Gene SAK (Sea Urchin)

SAK

Species: Sea Urchin
Alias: SAK, SPU_016352, Spk188
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: PLK
Subfamily: SAK

Sequence

Name Sequence Type Origin Length Description Download
SAK.AA Protein None 1269 None Fasta, JSON
SAK.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of SAK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SAK.AA SAK 8-261 79 4.7e-200 670.89 In-house 1-254 (254) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-254/254
Sequence Identity: 79% (203 aa)

YQVLNLLGRGGFACVYRAKTISTGQEVAIKMIDKKLMQSSGMATRVKNEVEIHCQLKHPSILELYSYFEDNNYVYLVLELAQNGELLRYLKKKARVFGEE
|||..|||.||||||||||.|.|.||||||||||||||..||..||.||||||||||||||||||.|||||||||||||...|||..||.|...|.|.||
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE

EARQFLEEIVIGLLYLHSHGILHRDLTLANILLTRDMHCKIADFGLAAQLKLPEEQHYTMCGTPNYISPEIATRGPHGLQSDVWSLGCMLYTFLTGTPPF
|||.|...||||.||||||||.||||||.||||||||||||||||||.|||.|.|.||||||||||||||||||..||||||||||||||||.|.|.|||
EARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLIGRPPF

DTEAVKTTLNKVMLAEYIIPTHISMEAKDLINKMLRKDPTERIGLSTVLDHPFM
||.|||.||||||.||||.|.|.||||.|||.|||||.|.|||.|||||.||||
DTDAVKNTLNKVMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase SAK.AA PLK 8-261 46 1.1e-173 569.87 In-house 1-258 (258) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-258/258
Sequence Identity: 46% (121 aa)

YQVLNLLGRGGFACVYRAKTISTGQEVAIKMIDKKLMQSSGMATRVKNEVEIHCQLKHPSILELYSYFEDNNYVYLVLELAQNGELLRYLKKKARVFGEE
|.....||.||||..|... |.|.|..|||...|.|||....  ..|.|.|||.||.||.|......|||...||.|||...|..|..|.|..|... |.
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

EARQFLEEIVIGLLYLHSHGILHRDLTLANILLTRDMHCKIADFGLAAQLKLPEEQHYTMCGTPNYISPEIA--TRGPHGLQSDVWSLGCMLYTFLTGTP
|.|...  || ||.|||.|.|.||||.|.|..|...||.||.|||||..|. ..|...|||||||||.||..  .. .|....|.|||||..||.|.|.|
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFDTEAVKTTLNKVMLAEYIIPTH--ISMEAKDLINKMLRKDPTERIGLSTVLDHPFM
||.|..||.|..... ..|..|.|  ||.||||||.|||...|.||. .. .|.|||.
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase SAK.AA AGC 8-261 25 7.79999999999e-115 297.87 In-house 1-395 (395) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-395/395
Sequence Identity: 25% (101 aa)

YQVLNLLGRGGFACVYRAKTI------STGQEVAIKMIDKKL---MQSSGMATRVKNE------------VEIHCQLK----------HPSILE-LYSYF
...| ..|.|.|  || ..        .||.  |.|...||    .    |  ....|             .|  ...          || |   |.. |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDNNY--VYLVLELAQ---------NG-ELLRYLKK--KARVFGEEEARQFLEE-------IVIGLLYLHS-HGILHRD-LTLANILLTRDMHCKIADFG
.|...  .|.|.|...          | ||. .|..  | ..| ||.|| .. |       || .| |||| .|| ||| | . ||||..| |.|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAAQLKLPE--------------------------------------------------EQHYTMCG--TPNYISPEIATRGPHGLQSDVWS--LGCMLY
|. ...  .                                                  .. .|.||  ||.|..|||     .| . | ||  |||..|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

TFLTGTPPFDTE----------AVKTTLNKVM------LAEYIIP----------THISMEAKDLINKMLRKDPTERIG----------LSTVLDHPFM
 .||| |||  .            . . .|.|        .  .|           ..| ||||||.|.| |||..|.|           . . .||. 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase SAK.AA S_TKc 8-261 36 2.5e-102 347.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-231/231
Sequence Identity: 36% (99 aa)

YQVLNLLGRGGFACVYRAKTISTGQEVAIKMIDKKLMQSSGMATRVKNEVEIHCQLKHPSILELYSYFEDNNYVYLVLELAQN--GELLRYLKKKARV--
|..|...|.|.|..||... ..||..||||.|.           ....|..|. . .|| |  || .|.| ...|.|.|.. .  |.|..|.||. |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FGEEEARQFLEEIVIGLLYLHSHGILHRDLTLANILLTRDMHCKIADFGLAAQLKLPEEQHYTMCGTPNYISPEIATRGPHGL-QSDVWSLGCMLYT
   | | .|| .. .|. .| |.|||||.||||  .||||..  | ||.|||||.||       .|.||||.|..||.    ..|   .|.||.||.|| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

