVLRPRRKNAE-AMLQSFRAEVNAL-YLKHENIVNVLATSAVE-DFEAGAFIIMEYAGKRNLQQLIN-EPSER
 |.   || | |  |  |   |. |||| .   .  .   |.| |..||  |  . | | | .   .       .   |.||   | ||  .|.  |||.
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

---LPLAR--RANFALHIIRALQYTHAHNIAHLDVKPANIIVDDYDVCRLCDYGCSQQVFGSNGKGLRSPTNRSYLTGTCGYRAPELLCGDAPTTKADIY
   . |       .|. | . .|. |  |. | |.| .|| .|     .  | | |  .  ..        |     ||    .|| | . . . |.|.|
QQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVI--DFNF------NMTTIAGTPKWESPECLMHESYNQKSDVY

SFGITLWQMLTRETPYAGENHHVVIFGVVA-KDMRPKLPGNENETENDWYRRLITKAWPKQPEDRPTARELLKEL
|... |. ..| . || .    . .   |. | .|||.| |    .| | ..||   |   |  |||  .  . |
SYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDN---CDNFW-KKLIKWCWHNDPNKRPTMNQIIQYL
Kinase MOS1.AA Dicty4 219-410 29 1.5e-28 92.51 In-house 79-277 (277) Show / Hide 
Range on Protein: 219-410
Range on HMM: 79-277/277
Sequence Identity: 29% (61 aa)

IIMEYAGKRNLQQLINE------PSERLP--LARR-ANFALHIIRALQYTHAHN--IAHLDVKPANIIVDDYDVCRLCDYGCSQ--QVFGSNGKGLRSPT
| .||  | ||  |..       .|  |.  | .|    |. . | ... |. |  | |.| |..|. ||.  .   || | ||  .   ... .. .. 
IVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTA-

NRSYLTGTCGYRAPELLCGDAPTTKADIYSFGITLWQMLTRETPYA--GENHHVVIFGVVAKDMRPKLPGNENETENDWYRRLITKAWPKQPEDRPTARE
      || .. ||| . ... . ||| ||||| ||..|||. ||.  . .   ....|. | .||..| .        ...||.. | . |. ||.  |
-----CGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPS----WKHLIQWCWDHDPQHRPSFEE

LLKE--LEM
 ...  || 
IIQRRILEH
Kinase MOS1.AA LRRK 219-410 24 3.1e-23 79.04 In-house 132-351 (351) Show / Hide 
Range on Protein: 219-410
Range on HMM: 132-351/351
Sequence Identity: 24% (56 aa)

IIMEYAGKRNLQQLINEPSE--------RLPLARRANFALHIIRALQYTHAHN--IAHLDVKPANIIVDDYD------------VCRLCDYGCSQ--QVF
..||||   .|.... ....        ...   .   ||.| ....| | ||  | | | |. ||..   .            .. ..|.| |.  |.|
MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCF

GSN-GKGLRSPTNRSYLTGTCGYRAPELLCGD---APTTKADIYSFGITLWQMLTRETPYAGENH-------HVVIFGVVAKDMRPKLPGN-ENE----T
..   ||         ..|. |..||| . ..     |.|.|.||||. ||  |||. .. .|         .  |   . .  ||..| . ...    .
HMGVAKG---------CVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWH

ENDWYRRLITKAWPKQPEDRPTARELLKELEM
.   |  ||.. |  .|..||.. . .| |. 
M---YQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase MOS1.AA TyrKc 144-408 22 5.3e-17 52.14 SMART 1-280 (280) Show / Hide 
Range on Protein: 144-408
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

FQVEGLIGSGGFGSVFVGKYCGRRVAVKVLRPRRKNAEAMLQSFRAEVNAL-YL--KHENIVNVLATSAVEDFE-----AGAFIIMEYAGKRNLQQLINE
 . .  .|.| || |. |..  . ||||.|..        .. |. | . .  |  .|.|||. ..  ......        .|.|||. . .|.. . .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYG-VCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

PSERLPLARRANFALHIIRALQYTHAHNIAHLDVKPANIIVDDYDVCRLCDYGCSQQVFGS--NGKGLRSPTNRSYLT------GT--CGYR--APELLC
. ..|...   .|.. | .  .| | .|. | |    |. |..  ... .| | |  .     .|       . .| .      |     .|  ||| . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG------ESKDYYRKKEHKGGKTMLPIRWMAPECIN

GDAPTTKADIYSFGITLWQMLTR-ETPYAGE----NHHVVIFGVVAKDMRPKLPGN-ENE-----TENDWYRRLITKAWPKQPEDRPTARELLKEL
    ||| |..|||...| ..|. ..|| |.         ..  | . .|.. | | . .        . |. .... |  .|||||| .|. ...
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase MOS1.AA Dicty4 144-192 44 1.1e-13 42.18 In-house 1-50 (277) Show / Hide 
Range on Protein: 144-192
Range on HMM: 1-50/277
Sequence Identity: 44% (22 aa)

FQVEGLIGSGGFGSVFVGKYCGRRVAVKVLRPRRKNA-EAMLQSFRAEVN
 ..| .||.|.||.|. |.  |  ||||.|  .  |. |.||..||.||.
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVH
Kinase MOS1.AA Pkinase_Tyr 144-264 20 1.3e-07 26.35 Pfam 1-132 (270) Show / Hide 
Range on Protein: 144-264
Range on HMM: 1-132/270
Sequence Identity: 20% (28 aa)

FQVEGLIGSGGFGSVFVGKYC------GRRVAVKVLRPRRKNAEAM---LQSFRAEVNAL-YL-KHENIVNVLATSA-VED-FEAGAFIIMEYAGKRNLQ
 .    .|.| ||.|. |..       .  ||||.|..   .|      ...| .|.. .  | .|.|||. ..     ..      .|.|||. . .| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLL

QLINEP---SERLPLARRANFALHIIRALQYTHAHNI
    ..    ..|.. .  .... | ....| ...|.
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNC
Kinase MOS1.AA Pkinase_Tyr 328-408 30 1e-06 23.38 Pfam 192-270 (270) Show / Hide 
Range on Protein: 328-408
Range on HMM: 192-270/270
Sequence Identity: 30% (25 aa)

TTKADIYSFGITLWQMLTRE-TP-YAGENHHVVIFGVVAKDMRPKLPGNENETENDWYRRLITKAWPKQPEDRPTARELLKEL
||| |..|||...| ..|.  .| |.|   . |.  .  .  | . |     .  . |.  ... | ..|||||| .|.. .|
TTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCP---ENCPDEIYDL-MKQCWHYDPEDRPTFSEIHEQL
Kinase MOS1.AA LRRK 144-173 22 5.6e-05 13.54 In-house 1-59 (351) Show / Hide 
Range on Protein: 144-173
Range on HMM: 1-59/351
Sequence Identity: 22% (13 aa)

FQVEGLIGSGGFG-SVFVGKYCG----------------------------RRVAVKVL
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LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKW