Gene Spk397 (Sea Urchin)

Spk397

Species: Sea Urchin
Alias: Spk397, SPU_014146
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: urch
Subfamily: urchA

Sequence

Name Sequence Type Origin Length Description Download
Spk397.AA Protein None 532 None Fasta, JSON
Spk397.kin_dom Protein Kinase Domain None 163 None Fasta, JSON

Protein domain

Protein domains of Spk397.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Spk397.AA urchA 287-485 54 2.8e-144 468.23 In-house 1-208 (208) Show / Hide 
Range on Protein: 287-485
Range on HMM: 1-208/208
Sequence Identity: 54% (113 aa)

LGSGANGAVHLYRHRATDHPIALKTFELPDEIKAMTRKVTAIQSEAFILDVLGREDCFPTFLGCLEISTGKIGLAMDFIGDTMTGES----WTLSR--GM
||.|..|.|||||||.||||.|||..|||.|.|.|.||....|.|..|..|||.|..||||.||.||...|.|.||.|.||.|||||    |.|..  .|
LGRGVYGTVHLYRHRQTDHPVALKVIELPKEYKKMRRKIECFQNEMQIHQVLGCEPWFPTFYGCCEICEDKVGMAMEFCGDEMTGESYTITWCLDKAMEM

RELALSQHDWLALALDIAKSLGCIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDRPY---FYRFSDEDKEKYRRKEVYVHIDPECALDDVV
|..||....|....||||..|...||||||.|||||||||.|||..|||.|.|.|||.||||..|.   ...|. ..|. ||    . || ||||||   
RQPALTRDQWMNVMLDIAEGLKVMHEKGFLCNDLKEDNCLVRKTEFGRWRAKIIDFGWACPCQMPFPACRMHFDQRQKQFYRYCHRCCHIAPECALDAQP

TSVSSDVF
 | ||||.
CSTSSDVY
Kinase Spk397.AA urch 287-488 38 3.8e-108 365.59 In-house 1-217 (217) Show / Hide 
Range on Protein: 287-488
Range on HMM: 1-217/217
Sequence Identity: 38% (84 aa)

LGSGANGAVHLYRHRATDHPIALKTFELPDEIKAMTR--------KVTAIQSEAFILDVLGREDCFPTFLGCLEISTGKIGLAMDFIGDTMTGES----W
.|.|..|.|||||||.|..|.|.|....|.....|..        .......||...........||.|.||..|. ....|.|.||||..||.|    |
IGRGTYGRVHLYRHRQTKQPVAIKMPCWPQNYTDMNEMEMEEWKANHERFTKEAMVHQLMSGHPYFPKFYGCVDID-DDLCLVMEFIGDKKTGKSYPLHW

TLS---RGMRELALSQHDWLALALDIAKSLGCIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDRPY-FYRFSDEDKEKYRRKEVYVHIDPE
...   ..|....||...||. |.||.... ..|..|||.|||||||.||.|...|||.|||.|||..|....|. ...|.|| .. |.. ..|.|| ||
CIHKSRMCMPNPHLSKWNWLNIAEDIVHGMMAMHDHGFLHNDLKEDNVLLEKRGHGRWHAVIIDFGWVCTMTMPFKMMHFPDEEMREYMHGHGYCHIAPE

CALDDVVTSVSSDVFQLG
|.||   .|..|||. .|
CVLDGQPCSIASDVYSVG
Kinase Spk397.AA urch-unclassified 287-488 28 8.9e-44 151.75 In-house 1-215 (215) Show / Hide 
Range on Protein: 287-488
Range on HMM: 1-215/215
Sequence Identity: 28% (62 aa)

LGSGANGAVHLYRHRATDHPIALK--TFELPDEIKAMTRK---VT--AIQSEAFILDVLGREDCFPTFLGCLEISTGKIGLAMDFIGDTMTGESWTLSRG
.| |. | | ..|| ..  | . |       |..  | ..   .    |  || .  ...    ||  .|  ..  .  ...|.|.||  |.   .|.. 
IGKGTFGKVFMMRHQREAVPVKVKMIHEHHNDYDYEMRMQNKLLMHERIMKEAMVHRLFADHPYFPRCYGMVKH-EDCPCIVMEFLGDKQTYTVYPLCQW

