Gene NEK1b (Sea Urchin)
NEK1b
Sequence
Protein domains of NEK1b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | NEK1b.AA | NEK-Unclassified | 4-264 | 62 | 7.50000000001e-179 | 597.12 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 4-264 Range on HMM: 1-258/258 Sequence Identity: 62% (168 aa) YDKITTLGQGGGGAVYLVRHQISKLLALKKIQLDEKRKTRTRDAVEREAKILSQLRHPHIVTYHDSFFEEQPESVYLCIAQDYCDGGNLDERIQTAKHRG |||||||||||||||||||||||| ..| |.| | . ||||||||||||||||||| | ||||||||||.||| |||. YDKITTLGQGGGGAVYLVRHQISKRHLVQQISKRKKKKKRQNKII-----ILSQLRHPHIVTYHDSFFEN----AKLFYTQDYCDGGNLDRRIQ--KHRK K--PFDEGRIMQWFIQLVMAVQYIHSKKILHRDLKTQNVFLTKSDVVKLGDFGISRTLEHTVDKAKTCVGTPCYLSPEVCQDQPYNNKSDVWALGCLLYE | ||||||||||.||..|||||||..||.|||||.||.|||..|.| .|||||||...||.|||.|||||.|..||||||||||||.||||.|||..|| KNEPFDEGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYE VCAFEPAFDAHNLLSLYYKIVKGDN-------PTIPSTYSTDLQDLLTFILEKDPDKRPSATTILSQDYV .|..||.||.||....|.||...|| | . .|||||||....|.|......|||||.|..|||. MCTCEPFFDTHNMGEVYMKIKQDDNRLEEALEP-VSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI |
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| Kinase | NEK1b.AA | NEK | 4-264 | 46 | 9.90000000001e-148 | 497.08 | In-house | 1-286 (286) | Show / Hide |
Range on Protein: 4-264 Range on HMM: 1-286/286 Sequence Identity: 46% (134 aa) YDKITTLGQGGGGAVYLVRHQI-SKL-----LALKKIQLDEKRKTRTRDAVE-REAKILSQLRHPHIVTYHDSFFEEQPESVYLCIAQDYCD-GGNLDER |..| ..||| | ||.||... .| ...|||. .. . . ... |..||.||.||.||.|.|||.||| . .||| .||. ||.|... YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQ--NNCLCIVMEYCEGGGDLYQK ---IQTAKHRGKPFDEGRIMQWFIQLVMAVQYIHSK-----KILHRDLKTQNVFLTKSDV----VKLGDFGISRTLEHTVDKAKT-CVGTPCYLSPEVCQ |. |..||.|.| |. ||||...|..|.|.. ||||||.|.||.||||.. ||.||||||. |.||.|.|.| .||||.|.|||||| IKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQ DQPYNNKSDVWALGCLLYEVCAF--EPAFDAH--NLLSLYYKIVKG-DNPTIPST--YSTDLQDLLTFILEKDPDKRPSATTILSQDYV ..|||||||.|.|||.||| |.. ...|.|. |..|||.||.|| . | |||. ||.|||.|... | |||..|||.. ||.. .. NKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | NEK1b.AA | NEK1 | 4-264 | 42 | 4.5e-114 | 385.27 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 4-264 Range on HMM: 1-276/276 Sequence Identity: 42% (119 aa) YDKITTLGQGGGGAVYLVRHQIS-KLLALKKIQLDEKRKTRTRDAVEREAKILSQLRHPHIVTYHDSFFEEQPESVY--LCIAQDYCDGGNLDERIQTAK |..| ..|.| | ..||.| . .....| |.. .| . | .. .|..||. ..|| ||.| .||.|. . | | .||||| | .|. .| YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINV-MKMQEKEREESMNEVAILAKMKHPNIVKYKESFEEN----GCGILYIVMEYCDGGDLMQKINRQK HRGKPFDEGRIMQWFIQLVMAVQYIHSKKILHRDLKTQNVFLT--KSD---------------VVKLGDFGISRTLEHTVDKAKTCVGTPCYLSPEVCQD .||.| | ||.||.|...|...||..||||||.|.||.||| |.. .||||||||.|.| ||.. |.||.||| ||||| || RKGKLFSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQN QPYNNKSDVWALGCLLYEVCAFEPAFDAHNLLSLYYKIVKGDNPTIPSTYSTDLQDLLTFILEKDPDKRPSATTILSQDYV .|||||||.|.||| ||| |. .|.|.|. | ||..| | ||..||..|| |.. . ..| |||...||.. . KPYNNKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI |
