Gene Spk396 (Sea Urchin)

Spk396

Species: Sea Urchin
Alias: Spk396
External Links:
Annotation:

Classification

Group: Other
Family: urch
Subfamily: urchA

Sequence

Name Sequence Type Origin Length Description Download
Spk396.AA Protein None 538 None Fasta, JSON
Spk396.kin_dom Protein Kinase Domain None 163 None Fasta, JSON

Protein domain

Protein domains of Spk396.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Spk396.AA urchA 293-491 54 5.6e-146 473.8 In-house 1-208 (208) Show / Hide 
Range on Protein: 293-491
Range on HMM: 1-208/208
Sequence Identity: 54% (113 aa)

LGSGANGTVHLYRHRATDHPIALKTFELPNDIKAMTRKVNAIQSEAFILDVLGREDCFPTFLGCLEISTGKIGLAMDFVGDTMTGES----WTLSH--GM
||.|..|||||||||.||||.|||..|||...|.|.||....|.|..|..|||.|..||||.||.||...|.|.||.|.||.|||||    |.|..  .|
LGRGVYGTVHLYRHRQTDHPVALKVIELPKEYKKMRRKIECFQNEMQIHQVLGCEPWFPTFYGCCEICEDKVGMAMEFCGDEMTGESYTITWCLDKAMEM

RKLALSQHDWFALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDRPY---FYRFSDEVKEKYRRREVYVHIAPECVLDDVL
|..||....|....||||..|...||||||.|||||||||.|||..|||.|.|.|||.||||..|.   ...|. . |. || .  . ||||||.||   
RQPALTRDQWMNVMLDIAEGLKVMHEKGFLCNDLKEDNCLVRKTEFGRWRAKIIDFGWACPCQMPFPACRMHFDQRQKQFYRYCHRCCHIAPECALDAQP

TSVSSDVF
 | ||||.
CSTSSDVY
Kinase Spk396.AA urch 293-494 38 1.2e-111 377.23 In-house 1-217 (217) Show / Hide 
Range on Protein: 293-494
Range on HMM: 1-217/217
Sequence Identity: 38% (84 aa)

LGSGANGTVHLYRHRATDHPIALKTFELPNDIKAMTR--------KVNAIQSEAFILDVLGREDCFPTFLGCLEISTGKIGLAMDFVGDTMTGES----W
.|.|..|.|||||||.|..|.|.|....|.....|..        .. ....||...........||.|.||..|. ....|.|.|.||..||.|    |
IGRGTYGRVHLYRHRQTKQPVAIKMPCWPQNYTDMNEMEMEEWKANHERFTKEAMVHQLMSGHPYFPKFYGCVDID-DDLCLVMEFIGDKKTGKSYPLHW

TLSH---GMRKLALSQHDWFALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDRPY-FYRFSDEVKEKYRRREVYVHIAPE
....   .|....||...|.. |.||.... ..|..|||.|||||||.||.|...|||.|||.|||..|....|. ...|.||... |.....|.|||||
CIHKSRMCMPNPHLSKWNWLNIAEDIVHGMMAMHDHGFLHNDLKEDNVLLEKRGHGRWHAVIIDFGWVCTMTMPFKMMHFPDEEMREYMHGHGYCHIAPE

CVLDDVLTSVSSDVFQLG
||||   .|..|||. .|
CVLDGQPCSIASDVYSVG
Kinase Spk396.AA urch-unclassified 293-494 30 2e-45 157.23 In-house 1-215 (215) Show / Hide 
Range on Protein: 293-494
Range on HMM: 1-215/215
Sequence Identity: 30% (65 aa)

LGSGANGTVHLYRHRATDHPIALK-TFELPND-IKAMTRK---VN--AIQSEAFILDVLGREDCFPTFLGCLEISTGKIGLAMDFVGDTMTGESWTLSHG
.| |. | | ..|| ..  | . |   |. || .  | ..   ..   |  || .  ...    ||  .|  ..  .  ...|.| ||  |.   .|.  
IGKGTFGKVFMMRHQREAVPVKVKMIHEHHNDYDYEMRMQNKLLMHERIMKEAMVHRLFADHPYFPRCYGMVKH-EDCPCIVMEFLGDKQTYTVYPLCQW

MRKLA-----LSQHDWFALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPT-GRWQAVIVDFGLACPCDR-PYFYRFSDEVKEKYRRREVYVHIAPECV
          || | |.  ..|| . .   ||.. | |||| .| ||.. .   || | | |||.. . ..   . .|||. .. |.   .| |.||| |
IHERHKSNPALSKHHWINICMDICHGMHAMHEMDLLHNDLKSNNILLQWCDHDQRWHAYIIDFGMISTMTMPHKQRNFSDHEMREYMMGKIYHHMAPEIV

LDDVLTSVSSDVFQLG
|.   ||| ||.. ||
LYGQPTSVYSDIYSLG
Kinase Spk396.AA urchC 337-497 28 7.4e-18 54.21 In-house 57-223 (223) Show / Hide 
Range on Protein: 337-497
Range on HMM: 57-223/223
Sequence Identity: 28% (50 aa)

EAFILDVLGREDCFPTFLGCLEISTGKIGLAMDFVGDTMTGESWTLSHGMR-------KLALSQHDWFALALDIAKSLGRIHEKGFLMNDLKEDNCLL--
|| .. .. .   || ..| . |  . . .   |.||  .| .. |   |         . ..     | | || .    .|  | | || | || ||  
EARVGQMMSTCPYFPRMYGTVMID-ENMCIVTEFIGDKQQGKVYMLHDAMCPRKGCDPIPYVQKWNMVAIAEDIIRGVHFMHDFGLLHNDIKDDNVLLEH

