Gene SCYL1 (Sea Urchin)

SCYL1

Species: Sea Urchin
Alias: Spk192, SPU_007733, SCYL1
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: SCY1

Sequence

Name Sequence Type Origin Length Description Download
SCYL1.AA Protein None 1362 None Fasta, JSON
SCYL1.kin_dom Protein Kinase Domain None 412 None Fasta, JSON

Protein domain

Protein domains of SCYL1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SCYL1.AA SCY1 30-260 25 1.1e-72 247.76 In-house 1-337 (337) Show / Hide 
Range on Protein: 30-260
Range on HMM: 1-337/337
Sequence Identity: 25% (86 aa)

WTLHQGKRKANGEPVSVFMVDLK--------SHSESIVQLAKSAHKRLKTLRHPNFLLYVDGLETENV--IYVVTEEVTPLGTFLKTNAP----------
|..|.|..|..|. .||| .| |        | .|.|....|.. ||||.||||| | |...||..    .|...| ..||.. ||.             
WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQKTQ

---------------------KESTISWGLYQVVKGLSFLHNDCKLKHNNVNLSCVFVTRAGEWKLGA---------VDYITPSEGEGSTNPDKGLRSL-
                     .|. ..||..|....||||||||.. |||.. . .||...|.||.|           |. ..........|.  .. . 
DVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMPWFPCQEWR

-------------EK-----YNPPEMTDARTRKRP--------------CPWAADMWGLGCLIWEVFNGTLPRTSSLKAL-------------------G
             .|     ...|. .. ..   .              | ||.||..||||||.|.||. |... .. .                   .
EMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWNAMSHCWWD

KIPKHLVPN----YCELVGANPISRPNPAKFIESCQN
.||| |       ||.|....|..||.|..|...|  
HIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF
Kinase SCYL1.AA S_TKc 30-270 13 2e-06 -82.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-270
Range on HMM: 1-231/231
Sequence Identity: 13% (38 aa)

WTL------------HQGKRKANGEPVSVFMVDLKSHSESIVQLAKSAHKRLKTLRHPNFLLYVDGLETENVIYVVTEEVT----PLGTFLKTNAP----
...            .... |  |. | . ...         . ...  . ||  .|||   . |  .. . .|.|.| .      | ...| . .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

---KESTISWGLYQVVKGLSFLHNDCKLKHNNVNLSCVFVTRAGEWKLG----AVDYITPSEGEGSTNPDKGLRSLEKYNPPEMTDARTRKRPCPW-AAD
    | ..   .||....| ..|.  .  |  .  . .....  . |..    |  .             . .     | .||.        .    ..|
FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL-------GYGKCKCD

MWGLGCLIWEVFNGTLPRTSSLKALGKIPKHLVPNYCELVGANPISRPNPAK-FIESCQN--------SGGFMK-------NSFV
.| .||...| . |  |    .... |. .                 . .|| ||. | .            ..         ..
WWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SCYL1.AA Dicty3 201-221 42 0.000324 9.6 In-house 279-299 (351) Show / Hide 
Range on Protein: 201-221
Range on HMM: 279-299/351
Sequence Identity: 42% (9 aa)

DMWGLGCLIWEVFNGTLPRTS
|.|.|||..|| . | |. ..
DIWSLGCTVWEMVGGNLCHCE
Kinase SCYL1.AA Fused 200-218 52 0.000826 8.73 In-house 178-196 (251) Show / Hide 
Range on Protein: 200-218
Range on HMM: 178-196/251
Sequence Identity: 52% (10 aa)

ADMWGLGCLIWEVFNGTLP
|||| ||| ..| . |. |
ADMWSLGCILYELMVGQPP
Kinase SCYL1.AA Ciliate-C4 196-215 45 0.001991 6.46 In-house 249-268 (361) Show / Hide 
Range on Protein: 196-215
Range on HMM: 249-268/361
Sequence Identity: 45% (9 aa)