MRELA-----LSQHDWLALALDIAKSLGCIHEKGFLMNDLKEDNCLLRKTPT-GRWQAVIVDFGLACPCDR-PYFYRFSDEDKEKYRRKEVYVHIDPECA
  |       || | |.  ..|| . .   ||.. | |||| .| ||.. .   || | | |||.. . ..   . .|||. .. |.   .| |. ||  
IHERHKSNPALSKHHWINICMDICHGMHAMHEMDLLHNDLKSNNILLQWCDHDQRWHAYIIDFGMISTMTMPHKQRNFSDHEMREYMMGKIYHHMAPEIV

LDDVVTSVSSDVFQLG
|.   ||| ||.. ||
LYGQPTSVYSDIYSLG
Kinase Spk397.AA urchC 331-491 28 1.7e-15 46.44 In-house 57-223 (223) Show / Hide 
Range on Protein: 331-491
Range on HMM: 57-223/223
Sequence Identity: 28% (49 aa)

EAFILDVLGREDCFPTFLGCLEISTGKIGLAMDFIGDTMTGESWTLSRGMR-------ELALSQHDWLALALDIAKSLGCIHEKGFLMNDLKEDNCLL--
|| .. .. .   || ..| . |  . . .   ||||  .| .. |   |        .. ..    .| | || .    .|  | | || | || ||  
EARVGQMMSTCPYFPRMYGTVMID-ENMCIVTEFIGDKQQGKVYMLHDAMCPRKGCDPIPYVQKWNMVAIAEDIIRGVHFMHDFGLLHNDIKDDNVLLEH

RKTPTGRWQAVIVDFGLACPCDRP-YFYRFSDEDKEKYRRKEVYVHIDPECALD--DVVTSVSSDVFQLGRLL
||    || ..|.| |.      | ..  |.|   .  . .  ..|| ||  ||     .||.||..  | .|
RKE---RWHGCIIDMGMVSTMAYPPHQRGFNDVMPDHQKLYG-FIHIAPEV-LDIDGCQVSVASDIYSVGVIL
Kinase Spk397.AA TESK 382-445 41 5.1e-13 37.01 In-house 88-155 (292) Show / Hide 
Range on Protein: 382-445
Range on HMM: 88-155/292
Sequence Identity: 41% (28 aa)

ELALSQHDWLALALDIAKSLGCIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA----CPCDRP
||.||    . ||.|||. .  .|.||    ||   ||| |. .   ..||. |||||    |  | |
ELHLSWTQKIHLAYDIARGMSYLHSKGVFHRDLTSKNCLVRQRDNNQYEAVVGDFGLARVLGCMPDPP
Kinase Spk397.AA urchB 288-439 35 2.6e-11 37.14 In-house 8-162 (212) Show / Hide 
Range on Protein: 288-439
Range on HMM: 8-162/212
Sequence Identity: 35% (57 aa)

GSGANGAVHLYRHRATDHPIALKT------FELP----DEIKAMTRKVTAIQSEAFILDVLGREDCFPTFLGCLEISTGKIGLAMDFIGDTMTGESWTLS
| |  | | . ||| |  | | |       . .|    ||..  ||  | .. || |   .     || |.| | |      .|  |.|   ||  . | 
GRGTYGRVVIARHRQTKVPLAIKQPCWSDNYQSPNEMVDELHDATR--TRVTKEAMIHQLMSDSPYFPKFWGTLDIDN-DLCQAQEFVGCKKTGIGYPL-

RGMRELALSQHDWLALALDIAKSLGCIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA
       ||    .  | || | .  .|  | | |||| || || |    |. |||.|||..
--HEPPPLSMCNVVDIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGH-RYHAVIIDFGMV
Kinase Spk397.AA LISK 393-439 38 1.3e-08 23.93 In-house 106-152 (296) Show / Hide 
Range on Protein: 393-439
Range on HMM: 106-152/296
Sequence Identity: 38% (18 aa)

LALDIAKSLGCIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA
.|||||...   |... .  |||  |||.|. . ..|.... |||.|
IALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFA
S_TKc Spk397.AA S_TKc 278-532 13 3.3e-07 -71.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 278-532
Range on HMM: 1-231/231
Sequence Identity: 13% (39 aa)

FHKGGGDVFLGSGANGAVHLYRHRATDHPIALKTFELPDEIKAMTRKVTAIQSEAFILDVLGREDCFPTFLGCLEISTGKIGLAMDFIGDTMT--GESWT
....     .|.|| | |.. ||. |..  |.|                 |..|  ||    . .   ..... .   ... . |...    .  |.  .
YEILR---KIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYC---DGDLGDLFD

LSRGMRE----LALSQHDWLALALDIAKSLGCIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDRPYFYRFSDEDKEKYRRKEVYVH----I
. . ..       ..  .   ..  |.. |  .|..|..  ||| .| || .      .  | |||||.                       ..     .
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------------------TTFCGTPWYM

DPECALDDVVTSVSSDV-------FQLGRLLTLMGGATTNADLTAIGNICRQSSQLC-------------RPSIDEVVA-----ELERMM
 ||       .  ..|.       . .    ..        .. .. .... |....             ||.. |. .      .   .
APEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Spk397.AA IKK 284-329 23 8.5e-07 19.52 In-house 4-49 (297) Show / Hide 
Range on Protein: 284-329
Range on HMM: 4-49/297
Sequence Identity: 23% (11 aa)

DVFLGSGANGAVHLYRHRATDHPIALKTFELPDEIKAMTRKVTAIQ
.  ||.|| | | ..||..|.  .| |...  .  ..... .  ..
CDRLGQGAFGNVYHWRHKKTGRKVAVKHCNHMSWMRCRWVWCREFE
Kinase Spk397.AA Ciliate-C7 394-439 47 4e-06 16.19 In-house 108-149 (164) Show / Hide 
Range on Protein: 394-439
Range on HMM: 108-149/164
Sequence Identity: 47% (22 aa)

ALDIAKSLGCIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA
| |||  |  ||.|....|||| || |          ||. |||||
AKDIAQGLYYIHSKNCVVNDLKMDNILIDY----NGNAVVCDFGLA
Kinase Spk397.AA urchB 467-488 54 4.6e-05 14.47 In-house 191-212 (212) Show / Hide 
Range on Protein: 467-488
Range on HMM: 191-212/212
Sequence Identity: 54% (12 aa)

IDPECALDDVVTSVSSDVFQLG
| ||  |..  ||.|||||  |
IAPEVILHGQSTSISSDVFSVG
Kinase Spk397.AA TKL 393-439 27 0.00014 12.43 In-house 137-201 (364) Show / Hide 
Range on Protein: 393-439
Range on HMM: 137-201/364
Sequence Identity: 27% (18 aa)

LALDIAKSLGCIHE--------KGFLMNDLKEDNCLLRKTPT----------GRWQAVIVDFGLA
.|||||. .   |         .. .  ||| .|.|. .  |            | . | ||||.
WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLS
Kinase Spk397.AA TKL 287-312 26 0.003664 7.25 In-house 1-34 (364) Show / Hide 
Range on Protein: 287-312
Range on HMM: 1-34/364
Sequence Identity: 26% (9 aa)

LGSGANGAVHLYRHRATD--------HPIALKTF
.|||. | |.  ..| ..         ..| |.|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKF
Kinase Spk397.AA LISK 286-310 36 0.222095 0.01 In-house 1-25 (296) Show / Hide 
Range on Protein: 286-310
Range on HMM: 1-25/296
Sequence Identity: 36% (9 aa)

FLGSGANGAVHLYRHRATDHPIALK
 .|.|. | |   .||.|  ..|.|
EIGKGFFGKVYKGTHRQTGQVMAIK