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| Kinase | NEK1b.AA | NEK4 | 4-264 | 44 | 1.1e-103 | 350.83 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 4-264 Range on HMM: 1-257/257 Sequence Identity: 44% (118 aa) YDKITTLGQGGGGAVYLVRHQI-SKLLALKKIQLD--EKRKTRTRDAVEREAKILSQLRHPHIVTYHDSFFEEQPESVYLCIAQDYCDGGNLDERIQTAK |. . |.| | |.||||.. | .||..| ..|... | |.||..||||.|| ||.| .|. | . .|.| .|.|| | .. . | YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERK---AAEHEAQLLSQLKHPNIVEYKESW--EIENGQFLYIVMGFCEGGDLYRKLKQQK HRGKPFDEGRIMQWFIQLVMAVQYIHSKKILHRDLKTQNVFLTKSDVVKLGDFGISRTLEHTVDKAKTCVGTPCYLSPEVCQDQPYNNKSDVWALGCLLY .. .| .. ||.| || ||.| |.||||||||||.|||| ..|.||||||| |. | ||| .||| |.|||. .||. |||.|.||| .| --NQFLEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVY EVCAFEPAFDAHNLLSLYYKIVKGDNPTIPSTYSTDLQDLLTFILEKDPDKRPSATTILSQDYV | |||| .. || |.|..| | .| ||.|||.|. .||| |.|||| |. . |. EMITLKHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI |
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| Kinase | NEK1b.AA | NEK8 | 4-264 | 37 | 1.4e-98 | 282.04 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 4-264 Range on HMM: 1-278/278 Sequence Identity: 37% (107 aa) YDKITTLGQGGGGAVYLVRHQI-S--KLLALKKIQLDEKRKTRTRDAVEREAKILSQLRHPHIVTYHDSFFEEQPESVYLCIAQDYCDGGNLDERIQTAK | .| ..|.| | . | | . .| .| | . . . ..| | .|| | || |. | |.| |.. | |. |.|||.| . | .. YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQN-EIQVLSMLQHPNIISYYDHFMEDN----TLMIEMEYADGGTLYQMI--QH HRGKPFDEGR-----------------IMQWFIQLVMAVQYIHSKKILHRDLKTQNVFLTKS-DVVKLGDFGISRTLEHTVDKA--KTCVGTPCYLSPEV ..| | | | | |.| . || ..|.. ||||||||||.|.|.. |||.|||||| . . || ||||.|.||| QQNKLFEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEM CQDQPYNNKSDVWALGCLLYEVCAFEPAFDAHNLLSLYYKIVKG-DNPTIPSTYSTDLQDLLTFILEKDPDKRPSATTILSQDYV |. .|||.|||.||||| ||| | . ||.| ||. | ||. . |.. || .. | . | .||..|||| |... . CEGKPYNQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC |
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| Kinase | NEK1b.AA | S_TKc | 4-264 | 30 | 8.4e-88 | 298.92 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 4-264 Range on HMM: 1-231/231 Sequence Identity: 30% (83 aa) YDKITTLGQGGGGAVYLVRHQI-SKLLALKKIQLDEKRKTRTRDAVEREAKILSQLRHPHIVTYHDSFFEEQPESVYLCIAQDYCDG--GNLDERIQTAK |... ..|.|. | ||..|| .. |.|.| . ..|| .||.. .||.||...|.| . .|.. .|||| |.| ..|. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRG HRGKP--FDEGRIMQWFIQLVMAVQYIHSKKILHRDLKTQNVFLTKSDVVKLGDFGISRTLEHTVDKAKTCVGTPCYLSPEVCQDQPYNN-KSDVWALGC ..|.. |.| .. .. |.. |..|.||..|.||||| .|..|.. ..|..|||..| | .|..||| |..|||. .|. |.|.|..|| RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC LLYEVCAFEPAFDAHNLLSLYYKIVKGDNPTIPSTYSTDLQDLLTFILEKDPDKRPSATTILS-------QDYV .||| .. .| |. .. .. ||. | .. |.. .|.|||.|||.| .| .. ILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | NEK1b.AA | NEK11 | 4-264 | 44 | 1.2e-76 | 260.93 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 4-264 Range on HMM: 1-259/259 Sequence Identity: 44% (118 aa) YDKITTLGQGGGGAVYLVRHQISK----LLALKKIQLDEKRKTRTRDAVEREAKILSQLRHPHIVTYHDSFFEEQPESVYLCIAQDYCDGGNLDERIQTA | || | | |||| . | | || | | | | ||..||.| || || .| || | . || .||.| ||.||| YVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQA-NVEAQLLSRLHHPAIVRFHASFMEQD----NFCIITEYCEGRDLDYRIQEY KHRGKPFDEGRIMQWFIQLVMAVQYIHSKKILHRDLKTQNVFLTKSDVVKLGDFGISRTLEHTVDKAKTCVGTPCYLSPEVCQDQPYNNKSDVWALGCLL |. || | | |. |||||.. | |.| ..||||||| .|.|| | ..|.||||.|| | | | | ||| |.||| . | | |||.|.| |.| KQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFL-KNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACIL YEVCAFEPAFDAHNLLSLYYKIVKGDNPTIPSTYSTDLQDLLTFILEKDPDKRPSATTILSQDYV ||.| .. || | ||. .|| || | .| | .| .. .| |.| |||| || |. YEMCCMDHAFAGSNFLSIVLNIVEGDTPSLPDRYPRELNTIMERMLNKNPSLRPSAIDILKIPYM |
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| Kinase | NEK1b.AA | Pkinase | 4-264 | 25 | 1.8e-73 | 255.23 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 4-264 Range on HMM: 1-293/293 Sequence Identity: 25% (78 aa) YDKITTLGQGGGGAVYLVRHQIS-KLLALKKIQLDEKRKTRTRDAVE-REAKILSQLRHPHIVTYHDSFFEEQPESVYLCIAQDYCDGG----NLDERIQ | .. ..|.|. | ||. .|. . |. |.|.| ...... . .. .|..|. |.||.||...|.| . . .... ..||.|| | ..|. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIS TAKHRGKPF--DEGRIMQWFIQLVMAVQYIHSKKILHRDLKTQNVFLTKSDVV----KLGDFGISRTL-EHTVDKAKTCVGTPCYLSPEVCQ-DQPYNNK | .|...| .| . .. |.. ...|.||..|.||||| .|... . ... |..|||... . . ..| .||| |..|||.. .|.| | T--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK SDVWALGCLLYEVCAFEPAFDAH------NLLSLYYKIVKGDNPTIPSTYS--------------------TDLQDLLTFILEKDPDKRPSATTILSQDY .|.|..||.|||.. .| |. | . . ....| ..... .. . ...|... .|.||| |||.|. || .. VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW V . F |
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| Kinase | NEK1b.AA | STE | 4-264 | 24 | 1.3e-71 | 244.23 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 4-264 Range on HMM: 1-359/359 Sequence Identity: 24% (88 aa) YDKITTLGQGGGGAVYLVRHQ----------------ISKLLALKKIQLDEKRK--------------TRTRDAVEREAKILSQLR--HPHIVTYHDSFF ...| .|.|..| ||. .. .. | |.. |..... . .. ...| ||..... ||.||.|....| WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF EE---QPESVYLCIAQDYCDGGNLDERIQTAKHRGKPFD----------EGRIMQWFIQLVMA-VQYIHSKKILHRDLKTQNVFLTKSDVVKLGDFGISR | . . .|.|. |.||| ||. |.. . .|||.. | | |.. . .|.||..| |||.| .|..| ||| |||.. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG TLEH---------------TVD-KAKTCVGTPCYLSPEVCQ------DQPYNNKSDVWALGCLLYEVCAFEPAF-DAHNLLSLYYKIVK----------- |.. | . | .|.|||| . .||| | |..|. |.|.| |||.. | . .| . | |.. ..... . QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC ---GDNPTIPS-------------------TYSTDLQDLLTFILEKDPDKRPSATTILS--QDYV |. |..|. .| ...| . |.|||.|||.|. |. . IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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| Kinase | NEK1b.AA | CAMK | 9-264 | 19 | 3.8e-68 | 218.44 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 9-264
Range on HMM: 1-425/425
Sequence Identity: 19% (84 aa)
TLGQGGGGAVYLVRHQIS-------------KLLALKKIQLDEKRK-------------------------TRTRDAVEREAKILSQ-------LRHPHI
|||.|. | |.|..| . . | | | . .. ..|. |.|| .|... |.||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VTYHDSFFEEQ-----------------PESVYLCI-AQDYCDGG----NLDERIQTAKHRG-----------KPFDEGRIMQWFIQLVMAVQYIHSKKI
. .. . .. .. .|. .||.|| | ..|. ...| . |.| ..| |.. ||.|.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
LHRDLKTQNVFLTKSD-----------------VVKLGDFGISRTLEHTV-----------------------DKAKTCVGTPCYLS-PEVCQD------
||||| |. |.... .|. ||| .. ... .| ||..|||.| . ||| .
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
--------QPYNNKSDVWALGCLLYEVCAFEPAFDAH-------------NLLSLYYKIVKGDNPTIPSTYST-----------------------DLQD
..|. |.|.|..|..|| .| |.. |. |. || ||. .|. |. . .|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LLTFILEKDPDKRPSATTILSQDYV
|. .|..||.||.... .|. .