CPWAADMWGLGCLIWEVFNG
|||  |.| .||.. |.. |
CPWSIDIWSMGCVMMEIITG
Kinase SCYL1.AA FGTK 199-215 58 0.002188 7.71 In-house 190-206 (302) Show / Hide 
Range on Protein: 199-215
Range on HMM: 190-206/302
Sequence Identity: 58% (10 aa)

AADMWGLGCLIWEVFNG
| | | || .|||.||.
ASDVWSLGVTIWEIFNQ
Kinase SCYL1.AA Ciliate-D1 201-219 36 0.00228 11.71 In-house 1-19 (19) Show / Hide 
Range on Protein: 201-219
Range on HMM: 1-19/19
Sequence Identity: 36% (7 aa)

DMWGLGCLIWEVFNGTLPR
|.| .||...| ..|  | 
DIWSFGCILYEMLFGQPPF
Kinase SCYL1.AA KIS 196-215 45 0.002301 5.08 In-house 371-390 (473) Show / Hide 
Range on Protein: 196-215
Range on HMM: 371-390/473
Sequence Identity: 45% (9 aa)

CPWAADMWGLGCLIWEVFNG
|  |.|.| ||| | . . |
CTHAVDIWSLGCIIVRMYTG
Kinase SCYL1.AA NZAK 201-220 40 0.002916 6.24 In-house 254-273 (329) Show / Hide 
Range on Protein: 201-220
Range on HMM: 254-273/329
Sequence Identity: 40% (8 aa)

DMWGLGCLIWEVFNGTLPRT
| | .||..|..| . .| |
DVWSFGCTVWQMFGYNPPNT
Kinase SCYL1.AA Pkinase 199-218 40 0.003602 12.29 Pfam 192-211 (293) Show / Hide 
Range on Protein: 199-218
Range on HMM: 192-211/293
Sequence Identity: 40% (8 aa)

AADMWGLGCLIWEVFNGTLP
..|||..||...|...| .|
KVDMWSCGCILYEMLCGRPP
Kinase SCYL1.AA Akt 199-218 47 0.0112 4.29 In-house 182-202 (264) Show / Hide 
Range on Protein: 199-218
Range on HMM: 182-202/264
Sequence Identity: 47% (10 aa)

AADMWG-LGCLIWEVFNGTLP
|.| || |||...|   | .|
AVDWWGSLGCVMYEMMCGRPP
Kinase SCYL1.AA STE 200-218 47 0.035357 3.64 In-house 249-267 (359) Show / Hide 
Range on Protein: 200-218
Range on HMM: 249-267/359
Sequence Identity: 47% (9 aa)

ADMWGLGCLIWEVFNGTLP
.|.| |||.|.|  .|  |
CDIWSLGCTIIEMATGKPP
Kinase SCYL1.AA NZAK 69-129 25 0.050845 2.0 In-house 52-122 (329) Show / Hide 
Range on Protein: 69-129
Range on HMM: 52-122/329
Sequence Identity: 25% (18 aa)

LKTLRHPNFLLYVD----GLETENVIYVVTEEVT--PLGTFL----KTNAPKESTISWGLYQVVKGLSFLH
|  .||.|   |.       | .| .... | .    |  ||    |    ||. |   .  .....|.||
LEKIRHFNIPRYYSACIKHAEDDNYHCIYMEWMEGGNLTQFLMNDKKQLRFKEHRIIKMIADIAETMSYLH
Kinase SCYL1.AA Fused 70-95 30 0.129937 1.07 In-house 53-78 (251) Show / Hide 
Range on Protein: 70-95
Range on HMM: 53-78/251
Sequence Identity: 30% (8 aa)

KTLRHPNFLLYVDGLETENVIYVVTE
. ..||.    .|  ||.  . |||.
RRMHHPHIIHMIDSFETDKEVVVVTD
Kinase SCYL1.AA STE 110-130 40 0.157371 1.32 In-house 149-170 (359) Show / Hide 
Range on Protein: 110-130
Range on HMM: 149-170/359
Sequence Identity: 40% (9 aa)