FLTGTPPFDTEAVKTTLNKVMLAEYIIPTHISMEAKDLINKMLRKDPTERIGLSTVLD-------HPFM
.|.| |||.   ......|..          | ||||.|.|.|.|||..|..   .|        ||..
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SAK.AA PLK-Unclassified 8-261 40 3.6e-102 345.74 In-house 1-264 (264) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-264/264
Sequence Identity: 40% (106 aa)

YQVLNLLGRGGFACVYRAKTISTGQEVAIKMIDKKLMQSSGMATRVKNEVEIHCQLKHPSILELYSYFEDNNYVYLVLELAQNGELLRYLKKK------A
|... .|| |||| .| .| |.| .. |.| |.|  ....    . ..| .|| .|.|. |   .  |||. .||..||.  || |  |.|..       
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

RVFGEEEARQFLEEIVIGLLYLHSHGILHRDLTLANILLTRDMHCKIADFGLAAQLKLPEEQHYTMCGTPNYISPEIATRGP--HGLQSDVWSLGCMLYT
 .  | |.. ..  || .| |||...| |||| |.||.|. .|  ||.|||||. |.  .|  .| |||||||.|||    .  |. ..|.||.||.|||
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

FLTGTPPFDTEAVKTTLNKVMLAEYIIP--THISMEAKDLINKMLRKDPTERIGLSTVLDHPFM
.|.| ||| |. ||.|. |.   .|  |   ||| .||||| . |  .| .|  ..  ..|||.
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase SAK.AA CAMK 13-261 23 3.7e-97 313.61 In-house 1-425 (425) Show / Hide 
Range on Protein: 13-261
Range on HMM: 1-425/425
Sequence Identity: 23% (101 aa)

LLGRGGFACVYRAKTISTG------------QEVAIKMIDKKLMQS-------------------------SGMATRVKNEVEIHCQ-------LKHPSI
 ||||.|. |.... ..|.            |.||||.|||| ...                           .  .|..|.||. .       |.|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LELYSYFED-------------------NNYVYLVL---ELAQNGEL----LRYLKKK--------------ARVFGEEEARQFLEEIVIGLLYLHSHGI
. || ..||                   ....|.|.   |....|||    . |....               . | |.|||..   |. .. |.|||.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDLTLANILLTRDM-----------------HCKIADFGLAAQLKL-----------------------PEEQHYTMCGTPNYIS-PEIATR------
 |||| . ||||. ..                   ||.|||.|....                        . .  .|.|||| |.. ||.  .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------GPHGLQSDVWSLGCMLYTFLTGTPPFDTE-------------AVKTTLNKVMLAEYI-IPTH---------------ISME--------AKD
         ..| ..|.||.|..||. |.|.|||. .               . .. |.| ..|  .| .               || |        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LINKMLRKDPTERIGLSTVLDHPFM
||.|||..||..|. .. .|.||.|
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase SAK.AA CAMKL 8-261 32 9.5e-91 289.82 In-house 1-297 (297) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-297/297
Sequence Identity: 32% (97 aa)

YQVLNLLGRGGFACVYRAKT-ISTGQEVAIKMIDKKLMQS-------------SGMATRVKNEVEIHCQLK---HPSILELYSYFEDNNY------VYLV
|...  ||.|.|. |  |.  . ||..||||.|||| ..              . .  |.. |..|. .|.   || |  ||  .|. ..      .|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LELAQNGE--LLRYLKKKA---RVFGEEEARQFLEEIVIGLLYLHSHGILHRDLTLANILLTRDM--HCKIADFGLAAQLK-L---PEEQHYTMCGTPNY
.|....||  |. |..|.    . . |.|||..   || .. |.||||| |||. . ||||. ..    ||.|||.... .     |..   | ||.|.|
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ISPEIATR---GPHGLQSDVWSLGCMLYTFLTGTPPFDTEAVK-------TTLNKVMLAEYIIP--THISMEAKDLINKMLRKDPTERIGLSTVLDHPFM
 .|||  .     .| . |.||.| .||. ..|. ||| . ..       . ..|.|   | .|   |.| ...||| ||| ..|..|. .  .. ||.|
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase SAK.AA Pkinase 8-261 31 2.6e-89 307.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