RKTPTGRWQAVIVDFGLACPCDRP-YFYRFSDEVKEKYRRREVYVHIAPECVLD--DVLTSVSSDVFQLGRLL
||    || ..|.| |.      | ..  |.| . .  ..   ..||||| |||     .||.||..  | .|
RKE---RWHGCIIDMGMVSTMAYPPHQRGFNDVMPDH-QKLYGFIHIAPE-VLDIDGCQVSVASDIYSVGVIL
Kinase Spk396.AA urchB 350-494 38 3.4e-16 54.81 In-house 72-212 (212) Show / Hide 
Range on Protein: 350-494
Range on HMM: 72-212/212
Sequence Identity: 38% (56 aa)

FPTFLGCLEISTGKIGLAMDFVGDTMTGESWTLSHGMRKLALSQHDWFALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCD
|| |.| | |      .|  |||   ||  . |        ||       | || | .  .|  | | |||| || || |    |. |||.|||..    
FPKFWGTLDIDN-DLCQAQEFVGCKKTGIGYPL---HEPPPLSMCNVVDIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGH-RYHAVIIDFGMVSTIT

RPY-FYRFSDEVKEKYRRREVYVHIAPECVLDDVLTSVSSDVFQLG
 |        |.|  |   |    |||| .|..  ||.|||||  |
APLKMVEVPKELKMAYVHGEEADYIAPEVILHGQSTSISSDVFSVG
Kinase Spk396.AA TESK 388-451 39 3.9e-12 34.18 In-house 88-155 (292) Show / Hide 
Range on Protein: 388-451
Range on HMM: 88-155/292
Sequence Identity: 39% (27 aa)

KLALSQHDWFALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA----CPCDRP
.|.||      ||.|||. .  .|.||    ||   ||| |. .   ..||. |||||    |  | |
ELHLSWTQKIHLAYDIARGMSYLHSKGVFHRDLTSKNCLVRQRDNNQYEAVVGDFGLARVLGCMPDPP
Kinase Spk396.AA LISK 399-445 38 2.1e-08 23.2 In-house 106-152 (296) Show / Hide 
Range on Protein: 399-445
Range on HMM: 106-152/296
Sequence Identity: 38% (18 aa)

LALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA
.|||||...   |... .  |||  |||.|. . ..|.... |||.|
IALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFA
S_TKc Spk396.AA S_TKc 284-538 13 3.9e-08 -57.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 284-538
Range on HMM: 1-231/231
Sequence Identity: 13% (40 aa)

FHKGGSDVFLGSGANGTVHLYRHRATDHPIALKTFELPNDIKAMTRKVNAIQSEAFILDVLGREDCFPTFLGCLEISTGKIGLAMDFVGDTMT--GESWT
....     .|.|| |.|.. ||. |..  |.|               . |..|  ||    . .   ..... .   ... . |...    .  |.  .
YEILR---KIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYC---DGDLGDLFD

LSHGMRK----LALSQHDWFALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDRPYFYRFSDEVKEKYRRREVYVH----I
. . ...      ..  .   ..  |.. |  .|..|..  ||| .| || .      .  | |||||.                       ..     .
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------------------TTFCGTPWYM

APECVLDDVLTSV-SSDV-------FQLGRLLTLMGGATTNADLTAIGNICRQSSQLC-------------RPSIDEVVA-----ELERMM
||| .      .  ..|.       . .    ..        .. .. .... |....             ||.. |. .      .   .
APEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Spk396.AA IKK 290-335 23 1e-06 18.74 In-house 4-49 (297) Show / Hide 
Range on Protein: 290-335
Range on HMM: 4-49/297
Sequence Identity: 23% (11 aa)

DVFLGSGANGTVHLYRHRATDHPIALKTFELPNDIKAMTRKVNAIQ
.  ||.|| | | ..||..|.  .| |...  .  ..... .  ..
CDRLGQGAFGNVYHWRHKKTGRKVAVKHCNHMSWMRCRWVWCREFE
Kinase Spk396.AA TKL 293-445 17 1e-06 19.77 In-house 1-201 (364) Show / Hide 
Range on Protein: 293-445
Range on HMM: 1-201/364
Sequence Identity: 17% (38 aa)

LGSGANGTVHLYRHRATD--------HPIALKTFELPNDIK--------------------AMTRKVNAIQSEAFILDVLG-REDCFPTFLG-CLEIS--
.|||. |.|.  ..| ..         ..| |.|   || .                    ... . .  . |  |.  .  | .    |.| |....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------TGKIGLAMDFV-----GDTMTGESWTLSHGMRKLALSQHDWFALALDIAKSLGRIHE--------KGFLMNDLKEDNCLLRKTPT------
         .|.... |...      ....                 |  . .|||||. .   |         .. .  ||| .|.|. .  |      
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYM

----GRWQAVIVDFGLA
      | . | ||||.
YNPNADWCCKICDFGLS
Kinase Spk396.AA Ciliate-C7 400-445 47 4e-06 16.05 In-house 108-149 (164) Show / Hide 
Range on Protein: 400-445
Range on HMM: 108-149/164
Sequence Identity: 47% (22 aa)

ALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA
| |||  |  ||.|....|||| || |          ||. |||||
AKDIAQGLYYIHSKNCVVNDLKMDNILIDY----NGNAVVCDFGLA
Kinase Spk396.AA LISK 292-316 36 0.212995 0.07 In-house 1-25 (296) Show / Hide 
Range on Protein: 292-316
Range on HMM: 1-25/296
Sequence Identity: 36% (9 aa)

FLGSGANGTVHLYRHRATDHPIALK
 .|.|. | |   .||.|  ..|.|
EIGKGFFGKVYKGTHRQTGQVMAIK