KESTISWGLYQVVKG-LSFLHN
.|| |.. ..|..|| |..||.
PESQIAYICRQILKGLLYYLHS
Kinase SCYL1.AA Pkinase 69-95 40 2.890845 2.02 Pfam 54-80 (293) Show / Hide 
Range on Protein: 69-95
Range on HMM: 54-80/293
Sequence Identity: 40% (11 aa)

LKTLRHPNFLLYVDGLETENVIYVVTE
.| |.||| . . |  |... ||.|.|
MKRLNHPNIVRLYDWFEDKDHIYMVME
Kinase SCYL1.AA HEAT 219-233 26 56.37474 0.31 Pfam 17-31 (31) Show / Hide 
Range on Protein: 219-233
Range on HMM: 17-31/31
Sequence Identity: 26% (4 aa)

RTSSLKALGKIPKHL
| .....||.. .|.
REAACWCLGQLCEHC
HEAT SCYL1.AA HEAT 347-363 23 20.962054 1.8 Pfam 1-17 (31) Show / Hide 
Range on Protein: 347-363
Range on HMM: 1-17/31
Sequence Identity: 23% (4 aa)

VVPIVVKLFSSTDRNTR
..|...|.....| . |
ILPHLLKCLNDPDWEVR
Kinase SCYL1.AA SCY1 415-645 25 4e-72 245.91 In-house 1-337 (337) Show / Hide 
Range on Protein: 415-645
Range on HMM: 1-337/337
Sequence Identity: 25% (86 aa)

WTLHQGKRKANGEPVSVFMVDLK--------SHSESIVQLAKSAHKRLKTLRHPNFLLYVDGLETENV--IYVVTEEVTPLGTFLKTNAP----------
|..|.|..|..|. .||| .| |        | .|.|....|.. ||||.||||| | |...||..    .|...| ..||.. ||.             
WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQKTQ

---------------------KESTISWGLYQVVKGLSFLHNDCKLKHNNVNLSCVFVTRAGEWKLGA---------VDYITPSEGEGSTNPDKGLRSL-
                     .|. ..||..|....||||||||.. |||.. . .||...|.||.|           |. ..........|.  .. . 
DVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMPWFPCQEWR

-------------EK-----YNPPEMTDVRARKRP--------------CPWAADMWGLGCLIWEVFNGTLPRTSSLKAL-------------------G
             .|     ...|. ....    .              | ||.||..||||||.|.||. |... .. .                   .
EMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWNAMSHCWWD

KIPKHLVPN----YCELVGANPISRPNPAKFIESCQN
.||| |       ||.|....|..||.|..|...|  
HIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF
Kinase SCYL1.AA Dicty3 586-606 42 0.000324 9.6 In-house 279-299 (351) Show / Hide 
Range on Protein: 586-606
Range on HMM: 279-299/351
Sequence Identity: 42% (9 aa)

DMWGLGCLIWEVFNGTLPRTS
|.|.|||..|| . | |. ..
DIWSLGCTVWEMVGGNLCHCE
Kinase SCYL1.AA Fused 585-603 52 0.000826 8.73 In-house 178-196 (251) Show / Hide 
Range on Protein: 585-603
Range on HMM: 178-196/251
Sequence Identity: 52% (10 aa)

ADMWGLGCLIWEVFNGTLP
|||| ||| ..| . |. |
ADMWSLGCILYELMVGQPP
Kinase SCYL1.AA Ciliate-C4 581-600 45 0.001991 6.46 In-house 249-268 (361) Show / Hide 
Range on Protein: 581-600
Range on HMM: 249-268/361
Sequence Identity: 45% (9 aa)

CPWAADMWGLGCLIWEVFNG
|||  |.| .||.. |.. |
CPWSIDIWSMGCVMMEIITG
Kinase SCYL1.AA FGTK 584-600 58 0.002188 7.71 In-house 190-206 (302) Show / Hide 
Range on Protein: 584-600
Range on HMM: 190-206/302
Sequence Identity: 58% (10 aa)