YQVLNLLGRGGFACVYRAKTISTGQEVAIKMIDKKLMQSSGMATRVK-NEVEIHCQLKHPSILELYSYFEDNNYVYLVLELAQNG----ELLRYLK-KKA
|...  .|.|.|.|||... ..||..||.| |.|.   |.   |... .|..|.  |.|| |..|| .|||....|.|.|....|    .| .|.. .. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RVF--GEEEARQFLEEIVIGLLYLHSHGILHRDLTLANILLTRDMHC----KIADFGLAAQL-KLPEEQHYTMCGTPNYISPEIAT-RGPHGLQSDVWSL
..|   |.|.. .. .|. || |.||.||.|||| ..|||. ...|.    ||.|||||.|.   . .  .| ||||.|..||.   . ..|  .|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCMLYTFLTGTPPFDTE------AVKTTLNKVMLAEYIIPTHIS---------------------MEAKDLINKMLRKDPTERIGLSTVLDHPFM
||.|| .|.| |||. .        .  ....| ...  .   .                      |.||.|...|.|||..|..   .| ||..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase SAK.AA PLK1 8-261 40 1.4e-85 281.27 In-house 1-253 (253) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-253/253
Sequence Identity: 40% (102 aa)

YQVLNLLGRGGFACVYRAKTISTGQEVAIKMIDKKLMQSSGMATRVKNEVEIHCQLKHPSILELYSYFEDNNYVYLVLELAQNGELLRYLKKKARVFGEE
|.    ||.||||  |  .  .| . .| |.. |.|.  .    ..  |..|| ||.|. | .....|||...||.|||| .   |.  |.|. .   | 
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLME-LHKRRKAITEP

EARQFLEEIVIGLLYLHSHGILHRDLTLANILLTRDMHCKIADFGLAAQLKLPEEQHYTMCGTPNYISPEIATRGPHGLQSDVWSLGCMLYTFLTGTPPF
|.| ..  || | .|||   |.|||| | |. |  ... || ||||| ..    |.  |.||||||| ||. ..  |    |.||.||..|. | | |||
ECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPF

DTEAVKTTLNKVMLAEYIIPTHISMEAKDLINKMLRKDPTERIGLSTVLDHPFM
.|...| |  ..  .|| ||.|||  |..|| ||| .|||.|   . ||   |.
ETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase SAK.AA Ciliate-E2 8-261 24 8.6e-85 288.01 In-house 1-365 (365) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

YQVLNLLGRGGFACVYRAKTISTG-----------------------QEVAIKMIDKKLMQSSGMATRVKNEVE----------IHCQLKHPSILELYSY
| .....|.|.|..||..| ....                       ...|.|.. |.  ..  .  .. .|..          |  ||.|| |...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--DNNYVYLVLELAQNGELLRYLK--KKARVFG--------EEEARQFLEEIV---------------IGLLYLHSHG-ILHRDLTLANILLTRDMHC
|.  |.|..|||.|..| |.|. |.|  || | .         |.|.... ..|.                .| |||| . |.|||. . |||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGLAAQLKLP-------------------------------EEQHYTMCGTPNYISPEIATRGP---------HGLQSDVWSLGCMLYTFLTGTPP
||.||||. ... .                               .....| ||||.| .|||  ...         .. ..|.||||..|| .|.| ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FDTEAVKTTLNKVMLAEYIIP------------------THISMEAKDLINK----MLRKDPTERIG-LSTVLDHPFM
|        ... .  .. .|                   ..| |.||||.|    || ||| .||.  . .|.||..
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase SAK.AA PLK2 8-261 38 2.5e-82 264.9 In-house 1-257 (257) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-257/257
Sequence Identity: 38% (100 aa)

YQVLNLLGRGGFACVYRAKTISTGQEVAIKMIDKKLMQSSGMATRVKNEVEIHCQLKHPSILELYSYFEDNNYVYLVLELAQN----GELLRYLKKKARV
|    ||| ||||  | .  ..|.   |.| . .           . .|.|.| ||.|. | . . .|||   .|..||.         ..  .|   ..
YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVR-HH

FGEEEARQFLEEIVIGLLYLHSHGILHRDLTLANILLTRDMHCKIADFGLAAQLKLPEEQHYTMCGTPNYISPEIATRGPHGLQSDVWSLGCMLYTFLTG
  | | | ..  || || |||...|.|||| | |  ..  |  || |||||| |  .|. | |||||||||.||.  |  |.  ||.|.|||  || |.|
LTEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVLNRQGHSCESDIWALGCIMYTMLCG