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | NEK1b.AA | NEK2 | 4-264 | 31 | 1.2e-64 | 216.59 | In-house | 1-319 (319) | Show / Hide |
Range on Protein: 4-264
Range on HMM: 1-319/319
Sequence Identity: 31% (102 aa)
YDKITTLGQGGGGAVYLVRHQIS-KLLALKKI---QLDEKRKTRTRDAVEREAKILSQLRHPHIVTYHDSFFEEQPESVYLCIAQDYCDGGNLDERIQTA
|. |.|.| | .. ||. |.|. | | ...|| . .. | ||.||.|| || | | . .| ...|. || || | |. .
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKEC----QMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVM--EYCEGGDLSQMIKKC
KHRGKPFDEGRIMQWFIQLVMAVQYIHS------------------KK---ILHRDLKTQNVFLTKSDV-------------------------------
. . ..| | . || | | .| . |||||.| |.|| .
RKERQYMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGS
--------VKLGDFGISRTLEHTVDKAKTCVGTPCYLSPEVCQDQPYNNKSDVWALGCLLYEVCAFEPAFDAHNLLSLYYKIVKGDNPTIPSTYSTDLQD
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PMDYSQVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNE
LLTFILEKDPDKRPSATTILSQDYV
. .| .. |. .||| || . .
IIHFMINVDHYHRPSIEEILQHPQI
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| Kinase | NEK1b.AA | Ciliate-E2-Unclassified | 4-264 | 23 | 2e-59 | 203.72 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 4-264 Range on HMM: 1-352/352 Sequence Identity: 23% (82 aa) YDKITTLGQGGGGAVYLVRHQISKLLA-----LKKIQLDEKRKTRTRDAVEREAKILSQLR-----------------HPHIVTYHDSFFEEQPESVYLC | .| ..|||| | ||...| | .. .|||| . ... .. | .|.|.. .. |||.. ... . ... . ... YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ--NIY IAQDYCDGGNLDERIQTAKH-------------RGKPFDEGRIM-----QWFIQLVMAVQYIHSKK-ILHRDLKTQNVFLTKSD---VVKLGDFGISRTL | .||.||.| . |. |. ..| |.| . ..| |.. . .|.|.|. |.|||.| .|...... .|. |||||. . IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY EHT---------------VDKAKTCVGTPCYL----SPEVCQDQPYNNK----SDVWALGCLLYEVCAFEPAFDAHNLLS---------------LYYKI . ....|..|||.|. .||| | | |... .|.|.||..||| . .. |.. | . .|.. QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN VKGDNPTIPS--------TYSTDLQDLLT----FILEKDPDKRPSATTILSQDYV | |. .|. . | .|... .|.|.|.||... || . IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | NEK1b.AA | Pkinase_Tyr | 45-203 | 28 | 3.5e-26 | 89.28 | Pfam | 47-208 (270) | Show / Hide |
Range on Protein: 45-203 Range on HMM: 47-208/270 Sequence Identity: 28% (47 aa) RDAVEREAKILSQL-RHPHIVTYHDSFF-EEQPESVYLCIAQDYCDGGNLDERIQTAKHRGKPFDEGRIMQWFIQLVMAVQYIHSKKILHRDLKTQNVFL |.. |||||..|| .||.|| .. ...| ...| |. .|.|.. .. .. ..|.. .. |. .| .. .| .||.. |||| . |. . REDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLV TKSDVVKLGDFGISRTL----EHTVDKAKTCVGTPCYLSPEVCQDQPYNNKSDVWALGCLLYEVC |.. ||| .||| .|.. . . |.. . ..||. .. .. |||||. | |..|.. TENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIF |
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| Kinase | NEK1b.AA | TyrKc | 4-263 | 20 | 7e-20 | 73.29 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 4-263 Range on HMM: 1-280/280 Sequence Identity: 20% (61 aa) YDKITTLGQGGGGAVYLVRHQISKLLALKKIQLDEKRKTRTRDAVEREAKILSQL--RHPHIVTYHDSFFEE-------QPESVYLCIAQDYCDGGNLDE .. .|| | | ||. . | |... | | . |||.|...| .||.|| . .. .| |.| |...|.|.. ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEP----LMIVMEYMPHGDLKD RIQTAKHRGKPFDEGRIMQWFIQLVMAVQYIHSKKILHRDLKTQNVFLTKSDVVKLGDFGISRTLEHT--------VDKAKTCVGTP--C---YLSPEVC ... ... . .. .| .|.|||.. |||| . |. ... .|| .||| || ... . ..|. |. ..||. YLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI QDQPYNNKSDVWALGCLLYEVCAF--EPAFDA----HNLLSLYYKIVKGDNPTIPST--------YSTDLQDLLTFILEKDPDKRPSATTILSQDY .. .. |||||. | ...|.. . .| . . .. .. .|. . .| .... .. . . ||..||. ..| .. NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |
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