AADMWGLGCLIWEVFNG
| | | || .|||.||.
ASDVWSLGVTIWEIFNQ
Kinase SCYL1.AA Ciliate-D1 586-604 36 0.00228 11.71 In-house 1-19 (19) Show / Hide 
Range on Protein: 586-604
Range on HMM: 1-19/19
Sequence Identity: 36% (7 aa)

DMWGLGCLIWEVFNGTLPR
|.| .||...| ..|  | 
DIWSFGCILYEMLFGQPPF
Kinase SCYL1.AA KIS 581-600 45 0.002301 5.08 In-house 371-390 (473) Show / Hide 
Range on Protein: 581-600
Range on HMM: 371-390/473
Sequence Identity: 45% (9 aa)

CPWAADMWGLGCLIWEVFNG
|  |.|.| ||| | . . |
CTHAVDIWSLGCIIVRMYTG
Kinase SCYL1.AA NZAK 586-605 40 0.002916 6.24 In-house 254-273 (329) Show / Hide 
Range on Protein: 586-605
Range on HMM: 254-273/329
Sequence Identity: 40% (8 aa)

DMWGLGCLIWEVFNGTLPRT
| | .||..|..| . .| |
DVWSFGCTVWQMFGYNPPNT
Kinase SCYL1.AA Pkinase 584-603 40 0.003602 12.29 Pfam 192-211 (293) Show / Hide 
Range on Protein: 584-603
Range on HMM: 192-211/293
Sequence Identity: 40% (8 aa)

AADMWGLGCLIWEVFNGTLP
..|||..||...|...| .|
KVDMWSCGCILYEMLCGRPP
Kinase SCYL1.AA Akt 584-603 47 0.0112 4.29 In-house 182-202 (264) Show / Hide 
Range on Protein: 584-603
Range on HMM: 182-202/264
Sequence Identity: 47% (10 aa)

AADMWG-LGCLIWEVFNGTLP
|.| || |||...|   | .|
AVDWWGSLGCVMYEMMCGRPP
Kinase SCYL1.AA STE 585-603 47 0.035357 3.64 In-house 249-267 (359) Show / Hide 
Range on Protein: 585-603
Range on HMM: 249-267/359
Sequence Identity: 47% (9 aa)

ADMWGLGCLIWEVFNGTLP
.|.| |||.|.|  .|  |
CDIWSLGCTIIEMATGKPP
Kinase SCYL1.AA NZAK 454-514 25 0.050845 2.0 In-house 52-122 (329) Show / Hide 
Range on Protein: 454-514
Range on HMM: 52-122/329
Sequence Identity: 25% (18 aa)

LKTLRHPNFLLYVD----GLETENVIYVVTEEVT--PLGTFL----KTNAPKESTISWGLYQVVKGLSFLH
|  .||.|   |.       | .| .... | .    |  ||    |    ||. |   .  .....|.||
LEKIRHFNIPRYYSACIKHAEDDNYHCIYMEWMEGGNLTQFLMNDKKQLRFKEHRIIKMIADIAETMSYLH
Kinase SCYL1.AA Fused 455-480 30 0.129937 1.07 In-house 53-78 (251) Show / Hide 
Range on Protein: 455-480
Range on HMM: 53-78/251
Sequence Identity: 30% (8 aa)

KTLRHPNFLLYVDGLETENVIYVVTE
. ..||.    .|  ||.  . |||.
RRMHHPHIIHMIDSFETDKEVVVVTD
Kinase SCYL1.AA STE 495-515 40 0.157371 1.32 In-house 149-170 (359) Show / Hide 
Range on Protein: 495-515
Range on HMM: 149-170/359
Sequence Identity: 40% (9 aa)

KESTISWGLYQVVKG-LSFLHN
.|| |.. ..|..|| |..||.
PESQIAYICRQILKGLLYYLHS
Kinase SCYL1.AA Pkinase 454-480 40 2.890845 2.02 Pfam 54-80 (293) Show / Hide 
Range on Protein: 454-480
Range on HMM: 54-80/293
Sequence Identity: 40% (11 aa)

LKTLRHPNFLLYVDGLETENVIYVVTE
.| |.||| . . |  |... ||.|.|
MKRLNHPNIVRLYDWFEDKDHIYMVME
Kinase SCYL1.AA HEAT 604-618 26 56.37474 0.31 Pfam 17-31 (31) Show / Hide 
Range on Protein: 604-618
Range on HMM: 17-31/31
Sequence Identity: 26% (4 aa)

RTSSLKALGKIPKHL
| .....||.. .|.
REAACWCLGQLCEHC
HEAT SCYL1.AA HEAT 732-762 25 0.012228 13.0 Pfam 1-31 (31) Show / Hide 
Range on Protein: 732-762
Range on HMM: 1-31/31
Sequence Identity: 25% (8 aa)

IVPIVVKLFSSTDRNTRVKLLQQMDQFIEHL
|.|...|.....| . |   .. . |..||.
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT SCYL1.AA HEAT 771-801 25 4.2e-05 21.55 Pfam 1-31 (31) Show / Hide 
Range on Protein: 771-801
Range on HMM: 1-31/31
Sequence Identity: 25% (8 aa)

IFPHICHGFNDTVPVIRENTVKAMLLLASKL
|.||.....||... .||......  |....
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT SCYL1.AA HEAT 810-841 25 9.56905 2.98 Pfam 1-31 (31) Show / Hide 
Range on Protein: 810-841
Range on HMM: 1-31/31
Sequence Identity: 25% (8 aa)

LLKHFARLQAKDEQGGIRTNTTICLGKLAGYL
.| |. ..   |.   .| ..  |||.|. ..
ILPHLLKCLN-DPDWEVREAACWCLGQLCEHC
HEAT SCYL1.AA HEAT 889-919 29 8.6e-05 20.45 Pfam 1-31 (31) Show / Hide 
Range on Protein: 889-919
Range on HMM: 1-31/31
Sequence Identity: 29% (9 aa)

VLPTLCTLTVDPDQGVRQNAFKAIKIFLGKL
.||.|...  |||  ||..|..... .. ..
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
Kinase SCYL1.AA SCY1 952-1341 23 7.2e-123 414.5 In-house 1-337 (337) Show / Hide 
Range on Protein: 952-1341
Range on HMM: 1-337/337
Sequence Identity: 23% (95 aa)

WAMTSLTSRLYRGGGTKPAAPGTGGPQQAKPDTAASKPAPAKDERPSSMTRVDGSRDRDSDSDYGNEGGKEGDADGWNDNDNWGNMEEEEETTTAQETKE
|.....|.. |.|..................|..................|..                                               
WKIHNGTKK-YTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRLKRLR-----------------------------------------------

TSEWDSQGWGDDYDDDMDSLETPAPKSSKSTSYATSSISSSASTAKSKSSALKLGGTKKTQDVDFG------------DWGLDESSVDRKPIKTSSKLSK
             .........|...|.....|||..|.........|....|...|.||||||||            ||.|||..|..........||.
-------------HPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQKTQDVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSF

SQSGSERSTPKGSPKKTMRNEADLGGWDDDDDDAGGWGSMDAVADDDGGGGGGGWGDDEEWGAMDDLSVSSTKPAQKSKPTSKPPPGWGDNLDFAEDKSH
.............|.....|... .....||||||||| ||.|.|...|.....|....||..||..|||||||..|..|...|.|.|... ...||. |
LHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWG-MDFVCDIQNGNPQMPWFPCQEWREMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQ-H

TPASSYNWGQEQETTPDQDFFGATARSTTTTSKKSLQTTKKSSPIKQTASSDTSGWGAKDSGWDDDGWGSVDNEGGSNDSGLSKAELAKKKREERRLQRE
||| ||||||||..|...|.|............|..|.|..|.| ..|.......|.|....|.|..........|.....|..............||..
TPA-SYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNP-YSTFHRYMEQWNAMSHCWWDHIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHC

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