TPPFDTEAVKTTLNKVMLAEYIIPTHISMEAKDLINKMLRKDPTERIGLSTVLDHPFM
.||| |   | |   .  . | .||| |  |. || .||..|| .|  |  ...| | 
RPPFETANLKETYRCIRHNHYHMPTHLSPPARHLIARMLSPDPEDRPSLDHIIRHDFF
Kinase SAK.AA ULK 8-261 29 2.5e-79 269.86 In-house 1-329 (329) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-329/329
Sequence Identity: 29% (96 aa)

YQVLNLLGRGGFACVYRAKTIST----GQEVAIKMIDKK-LMQSSGMAT------RVKNEVEIHCQLK--------HPSILELYSYFEDN--NYVYLVLE
|.. . || | |. ||... . |    .. ||.|||||. . |.. ...       .|||..|  .||        || | .|| .||.   |..|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LAQNGELLRYLKKKAR---------VFGEEEARQFLEEIVIGLLYLHSHGILHRDLTLANILLTRD------------MHCKIADFGLAAQLKLP---EE
. . | |  |.||. .          . |.||.||.  |. |. .||.|.| |||. ..|||.. .            ...||||||.| ..  .   ..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

QHYTMC------GTPNYISPEIAT----RGPHG-LQSDVWSLGCMLYTFLTGTPPFDTEAVKTTLNKVMLAEYIIP--------------------THIS
. .|.       ||| | .|.|      . |..   .|.|||||..|  |.| ||| .    .. .. .  .. .|                     .||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

MEAKDLINKMLRKDPTERIGLSTVLDHPFM
 | |||| .|| .|...||    ...||..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase SAK.AA Pkinase_Tyr 8-154 31 1.1e-28 97.79 Pfam 1-158 (270) Show / Hide 
Range on Protein: 8-154
Range on HMM: 1-158/270
Sequence Identity: 31% (50 aa)

YQVLNLLGRGGFACVYRAKTI----STGQEVAIKMIDKKLMQS-SGMATRVKNEVEIHCQL-KHPSILELYSYFE-DNNY--VYLVLELAQNGELLRYLK
 . .  ||.| |  ||...      .|...||.||.  . |..   .     .|..| .|| .|| |. ||     .     .|.|.|....| || ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KK---ARVFGEEEARQFLEEIVIGLLYLHSHGILHRDLTLANILLTRDMHCKIADFGLA
|.    . .  ..  |.  .|  |. ||.|... ||||   |.|.|.....||.|||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase SAK.AA TyrKc 8-261 22 5.7e-17 51.73 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YQVLNLLGRGGFACVYRAKTISTGQEVAIKMIDKKLMQSSGMATRVKNEVEIHCQL--KHPSILELYSYFEDN-------NYVYLVLELAQNGELLRYLK
 . .  ||.| |  ||... .   ..||.||. .             .| .| |.|  .|| |. || .  .          ...|.|.. .| |. ||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KKARVFGEEEARQFLEEIVIGLLYLHSHGILHRDLTLANILLTRDMHCKIADFGLAAQLKLP-----EEQHYTM----CGTP----NYISPEIATRGPHG
|. . .  ..  .|   |  |  ||||... ||||   |.|.... ..||.||||.  ..       ... |..    .|         .||    |   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

LQSDVWSLGCMLY-TFLTGTPPFDT-----EAVKTTLNKVMLAEYIIPTHI---------SMEAKDLINKMLRKDPTERIGLSTVLDHPFM
 .||||| | ...  |  | .|           .  ...|.  ..  . .          . |  ... .  . || .|   |..  | ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
POLO_box SAK.AA POLO_box 979-1021 23 0.000226 19.75 Pfam 1-47 (74) Show / Hide 
Range on Protein: 979-1021
Range on HMM: 1-47/74
Sequence Identity: 23% (11 aa)

FVPNIGWASQMSSGEVRVQ-YNDGSMILVHAATS-TIKYMD--SQGK
.  . |.  |.| | | |. .||.. |.... .  .. |.|   ...
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQ
POLO_box SAK.AA POLO_box 1192-1256 22 4.7e-07 29.66 Pfam 1-74 (74) Show / Hide 
Range on Protein: 1192-1256
Range on HMM: 1-74/74
Sequence Identity: 22% (17 aa)

FVPNIGWASQMSSGEVRVQ-YNDGSMILVHATTS-TIKYMD--SQGKGQSYGRNAVL-----PSHIREKLLHMP
.  . |.  |.| | | |. .||.. |......  .. |.|   ... | |  . .|     |. ...|| .. 
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK